The Nervous System, Part 3 - Synapses!: Crash Course Anatomy & Physiology #10

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When I am older and no longer poor I am going to donate to CrashCourse on the regular, this is such an amazing resource and I want to support that

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Good for you.

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Any dollar counts. Don’t wait till later, most people procrastinate time passes and look back 20 years have passed. Do it now. God bless.

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@@redstonebear7_342 4

[@GreenOrangeOxygen]

"Take cocane, for example. Don't take cocaine." This cracks me every time

[@DuranmanX]

GreenOrangeOxygen Don't take crack

[@kefkapalazzo1]

***** don't take heroin or meth. most other things are good to try just once though

[@videotrash]

kefkapalazzo1 like ketamine, pcp or angel's trumpets? kids, don't listen to this

[@kefkapalazzo1]

im not saying they're good to take, I'm just saying at least they aren't like heroin which no one takes just once. you can try most drugs one night, have a great time or a horrible one, and you can still walk away from it.

[@videotrash]

kefkapalazzo1 yeah, i get that and my above comment wasn't meant to come across as really serious. i think it's just worth pointing out that there are many drugs besides the few you mentioned that can be massively harmful or lethal upon first consumption,though some may be not all that well known.

[@kheatthr1892]

It’s 7am, my test is at 10am I am literally crying, real tears. I’ve been studying this for weeks and been confused for weeks. You just took everything I thought I knew and made it all make sense

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Good luck on your test, stranger.

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I love that he talks fast. I can quickly take in much more information and he keeps me from getting bored.

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Plus you can rewind as much as you want !

[@yalnayal]

and they have captions

[@cscmcscm2513]

I also hhhhh

[@danielmuresan6779]

you know, ugh... you can speed up the slow talkers...

[@B큥-p9z]

@@danielmuresan6779 and, .... slow down the fast talkers... :)

[@anamikajoshi-0826]

This was really really helpful. P.S. the neurotransmiters were too cute.

[@sirenia1241]

Anamika Joshi I agree

[@shao2959]

agreed. With both statements

[@holli_bells7048]

Anamika Joshi little late, but I have mine tomorrow 😂

[@bananiesricsiriccs]

If only high school teachers would be that exciting, and enthusiastic about the topic they teach...

[@RieMUisthegoaT]

ikr, my teacher explained things perfectly but he was like: "blah blah Ca+ goes here Na go here understand? good"

[@christophersymons8667]

High school teachers don't get the luxury of doing a lecture when they feel psyched up, doing retakes or cuts to keep the action moving, or any of that movie magic. They get one shot at a great performance.

[@CJ-yz6he]

My teachers aren’t great at connecting to students except for my science teacher. she is like him😃😃😃

[@benutzeraccount5127]

Sarcastically enthusiastic.

[@Sup3rD4ve]

It's hard to maintain your enthusiasm every day for decades when half your audience is only in the room because they're legally required to be in school every day, and would rather experience physical pain than listen to you speak one more sentence about neurotransmitters. All that indifference (or outright malice) can wear down one's enthusiasm for teaching very quickly.

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I used to hate these videos back in high school because my teacher used to show these instead of slowly introducing and teaching the topic, which made every student feel overwhelmed and stressed. Now that I’m in college, these are so great for reviewing material because they go super in-depth and explain things very well! Great work!

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I realize most people would have trouble understanding due to how fast he is talking, but oh my god. As someone Hard of Hearing, it makes me SO SO SO SO SO happy to see that there are captions. They were incredibly helpful, there's almost never captions in the videos my teachers show their classes. Thank you so much.

[@jpkelley2]

this helped me more then my professor did

[@thomasfarrish8053]

than* Your English professor failed you.

[@lazers28]

this reminded me of an astronomy professor that used to say, "if you look at the sun, don't look at the sun"

[@bunji9234]

Takes teachers at my school 2-4 hours to teach this.....and we get bored...you did it in 10 mins and I loved every second...you guys help so many people through exams so please please don't stop doing what you're doing. Thank you so much x

[@BobTheVeteran]

When you're crash coursing on CrashCourse 1.5 hours until your mid term. Thank you sooooo much for all the effort you put into making these videos. They're the BEST review out there for students!

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I am a nursing student and you have helped me understand how the body works so well. Thank you for making such awesome videos

[@sirenia1241]

Noah Brown I am taking nursing during fall.

