Immune System, Part 1: Crash Course Anatomy & Physiology #45

[@crashcourse]

Pssst... we made flashcards to help you review the content in this episode! Find them on the free Crash Course App! Download it here for Apple Devices: apple.co/3d4eyZo Download it here for Android Devices: bit.ly/2SrDulJ

[@Scotticus25]

The animations were absolute quality.

[@anti_MATT_er]

+Scotticus25 The faces were so cute, haha.

[@Lumamaster]

+Scotticus25 best animation 11/10

[@crashcourse]

+Scotticus25 This was probably my favorite episode so far in terms of animations. There's some great stuff coming up too! +Thought Cafe is amazing. -Nicole

[@TheChipmunk2008]

+Scotticus25 Literally scrolled down to say 'the animations are awesome'. Saw this. +1 :D

[@M_Chen333]

+CrashCourse TOTALLY

[@nelliesimonian8168]

the fact that I watched this 10 minute video and understood everything astonishes me. It also amazes me how college professors literally elongate so much of their lectures, sometimes talking for 3 hours straight to tell us the same information in this video.

[@Tepid24]

You guys are amazing. Managing to pull off a cliffhanger on an educational video is quite the deed.

[@kevinbutton4580]

Right it's kinda scary

[@Weston29406]

+Tyrannosaurus Rex Didn't even think of it that way. It is impressive.

[@minimooster7258]

My Ancient Greek teacher did the same when talking about the Minoiens. He mentioned "in passing" that they could have been Atlantis and then said that the lesson was done!

[@benaaronmusic]

+Tyrannosaurus Rex - Very impressive, indeed!

[@iggyg1370]

If phagocytes can swallow invaders, like bacteria and viruses, then how can anyone be sure that vaccines that are made of inactive viruses really work? Inactive viruses do not reproduce, and do not cause infection, vaccines with weaken viruses may replicate, but also do not cause infection. Does the immune system really need to produce antibodies, for viruses that do not cause infection?

[@tohdohsibir]

As both a medical student and artist, I find this blend of animation and science all sorts of awesome. 👍

[@moxi_floxi]

This is, by far, the most adorable portrayal of the immune system I have ever seen. Props to Crash Course.

[@alex_zetsu]

It certainly was at that time. Japan made a longer portrayal. It's called Cells at Work (all but three episodes the immune system is featured prominently)

[@denisem35]

I am a visual learner and let me just say this.......this FINALLY makes sense!! I love those animations!! Besides it being informative, it's really entertaining. Loved it!!

[@insainsin]

Literally the best animations yet. Absolutely flawless.

[@thepikarivera7706]

empCarnivore I agree

[@WadcaWymiaru]

*Kurzgesagt* is better...

[@rachelfaith3578]

@@WadcaWymiaru nope

[@nandamulya3117]

Is ur profile pic mugi from K-On?

[@darrellsimon4462]

Smiley face phagocytes

[@rosiekr901]

you there stop looking at the comments section and study

[@tbsjgmyt]

Got me

[@sanaearthfire3833]

@@tbsjgmyt N ME!))))

[@ahahxx7068]

😂😂 ok I will go now

[@spacier2988]

lol got me too xD

[@bintzubair]

Likes comment to proceed scrolling

[@liquidwood4064]

This guy: "Our immune system is very sophisticated." Immune system: "My solution to this problem is to BURN EVERYTHING TO THE GROUND!"

[@888starkid]

I just wanna give a HUGE thank you to this entire series of videos (but especially the immune system ones!!) I took the MCAT last May after many months of studying and watching this series over and over and over (by the end I was literally playing them while I slept). I got an amazing score and I've now been accepted to a couple of great schools, and I literally could not have done it without these fantastic videos that present the topics in such an engaging and informative way! Seriously, THANK YOU!

[@NotagYmra]

The Macrophages are so darn cute!!

[@misss7096]

And the neutrophils! ☺️

[@JoseJimenez-sh1yi]

Best waifu

[@katiie7]

My first thought ☺️

[@HeIsAnAli]

Careful, they're only 17. _(Oi, oi!)_

[@belgiumball2308]

Macrophage: WE ARE INFECTED WIH THE EBOLA VIRUS MA' AM CD4+ CELL: THEN GET TO WORK YOU FREAKING @#$%@$$#$

[@herpsenderpsen]

this is the best animation yet, oh my god.

