Chemotherapy of Antibiotics (Part-04) Introduction & Mechanism of Action of Cotrimoxazole

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(1) Gram Staining techniques- • Gram Staining Techniqu... and Other staining techniques - • Microbial Staining | S...
(2) Microbial assay of antibiotics- • Microbial Assay of Ant...
(3) Route of Drug Administration- • Route of Drug Administ...
(4) Pharmacokinetic and Dynamics- • General Pharmacology C...
(5) Antibiotics Classifications- • Classification of Anti...
(6) Antiviral mechanism- • Antiviral Drugs | Clas...
(7) Factors Modifying drug action - • Factors Modifying Drug...
Antibiotics can be defined as pharmacological agents that selectively kill or inhibit the growth of bacterial cells while having little or no effect on the mammalian host. Bacteriostatic antibiotics prevent further replication of bacteria and therefore rely on an intact immune system to clear the infection, whereas bactericidal antibiotics kill the bacteria. Types of Antimicrobial therapy-
Selection of Antibiotic’s depends on many factors such as-
1. Identity of microorganism = Sample of Body Fluid and Staining Techniques
2. Antimicrobial susceptibility = Bacteriostatic and bactericidal along with a minimum inhibitory concentration (MIC)
3. Site of Infection (BBB)= Lipid solubility along with molecular weight and plasma protein binding of drugs
4. Patient-related factors- Immune system, Renal dysfunction, Hepatic dysfunction along with poor perfusion and state of pregnancy and lactation
5. Safety of antimicrobial or antibiotics
6. Cost of antibiotic therapy
7. Route of drug administration- oral, topical, or parenteral
Basic Classification of antibiotics-
1. Chemical Structure- Sulphonamides, Diaminopyramidines, Quinolones, Beta-lactam antibiotics, tetracycline, nitrobenzene derivatives, aminoglycosides, macrolides, lincosamide antibiotics, Glycopeptide antibiotics, Oxazolidione antibiotics, polypeptide antibiotics, nicotinic acid derivatives, azole derivative, Other antibiotics
2. Types of the organism which they are used
A. Antibacterial chemotherapy, the use of antibacterial drugs to treat bacterial infections
B. Antifungal chemotherapy, the use of antifungal drugs to treat fungal infections
C. Anthelminthic chemotherapy, the use of anthelminthic drugs to treat worm infections
D. Antiprotozoal chemotherapy, the use of antiprotozoal drugs to treat protozoan infections
E. Antiviral chemotherapy, the use of antiviral drugs to treat viral infections
3. The spectrum of activity- Broad and narrow spectrum
4. Types of action- Bacteriostatic of bactericidal
5. Source of antibiotics- Fungal, bacteria, Actinomycetes
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That's true, my whole class is dependent on pushpendra sir for cology.😂

[@inchrist5570]

Adding of animation and illustrating diagram pictures at the end of lecture are very effective. It helps us recall and remember when shown repeatedly. Rules: -never escape any part -do not rush escaping at the mids of lecture - stay focused till the end of the lecture 🤗🤗🤗 Thank you Sir 🥰

[@solutionpharmacy]

InChrist Yes you are correct. Skiping will not give full knowledge. Thank you so much for feedback

[@inchrist5570]

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[@khadijanasir8600]

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[@solutionpharmacy]

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[@solutionpharmacy]

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[@spanda909]

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[@solutionpharmacy]

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[@solutionpharmacy]

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[@solutionpharmacy]

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[@solutionpharmacy]

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[@Drrithika]

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[@solutionpharmacy]

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[@sameekshakatkar1503]

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[@solutionpharmacy]

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[@debasishsaha4976]

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[@saritamajhi8345]

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[@solutionpharmacy]

Thank you so much

[@jyotisundarrout9732]

The example of table.to.understand the.action of cotrimoxazole was nice sir

[@JatinGambhir676]

Thank you master❤

[@vrijendra_maurya100]

Sir please make microbiology playlist Thanks for your approach, very helpful

[@solutionpharmacy]

Already made

[@Drakashkumargangwar]

Sir , I m veterinary Student but the way u are teaching all concept getting clear of pharmacology

[@solutionpharmacy]

Great. Thank you for feedback

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[@solutionpharmacy]