[@hamptonjoslynjh]

I'm a pre-nursing student in anatomy 1. I use to hate his videos because he talk so fast but now I can slow down his videos so I definitely understand what he is saying. He is not boring with his videos and the video animation help with visualization of the concept. Well I'm hoping part 1-3 helps me on my exam Monday because my professor don't nor do his study guides 😂😂.

[@mjskyshep]

You know Hank does a good job of explaining when your Biology professor in COLLEGE tells you to watch his videos.

[@N00RA96]

I have my final Psychology exam tomorrow. This counts as studying.

[@rokas8006]

How did it go?

[@anitacrumbly]

Two years later but same lol

[@M7mdx3zz]

Lol, same here

[@bara9880]

mine is in 20 days lol

[@sydneyturnbull7760]

I feel you. I have my bio exam tomorrow...

[@MsFlorence100]

Take cocaine for example **DON'T TAKE COCAINE**

[@yalnayal]

ikr xd

[@anamikajoshi-0826]

Lol

[@HerNameWasFloriel]

+

[@karamveer2472]

+Anamika Joshi ru Indian

[@sarasalah4745]

Flora Jathanna 😂😂😂😂😂

[@malharnagori5221]

Man that analogy is amazing!

[@crashcourse]

malhar nagori Right? Some of the less science-oriented minds behind the scenes were a little blown away by how effective that analogy is at communicating the general idea. We love our writing team! -Nicole

[@yasminakatebi9265]

+Anti Bacterial Hand Sanitizer why?was it bad?

[@breadvelvet]

+Mizan Rahman the anal helped me understand dopamine at an intimate level thank you!

[@Quixotic1018]

Sex = "really, really great doughnut".... Science!

[@esteban578]

I love you crash courses. I've spent hours watching you videos

[@chels5174]

These videos are the reason I am passing my anatomy class

[@Disrobingkitty]

+Chelsea B Wish I would've found this sooner lol the semester is over next week >.

[@JordanEromonsele]

+Disrobingkitty right!?

[@Disrobingkitty]

lol

[@shelikestuff]

Chelsea Barrios same girl , same

[@merryissac8265]

For the first time I felt like I learned something for REAL! Amazing teaching and even more amazing graphics. Was very helpful. Thank you.

[@Exotixa]

That Neuron's face was so darn cute >_

[@brendarodrigues3046]

BIG Thanks for this crash course on synapses and neurotransmitters. The information is so easy to retain in the matter in which it is delivered. You're doing an awesome job relaying this data! These brief classes give an entire new outlook on science and its major role in life. Thanks B

[@emmagreen9022]

can you come be the biology teacher at my uni? Lol, i learn more in the 10-15min videos then i do in 2hr lectures

[@marloesnoordermeer2646]

Hahaha i love the part where Hank says:" take cocaine for example.. don't take cocaine"

[@ArkireOfficial]

If you have the necessary time and resources, it would be a great idea to make crash courses about neuroscience or neuroanatomy :) I think a lot of people would enjoy it!

[@jess5678g]

Aaaaaaand my A&P final is a go. Hank, your videos saved my life and my exam grade.

[@okoyeemmanuel4481]

i love this guy .... Simple short and precise ..

[@MockVision1]

My physiology professor is sooooo smart and has a way of explaining simple concepts with really annoying science jargon and beats around the bush, resulting in mass confusion. I am so happy these videos exist. it took her 3 hours today to explain this btw....

[@VelinSevven]

This video's great! We watched it in my psychology class and it really helps to better understand the Biological Level of Analysis.

[@hasini]

This basically summed up an entire chapter in my bio book, thanks! Also, Hank talks unbelievably fast. I'm sitting here still processing the texting analogy and he's talking about not taking cocaine :')

[@M.M.Y.B]

"Take cocaine for example, don't take cocaine"

[@ilmytabby]

+Mol Berry lol

[@boulder50psn86]

y u say dat

[@queensaharaice7376]

Lol ikr!? Crash Course is amazing!

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Well it's logic

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I love the crash course anatomy & physiology series! This is beautiful work.

[@michaeldoyle7714]

Just thought I’d throw I my two cents in and say, “you guys do one hell of Good job, putting this whole thing together”. ThankYou.

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Mmm . . . maple bacon doughnut. My Canadianess approves.

