Components of ECM

[@RohitPant04]

Incase someone wanted a brief summary of functions, Functions of the following components: Collagen - Collagen has great tensile strength, and is the main component of fascia, cartilage, ligaments, tendons, bone and skin. Along with elastin and soft keratin, it is responsible for skin strength and elasticity, and its degradation leads to wrinkles that accompany aging. Proteoglycan - Provides hydration and swelling pressure to the tissue enabling it to withstand compressional forces. Lamina - Laminins also provide adjacent cells with a mechanical scaffold and biological information either directly by interacting with cell surface components. Fibronectin - Cellular fibronectin is assembled into the extracellular matrix, an insoluble network that separates and supports the organs and tissues of an organism. Fibronectin plays a crucial role in wound healing.

[@knowledgeinsights5867]

Thanks dude!

[@EugeneAnyango]

Thank you I really needed this

[@fedepheeka]

I've spent hours trying to understand all of this and then I saw your video THANKS YOU SAVIOUR

[@phindosomdakakazi1495]

wow. you are amazing sir. you are moving at a very well pace and audible enough. everything you say is just so clear and simple. I need more of your videos.

[@damoonsheidai4469]

thank you, its clear for me now :) would be nice if you explained elastin too!

[@ashleyng7466]

Your little comments about the whiteboard and accidentally crossing out movement makes this lecture more enjoyable, thank you for the clear lecture!

[@keighleyhayes]

you can bet your bottom dollar

[@SandWraith123]

There's some confusion here with what constitutes a GAG and a proteoglycan. GAGs (shown here as red lines) complex with core proteins (black line) to make proteoglycans (erroneous labeled here as a GAG). These proteoglycans can then complex with an HA backbone to make a superstructure. Also important to note that HA is in fact a GAG within itself, that is unique among the GAGs in that it does not complex with proteins directly to form a proteoglycan, but rather, serves as a foundation for other proteoglycans to be complexed with it via serine residues.

[@muntahanoormuskan6431]

Probably the best video I found on this topic

[@zainabmohamad4784]

Please keep going and thanks a lot for your hard work … you are so helpful .. dean tell you enough

[@arydior803]

This video was very helpful! GRACIAS, Greetings from Colombia😊

[@pockocmocvidz7513]

Ow yeah! Great explanation! Thank you very much man.

[@ALASKAOO7]

Bravo! una bella lezione - mi hai fatto capire olte cose su ECM

[@gurlerakpinar9134]

Thank you very much man, simple and easy.

[@peters.8719]

I thought the lamina are the intermediate filaments found in between chromosomes and the nuclear envelope and helps give the envelope structure. Then the laminin are the multi-adhesive matrix proteins that cause the cross linkage to collagens and Proteoglycans.

[@Caromadero31]

Yeah, I think you're right

[@nellzybellz6155]

you are correct. I believe he meant to write laminin, which is most definitely not the same as lamina.

[@ataconazi]

he meant laminin.

[@drhumupower8570]

There are a number of different biological constructs called "lamina" - anything that forms a layer is basically a lamina. Laminin happens to be a lamina associated protein.

[@stacymeichle3995]

Awesome videos! I'm reviewing for a grad level cumulative cell biology exam and these are helpful!

[@ellesrevisionsession]

You're good at explaining. Thanks.

[@saadsultan7521]

good efforts sir! you explain and draw very good ,only you should need to focus on arrangement and planning of your lecture ,you were forgetting some points of collagen and were adding it later on......otherwise you teach excellent !!!

[@FrenzyTrend]

Great video! thank you man you made it simple and easy to understand

[@rebinem2584]

Great

[@madeinengland1111]

Brilliant and very informative thank you

[@rajendransharon7515]

Thanks alot sir...the lecture was simple and excellent..

[@applewhite9403]

Tnqq so much, keep up the good work

[@josephdahdouh2725]

Wow, brilliant.

[@taniahariadi2435]

👍👍 be success

[@Lily55n]

Thank you so much! God bless you :)

[@akshisharma1927]

It was great but please explain elastin too. Thanks :)

[@sriradhaganguli7660]

Well explained

[@itsgreat8518]

Thank you so much

[@jyggyhobyt]

thanks, very clear and helpful :)

[@dbahelmi5230]

finally i understand this part, thank you :D

[@minaisconfused4668]

THANK YOUU I LOVE YOU

[@shanskyeross5573]

come for the fibronectin, stay for the cute boy

[@rayannawilliams4154]

😂

[@emirmuvaffak5331]

thanks you .

[@abnoosmoslehshirazi8948]

helpful :) thnks

[@yarakitty2738]

Thank youuuuuuuuu

[@ritusahni1858]

sir please give a class on extracellular matrix of animal

[@aishahhearts8294]

thanks that was helpful

[@aryaa3998]

That helped, thanks :)

[@caterine4604]

Thankssssss

[@desmondkisa8767]

Someone has exams tomorrow 😂😂

[@rayannawilliams4154]

Yup😂

[@KRAPYBARA84]

Wtf is a trimer lol?

[@s.m.motors720]

Hindi language video please

[@jb44421]

It's Laminin, not lamina.

[@gurlerakpinar9134]

Thank you very much man, simple and easy.