Coagulation cascade | Human anatomy and physiology | Health & Medicine | Khan Academy

[@MuhammadZubair-mp6cm]

I studied Robbin's pathology, I studied guyton and believe me, these 14 minutes have stood more valuable for me than those 20 pages of textbooks

[@kerrybiery6360]

Exactly! Those who really know how complicated this whole coagulation thing is have great respect for this presentation. Of course, this presentation is targeted towards an entry-level allied health students: nurses, paramedics, respiratory therapists, etc. I am a nurse (now retired, thank God) with an extensive background teaching allied health students, and many years of experience in ICU, PACU, ER, and Med-Surg. and I’ve forwarded these coag. videos to colleagues who’ve enjoyed them as I have.

[@rishavmadhukalya2]

World needs more teachers like you...

[@daisymay8488]

Nicely broken down and very easy to follow! I swear, I spend an hour just trying to read about this stuff, but watching a 15 minute video and I completely grasp the concept now! Thanks a lot!

[@HampsteadO]

10 years out of college and I tried to learn it in multiple occasions from so many different textbooks and you did it in 14 minutes. Thanks 🤣😍

[@christinelouis7493]

Studying this cascade from the pov of different subjects at college and never been able to carack it doen like today

[@hannahfuller6088]

"Assuming you have those friends" LOL

[@mylynnwoods1565]

Lol. I can relate

[@markblaze4746]

I felt less dumb after watching this video, my lecturer talked like a machine gun

[@jamesalipio1631]

our lecturers always have

[@tatner7146]

It's just wonderful how you organize notes so that it can be easily remembered! Love your videos!

[@abiazizahmed2808]

A living legend...man u dont know how much u help...i can only say God bless u

[@seafoam7095]

Been studying this sh*t for ages and you taught me the easiest way to remember it! I like how you said about the numbers (factors) ultimately leading to the 'goal.' And yes it worked for me because I'm bad at counting lmao

[@wellman15able]

"lets say you weren't very good at counting" omg that entire part brought my sides into orbit

[@Sali_Levi]

Extremely clear explanation!! amazing

[@robynneRN]

This was fascinating. I am learning about anti-coagulants in nursing school, and this really helped me with the foundation as to WHY we bother with PTT, PT/INR lab values. Thank you!

[@Schatten2712]

honestly, after the complement system this is like a walk in the park

[@gh-ps5es]

It's the opposite for me? But this was still pretty easy to understand. Guess it depends on who u r learning from as well

[@kkomber6888]

@@gh-ps5es how is it easy for you I am dying trying to learn them 😂💔

[@yksci2740]

I’m about to cry this video helped me more than I could imagine

[@jedidiahmanna3863]

Omg …. This video is so good. I had to pause it halfway to give a thumbs up and comment. I am phlebotomist, and I have been wondering how anti Xa works. With all the video I have gone through online. This video, I believe is the best. The cascade is well explained with tricks to help me remember. I will love to explain to some of my patients this amazing biological process in our human body. Thank you for this amazing 🤩 video 🙏

[@shalomsiansangu9179]

Best best vedio on coagulation cascade I've come across

[@riyaroka]

Fell in love with the explanation, its saving the life out of me. Thank you sm❤️❤️❤️

[@dr.h.a.bpediatrics8999]

Thank you very much sir .. Thats how medicine should be explained to doctors .. 👍

[@merhanessam]

this video helped me alot ....i really spent days to try to understand this part :( .....but now everything is clear for me....thank u so much

[@Andrew-kh7rz]

i really spent 2 to three fcking days to get used to insertions and origins of the muscles as well as the lumpy bits

[@kthekactus]

This was amazing! I was struggling to fully understand my uni lecture on coagulation but this video made it so much easier by going thru the steps diagrammatically and vvv simply! v relevant + to the point too, no waffle!!

[@joshuaharris5605]

Almost a decade later and still the best video on the net to learn clotting factors

[@lobarita]

You have helped me understand this thru the past several months. It took a while, but it's all coming together. Thank you.

[@AJohnson0325]

thanks! I have to study 140 pages of notes on anticoagulant, anti-platelet, and fibrinolytic drugs. This is going to help me a bunch.

