CRISPR: Gene editing and beyond

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nature video

nature video

Күн бұрын

Пікірлер: 977
@anndillm
@anndillm 7 жыл бұрын
As a 3D artist, I feel it’s awesome to see these types of animations being used in education. Keep up the great work!
@paulijung
@paulijung 7 жыл бұрын
Not only the animation is great, but the explanations are the clearest I know of!
@joesharples7224
@joesharples7224 7 жыл бұрын
What software do you think they used to make this animation?
@hesteen55
@hesteen55 7 жыл бұрын
anndillm ;
@xibaryon7628
@xibaryon7628 6 жыл бұрын
Now universities are giving graduate degrees in science communication, teaching them graphic design in order to help explain scientific topics! I was amazed at the animation too! It's so rare to find a video that has great explanation and graphics
@gorannovaks
@gorannovaks 6 жыл бұрын
Joseph, most biomedical animations and animations for commercials production are made in Cinema 4D because of its procedural motion graphics (in c4d it is mograph) package. Also it can be made in Maya 2017-2018, with their motion graphics tool called 'mash'. Besides additional tools are used for rendering (Arnold, Vray etc) and post-production (Photoshop, After Effects). For additional reference or even full models of proteins you can use PDB (protein data bank), all models are free to use; there is addon called mMaya, to install and customize them.
@InfiniteCyclus
@InfiniteCyclus 7 жыл бұрын
As someone who did his graduation in molecular biology I'm in awe. I remember the first time I saw and realised how mechanistic the inner workings of our cells are. Captivating..
@alejandronavarro4128
@alejandronavarro4128 7 жыл бұрын
I feel the same way! It's inspiring and exhilarating isn't it 😍
@alejandronavarro4128
@alejandronavarro4128 7 жыл бұрын
Michael Hurwitz there's the Miller and urey experiment that showed some amino acids could have been generated spontaneously from atmospheric conditions and chemicals present in the early earth atmosphere. Also, you've got molecules (take, RNA) capable of making copies of themselves, while accumulating mutations that makes them susceptible to natural selection. I think that idea is more exciting! Life is.... chemistry and probability. Given the right conditions, and time, it could flourish anywhere. Maybe there's a design... maybe the natural laws of physics in our universe allow this all to happen, and it's pure chance..maybe there's a grand designer who "engineered" the laws of nature to allow life to emerge from nothing. Who knows? The mystery is the most precious part of life... no one knows 😍
@ryanthemainhoee1273
@ryanthemainhoee1273 6 жыл бұрын
According to research,thoughts emerge from neural processes. Humans tend to feel things according to how we perceive information ,so sex has no "feeling" ,science goes deeper than what our brain's process in the 10% that we use. I find it difficult to understand those who say scientific procedures such as hormones can change gender. According to biology,a threadlike structure of nucleic acids and protein found in the nucleus of most living cells, carrying genetic information in the form of genes scientifically determines gender (Chromosomes).Some tend to claim that Crispr DNA can annihilate or mutate chromosomes ,however ,Crispr DNA only binds to the DNA and cuts it, shutting the targeted gene off. The reason why mutating chromosomes or any cell will not be effective is because If you lost a section of DNA in only a single cell or small group of cells, the cells might live as before,and if not they would likely die or be killed due to the deviation. The body has multiple methods of getting rid of problem cells.If the chromosome became misshapen due to the missing DNA, the cellular divison process would break the chromosome and/or cause additional mutations, which would cause one or both cells to die. By stating that , the chromosome that one tried to mutate would only die ,and you would as well due to abnormal occurances and attempts at changing something that scientifically cannot be changed. Many have compared humans to clownfish in such topic as an example,however,in these species, such as many species of coral reef fishes, sex change is a normal anatomical process. . we do not have an anatomical process as they do. Although clownfish can change their physical anatomy , their chromosomes remain as male thoughrought their natural process. -
@sandro3182
@sandro3182 5 жыл бұрын
@@ryanthemainhoee1273 10% use theory is complete fraud, there is no way to calculate percentage of brain, as @Ethan Ferns said, we are using entire brain, some people are smarter, others are dumber. the memory, knowledge portion of brain is anatomically tiny, it is Hypocampus and Amygdala that connects memory to emotions, maybe that's why there is 10% usage theory walking around. On gender changing issue, I completely agree with you, there is no way to change gender by hormones, only way is to replace X to Y or vice versa in all existing cells of person. That's why this thing is called gender dysphoria syndrome, it is psychological problem, like Schizophrenia, Bipolar e.t.c, but of course if you say this in our PC era, you'll be labeled as homophobe e.t.c
@befree939
@befree939 5 жыл бұрын
✋✋
@chimezieosondu7546
@chimezieosondu7546 5 жыл бұрын
This was the most calming academic video I have ever watched
@Dreadandcircuses
@Dreadandcircuses 3 жыл бұрын
Not if you're watching it in 2021.