[@Thought-Cafe]

+herpsenderpsen Thank you!

[@Chaltaq]

+Thought Café Your every animation is amazing :) Do you have a store we could buy products from?

[@sydney3213]

+

[@Naveahnikole]

*you just explained 2 chapters of college micro in like 5 minutes*

[@ronb7062]

yes. haha.

[@scabootie]

but you learnt f'all

[@davidcrawford4909]

Its 9

[@aloksrivastava7483]

3:13 BAD BAD BAD.BAD!!! I AM NOT REALLY GONNA BEACOME A COOK

[@keraris1639]

Ave Hank!

[@Grain172]

I work in medicine and i approve of this video, everything is spot on, amazing presentation and an absolutely hilarious barrage of jokes and puns. Well done Hank, well done. I will be referring to this video anytime a friend of mine asks about immune systems in the future.

[@roisin9401]

hes gesturing so hard the fluid on the table in the flask is jiggling wildly

[@averi_qq]

I don't know why people hit the dislike button... your videos are amazing keep doing what you are doing

[@hamzaalali114]

I think because he is really fast in talking

[@thejoeare15]

Well you can slow down the video...

[@K5E4VX7YY2I9N]

The dislikes are viruses that escaped the immune system.

[@ccmkoho]

Jose Arellano , yup at 75% he sounds normal

[@yarakharam5343]

Simplified bait video, useless graphics (but good, gotta give em that!), narration is "overacted" to the fullest.

[@kimscandles]

I can't explain just how much your videos are helping me! I'm also 62 but just getting into this education lark (I hated school when I was a kid, now I'm a big kid I don't think I'll ever really grow up) If only this sort of thing was available then! I am training yes at a late stage to be a reflexologist and need to understand anatomy and physiology you have made this all possible as I was struggling just reading books. Thank you, thank you, thank you.

[@rain.enthusiast]

I need plushies of those little animated cells omg

[@paytonvandy8140]

Same! They're the cutest microscopic structures I've ever seen

[@quintenfranks8024]

+Jess Liu I want the plague doctor NK cell

[@mythologiefan]

they kinda exist already. check giant microbes. There are several blood cells too.

[@plankton67js]

+Jess Liu Indeed :)

[@DinzoArchonic]

+Jess Liu I remember that there is a company that makes custom plushie toys. I forget the name but you can look them up and send them this video saying you want a plushie of this cell at this time in the video.

[@John-ih7gp]

The professionalism of this channel is incredible. So informative and yet even I can almost understand what's going on.

[@wavyjr6600]

Whos here after the coronavirus outbreak

[@dalandan1992]

Better be ready

[@pikaszablak7933]

That and after watching Cell at Work.

[@chandlerancar1080]

Im here because of cells at work also.

[@edmind47]

Children:*sighs of relief*

[@thebelyahvlog7059]

me

[@sierralobo7163]

For some reason, I lost it when the Hypothalamus used Fire Blast. XD I love this unit.

[@tuke3541]

Legend27?

[@MistressVantablack]

lol same

[@midnight_gmr8562]

It's not very effective...

[@lukaswalker7230]

@@midnight_gmr8562 haha

[@olivia2172]

I can't tell you how helpful this episode has been to me. I have an immune system quiz a couple days from now and being the visual learner that I am, decided to watch this episode in order to better understand the process. My Biology AP grade and I thank you for your thorough explanations and great analogies and examples.

[@jatvirginmega]

"and it can do it over and over again, like a boss" OMG

[@ctrooster4536]

I didn't know bananas came from factories so glad I learnt something from this vid

[@kynansmusic9724]

our own immune systems are more intelligent and work harder than most humans do...

[@shaunowyang2841]

lol very true

[@alejandrovallejos4454]

but actually your immune cells are human too.... pero en realidad tus células inmunes son humanas también... xd

[@izjerker]

Your scope of domain gets larger.

[@IvanMatyushov]

but if it's a part of us along with many other organ systems then doesn't that mean that humans actually work far harder than the immune system itself?

[@Cheka__]

I wish my I.S. would go to work for my brain cells. They're doing the jobs that Americans just don't want to do.

[@nstrisower]

"You can also call them NK cells, but, like, why would you do that?" > **calls them NK cells**

[@annaotto7256]

“The pathogens are flooding in like orcs from helms deep” that had me dying 😂

[@theresageiger584]

Are you better

[@flyingzambie1201]

NEXT TIME ON IMMUNEBALL-Z

[@K_i_t_t_y84]

+ling Su LOL!

