Colliding Ribosomes Function as a Sentinel for Cellular Distress

Air date: Wednesday, February 24, 2021, 3PM
Duration: 00 :54 :04
Description:
Wednesday Afternoon Lecture Series
Dr. Green is a Bloomberg Distinguished Professor of molecular biology and genetics at the Johns Hopkins University School of Medicine. She also has been a Howard Hughes Medical Institute investigator since 2000. Her research on ribosome structure and function in bacterial, yeast, and human cells has revealed fundamental mechanisms of protein synthesis.
Dr. Green will describe her laboratory's recent efforts to define how ribosome elongation distress is connected to cellular signaling pathways involved in cell fate determination. She will discuss how colliding ribosomes are central to this activation, and she will elucidate how a combination of approaches - from genetics, to biochemistry, to structural biology, to genomics - can reveal such insights.
For more information go to oir.nih.gov/wals
Author: Rachel Green, Ph.D., Bloomberg Distinguished Professor of molecular biology and genetics, Johns Hopkins University School of Medicine
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