@LM-gi8hy
@LM-gi8hy 3 жыл бұрын
@@Dreadandcircuses hahahahahahahahaha what a deep say
@RandomnessVortex
@RandomnessVortex 3 жыл бұрын
Yeah
@jasminreyes1278
@jasminreyes1278 2 жыл бұрын
You should check the secret life of gymnosperms, angiosperms. And mosses. Watched them for Botany and they were hilariously great, but also soothing
@cwk9492
@cwk9492 7 жыл бұрын
Great video. I don't have a background in science but I've been following the press on this topic and feel like this is the first clear explanation I've come across.
@mickjagger149
@mickjagger149 7 жыл бұрын
CW C I personally believe this is about to be the next huge thing in medicine. Keep an eye on it because it's truly incredible and has the potential to be an absolute game changer
@krecikowi
@krecikowi 3 жыл бұрын
Millions of years of evolution and scientists think they can make genomes better since they learn how to cut it (not very well). Sure. How much damage those "treatments" can and will introduce to the human genomes... I'm writing this from my perspective, I'm in the field on molecular biology for 20+ years.
@adeelmehmood7439
@adeelmehmood7439 2 жыл бұрын
@@mickjagger149 i suffering polycystic kidney disease by mutations /genetic I keep on eyes and hope if it will bring in our life ameen
@yinosamades8805
@yinosamades8805 5 ай бұрын
Exactly
@alextheafronaut5127
@alextheafronaut5127 3 жыл бұрын
This is very exciting. Sickle Cell Disease, which primarily affects African-Americans, could be cured using the CRISPR system. I lost my sister a couple years ago after her lifelong fight with SCD and the fact that we now have SCD patients in CRISPR trials brings tears to my eyes. I really do love the power of science.
@indiabiologyexplains5013
@indiabiologyexplains5013 2 жыл бұрын
It's amazing right? The CRISPR Cas9 gene editing technique could be used to potentially cure all genetically linked diseases from the fetus!
@fullercrane1795
@fullercrane1795 Жыл бұрын
Science wont sort out the African American issue.
@pointofinterest5981
@pointofinterest5981 Жыл бұрын
​​@@fullercrane1795The only reason why the world is not a better place to live is only because of Adharma. Adharma is our only enemy, Adharma is not any particular person, religion, or race. It lies within ourselves. Adharma includes selfishness, greed, hate etc. Dharma is a notion that shows us the path, it is the concept that says to do what is required of you i.e, do the rightmost thing that needs to be done. You have do it under any circumstances. Do it unattached to the world and everything in it, be it your parents, your emotions, your desires or anything else. It is dharma, a concept, a guiding principle, a conceptualized entity that commands to do what is due to the world, the things that should be done, those things that should be implemented. . By abiding Dharma you always carry out the rightmost action. Adharma is simply not doing the this
@pointofinterest5981
@pointofinterest5981 Жыл бұрын
The only reason why the world is not a better place to live is only because of Adharma. Adharma is our only enemy, Adharma is not any particular person, religion, or race. It lies within ourselves. Dharma is a notion that shows us the path, it is the concept that says to do what is required of you i.e, do the rightmost thing that needs to be done. You have do it under any circumstances. Do it unattached to the world and everything in it, be it your parents, your emotions, your desires or anything else. It is dharma, a concept, a guiding principle, a conceptualized entity that commands to do what is due to the world, the things that should be done, those things that should be implemented. . By abiding Dharma you always carry out the rightmost action. Adharma is simply not doing the this
@spiral2554
@spiral2554 9 ай бұрын
You'll be happy to know they successfully treated it with crispr in 2023
@eladoz-cohen4851
@eladoz-cohen4851 7 жыл бұрын
I truly hope that humanity will fully comprehend the responsibility that comes with using this kind of technology.
@ChristineLoABCBachelorette
@ChristineLoABCBachelorette 6 жыл бұрын
I seriously doubt they will. This is Pandoras box and I do not consent. it must stop. these plus they are also suppressing info on how the technologies generates other mutations.
@augustusjoseph9962
@augustusjoseph9962 6 жыл бұрын
Better they suppress it than freely release information to people that may use it for malicious purposes. All about finding a balance between publishing enough information to keep the public in the loop and staying safe.