[@MosesPaulShelest]

+ling Su This has to become a thing!

[@flyingzambie1201]

What will dendritic cells do with an overwhelming attack on the body? TUNE IN Next time, for "THE ADAPTATION". PS. the mitochondria is the powerhouse of the cell

[@ferret813]

+ling Su lmaoo gold

[@洪堇芝]

+Paul Ferrell MBC播.M（沒開口） 沒 :😶😀😑😀😐😉😀 😃

[@m26pershing67]

neutrophils: we can destroy bacteria ! macrophages and monocytes: hold my proteins

[@therightflyer7806]

yeet

[@MrF3legendary]

As a struggling A-Level Biology student, thank you Hank Green and the Crash Course team, you rock!

[@royslanguage]

Never saw a more interesting biology video.

[@Nekotamer]

those macrophages are absolutely adorable, i would buy a plushie.

[@anumitsaralkar9979]

They've really outdone themselves this time, haven't they? Thoroughly enjoyed it. Good work CrashCourse team!!!

[@FrumpybutSuperSmart]

AAAAHHHGG CLIFFHANGERS!

[@matiaselizalde7051]

+Caer Ibormeith Game of Thrones style D:!

[@RBLXbranefreez]

+Caer Ibormeith You have to admit, though, that this particular cliffhanger was quite masterfully presented.

[@Itaju]

+Caer Ibormeith spoiler alert: watch Crash Course Biology #32: Immune System

[@saomaitran65]

Itaju pp

[@chattapolchawantanpipat9156]

Yep IKR

[@marypusineri6291]

OUR BODY WILL BUILD A WALL (Skin), AND BACTERIA WILL PAY FOR IT 2:20

[@WadcaWymiaru]

Mexicans = germs? I was thought it is only about germans XD

[@elenorcorano5014]

I love the Pokemon reference 😁

[@midshitfuta]

When?

[@mistersquirtlegamingandtut5936]

Musent! Hey other me!

[@mistersquirtlegamingandtut5936]

Btw it's the fire blast

[@zoroearc2582]

But Fire Blast used the sound effect for hyper beam

[@ainsoff_6663]

Totally! I keep rewatching 😂

[@avi8aviate]

"Just because it's simple doesn't mean it can't be elegant." A perfect example of that would be Kirby.

[@GervJean]

DO MICROBIOLOGY!

[@0123biteme]

PLEASEEEEEE

[@chloroplast8611]

THIS IS MICROBIOLOGY!!!!!! YOU JUST DONT NOTICE YOU ARE LEARNING YET

[@douglasw1545]

And kinesiology!

[@chloroplast8611]

This is letterally the same things as a chapter in my microbiology textbook

[@SkopeeProductions]

Yup, I'm watching the immune system series for my Microbiology final!

[@Akira_1008]

Gotta love learning about the immune system while in self isolation from a spreading virus

[@jtech87]

Amazing episode. Very funny and very informative.

[@elsamado2260]

I love this guys. I am watching a video that I don't need to watch just because it's very well made !

[@Michele8340]

Just happens I'm doing this in biology, my absolute favourite topic when it come to biology, so grateful to be able to watch these videos to enforce everything i learned in class(while teaching me more) thanks again!

[@akashalihazarika4690]

I actually found the CrashCourse Biology version of the Immune System more helpful although the animations are better here yet it was more easy to comprehense in that video. Is it just me or anyone else too?

[@inkedseahear]

so basically the immune system is the custom and border protection, your Innate is the office of border patrol, adaptive defense system is the Office of Field Operations

[@anmolsaini3388]

Whoever did the animations needs a pay raise

[@Silverpickaxe15]

Don't get me STARTED on the dangers of bagel cutting!

[@aarushigrover6674]

Coolest Nerd Eva! Who all agree?!?!?!?!

[@lachlanmc2335]

I DO

[@akashalihazarika4690]

@Aarushi Grover Are you a forensic student ?

[@sharanski]

What I learned: PHAGOCYTES ARE BADASS!

[@katiedickerson134]

I was in tears trying to learn this the other day, but this video helped so much!

[@Master_Therion]

"Natural Killer Cells" would make a great Quentin Tarantino film.

[@BosonCollider]

Natural Killer cells are basically like the inquisition. Because you didn't expect that comparison.