[@toddfennimore6625]

Wow! Amazing explanation - I have heard or read over a dozen lectures or articles on the clotting cascade, and I feel as though I finally understand it and can retain it.

[@enoente1888]

I tried to learn this a couple of years ago for my exams and I must confess, I could not answer the question. Listening to this video and watching you create such a complex concept so simply is so good, thank you

[@nadaramadan5709]

amazing... i am an egyptian vet and i love your videos so much 💙💙💙

[@hadjerswift4519]

This is very helpful and easy to understand ,also loved the tricks to memorize it better

[@mutelarsorhougbe4606]

This was so so very well explained! And I love the little things to help us remember it!

[@hana-bt7rf]

best video? no best video EVER!!!

[@mandaparker21]

Videos like this make me love KZbin. Great job! I loved the visuals.

[@CollinScottTibbitts]

One of the best coagulation videos out there!

[@jcvn8915]

No way i can describe how much of a great helpful and intelligent human being you are

[@girldetective18]

God bless you!! You explain this so well and oh my gosh I needed this!

[@admoh8835]

This video deserves noble prize in education

[@nontobekomdluli]

this is amazing...you are God's sent. my teacher makes it look so complicated...

[@sbbperson]

I clicked on your video by accident. But your video and explanation skills were so good, I subscribed. Thank you for the information, this is great!

[@preciousbankole6350]

Wow this explanation was amazing

[@pippaharris-patel6490]

"Wouldn't it be easier if you called 5 friends and then those friends each called 5 friends?" I clearly don't have friends, I am watching this video on a Saturday night with a hard seltzer.

[@BeautiFAHT]

This is the absolute BEST video I've watched on intrinsic/extrinsic pathways! Such a clear understanding now! THANK YOU!

[@befriendwtech]

wow this video is super good! im gonna leave a comment here! ...and then i saw who published it; OH! KHAN! i knew it. thanks khan academy ;)

[@cat5220]

thank god for this channel... about to singlehandedly save my degree!!

[@JuanCarlosMedinaAgredo]

Great video, greetings from Colombia Armenia U. Humboldt

[@gangabahadurlimbu1239]

Brilliant Lecture.

[@kmirandakondo]

This video is an A for brilliant explanation

[@gazamax3]

then is one of the best videos ive ever watch in my whole medical school. THANX ALOT

[@habib080]

Which medical school do you go too?

[@gazamax3]

Ha080 it is in Turkiye, Ankara, yildirim beyazit university

[@МилорадЈеремић21]

omg, you are my hero, god bless you, im gona smash this knowledge right to my profesor face, thank you so much!!!

[@ohheyitsadrian4412]

Just Khan Academy saving the day again. thanks!

[@janineschwegman7920]

Most beautifully explained - thank you!

[@tiffanyann9936]

Thank you. This was much easier to follow than the first two I watched.

[@mc_dibia]

this was beautifully done. it made so much sense. if my lecturer only showed this video instead of talking for an hour

[@Abdulelah_]

The best explanation I ever had in coagulation cascade I wish you where our lecturer 🥹

[@JohnCitizenCitizen]

such a good teacher. thanks for making this!

[@thinoronha]

Great explanation!

[@dareenashgar1965]

Easiest way to remember it, thank you so much!

[@s.m.ridwanulislam3233]

owao it is amazing and amazing ...... great effort

[@Vermazeren]

"Wonderfully explained! You have such a great voice to listen to. Have you ever thought of telling the whole story, starting with the vasoconstriction and platelet aggregation phase? And what about the tPA phase for reversing coagulation? Right now, you only discuss AT and a bit of plasmin, but since platelets play a crucial role in delivering thrombin, it would be great to include details on the role of TXA2 (vasoconstriction and platelet attraction) and how fibrin strands connect to platelets through GP2b/3a."

[@Vermazeren]

Another great point is how the TF-VIIa complex also activates IX, allowing it to activate X independently of VIII-albeit very slowly. Ultimately, IX needs VIII to speed things up, since VIII alone can’t activate X without IX. Just an coagulation lover here :))

[@DC-qk7hx]

Brilliant delivery. Thank you!

[@nooranoor6221]

I alway look for videos from Khan academy .. always useful .. many thanks ❤️

[@raspberry765]

"you'd become one large walking clot" HAHAHAHAH

[@ForYourConsideration]

Thank you for the excellent lesson. The amplification sequence explanation (07:16) was very helpful in understanding the significance of the activation process.