@DatManDooley
@DatManDooley 6 жыл бұрын
You guys are idiots! Fuck the mutation! This stuff needs to be researched and if proven safe it can help people with many different types of diseases.
@trendngaming410
@trendngaming410 6 жыл бұрын
DatMan Dooley only problem is when they do find out whatever with this... It'll only be accessible to the rich. But I agree with you
@malvinapushkova2386
@malvinapushkova2386 5 жыл бұрын
This is similar to computer technologies and mobile communication. At first it will be accessible only to the rich. But after a couple of decades to middle class, and more. And this is a technology that can help to prolong life of all people.
@RABBlTFTW88
@RABBlTFTW88 7 жыл бұрын
Wow, I was pleasantly surprised by the high quality of this video. Keep up the great work!!
@jorichardson8099
@jorichardson8099 7 жыл бұрын
Speaking as a molecular biologist, this is a great video. Explains clearly without introducing errors!
@thatyougoon1785
@thatyougoon1785 6 жыл бұрын
As a first year nanobiologist, I do really like the video. It is however wrong on some details, although I think those don't matter too much, considering it is a video for the public. But condensated chromosomes inside the nucleus isn't very accurate, except for if the cell is ready to devide. And all the chromosomes are connected at the middle, also something which isn't always the case. But hey, what do you expect.
@David-iv6je
@David-iv6je Жыл бұрын
@@thatyougoon1785 Simplifying for clarity. Perfect is often the enemy of good, especially with clear presentation.
@fullercrane1795
@fullercrane1795 Жыл бұрын
Really? Do tell. Other then Crispr being something that was discovered in a bacterial immune system. What is it and not for what they say they use it for. What exactly is it?
@David-iv6je
@David-iv6je Жыл бұрын
​@@fullercrane1795 First you use "then" inappropriately, followed by a syntactic jumble. Are you asking a question?
@fullercrane1795
@fullercrane1795 Жыл бұрын
@@David-iv6je Never tagged you. Nor do I care about your high school grade mumbling on about grammar. You're as bad as child saying you didnt capitalize a letter. In fact you're worse. You made that stupid remark because you don't want people to know or ask questions. I see no other reason you be that anal over it.
@David-ey9jg
@David-ey9jg 2 жыл бұрын
This is stunning. The brilliance of the researchers is beyond my comprehension.
@andiarrohnds5163
@andiarrohnds5163 6 жыл бұрын
I am definitely impressed with the accomplishments of our species! Marvelous work!!
@fullercrane1795
@fullercrane1795 Жыл бұрын
Am certainly not impressed with what people have done. Quiet disappointed in humanity as a whole. As science and technology can help many. There's much more foundational problem's with mountains of lies. The way people react when face the true says it all. In fact youtube is perfect example of this. You can say nothing but facts about race and sex things that go on around the world and it will get removed. Making a more psychotic two faced environment.
@tonyprice1786
@tonyprice1786 3 жыл бұрын
Having just read Jennifer Doudna's book "A crack in creation", this sort of video helps bring the science alive. Well done.
@Francisco-j1e
@Francisco-j1e 4 жыл бұрын
Guys am an engineer, but i learned through videos on youtube that dna is inside each cell and chromosomes are just dna incased for when cells divised and there are 23 pairs of chromosomes each from dad and mom and then there complex proteins that copy / zip / edit / crop dna and that rna and other material is inside the cells (but outside the nucleous of the cell) for those dna operations. I dunno what am saying, but am saying, i learned everything today am trying to get a grip and combine all this new info. Biology is amazing, gonna take this serious.
@WarDisciple1
@WarDisciple1 4 жыл бұрын
This makes me wish I understood how interesting bio chemistry can be. I wish i knew this when i was younger. It also makes me think about movies ive watched of advanced xivilazations that have permanently optimized their dna, but end up causing irreversible damage to their species. Which can also be a possibility for us thousands of years from now if we are not careful. Way too interesting of a subject.
@evewurtele1820
@evewurtele1820 2 ай бұрын
perfect for teaching my class. By far the best CRSIPR explanation video I have found, and I have looked at about 20 of them!!!
@clioleo7388
@clioleo7388 5 жыл бұрын
Clear, concise explanation of a difficult topic👍🏼
@KavitaGhosal
@KavitaGhosal 9 ай бұрын
I'm overwhelmed by their mode of action. Splendid animation
@22vx
@22vx 7 жыл бұрын
crispr is bettr than tumblr
@methylators
@methylators 6 жыл бұрын
lol
@oo-gg6yo
@oo-gg6yo 6 жыл бұрын
But tumblr is funnyr than crispr...but you have to admit...crispr is a lot cooler than tumblr
@FrappuccinoAlfredo
@FrappuccinoAlfredo 6 жыл бұрын
tumblr causes cancer, crispr gets rid of it
@AxelZaore
@AxelZaore 5 жыл бұрын
does CRISPR allows porn tho??
