Nobel Laureate Jennifer Doudna on FDA Approval of First CRISPR Treatments | Amanpour and Company

More than a decade ago, pioneering biochemist Jennifer Doudna co-invented CRISPR, the gene editing technology which earned her the Nobel Prize in chemistry. Now, the very first treatment based on CRISPR has been approved in the U.K. and the U.S., a landmark decision for the treatment of sickle cell disease and for the potential of this rapidly advancing field. Dr. Doudna joins her biographer, Walter Isaacson, to discuss what the technology could mean for the future - and the danger of its possible misuse.
Originally aired on January 4, 2024
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Amanpour and Company features wide-ranging, in-depth conversations with global thought leaders and cultural influencers on the issues and trends impacting the world each day, from politics, business and technology to arts, science and sports. Christiane Amanpour leads the conversation on global and domestic news from London with contributions by prominent journalists Walter Isaacson, Michel Martin, Alicia Menendez and Hari Sreenivasan from the Tisch WNET Studios at Lincoln Center in New York City.
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[@DonBurke1]

Walter did an excellent job asking relevant and thought-provoking questions, and Ms. Doudna was articulate and informative in her answers. As someone who another form of muscles dystrophy, i anxiously await further developments to make these solutions ubiquitous.

[@annh.8290]

As a grandmother of 2 young grandsons with MD, I am hopeful this could help them.

[@justayoutuber1906]

Wow - what an amazing woman. The interviewer had great questions too.

[@Rebecca0010]

It’s incredible and also too new to know the longterm effects for some time. I hope it saves lives and improves lives. ❤❤❤

[@kathykillgore6440]

This is a wonderful interview. It should maybe, win an award and be viewed by students, for it is packed with info. on a variety of subjects in medicine and gives the average learner a lot of general knowledge!

[@lindas.martin2806]

Fascinating, thanks all involved in the presentation and ongoing work in research, and especially to see that the research is used to be of service for those in need, and protects the public from misuse.

[@dennisreynolds9202]

I wouldn't mind signing up

[@caseyleedom6771]

Thank you for stating the obvious about "Gene-Modified Organisms": that all the food that we eat is already Gene-Modified via traditional Breeding Programs.

[@Bizaaa]

Increíble y fascinante , que más vendrá en el futuro que Jehová Dios nos ayude a entender esta ciencia .😊

[@ilkatrailrunner467]

Fascinating and a wonderful resource for my biology students.

[@atthebijou8209]

meanwhile, our health care stinks.

[@alphaomega8373]

Keep praying, can't hurt and doesn't take any time.

[@justayoutuber1906]

Not for Jeff Bezos and Elon Musk. They can afford it

[@roguemedic]

@@alphaomega8373 Prayer is not action. Voting is the only non-violent way to change this abuse of citizens by their representatives and by the corporations that pay representatives to keep citizens from getting what they need. .

[@robertbrigham1975]

Polycythemia vera treatment?

[@stevechance150]

God bless you Dr. Doudna. R255X

[@nancychace8619]

Excellent discussion. Such a wonderful new tool with positive potential. However, she's right to be careful. Curing disease is a noble endeavor, but there are those who are of significant lack of character who would misuse CRISPR. How do we draw appropriate lines to regulate this wisely? Glad the Chinese are working well with her. A vaccine for Alzheimers ...?

[@denisefuentes7905]

Lawnmower Man. Yayyyyy

[@michaelh.sanders2388]

DEL LYMPHOMA next Please.

[@cilla5277]

How much does it cost?

[@justayoutuber1906]

2 million a treatment for now

[@andrewudstraw]

Regardless of the handwringing, this will be used to edit any part of the human genome and will be a major part of our evolution as a species. It likely will be part of abolishing aging when telomere restoration becomes common. This will be used for germline improvement. You can’t stop it, so get used to the idea.

[@paulheydarian1281]

Slow down. It's only for the ultra-wealthy and will remain that way for decades to come. Most of humanity is still poorly housed and lacks access to clean water and nutritious food.

[@PenelopePitstop888]

Cool, yes, it's our manifest destiny. But the cost is prohibitive.