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Murica f*ck yeh

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welcome to America

[@michaelarae20]

I have a neurophysiology exam tomorrow, this set of episodes really helped reinforce the information I'm being tested on. Bravo 👏🏻

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My whole semester in a couple of videos... lol

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This Channel is A Life Save All i Can say is "THANK YOU SO SO MUCH"!!!!

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This is awesome!!!! I'm in college studying the fundamentals of the nervous system and this is helping me immensely in grasping a lot of the concepts. I wish I could download these videos.

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"...everyone just got maxed out and exhausted and turned off their phones for good...which would be death." If this isn't today's techno-savvy generation in a nutshell, I don't know what is. XD

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'Half a Heartbeat' welp found a perfect song title.

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Hey guys? Is there any way that you could do a religious studies course please? I understand if this couldn't happen due to insane comments and flamewars, but even a mini series would be fantastic. I just really want an unbiased, objective course on the major religions, beliefs, practices, etc. It's difficult to find info on this without being crushed with bias. Thank you so much, I love you guys!

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Sydney Hall this^^ CrashCourse

[@kevinclass2010]

Unbiased religious studies? I just wander how people would react to the facts?

[@Bobsry16]

Kevin Lopez Unbiased doesn't mean atheist or anti religious. It means unbiased.

[@kevinclass2010]

bob dash I never meant John Greene was going to lecture "there is no God", but rather about inconvenient facts, such as, the poor historicity of Moses and the Exodus, the tablets of ugarit in Syria, the pagan origins of Judaism, the pagan elements in Christianity (Christmas and Easter), and the council of nicea. I just was saying that an unbiased review of the religions will be greatly inconvenient for the religions themselves

[@Bobsry16]

Kevin Lopez OK, i see what you mean and i agree to some extent. There are a lot of double standards and inconsistencies in modern Christianity, Islam and Judaism. Those are the religions that tend to go crazy when someone contradicts there canon, regardless of accuracy or basic human morality. This criticism is coming from a open minded Christian. The pagan thing is the one of the most ignored issues in major monotheistic religions.

[@Carol1012u]

this great review for my midterm!!! thank you so much for these videos truly a grade saver!

[@wesjales5578]

Fuck, I wish these videos where in my class room when I was in high school.

[@rikkifrank5681]

Thank god for your channel, you guys are god sent. literally helping millions of students pass their classes half a decade later

[@HarryPotterFreakLena]

This was one of my favorite parts of studying biology in high school. I always found it fascinating and graduated high school with the topic of how the brain works for my AP class

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Watched all 3 videos! So ready to ace this HAP test! Thank you crash course!

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Works as entertainment, and helps with your exams! This is how to not get bored while studying.

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You are the only reason I got an A+ in A&P, thank you Hank!!

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Thank you to everyone who made crash course possible !

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ty for completely covering what i learned in 6 hours worth of classes at college in three 10 minute videos

[@SidCurry]

Hank (and CrashCourse), it's thanks to you that I became motivated and started making my own videos (in fact, I uploaded my first videos only last week!) in the hopes that I can help more people aspire to look at the world through a Scientific perspective. And if anyone here is interested in watching other science-based videos, please give my channel a try! I strive to make my videos as visually appealing as possible, and as a grad student who is trying to put himself through school while also supporting his parents, your support and viewership would be much appreciated! Thank you guys :D

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i like the intros on your vids haha

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You again 😀😀😀😀 i see good potential in you

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Hey ScienceSid I like your videos! I'm doing the same thing and maybe you can even take a look at my channel as well!

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ScienceSid Are you Sid the Science Kid?

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ScienceSid sorry for 2 years late but i'll give it a try

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Thank you!! I've studied this process in 2 separate courses and it never made sense to me until now. Thank you, thank you, THANK YOU!!

[@parodyperson180]

I'm doing revision for my GCSE's in 2 months and biology is one of the first exams: this is extremely useful, Hank :D

[@kousalyaravinuthala298]

We have biomedical signal processing in our engineering. Your videos have helped me to get a clear understanding of the subject. Your videos are very helpful. Thanks a lot!!

[@Sabry1994JeJB]

THANK YOU THANK YOU THANK YOU!! this video was so helpful!! When I first started the nervous system, I wanted to throw my books out the window, but these videos are awesome!! I now understand everything! THANK YOU!

[@griseldachavez3604]

"Take cocaine for example...Don't take cocaine"...Love the little humor here and there.

[@1ERock31]

Take cocaine for example, no, don't take cocaine!