@redtails
@redtails 5 жыл бұрын
@@AxelZaore depending on the gene you knock-out/down/in, the mice can probably stay fertile afterwards
@PS-mv7it
@PS-mv7it 11 ай бұрын
Give the animator a raise and a trophy 🏆 that was so well done and thoroughly explained 👏
@sauroros
@sauroros 6 жыл бұрын
The fact that we can visualize such mechanisms is so amazing!
@rock3tcatU233
@rock3tcatU233 3 жыл бұрын
This is the clearest explanation of the CRISPR-Cas9 system I've seen to date.
@havutran2479
@havutran2479 7 жыл бұрын
Such an amazing animation! I am nowhere near biology and genetics (in fact I'm fom AI), and yet I received some intuitive understanding of how this stuff works! These kind of animations can really help people outside the field intuitively understand the topic. Great for general erudition.
@RealStuntPanda
@RealStuntPanda 6 жыл бұрын
You have to define terms! What does CRISPR stand for, what does PAM mean, etc? (CRISPR = *C* lustered *R* egularly *I* nterspaced *S* hort *P* alindromic *R* epeats, PAM = *P* eptidylglycine *A* lpha-amidating *M* onooxygenase, Cas9 = *C* RISPR *as* sociated protein *9* )
@indiabiologyexplains5013
@indiabiologyexplains5013 2 жыл бұрын
In CRISPR cas9, PAM actually stands for(Protospacer Adjacent Motif). It is called this because the sgRNA-Cas9 effector complex uses this three sequence template for site recognition.
@occody
@occody 3 жыл бұрын
The possibilities that Crispr/Cas9 can achieve will be Amazing, spectacular Incredible. We’re at a point where we can unlock our full potential as a species, and what this could bring us (if we use it wisely) I love it
@healingfrequencycenter8542
@healingfrequencycenter8542 5 ай бұрын
lol you have no idea of our potential and they don't want you to know just so you can rely on these artificial means of playing God
@occody
@occody 5 ай бұрын
@@healingfrequencycenter8542 if it can eliminate diseases then why not utilize it?
@occody
@occody 5 ай бұрын
@@healingfrequencycenter8542 You have no idea of our potential either. CRISPR is an interesting concept, and I stand by what I said the fact that it could eliminate diseases as well is proof enough that we should. That being said people would probably use it for something stupid instead of what could actually benefit humankind
@occody
@occody 5 ай бұрын
@@healingfrequencycenter8542 it can cure diseases, that’s potential. What ideas can you offer to progress mankind?
@bootwhip
@bootwhip 2 жыл бұрын
“DharmaCON” is likely the most important thing needed to be known here
@higherresolution4490
@higherresolution4490 4 жыл бұрын
Extraordinary animations! Thank you for this piece. Very interesting.
@harshsinghal4342
@harshsinghal4342 6 жыл бұрын
Best video on CRISPR I have seen so far.
@dinoferrante1718
@dinoferrante1718 4 жыл бұрын
The ease that this can be done should actually terrifying to the human race. Imagine this in the hands of someone with less than good intentions.
@porter2719
@porter2719 3 жыл бұрын
Like Bill Gates and Fauci?
@dinoferrante1718
@dinoferrante1718 3 жыл бұрын
@@porter2719 After everyone has had the opportunity to get the vaccine, I hope they unleash the full force of it by spraying it everywhere. That should rid the nation of a lot of morons like you. I know I plan to spread it as much as possible.
@someguy8273
@someguy8273 3 жыл бұрын
@@dinoferrante1718 are you one of those people with less than good intentions?
@dinoferrante1718
@dinoferrante1718 3 жыл бұрын
@@someguy8273 No. I'm trying to save the human race in spite of the morons.
@someguy8273
@someguy8273 3 жыл бұрын
@@dinoferrante1718 You want to force experimental medical operations on people against their will, despite not knowing their long term effects. But your definately the good guy because you know whats best for mankind.
@olivia_d578
@olivia_d578 6 ай бұрын
This was beautiful and easy to understand! props to the animators
@MGR1900
@MGR1900 6 жыл бұрын
Wow! What a powerful use of animation! That's very impressive!
