CHT Chromatography Media: 5 Essential Facts

#chromatography #biopharma #bioprocess
For over 30 years, CHT™ Ceramic Hydroxyapatite Chromatography Media has been a trusted, proven purification solution for many biopharmaceutical manufacturing processes. CHT provides exceptional removal of impurities when other chromatography resins fall short to provide the same level of purity.
In this webcast, explore the essential facts and benefits of this chromatography technology. The 5 Essential Facts:
• CHT is eco-friendly and can help achieve your sustainability goals.
• CHT is considered the gold standard for impurity removal - aggregates, leached Protein A, endotoxin, DNA, and HCP.
• CHT provides flexibility in your method development - giving the ability to achieve high-purity product.
• CHT provides unique selectivities, enabling fewer steps in the purification workflow leading to improved process economics.
• CHT packs as a non-compressible resin making packing easier than packing compressible resins in a column.
00:33 - Overview
00:52 - CHT is the gold standard for impurity removal (inc. what is CHT and how it works)
03:26 - Monoclonal antibody (mAb) aggregate removal case studies
04:26 - CHT provides flexibility in your method development
06:32 - Virus purification case studies
07:14 - Single-step plasmid purification
08:04 - CHT provides unique selectivities that can lead to improved process economics
10:32 - Bispecific antibody (bsAb) case study
10:58 - Protein purification case studies
11:15 - CHT packs as a noncompressible media, making packing easier
14:00 - CHT packing tips: "do's" and "don'ts"
15:45 - CHT is eco-friendly and can help achieve sustainability goals
16:29 - Sustainable workflow example
17:48 - Summary
18:16 - Support Resources
18:58 - Audience Question and Answer (Q&A)
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