CRISPR Revolution: The Future of Genetic Engineering Jennifer Doudna at CNBC Evolve 2021

Biochemist Jennifer Doudna is best known for her pioneering work in CRISPR gene editing, for which she was awarded the 2020 Nobel Prize in chemistry. She’s also a leading biotech entrepreneur, with several life science start-ups under her belt. In a rare interview, Doudna talks about the current work at her Innovative Genomics Institute at the University of California, Berkeley, where scientists are applying genome editing technology to diagnostics, drug discovery, agbiotech and even climate change.
Jennifer Doudna, UC Berkeley Biochemist and Nobel Prize winner, 2020
Interviewed by: Meg Tirrell, CNBC Senior Health & Science Reporter
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[@GDNM502]

Why does CRISPR treatment of Sickle Cell cost $2 million?

[@RJZII]

Need to pay for R&D of the Treatment/Cure, like all medicines. Clinical Trials (R&D) are expensive.

[@chriskatsuras5342]

Jennifer Doudna

[@bikojalal3120]

Is this do anything with Ethylmalonic encephalopathy (EE) ETHE1? Can this disease be treated by CRISPR technology?

[@allknight7905]

How do you get on the list for clinical trials? I want to be on one

[@theylive8256]

Just take the jabs ;)

[@blite13]

boost up ya dummy.

[@PocketRainbow]

@@theylive8256 Moron

[@ManyHeavens42]

When are you going to stop playing God telling us we have to Die and start playing God.give us more life ,Were all Waiting for more life, not Less.Big Bucks

[@Mauriciovideomaker]

She has DNA in On her own name 😮 DouDNA ! 😂

[@brendaorr6064]

You really shouldn't alter the food. Why not inject it into two inches of aloe vera and In jest it in a small swallow of water.

[@theylive8256]

They already injected 6 billion humans with it...

[@magicray5088]

they are changing plants and animals as we speak... some plants are being changed for medicine and they are changing plants for other reasons as well... but they have changed insects like Mosquitoes in Africa , USA in southern States ... Rats on Islands that have issues with Rodents... China Doctor used Cas9 / Crispr to make designer babies... they are 6 to 8 years old now... smart, beautiful and athletic ... I don't know if they put him in jail because it worked or because it did work so well? I don't know but Putin is on record to say he will instruct his people to make super soldiers because he knows the Americans will be doing it as well... AI has said the world is moving so fast that the people can not grasp the speed of change.... I say People we are all old and outdated by what is to come.... Just relax and watch great things change... humans will only get in the way ... I hear your money is know longer needed, New Economy is here, type in New Economy to AI Chat and see what it says? Breath in breath out , let the heavens we dreamed of come to earth... your prayers have been answered ...On Earth like it is in heaven, give us our daily bread.... dream big & allow it to be... NO MORE WARS!!!!! a new paradigm is upon us... Wait... somebody put something in my drink, I am going to go lay down for a minute.

[@anitacason1621]

How do they introduce the editors into the cell? MRNA .... might do it .

[@nickatnick4424]

via vectors like lentivirus (such as HIV-derived ones) or Adeno-associated virus as transport since they infect cells.

[@ManyHeavens42]

All you need is a blacklight and template. Make As many as you want.Where can we get MNM To turn back on Our Cells. Hos Stoping Us now ?

[@ulduzulduz8495]

Ne olur parkinsona bir tedavi bul🙏

[@joeboy7162]

Demonic technique !

[@theylive8256]

It's in the divoc shots! The mark of the beast it's a genetic trait! "Charasso"=Mark=sharpening point!

[@wall57805]

therapy

[@danielmoore4024]