@oscarprospero-garcia7839
@oscarprospero-garcia7839 2 жыл бұрын
Fantastic animations. Learning is fun with these videoclips. Thanks to all the authors of these great art
@entityshadow8184
@entityshadow8184 4 жыл бұрын
Don't let them fool you, its not about tackling diseases, its about transhumanism and connecting humans with artificial intelligence.
@scottgerloffs6148
@scottgerloffs6148 29 күн бұрын
Its crazy how even the cutting edge of gene editing isn't actually using proteins designed from scratch but merely repurposed proteins already found in nature. The complexity of life is so overwhelming and vast that it almost feels impossible to fully comprehend for our short lived mortal brains, in many cases we are merely genetic plumbers, discovering kinks and fixing leaks but with very little understanding of how to build or maintain an aqueduct or sewage plant.
@thetmntr1943
@thetmntr1943 7 жыл бұрын
watched this yesterday, and i can't understand shit. Now im fuckin stoned, I can even understand the whole universe.
@RandomnessVortex
@RandomnessVortex 3 жыл бұрын
Man…
@RandomnessVortex
@RandomnessVortex 3 жыл бұрын
Dude, the video is way too calming!
@maurorcosta8380
@maurorcosta8380 2 жыл бұрын
O vídeo está perfeito, certamente tornará mais fácil a aprendizagem para os alunos de BIOMOL
@ameeramansour9304
@ameeramansour9304 4 жыл бұрын
شكراً من القلب أفضل شرح شاهدة على الإطلاق 🌹🌹
@warmarmot1
@warmarmot1 3 жыл бұрын
Personally, I'd prefer to keep my natural DNA.
@asterlofts1565
@asterlofts1565 3 жыл бұрын
Ok...
@ooglemoogle8210
@ooglemoogle8210 3 жыл бұрын
its for genetic disorders
@dareks1193
@dareks1193 2 жыл бұрын
@@ooglemoogle8210 for covid also .
@Kojuro-b7r
@Kojuro-b7r 2 ай бұрын
You can get a superpower
@MinxInSinx
@MinxInSinx 2 ай бұрын
​@@dareks1193that is covid 😂🤦‍♂️ You're a host *who brings forth after their kind.. it literally makes bacteria more likely to find the host due to polarity *positive or negative cells even a neutral cell eventually choose sides 🤦‍♂️ It's legal genocide 🤬
@aizekcaballero966
@aizekcaballero966 Ай бұрын
very exciting to know science is evolving to more advance methods that can be used to cure disease 🙏🏼🙏🏼
@22CHARIO
@22CHARIO 6 жыл бұрын
This is a great animation and very understandable thank you for this creation!!!
@allisonz7187
@allisonz7187 2 жыл бұрын
Still absolutely amazing every time I watch it
@elcaballerodelatierra
@elcaballerodelatierra 7 жыл бұрын
Will change everything...
@EE-ie9gm
@EE-ie9gm 3 жыл бұрын
Still waiting
@aurindambakshi1505
@aurindambakshi1505 4 жыл бұрын
Standards still Maintained. No one can replace THE NATURE...really love it❤❤❤❤.
@bestryfulhd2102
@bestryfulhd2102 3 жыл бұрын
the nature is so inttelgent man
@ThePeacesPanda
@ThePeacesPanda 7 жыл бұрын
Great video! It reminds us to look into biological machinery so as to solve our problems! Natural selection is beyond us when it comes to create biological structures!
@NECROMAGICIAN666
@NECROMAGICIAN666 3 жыл бұрын
Reverting nature or die this is all we need
@oreocatsu
@oreocatsu 4 жыл бұрын
I wrote a speech about crispr for biology last year. This is extremely interesting stuff
@Rahul_12345-q
@Rahul_12345-q 3 жыл бұрын
Tribute to Jennifer Doudna and Emmanuelle Charpentier❤️💐✨
@anjuk6255
@anjuk6255 4 жыл бұрын
Please make a video on Cre Lox system. It will be better understood if visualised and help many people. Seeing is believing
@simonchou4597
@simonchou4597 3 жыл бұрын
This animation is awesome! CRISPR-CAS9 system is really interesting! I hope we can utilize more biotechnology tools.
@prateekyadav7679
@prateekyadav7679 4 жыл бұрын
The mind boggles at how far we have come and how much further we are yet to travel. Fascinating.
@healingfrequencycenter8542
@healingfrequencycenter8542 5 ай бұрын
youre going backward not forward if you think this is the way forward
@j.sumeet
@j.sumeet 4 жыл бұрын
Anyone after Nobel Prize in chemistry 2020 ?