[@yalnayal]

legal rights go to Hank xD oops

[@MochiArtHound]

I'm trying to make a magic system for a story I'm writing that is based on neuroscience. These videos are so helpful. Thank you

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Literally studying for university physiology, thank you for these videos

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i love how they don't put any ads

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Excellent job crash course team! I've never seen neural processes described so effectively and succinctly. Love your videos! Keep making the world more awesome!

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Thought it was too fast at first...but loving it now.

[@Mr_ToR]

1:32 cool reference to 'Fear and Loathing in Las Vegas (1998)'

[@leoshort7457]

Yeah, does Jonny Depp get any better?

[@StevePlaysBanjo]

That banjo playing dopamine molecule is the high point of this series! ❤️

[@dennisa.8804]

"take cocaine for example"..."dont take cocaine" lol no pun-intended, best analogy.

[@ememem2952]

If anything is going to get me through doing Higher Biology during lockdown it's this. Also thank you so much Crash Course!!

[@noemyescobar5663]

These videos are so much fun and are just too cute!!! I love love love them!

[@emmavandooren7498]

Thank you so so much!!! I learned way more about the nervous system than I needed to learn for my test, but I have absolutely no regrets. Your videos are absolutely awesome!

[@brookelee9745]

When Hank talks about this kinda stuff i find it hard to believe humans happened and evolved by chance. It makes it so hard to believe we weren't designed in this certain way. I don't mind if people disagree, that's just my thought. I just think we and the universe are just too complex to have happened by chance.

[@meaganmichaelis]

+Brooke Dendiu I totally agree.

[@venetabeqiri5666]

+Brooke Dendiu I disagree. We started off very simple, and BECAUSE things happened by chance we are complex; imagine you are trying to create a robot, but you cannot decide exactly what materials to use and how to make it; everything happens by chance and the way the robot adapts to the environment over billions of years. Surely the robot would become very complex? This is the same for humans.

[@m7mdhussam164]

+Veneta Beqiri dude you've just answered your self lol, so you're giving us an example of what if WE were trying to create a robot and we started very simple then got complex right? That's amazing but hey that simple robot didn't create it self did it? I won't say anymore I hope this question answer you

[@queensaharaice7376]

+Veneta Beqiri I agree. Besides even if we weren't created by chance its more unlikely were were created by a (usu) white man,who's "Perfect",speaks English, Floats in the sky, and lives in a place unlike earth. Sounds more like an alien to me. Just my opinion, I respect all religions. Peace 😃✌

[@brookelee9745]

+Milo curry I don't think God, I'm assuming you're referring to, is a white American man who speaks english but to each their own to speculate :) I mean to me it makes more sense that we were designed than we just fell into place by chance. Humans and life/ existence as a whole is so complex for me, personally, to think it just happened by chance. That's all, not really bringing God or religion into it but i totally respect if you don't agree. Have a good day!

[@nicolaivey7715]

TAKE COCAINE FOR EXAMPLE... don't take cocaine🤣🤣🤣🤣🤣

[@TinkavdHazel]

I really LOVE these videos!! It makes studying so much more fun, and I'm actually enjoying learning. Thank you for being so awesome~~!! :3

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Life saviour every time. Crash course saved me in secondary school, college and now university🤣

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Thank uuuu so much, sir!

[@samshell9442]

These should have more views. SERIOUSLY THANK YOU! Using this as a supplement for my Anatony & Phys class has helped my grades!

[@daniellachopra1827]

How on earth do you fit in 2 hours worth of lecture into 10 mins? 🤯

[@patriciaenglert9341]

awesome 'Fear and Loathing" movie reference !

[@spencer5256]

the cocaine joke is at 8:02 if anyone wants to skip directly to it

[@ae7452]

Ashes2Ashes. that cracked me up... "take cocaine for a second, dont take cocaine"

[@spencer5256]

Rim shot for the crack pun

[@LindyHoppingMidwife]

Not all heroes wear capes. Thank you kind sir (or ma'am).....(or **insert other pronoun type title here**)

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You are awesome! Helping me get through Physical therapy school one video at a time. Thank you so much!

[@monkeypunch313]

Anyone else using crash course videos to relearn concepts for the MCAT? 🙈

[@V4N5H]

Thanks!

[@NoobityBoobity]

Awww you left out cholinesterase-inhibitors. AKA nerve gas, AKA muscle spasm to death, AKA firing of nerves till your body shuts down. Basically a continuous wave of depolariozation. Plus, cholinesterase is an important enzyme that breaks down excess acetylcholine. BUT, the nervous system is huge and I'm sure you could have a crash course that only focuses on the nervous system.