[@shannonhogan5859]

Wow - great little story to remember the factors :) thanks!!

[@imsamanthaswift]

i just love the way you teach along side how to remember it. i wish my teachers were like this! :/ thanks

[@Jongui_]

Seriously, this video is amazing.

[@memoboy4141]

Thanks for existing

[@ManpreetSingh-gc6bo]

it's just awesome! you simplified it like a boss

[@TheRosagirly]

such a clear simple explanation thank u!!

[@MasterThil29]

It's not easy getting your head around this but you did a great job of explaining all the pathways. Thanks.

[@1412Z]

Thank you so much for your efforts in doing this video!! God bless you

[@Unarine.Ratombo]

thank you so much for this video, so easy to follow

[@randa2113]

you have just saved me !!! thank you so much for the video

[@cathg.956]

im so happy i found your page!

[@giulyt.5468]

Thanks for this amazing explanation!!

[@jhessiecdj1211]

thank you Patrick for the very informative lecture :)

[@sudharshan6257]

this guy is just awesome..

[@ranikhan3963]

Helpfull in understnaging and memorizing too ...!!! Thank you ....!!!

[@kunsang8977]

Great help. Big thanks

[@徐丹-u7f]

it's REALLY helpful, thanks.

[@jazzlikesyoochoob]

this video is gold

[@LitaMonroe1913]

This is exactly what I'm looking for! This is very helpful!

[@ivo3185]

I- I finally understand. Thank you so much! Incredible video. You made the topic really easy to memorize!

[@kolabindupavani]

Loved it. Thankyou so much man! ✨🔥💯

[@jessc7952]

you just explained in 15 minutes what my lecturer failed to do in 3 hours

[@jl981015]

Clotting factor 2 is actually Prothrombin, not thrombin. Thrombin is 2a. Great Video!

[@PonzooonTheGreat]

Wow, thanks! My lecturers are shit! You explained in 15 minutes what my lecturer could not in an hour. What's heparin? I hear that comes into play when breaking down a clot or something.

[@doktorone1666]

Heparin is basically a natural anti coagulant protein . Natural because is made in your body. You can use it before performing a cannulation , you put some heparin on the tip of the needle to prevent blood clots from forming and eventually close the tip of that needle, which would make injecting drugs into the vein harder.. :P

[@lukask.9870]

Heparin promotes Antithrombin 3 (a serine protease). Antithrombin 3 inactivates Factors 2 and 10.

[@nalapisa]

Doktor One True, only heparin is NOT a protein but a GAG (glicoseaminoglican) polymer.

[@palshah2463]

PonzooonTheGreat it's an anticoagulant made by liver which keeps the blood in liquid form when the blood capillaries are not hurt

[@Gossypol]

Does Prekallekrein and HMW Kininogen also includes in the intrinsic pathway? Please explain anyone. Thankyou.

[@douniasaleh8211]

Thank you so much, I always come in this channel for help and you guys never disappoint me

[@monkeydpaps1453]

Superb video! Very educative!

[@zahraaammer8700]

You did such a magnificent work over here Well done

[@LauraHernandez-dt9bb]

Wow! You really helped me learn this material. I was so confused by my professor. Thank you !!

[@dopechick457]

U made it so easy

[@primeascendant797]

Zymogen forms are one of the most amazing things in the body, in my view. Your body is locked and loaded to do so many things, it's very efficient. Especially in this case, when something soluble is turning into something insoluble.

[@danschmeidler]

Fantastic. This is just incredible. Great job.

[@joaovitorpimentel2140]

Awesome video! Maan... That helped me a lot! Thank you.

[@enterpriserjohn]

This guy is good

[@CristianoRaashid77]

This was tooooooooooooooooooo good!!! Thank you so muchh

[@virgochic8415]

Super explanation thanks

[@LaurenAWhite-cu9rc]

Incredibly helpful! Thank you!

[@haileybailes3160]

This was so helpful! Thank you so much.

[@fathimazahranoorgat5334]

Really helpful thank you!!!

[@noayoung2849]

I love you and this video, thank you so much

[@ndapewa3245]

Thank you. Really made a big difference 👏🏽