@ipsitapanda7245
@ipsitapanda7245 4 жыл бұрын
Meeee
@chandananandeesh6747
@chandananandeesh6747 4 жыл бұрын
Mee
@definitesuccess9872
@definitesuccess9872 4 жыл бұрын
I knew it before the nobel but underestimated its value
@j.sumeet
@j.sumeet 4 жыл бұрын
@whesley hynes i appreciate!
@maart5473
@maart5473 4 жыл бұрын
@whesley hynes you have no idea what you are talking about do you?
@The_Caledonian
@The_Caledonian 3 жыл бұрын
These visuals are much better than the helix, sheets and folders that you're given in text books or shown in presentations.
@julieb9294
@julieb9294 3 жыл бұрын
This method has been applied in covid mRNA vaccines
@rogerbenito595
@rogerbenito595 3 жыл бұрын
Yes to edit and DNA
@olgaustinova8968
@olgaustinova8968 2 жыл бұрын
And killed many people
@indiabiologyexplains5013
@indiabiologyexplains5013 2 жыл бұрын
@@rogerbenito595 and to generate antibodies.
@shigeshi
@shigeshi 3 жыл бұрын
I was just googling this for a paper and now this is in my recommendations. Google works fast 😅
@pretzelschannel6595
@pretzelschannel6595 4 жыл бұрын
Finally, I learned how CRISPR Cas9 works Thank you for helping me
@brianwilliam3341
@brianwilliam3341 Жыл бұрын
We must use these kind of things in a educational level
@EmeLucoH
@EmeLucoH 2 жыл бұрын
I love your work, as a regular citizen and science enthusiast, it´s a perfect way to understand such complex processes
@kmukherjee7
@kmukherjee7 Жыл бұрын
BRAVO, IT IS AN AMAZING ANIMATION OF THE CONCEPT, PLEASE KEEP IT UP...👍🏼
@Gregq96
@Gregq96 6 жыл бұрын
What's this beautiful music?
@diffrent_being8057
@diffrent_being8057 4 жыл бұрын
U simp
@pritichavan7260
@pritichavan7260 2 жыл бұрын
I love to watch science animations ❤️❤️❤️ I love advanced technologies in foreign countries 🙏🌎🙏
@JM-zb8ro
@JM-zb8ro 4 жыл бұрын
This was mind blowing. So much good and bad that can arise from this.
@mehmetberisha3681
@mehmetberisha3681 4 жыл бұрын
This is a great breakthrugh of science.
@JuliusStopforth
@JuliusStopforth 7 жыл бұрын
I would be interested to know how CRISPR/Cas9 differs from current gene editing technology. Is it significantly more effective, precise, quicker than other techniques? Or is it the versitility of the system that is the cause for all the hype?
@vu8944
@vu8944 7 жыл бұрын
Julius Stopforth the sgRNA @0:42 can be designed by researcher to complement with a specific sequence in the genome that researchers want to modify
@innovativegenomicsinstitute
@innovativegenomicsinstitute 7 жыл бұрын
CRISPR-Cas9 essentially *is* current gene editing technology. It's cheaper and faster than previous techniques, though sometimes those tools are still preferable. Generally speaking, what used to take thousands of dollars and months of work can now be accomplished for a few hundred dollars in less than a week.
@tylerpeterson4726
@tylerpeterson4726 7 жыл бұрын
Previous gene editing techniques had to be engineered to exacting specifications. And each edit you wanted to make required the same lengthy process. Now this single protein, cas9, has the ability to latch onto any guide RNA molecule you care to feed it and you get extremely precise activity.
@stardolphin2
@stardolphin2 7 жыл бұрын
Short answer: Yes.
@user-nf5ye4vn7z
@user-nf5ye4vn7z 6 жыл бұрын
Compared to TALENs and random mutagenesis it's better in every way. Random mutagenesis in particular (using UV light/chemicals/transposons to induce random mutations) is VERY time consuming so you'd potentially need 10s of thousands of samples to induce random mutations and identify subsequent gene functions.
@andysux1
@andysux1 7 жыл бұрын
This was a piece of art! Subscribed. Great work
@drucifer00
@drucifer00 5 жыл бұрын
Layman's question. I was born with a genetic flaw that has caused me problems now that I am almost 50 years old. Can CRISPR tech help me?
@lukebraidwood6145
@lukebraidwood6145 5 жыл бұрын
In theory yes, but in reality probably not. Still plenty of problems with off target editing, and delivering it efficiently to your cells. If your problem is with a specific organ or tissue, it's more likely. Crossing my fingers for you
@hammadnasim4518
@hammadnasim4518 4 жыл бұрын
sir, it depends, only a few genetic diseases can be cured by crispr till now, kindly tell what type of genetic flaw are you talking about. it depends on that.