[@Ordoabchao-x9k]

Well they made them ss like soldiers in an anime. That's something

[@enikisser]

hahahaha..

[@themightykyuss]

I'm assuming you already know that he wrote the screenplay to the movie *Natural Born Killers*. Such a great movie.

[@avocadothecat]

no but they made a great anime

[@Filipinoimposter]

This reminds me how amazing the human body is that it can all of this without me thinking about it

[@Kingwut117]

BURN EVERYTHING. Awesome Seriously the immune system is so freaking cool

[@jeanie9350]

these example are insane: "cut myself when opening a bagel" "slipped in a banana factory and grazed my knee"

[@jackiejurgens238]

Amazing job again guys! Just wanted to add that fever also makes it harder for the invading bacteria to replicate as our usual body temperature is their optimum and a lot of bacteria are rather sensitive to temperature changes (at least that's what I learned in my immunology lectures)

[@matthewmcdermott4849]

What a convenient time for my a & p class to go over the immune system

[@EntrE01]

holy crap the epicness of this episode is over 9000!

[@errhka]

Someone had way too much fun making that immune cell battle

[@K_i_t_t_y84]

This was so amazing and interesting and I especially LOVED the "Final Fantasy" style "cell fight" animations!!

[@Thought-Cafe]

+Megan Rivera :-)

[@K_i_t_t_y84]

Thought Café I subscribed to your channel!

[@JDraks]

+Megan Rivera It was Pokemon. Fire Blast is ripped directly from Pokemon.

[@K_i_t_t_y84]

JDraks Final Fantasy came out before pokemon did, Final Fantasy was released in 1987 and Pokemon came out in 1996. And I understood the Fire Blast Pokemon reference but the fight was in the style of Final Fantasy. I've been a video game geek for 31 years, you don't have to question my knowledge.

[@JDraks]

Megan Rivera The health bars and text box at the bottom are pretty much perfect matches for Pokemon. Really, the only difference between this and Pokemon is that Pokemon text boxes would be on bottom right for left and top left for right.

[@SogMosee]

Anytime I hear about all the awesome ways my body is protecting myself from the outside world-which I hear mostly from you and Kurtzgesat-I get all giggity inside. Like, my body is freaking awesome! Good job bod!

[@marlenehill8835]

Man!!! I can't say enough how awesome!! you are... I got an A on my bio.... I love you!!! ;-))))thank you very much!!

[@Kit91180]

If there was a macrophage plushie I would so buy it! They are so cute!

[@lougert]

Soooo... My biology final was this morning. And my professor specializes in the immune system. Thanks for nothing, Crash Course. But seriously, I actually appreciated these videos a lot while studying for this class. They made it a lot more interesting and manageable.

[@nicktk1]

+Kelsey Gertje May the curve be in your favor

[@lougert]

Funny you say that... my professor also doesn't curve.....

[@nicktk1]

:

[@Syverson1979]

Shut up, average person.

[@nicktk1]

+Syverson1979 okay then....

[@kiwi7676]

"The pathogens are just flooding in like orcs through Helm's Deep". Best lotr reference ever!!!! hahah he's so awesome :)

[@cuddles-ns6cz]

Why are all these white blood cells the most adorable things I have ever seen?? Oh my gosh, they are so cute!

[@LucyGem98]

The cells are so cute

[@janellacruz8124]

"You can also call them NK, but I mean, why would you?" Hahaha. Hank, cracks me up!

[@SkopeeProductions]

"Banana factories are very dirty places!" That's the quote that got me from this video :D

[@spartanhead8131]

@@SkopeeProductions Wounderful quote! Wasn't it?

[@VidaenEquilibrio369]

Maravilloso, Muchas gracias, explicacion clara, fluida y muy amena. Fue mi primer video, continuare viendo todas las series.

[@christinekangaslampi1425]

Best episode ever? Can't wait for part 2.

[@wintersong6107]

this is the cutest video on immune system EVER!

[@abdullahwaseem9895]

can you please do a detailed video on IBS i.e Irritable Bowel Syndrome . How it effects the body and any prevention ways.

[@sarahtelford9601]

Abdullah Waseem omg yes

[@somedrylad8338]

WBC appreciation week, be grateful of your WBC officers

[@castrelspirit]

nah fam, long live bacteria

[@jeanlanz2344]

The immune system videos are among the best in the whole A & P series. Phagocytes and natural killer cells are described and illustrated in such a clear way. Thank you and God bless.