[@andrewudstraw]

@@PenelopePitstop888 like all new technology, the price will fall

[@chrisfreebairn870]

Sure & what proportion of the 10 billion of us do you think will ever get access to this tech. And, given the technical & ethical issues you've magically removed with your 'pen' for germline application will need to be resolved before any evolutionary drive would be involved, just how soon will this & the numbers affect above, be anything other than a flying car?

[@chrisfreebairn870]

Sure & what proportion of the 10 billion of us do you think will ever get access to this tech. And, given the technical & ethical issues you've magically removed with your 'pen' for germline application will need to be resolved before any evolutionary drive would be involved, just how soon will this & the numbers affect above, be anything other than a flying car?

[@jasonrice1803]

Wasn’t this the beginning of “I am Legend?”

[@louisesamchapman6428]

Spike Proteins

[@garybowler5946]

I'm sure this is great, unfortunately the average US citizen will never be able to afford it. Most private health insurance companies fight us on standard procedures, sad really.

[@davemyers9650]

I like her last name. Doudna?!

[@albin2232]

For optimum health, I recommend that everyone should take an FDA approved broad spectrum food additives supplement. They work best when taken with Mountain Dew.

[@justayoutuber1906]

Of course you know the FDA does not regulate supplements.

[@albin2232]

@@justayoutuber1906 Yes they do. FDA are the biggest supplements manufacturer in the world. They invented Tartrazine.

[@thosethatcan]

Over the counter?

[@matsfreedom]

Safe and effective, I'm sure.

[@AlgoNudger]

So many scitech buzzwords (hypes), nowadays. 🤭

[@lindas.martin2806]

haha, not as many as teens use!

[@justayoutuber1906]

that internet is a fad.....

[@lorenzonewhouse6552]

...as usual funded by the U.S. tax payer , the little guy. A major break through and bingo, extremely expensive!!.............The "market", forces at play, right!??

[@AmyCelento]

It's my understanding the trials being conducted were not (principally) government-funded. You might check the press releases featuring gene editing and gene therapy for the company names.

[@guru47pi]

Prices will come down. The first of anything is always the most expensive bc of enhanced safety, every step being new, lack of scale, etc. Think of the first solar panel. It was so expensive it was only used in space. Now they're millions of times cheaper, and make as much energy as hydroelectric power bc it's the cheapest source of energy in most places.

[@justayoutuber1906]

Where is your proof? Cite sources like a real journaist

[@fppgaming3288]

Soon we'll find out that Trump's DNA has been mixed into us all and we'll all look more like him every day. :P

[@lindas.martin2806]

heaven forbid

[@michaelyoung5707]

When Doudna dreamt of Hitler yet still continued her work, she is God. Human Gods don’t make mistakes.

[@ronkirk5099]

God is a myth dreamed up by humans.

[@michaelyoung5707]

@@ronkirk5099 yup, what are you? An Anunaki SOB? kzbin.info/www/bejne/hX62pGqhjMdnY7csi=z7SmEMMYDa6qJMBm

[@nextinstitute7824]

And Christiane Amanpour used to be the pride and joy of female reporting. Once 😢

[@paulheydarian1281]

She took the road taken too often by many others. She sold herself out for financial security.

[@romanavolny8316]

Humans playing God is very dangerous and can lead to the extinction of humans/plants/animals.

[@edwinmhondera4353]

Food and plants don't need gene fixing

[@justayoutuber1906]

yes they do. I dare you to try to find any fruit or vegetable that has not already been modified.

[@boherupnielsen6355]

Greetings from Denmark. ❤ Todays priests!!! Forgive them, for they know not what they do. Hybris!!! No thank you to GMO food and medicin/ vacsines.

[@justayoutuber1906]

Using the internet also causes cancer. Please protect yourself

[@nextinstitute7824]

To be honest, I can't take this channel seriously anymore considering their biased and tone-deaf reporting on the suffering in Gaza. Skip.

[@MattMobility]

You're silly if you think this clip about a discovery that would transform the lives of people with sickle cell is less important that a bunch of terrorists being pounded in Gaza.

[@Shaolinthemple]

You can't take CRISPR seriously? Jennifer is the godmother of this amazing breakthrough and she's speaking.

[@justayoutuber1906]

Yet you still post here