@郑颖-m6p
@郑颖-m6p 4 жыл бұрын
Great video about the application of Crisper! Really inspiring!
@RajinderSingh-tn9pu
@RajinderSingh-tn9pu 7 жыл бұрын
Is there any good text or resources to study more about this topic. If you know then please help?
@somecuriosities
@somecuriosities 7 жыл бұрын
Rajinder Singh Bump. Would also appreciate this.
@innovativegenomicsinstitute
@innovativegenomicsinstitute 7 жыл бұрын
We've compiled a lot of resources (including this one!) on our website - innovativegenomics.org/resources/educational-materials/
@drewthermos3866
@drewthermos3866 7 жыл бұрын
You can play with CRISPr www.the-odin.com/diy-crispr-kit/
@brainstormingsharing1309
@brainstormingsharing1309 3 жыл бұрын
Absolutely well done and definitely keep it up!!! 👍👍👍👍👍
@mellowm5634
@mellowm5634 6 жыл бұрын
tutorial pls i want glow in the dark hair
@bigbananae
@bigbananae 6 жыл бұрын
mellow m your offspring (child) will have the effect not you.
@liljimbob8740
@liljimbob8740 6 жыл бұрын
Bigbanana E hair is dead cells though, is it not?
@sainamahera9413
@sainamahera9413 5 жыл бұрын
@@liljimbob8740 no, it's just protein.
@myrna5277
@myrna5277 5 жыл бұрын
@@liljimbob8740 hair is composed of keratin, the very same protein that is present in dead skin cells
@asmallpanda6766
@asmallpanda6766 5 жыл бұрын
Myr Na interesting. Thank you.
@shama_k2604
@shama_k2604 5 жыл бұрын
My mind is blown by the animation😵😱 thank you so much for making this topic understandable and kudos for your hard work especially Mr. Eric Small and Mr. Elizabeth McDonald🙏🙌
@rakshyapokhrel7244
@rakshyapokhrel7244 4 жыл бұрын
oh my god, i had never seen such a pretty chromosome, these animations are so good
@sillabellasworld2185
@sillabellasworld2185 2 жыл бұрын
Really I hate Science, but when I started to see this types of animation videos I am really fascinating towards Science. Thankyou guys for making learning easy for me.
@Nereus00
@Nereus00 7 жыл бұрын
i wonder how criper does access the DNA sequence when it's in form of euchromatin, packed and covered in histones..
@satyakibiswas930
@satyakibiswas930 7 жыл бұрын
Nereus during replication and transcription DNA unwound from the compact chromosomal conformation, and that's the window when CRISPR works...
@kropotkln
@kropotkln 6 жыл бұрын
In my opinion, it really doesn't matter. In 2018, if you want to alter the human genome, you wouldn't use CRISPR directly on it, it would be much easier to use CRISPR to edit an adenovirus (or similar) vector and then use *that* on the human genome.
@redtails
@redtails 5 жыл бұрын
@@kropotkln ? You get crispr into cells using viruses
@topsycretomega
@topsycretomega 6 жыл бұрын
All of this is so insanely cool
@BlueAsia76
@BlueAsia76 3 жыл бұрын
Who’s here after buying crisper stock 🤣?
@jenroberts7267
@jenroberts7267 3 жыл бұрын
This video is a link added to my i-Text for Cell Biology - incredible!
@whatismynamethisismyname5550
@whatismynamethisismyname5550 6 жыл бұрын
All I see are wads of gum.
@DW-vl2wi
@DW-vl2wi 7 жыл бұрын
Incredible and breath-taking.
@LegalizeAlejandro
@LegalizeAlejandro 7 жыл бұрын
i understood maybe 30% of what I just watched
@SAGAR-ou6ok
@SAGAR-ou6ok 4 жыл бұрын
Superbly done thank you sooo much for this video 🙏
@OGknowbuddy
@OGknowbuddy 3 жыл бұрын
Hmm why is this in my recommended? The Ai algorithm knows what this Rona vaccine is..do you?
@donross7820
@donross7820 5 жыл бұрын
What a gorgeous animation! Thank you
@faith8775
@faith8775 5 жыл бұрын
what is the name of the background music? i really need to know
@aysoum7024
@aysoum7024 2 жыл бұрын
the amount of people who didnt understand the vedio is insane that they are just appreciating the animation rather than CRISPR
@sammypenny4510
@sammypenny4510 3 жыл бұрын
Eugenics?