[@spaghettitastesgood]

I have test soon for immune system and i was so bored... However after watching this, it made it fun to learn!

[@bluebrightstar1117]

"your outer fortress has been breached, and the pathogens are just flooding in like orcs through helm's deep" I love you 😂❤

[@ana-zu3gn]

you know what ,I´m tired of whatching all you videos at school ,but ,they really help me to do homework

[@fatherdoctor]

If everything fails... BURN EVERYTHING :D

[@adamlatosinski5475]

+fatherdoctor "Burn them all" - Aerys II Targaryen

[@creepernerd101]

That's called cytokinesis xD

[@ConradJD777]

+fatherdoctor IMMA FIRN' MA LAZER!!! BBWWAAAAAAA!!!!!!

[@abikochin2462]

+Conrad JD 777 i love your minecraft skin xD

[@ConradJD777]

gamer mega elite Thanks m8! ;)

[@candisgoins6306]

wow that was the best description of the immune system i've came across yet. So cool! thank you so much

[@Siberianwolf232]

1 2 3 4, we are Cells at Work!

[@Chris14_]

?

[@emmanuelbenitez3049]

Ahhh, I see, a man of cultural

[@Tiemsz]

This channel has saved my life so many times, thank the freaking lord for this channel.

[@jean-paulfornes8301]

At minute 4:58 its not exactly true, MHC1 is presented on the cell that are infected by a virus, cancel cells etc, its not true that all the cell have MHC1, but whatever, i love your videos

[@sir.sithis7619]

Awesome animation and video, I wish my teachers used Pokémon animations to teach me about the human body or anything. Your probably ones the best tutor of the 21st century.

[@Humster]

I totally lost it, during the Monocyte evolving + 6bit music

[@anber4129]

😂😂

[@iloveamerica1966]

On one hand, brilliantly silly and entertaining, and on the other nicely comprehensive. Good video.

[@cuthon3574]

4:30 macrophages "LIKE A BOSS"

[@gina5908]

These Immune system videos have helped me pass my Biology final exam. YES!!

[@TaiChiKnees]

I gave a lecture on antihistamines and inflammation just last week... next semester I'm using this video instead. The animations were amazing! PS: Rubor, tumor, calor and dolor. Oh yeah, you know what I'm talking about...

[@christinevakas92]

Thank you - I learnt heaps, will remember it with the help of your visuals and have lots of laughs. Who knew science could be so funny...

[@tensequel7818]

aren't those the cutest cell you ever seen?

[@mauriciomesa6455]

You really cheered up our neurons to better understand this subject and laugh at the same time.

[@stallben]

I know they're protecting me, but I feel sorry for the bacteria at 3:36. WHY DO YOU HAVE TO EAT SOMETHING SO ADORABLE?!?!

[@naveenreddyadmala3669]

These videos are amazing....... you have to make more of them

[@AndyG94]

Cells at Work!

[@doumahamigahila8133]

how perfect and amazing the human body is

[@Steve-xq6ps]

Really cool animation, at 6:30 thou that battle theme makes it even more interesting

[@Sparkdivineharmony]

Hey crashcourse have you guys ever considered making an educational animated series for kids. My daughter is 4. Sometimes when I am using your videos to brush up on a topic, she's intrigued by the animations. She then asks me a ton of questions but that's great because she learns a lot. lolol anyways love your videos!!!

[@jakemauger8377]

Now I can't stop imagining white blood cells sounding like Link from OoT. Thanks, ThoughtBubble.

[@angeldude101]

+Jake Mauger Hyah!!!!!!!!!!!!!!

[@Thought-Cafe]

+Jake Mauger ;-)

[@JDraks]

+Jake Mauger HYAHHH!!

[@plankton67js]

+Thought Café Sweet Job xD

[@nelo4real]

I am in awe of how much God loves us, even down to the cells he put in our bodies to protect us. What an awesome God!!!!!

[@darrenanimatic9675]

They protecc They atacc But most importantly We want our body bacc

[@memegraveyard1]

Um, um, um, uh, uh, hehe

[@allanwells8756]

I’m laughing because u thought u were funny

[@brittsgebruikersnaam]

I have to learn this for my biologic PSYCHOLOGY course, I don't know why... But CrashCourse is my savior.