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[@himanisingh3616]

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[@ashishsharma891]

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[@solutionpharmacy]

My pleasure

[@rupendragoswami8103]

Sir,pls gram positive or negative bacteria kon kon si disease ko krte he,or konsi generally drugs positive or negative me use hoti he,es pr pls full video bana dijye

[@yusraawan4289]

Your efforts are priceless Respect from Pakistan😊

[@solutionpharmacy]

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[@manishgoswami1770]

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[@solutionpharmacy]

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[@solutionpharmacy]

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[@solutionpharmacy]

Thank you for your feedback

[@nayabnoor1108]

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[@solutionpharmacy]

Bahut bahut shukriya

[@gulamhussain8545]

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[@solutionpharmacy]

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[@solutionpharmacy]

Sure. Thank you for your feedback

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[@solutionpharmacy]

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Mind blowing

[@RxDharmendra22]

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India best faculty 4 pharmacology

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[@solutionpharmacy]

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[@solutionpharmacy]

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[@solutionpharmacy]

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[@solutionpharmacy]

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[@solutionpharmacy]

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[@solutionpharmacy]

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[@solutionpharmacy]

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[@solutionpharmacy]

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[@SAJIDKHAN-lt9iy]

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[@solutionpharmacy]

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[@solutionpharmacy]

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[@solutionpharmacy]

Same feeling desr

[@mdnazirhussain7915]

Samjane ka tarika accha laga sir thanks mera kal ka comment ka reply nahi diye sir kuch puche the

[@solutionpharmacy]

Thank you. Bhai roj 1000 se upar comment aata hai, sabka ans dene ki kosis karta hu par sabka jawab dena possible nahi hai. Ye to aap bhi samjhte honge ?? Aur kisi ka naam yaad bhi nahi kar sakta.

[@vaishnavivanshakrithmath4540]

Sir your explanation is excellent sir👏,sir i am a pharm D student ,sir i have a question about this course ,sir sorry 🙏i am asking this question now bec i didn't get convenient ans from others about this course ,i am doing this course Bec it was suggested by a doctor in our family i don't have any idea about it,sir what is the scope for pharmD some members are saying in India it is of less scope and it has scope in foreign,but if we want to go to foreign means we should write exams like in MCQs type and we should pay 1lak for it and very few chances of passing.sir i am confused about the future in this middle of this course 🙏sir pls guide me sir.🙏

[@solutionpharmacy]

You are right. Unfortunately in India its scope and objective is not so clear. Its scope is equivalent to Mpharm right now

[@vaishnavivanshakrithmath4540]

Sir then no choice,i should go to foreign countries, sir i am planning to go to USA after my pharm D,sir what kind of books i should refer for qualifying their entrence test ( like MCQs type)Bec in pharmD we won't refer MCQs like we will write question and ans type,sir so i don't have idea about how questions may come,sir can u suggest me pls🙏

[@solutionpharmacy]

We have MCQ of selected subjects in our app

[@vaishnavivanshakrithmath4540]

Thank u sir for your guidance, thank u for your valuable time🙏🙏🙏

[@abdulhameedaryoubi808]

Sir can u explain when the drug Cotrimoxazole or any drug show ADR (adverse drug reaction) is it depend on time or is it depend on dose of drug? Onething that i didn't understood by combination of two drugs Hows we can give this drug name Cotrimoxazole. I hope u will not mind sir.. Ur sincerely student Abdul Hameed Aryoubi From Afghanistan.

[@solutionpharmacy]

I have uploded a video on ADR please have a look. If still you wont get then let me know. I will explain you

[@abdulhameedaryoubi808]

@@solutionpharmacy Thank you Sir I will see Inshaa Allah!! And what the name Cotrimoxazole Sir

[@sanjaykushwaha2227]

Right hai sir

[@championabi7930]

Sir sulfonamide ko hum respiratory tract infection mai use kar sakte hai ki nahi (alone)

[@dr.chandrakantmagdum1735]

AIDS पेशंट में Cotrimaxzole adverse effect बनेगा या उसे Cotrimaxzole की पहले ही allergic reaction होने से ज्यादा ADR effect दिखेगा

[@dr.ankushnikam2551]

Sir folic acid deficient me aal ready megaloblastic anaemia is present, usme drug kya interfere keta he?