@unmu1392
@unmu1392 3 жыл бұрын
C-19 vaccines
@prabas8190
@prabas8190 3 жыл бұрын
@@unmu1392 ur mom
@alikhidzam3749
@alikhidzam3749 3 жыл бұрын
Genetics engineering is not bad unless it is only used by the elites
@JJs_playground
@JJs_playground 4 жыл бұрын
Incredible animation. And even more incredible that humans have been able to discover these things and study them and eventually use them.
@thatguyj4834
@thatguyj4834 6 жыл бұрын
NIGHT OF THE LIVING DEAD...
@charanjitjit9297
@charanjitjit9297 Жыл бұрын
Read Robison pathology can't understood!! Watched yours!! Concept Cleared
@mikeumpire698
@mikeumpire698 4 жыл бұрын
Padora's box?
@rasheedthedream7853
@rasheedthedream7853 3 жыл бұрын
This is a great animation! Thank you
@susanraezer1590
@susanraezer1590 7 жыл бұрын
I'd feel better about all this, if I thought they had our best interests at heart.
@VR_Wizard
@VR_Wizard 7 жыл бұрын
They do actually. The use cases are plentiful from better healthcare to increased food production and new materials. I don't think this technology is suited to build weapons with it.
@hotsauce7362
@hotsauce7362 7 жыл бұрын
Susan Raezer: How many times have you done something with their "best interest at heart" and have it totally backfired on you...? Be honest!!!
@ChristineLoABCBachelorette
@ChristineLoABCBachelorette 6 жыл бұрын
you should terrified. China has already opened a human cloning center. They are using crispyr tech to fatten up beagles. did you watch 60 minutes? I did w my parents and they realized the Chinese are doing that to fatten up their food. they eat beagles. do we need to encourage this behavior??? hell no! stop now!
@Litiee
@Litiee 5 жыл бұрын
Very clear explanation and a great demonstration of how it works. thank you very much!
@horsejumpride8423
@horsejumpride8423 3 жыл бұрын
God is amazing and imagine what's in store for you if you are truly saved by the Son of God Jesus Christ who is God the Father.
@glitchmatrix8699
@glitchmatrix8699 3 жыл бұрын
Jesus is the real demon 😈
@dabulls1g
@dabulls1g 4 жыл бұрын
Proud to know my loved one is working on this at Carnegie Mellon University! Super cool stuff. Totally over my head!
@dabulls1g
@dabulls1g 4 жыл бұрын
@whesley hynes maybe you need to watch this video again....or read a book. Get a grip kiddo.
@maart5473
@maart5473 4 жыл бұрын
@whesley hynes Damn Karen. Maybe start educating yourself before you comment stupid things like this.
@dabulls1g
@dabulls1g 4 жыл бұрын
@whesley hynes you’re really convincing me
@dabulls1g
@dabulls1g 4 жыл бұрын
@whesley hynes We should stop hitler, call some organizations for us and get the ball rolling!
@dabulls1g
@dabulls1g 4 жыл бұрын
@whesley hynes yeah, searching for cures to deadly diseases and genetic engineering is totally wicked dude
@carmenmoldoveanu4897
@carmenmoldoveanu4897 3 жыл бұрын
Crazy scientists are playing roulette russe with our lives and think our DNA is some kind of logo play.
@ooglemoogle8210
@ooglemoogle8210 3 жыл бұрын
stupid its for curing genetic defects u idoit
@陈磊-t6b
@陈磊-t6b 3 жыл бұрын
The animation is amazing work!
@RawChristianSuperman
@RawChristianSuperman 3 жыл бұрын
very dangerous stuff
@ooglemoogle8210
@ooglemoogle8210 3 жыл бұрын
how
@tkc3114
@tkc3114 5 жыл бұрын
This has unimaginable potential. Hope to have some benefit from this tech before i pass away.
@Christdeliverme
@Christdeliverme 6 жыл бұрын
You've got to be out of your mind if would think all of these systems are as a result of time+mutation.
@arnavn2554
@arnavn2554 6 жыл бұрын
The CRISPR system evolved in bacteria as a defense mechanism against viruses (so they could target viral DNA sequences and disable them).
@leviaasen
@leviaasen 6 жыл бұрын
So just because we cant explain it all now, a God have to had made it? Just a matter of time before they can explain more
@ripeanuraluca-victoria5414
@ripeanuraluca-victoria5414 5 жыл бұрын
Truly unbelievable...how all these proteins know where and what to do...I know it's chemistry, but still unbelievable
@danmarquez3971
@danmarquez3971 Жыл бұрын
GREAT video!! Inspiring!! Thank you!!
@scottyang1148
@scottyang1148 6 жыл бұрын
Phenomenal animation!
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