Components of ECM

[@RohitPant04]

Incase someone wanted a brief summary of functions, Functions of the following components: Collagen - Collagen has great tensile strength, and is the main component of fascia, cartilage, ligaments, tendons, bone and skin. Along with elastin and soft keratin, it is responsible for skin strength and elasticity, and its degradation leads to wrinkles that accompany aging. Proteoglycan - Provides hydration and swelling pressure to the tissue enabling it to withstand compressional forces. Lamina - Laminins also provide adjacent cells with a mechanical scaffold and biological information either directly by interacting with cell surface components. Fibronectin - Cellular fibronectin is assembled into the extracellular matrix, an insoluble network that separates and supports the organs and tissues of an organism. Fibronectin plays a crucial role in wound healing.

[@knowledgeinsights5867]

Thanks dude!

[@EugeneAnyango]

Thank you I really needed this

[@fedepheeka]

I've spent hours trying to understand all of this and then I saw your video THANKS YOU SAVIOUR

[@keighleyhayes]

you can bet your bottom dollar

[@damoonsheidai4469]

thank you, its clear for me now :) would be nice if you explained elastin too!

[@phindosomdakakazi1495]

wow. you are amazing sir. you are moving at a very well pace and audible enough. everything you say is just so clear and simple. I need more of your videos.

[@ashleyng7466]

Your little comments about the whiteboard and accidentally crossing out movement makes this lecture more enjoyable, thank you for the clear lecture!

[@muntahanoormuskan6431]

Probably the best video I found on this topic

[@SandWraith123]

There's some confusion here with what constitutes a GAG and a proteoglycan. GAGs (shown here as red lines) complex with core proteins (black line) to make proteoglycans (erroneous labeled here as a GAG). These proteoglycans can then complex with an HA backbone to make a superstructure. Also important to note that HA is in fact a GAG within itself, that is unique among the GAGs in that it does not complex with proteins directly to form a proteoglycan, but rather, serves as a foundation for other proteoglycans to be complexed with it via serine residues.

[@zainabmohamad4784]

Please keep going and thanks a lot for your hard work … you are so helpful .. dean tell you enough

[@ALASKAOO7]

Bravo! una bella lezione - mi hai fatto capire olte cose su ECM

[@peters.8719]

I thought the lamina are the intermediate filaments found in between chromosomes and the nuclear envelope and helps give the envelope structure. Then the laminin are the multi-adhesive matrix proteins that cause the cross linkage to collagens and Proteoglycans.

[@Caromadero31]

Yeah, I think you're right

[@nellzybellz6155]

you are correct. I believe he meant to write laminin, which is most definitely not the same as lamina.

[@ataconazi]

he meant laminin.

[@drhumupower8570]

There are a number of different biological constructs called "lamina" - anything that forms a layer is basically a lamina. Laminin happens to be a lamina associated protein.

[@arydior803]

This video was very helpful! GRACIAS, Greetings from Colombia😊

[@pockocmocvidz7513]

Ow yeah! Great explanation! Thank you very much man.

[@ellesrevisionsession]

You're good at explaining. Thanks.

[@stacymeichle3995]

Awesome videos! I'm reviewing for a grad level cumulative cell biology exam and these are helpful!

[@gurlerakpinar9134]

Thank you very much man, simple and easy.

[@FrenzyTrend]

Great video! thank you man you made it simple and easy to understand

[@josephdahdouh2725]

Wow, brilliant.

[@tebaaljumaily3595]

Great❤ what happened to u why aren’t u upload more videos؟

[@madeinengland1111]

Brilliant and very informative thank you

[@rajendransharon7515]

Thanks alot sir...the lecture was simple and excellent..

[@Lily55n]

Thank you so much! God bless you :)

[@applewhite9403]

Tnqq so much, keep up the good work

[@saadsultan7521]

good efforts sir! you explain and draw very good ,only you should need to focus on arrangement and planning of your lecture ,you were forgetting some points of collagen and were adding it later on......otherwise you teach excellent !!!

[@rebinem2584]

Great

[@akshisharma1927]

It was great but please explain elastin too. Thanks :)

[@taniahariadi2435]

👍👍 be success

[@sriradhaganguli7660]

Well explained

[@dbahelmi5230]

finally i understand this part, thank you :D

[@jyggyhobyt]

thanks, very clear and helpful :)

[@itsgreat8518]

Thank you so much

[@minaisconfused4668]

THANK YOUU I LOVE YOU

[@yarakitty2738]

Thank youuuuuuuuu

[@ritusahni1858]

sir please give a class on extracellular matrix of animal

[@shanskyeross5573]

come for the fibronectin, stay for the cute boy

[@rayannawilliams4154]

😂

[@abnoosmoslehshirazi8948]

helpful :) thnks

[@emirmuvaffak5331]

thanks you .

[@aryaa3998]

That helped, thanks :)

[@aishahhearts8294]

thanks that was helpful

[@desmondkisa8767]

Someone has exams tomorrow 😂😂

[@rayannawilliams4154]

Yup😂

[@KRAPYBARA84]

Wtf is a trimer lol?

[@AnimeUni-versed]

Thankssssss

[@s.m.motors720]

Hindi language video please

[@jb44421]

It's Laminin, not lamina.

[@gurlerakpinar9134]

Thank you very much man, simple and easy.