[@solutionpharmacy]

Nahi ye to microorganism ke liye specific hai

[@nishantsen6820]

It can kill MRSA vrsa or anaerobes microbes?

[@prernasati5505]

Sir mujhe phla wale video maine dihydro pterate synathase enzyme tha but in video ma folic acid synathase he ?? Ha dono ma alg alg enzyme ka use hua hee

[@solutionpharmacy]

Action ek hi hai

[@shubhamhumbe5]

Sir sulfonamides ko hi trimethoprim bolte hai kya

[@pratibharajpurohit4406]

Sir ...dental pharmacology k topic pe vdio banaiye na sir...

[@solutionpharmacy]

Sorry syllabus to hame pharmacy ka hi follow karna hai

[@pratibharajpurohit4406]

@@solutionpharmacy ok sir no problem..

[@deepakyadav-ru5oj]

Sir what the role of seratopeptides??

[@subibhadouria9919]

Can we use cortimoxalone alone?? , or it is necessary to combine with sulfonamide??

[@solutionpharmacy]

That will not be so effective

[@subibhadouria9919]

Thnq soo much sir for replying

[@m_raj9760]

👌👌👌

[@komalkaur8564]

Can I take this during fat malabsorbtion

[@solutionpharmacy]

Means

[@dr.chandrakantmagdum1735]

मैंने Cotrimaxzole का adverse effect ऐसा देखा है की Steven Johnson हुआ जो की बहोत ही denger होता है

[@sufyankhan7507]

Cotrimoxazole sulraramite ka hi part hai kya?

[@solutionpharmacy]

Sorry samjha nahi

[@divyasharma4388]

Sir macrolides tetracycline and quinolons or aminoglicons

[@solutionpharmacy]

Please wait. Cant uplload all in just 01 video. It will come every night

[@funhub352]

❤❤

[@prashantraghav4134]

Sir pyrogenic bacterial injection kiya hai

[@vishwakadam6096]

Sir ,ye penicillinase sensitive penicillin or penicillinase resistance penicillins ..?? kuch samaj nhi aa rha ?? plz jaldi se video leke aayiye ...plz

[@solutionpharmacy]

Vishwa Kadam Aayega. Penicilinase sensative matlab aisa penicillin jo iske presence me deatroy ho jaye (Penicilinase= Enzyme made by bacteria which destroy penicillin)

[@awaneeshtripathi8110]

Sir its request not compulsory if you could tell what are the exam which we can give while doing b. pharmacy. Other than gpat, niper, bits, please share it

[@solutionpharmacy]

awaneesh tripathi You want to know about exam but for which - job or study ?

[@awaneeshtripathi8110]

@solution pharmacy sir I want to know for study purpose in India as well as foreign

[@solutionpharmacy]

awaneesh tripathi Really sorry. I do not have much idea about it.

[@Anastesia2]

🌟🌟🌟🌟🌟

[@spanda909]

Actually sir very simple part .main part to sulphonamide tha..wese sir ye long kis prakar aayega ??

[@solutionpharmacy]

Har video long nahi hoga. Jaja jarurat hogi waha thoda lamba jaayega

[@spanda909]

@@solutionpharmacy long se Mera MATLAB long question. Galti se question lekhna bhul gaya

[@solutionpharmacy]

S Panda aaj ka model question check kariye ya isi video ke description box se model paper download kariye.

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Aaj ke time per bhi ye medicine kam karega kaise jane

[@solutionpharmacy]

RAHUL KUMAR kaam kar hain kyunki ye abhi current classification me hain

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I nominate your name for "padmashri"...

[@solutionpharmacy]

Ha ha ha. Thank you. Hum us layak nhi hai sir.

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Sir aaj part 5 ni aaega kya🥺🥺🥺

[@solutionpharmacy]

Nahin aaj notes ke winner ka video tha

[@yogeshmittal4702]

@@solutionpharmacy okk sir..

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Sir hm apko nhi naraj krenge hmm sequence vaise dekh rahe sir

[@solutionpharmacy]

Great

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Group Mai add Kasai hongaye sir

[@solutionpharmacy]

Description box me tarika hai