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Thank you for your work to propagate free education! I love your courses! Everything is clear, simply and especially, fun!

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1000 trillion synapes wow and how is that possible

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Solidus327 magic

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L4v31d3m spooky

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Solidus327 baby jesus made it possible

[@theilluminedone7896]

+Morgan Swellz Your guess is as good as mine. Seems awfully well designed and intricate to have been a natural phenomena.

[@freeassange5667]

+Solidus327 the almighty Allah wished it to happen and it was so, please join Islam for 72 free virgins

[@kimberleybrandes1195]

Thank you for being such an incredible teacher. You make sense of the impossible!

[@domcarter2327]

"because you definitely don't want half a heartbeat!"

[@doraandsusie]

Great video! Helped me a lot while studying, especially the animation. Thank you.

[@codynault8705]

So, why don't depression medications like SSRI's have the same long term negative health effects as another reuptake inhibitor like cocaine?

[@Jackpkmn]

You assume they don't...

[@939bb]

Because SSRIs work on inhibiting the uptake of serotonin, not dopamine (the "pleasure" neurotransmitter) which cocaine inhibits the uptake of, there's no "high" from SSRIs that you come to crave. But, as with cocaine, the SSRIs may interfere with the brains natural production of neurotransmitters (serotonin in the case of SSRIs and dopamine in the case of cocaine), so you must taper off them slowly as your brain readjusts.

[@EJAndrews13]

Cody Nault In the very long term they probably would, but they also probably have a different chemical structure so as not to be as effective an inhibitor as cocaine allowing for a more controlled usage. Then there is controlling how much of the drug you take. Generally prescription drugs that alter neurochemistry should be taken at as low a dosage as possible while still being effective in order to stave off the negative health effects for as long as possible.Plus, if you stop taking the drug, or switch to a drug that acts on your brain differently, the specific areas affected buy the first drug will recover, to a point, back towards that brains baseline.This is also why most doctors will have multiple treatment options, like exercise and group therapy, or art therapy. So the drug, hopefully, is a supplement to other treatments.Wow, that went on for a while. Sorry about that, hope it helped : )

[@Shopenhauer2]

4 year antidepressant user here... they do have long term negative effects... Had to quit them at some point. My memory is not what it used to be. I can no longer seem to be able to stay awake at will anymore, I feel emotions with much less intensity now... just to name a few... It's best to search for a more organic solution in my opinion.

[@divicool72]

Shopenhauer2 Are...are you sure thats not a relapse in depression? cos you know you cant just come off antidepressants, you have replace their effect with other coping strategies. (easy to say, hard to do, just something to consider maybe?)

[@yashikamalhotra3101]

Amazing way to study... You clear all the topics Thanks....! 😊😀😃

[@GustavoMazzei]

It would be great if you breath between sentences :)

[@raymorel1971]

Thank you so much for these videos. I watch them as an addition to studying for my biopsych class and they are really helpful.

[@crashcourse]

Pssst... we made flashcards to help you review the content in this episode! Find them on the free Crash Course App! Download it here for Apple Devices: apple.co/3d4eyZo Download it here for Android Devices: bit.ly/2SrDulJ

[@K_ImNoDr]

Love your app 💗

[@accessibleDignity]

So what does it mean when you have an autoimmune disease? I heard from my doctors that my nervous system is stuck in fight or flight mode, so does that mean it's like I'm on cocaine 24/7? Then, why the chronic fatigue if it's supposed to make me feel over-energized?

[@crazsomelizard6507]

I'm in middle school and I'm watching this before we learned anything about the nervous system just so I know everything before everyone else

[@champagnepapillae]

Good for you.

[@JoseJose-sh7fr]

We've got a special snowflake over here.

[@IshanGupta27]

***** same

[@arousedsquirrel2429]

+CrazsomeLizard The reason you provide is fucking dumb as fuck.

[@crazsomelizard6507]

+Aroused Squirrel I get to b teh smartesht won but I'm in 8th grade now so we no learn bout dat no more....

[@zulenacruz7481]

YOU'RE ALL AMAZING. I've learned more from your youtubes than I have from my professors at the Ivy League school I attend.

[@fabiogreco9899]

“Take cocaine...” -Hank Green