@@wall57805 No, this is disgraceful and evil! Stop disguising eugenics. You're already aborting more black people than white, you already disallow disabled people to be born, more LGBTQIA are aborted than straight, more females are aborted than males, all advertisements of designer babies are images of white males. There's advertisements of anti aging which has nothing to do with sicknesses or diseases, if it was only about sicknesses and diseases you wouldn't of ever thought of touching the human germline. So don't bother denying this is racism, sexism, ableism, communism, eugenics and capitalism. You do not have the right to mess with a person's genes just because you perceive something about them as a "problem". Autism is not a problem, you claim you value all humans equally, since you want to rub us out of existence you clearly do not see us as equal, you are full of discriminatory thoughts like Hitler doing eugenics. The problem is clearly your view of autism and other primarily genetic conditions. I love being autistic, I wouldn't give it up for the world. Molecular biologist Miroslav Radman writes, "Mutagenesis has traditionally been viewed as an unavoidable consequence of imperfections in the process of DNA replication and repair. But if diversity is essential to survival, and if mutagenesis is required to generate such diversity, perhaps mutagenesis has been positively selected for throughout evolution." Do you really want to bring us to extinction? Evelyn Fox Keller explains: "We now know that mechanisms for enduring genetic stability are a product of evolution. Yet a surprising number of mutations in which at least some of these mechanisms are disabled have been found in bacteria living under natural conditions. Why do these mutants persist? Is it possible that they provide some selective advantage to the population as a whole? Might the persistence of some mutator genes in a population enhance the adaptability of that population? Apparently so. New mathematical models of bacterial populations in variable environments confirm that, under such conditions, selection favors the fixation of some mutator alleles and furthermore, that their presence accelerates the pace of evolution." The mutants behind autism and other conditions like Down Syndrome offer some great advantages to the human race, diminishing the genes is a great risk because without those mechanisms there is no asurety of genetic stability pushing us in the direction of extinction. Psychologist Howard Gardner warns: "With the coming of age of genetics, the danger magnifies. Beyond doubt we will discover genes that are important for reading alphabetical scripts; and there is already evidence that a small set of genes may be related to reading problems. As with the brain evidence, such information can be helpful for early intervention; but it could easily be used for stigmatising purposes. Indeed, it might become relevant for marriage prospects, holding a job, securing insurance, or even eugenic purposes. And no doubt, especially in our interventionist society, individuals with a genetic predisposition for reading problems will look into different kinds of genetic engineering or therapy. It is possible that such interventions will work and have no negative side effects, but it is perhaps more likely that they will have unanticipated effects. And we might even want to consider which valued human abilities - eg. spatial or pattern recognition skills - might be placed at risk were we to target our interventions specifically at reading disorders." Do you really want to destroy all alternative perceptions and ways of thinking? Don't you know how many abilities you are going to destroy and how impoverished you are going to make our world because of your cultural myopia? Each time you have tried playing God you have only caused harm. Who caused the climate change? Scientists playing God trying to control nature, did you Gods anticipate the climate change? You are not only messing with humans, this whole earth is interconnected, you are messing with the entire ecosystem, with all life. How many species have been brought to extinction because of humans manipulating nature, there's endangered species today thanks to humans manipulating nature. If we fail to understand and take care of the natural world, it can cause a breakdown of these systems and come back to haunt us in ways we know little about. A critical example is a developing model of infectious disease that shows that most epidemics - AIDS, Ebola, West Nile, SARS, Lyme disease and hundreds more that have occurred over the last several decades - don’t just happen. They are a result of things people do to nature. The diseases you claim you want to cure were caused by doing this, so why are you doing it again? Was the world ready for COVID-19 to strike? I doubt it. World War II was caused by eugenics, why are you following Adolf Hitler's steps? Mutations are not random or accidental, malaria is endemic in Africa and Africans have developed mutations that protect them from malaria through adaptation, Europeans don't have these mutations, if a European goes to Africa they are more likely to get a disease. It was mutations that enabled the Europeans to survive the 14th century bubonic plague. Editing one gene may cure a disease but at the same time make them more susceptible to other diseases. Again, this is wicked and pure evil to think we don't deserve to be born just because we are different. CRISPR-Cas9 is a direct violation of human rights, especially human autonomy. Sort your discriminatory thoughts out and don't you touch us without our consent!

[@wall57805]

@@danielmoore4024 Imaigne comparing cures for cancer to following Adolf Hitler's steps. I understand that your mad as fuck. But save your anger because you will need it

[@danielmoore4024]

@@wall57805 I'm not angry, thanks for providing more evidence for the Double Empathy Problem. How is racism, sexism, ableism, communism, capitalism, only allowing wealthy people cures, health injustice, violations of human rights, commodification of people acceptable? Are You wealthy? If you can't spare thousands of dollars don't expect to be cured from cancer if you ever develop cancer. You didn't invalidate a single thing I shared, all the contradictory evidence against CRISPR-Cas9 and you still want to use it, Jennifer said mutations are random, that was proven falsehood nearly a century ago which is why evolutionary scientists call it the "Randomness Doctrine" as if it's a religious belief, Darwin knew nothing about mutations, that's just blindness wanting to reduce disease resistance and bring humanity to extinction.