Direct Thrombin Inhibitors and Factor Xa Inhibitors (DOACs) - Pharmacology - Hematology

[@MedicosisPerfectionalis]

❤️ 💊 Cardiac Phrmacology: www.medicosisperfectionalis.com/products/cardiac-pharmacology-course/

[@munakhalil8448]

Love the video! There is actually since 2019 an Antidot for Factor Xa inhibitors, called Andexanet alpha, which is a Factor X fragment, that competitively inhibit the binding of anticoagulants to Factor Xa.

[@emyly103]

I WAS LOOKING FOR THIS COMMENT

[@omarelgedawy1796]

It is the first time for me to watch a video on your channel but they are really amazing ❤ ❤

[@MedicosisPerfectionalis]

Thank you 🙏

[@hazoummm6076]

YOU'RE A LIVING LEGEND

[@douglasbennett9044]

You make learning so much fun 😂

[@MedicosisPerfectionalis]

Thank you ☺️

[@yanbingzhu2550]

We had a patient overdosed with a huge amount of eliquis(a couple of dozens at least). He was bleeding heavily with minor cuts when shaving. The doctor ordered PT/INR, PTT. I was like "it is not gonna work because it is an Xa inhibitor......but fine. We will do it. There is no loss for the pt except a little bit amount of blood. He probably lost more in this shaving activity......" Amazingly, the lab came back, showing the time was prolonged. I was like "what???!!!". That pt got lots of education from every nurse every day when he was hospitalized.

[@aylaaloatti4206]

you are by far my fav person

[@MedicosisPerfectionalis]

Thank you!

[@christopherlemi6034]

Best lecturer ❤ and making learning easier n funny 😂😂

[@MedicosisPerfectionalis]

Thanks a ton!

[@remestario]

Perfect time to upload this video few days from my hematology final. You're amazing doc

[@MedicosisPerfectionalis]

Thank you so much 😊

[@dr.m2844]

Amazing video😮 I love it 🙏🏼😍😇😇❤❤

[@motionisdead9796]

I'm not sure how far, or how near is my question in relation to the current topic, but I'll still ask. I've been having problems that include: join pain, GERD, abdomen swelling, overall numbness, brain fog, dry eyes(hella red) and mouth(it burns), dry scaly and red skin(the redness is conditioned by the position of extermities, if I have my hands up, it pretty much disappears, if down, then it starts to swell and is red again -- does not affect scaling and dryness), shortness of breath, as well as extreme fatigue. Did a bunch of tests. Blood tests' came sort of fine(decreased MPV, PDW, and IG -- increased Mono). My thyroid is k. Liver, only has decreased ALT. IgE is elevated(1616 IU/ml), had done tests and I'm only allergic to mites(d pteronyssinus). Haven't done allergy tests only for mold/fungi. Ana came positive though. 1:320. The thing is, as I did specific ANA, as well as more specific antibodies for SSc and Dermatomyositis/Polymyositis, and every antibody there wasn't in a concentration high enough to be considred as positive( I did Sm/RNP, Sm, SSA, RO-52. SS-B. PM-Scl, Jo, CB, PCNA, DNA, NUC, KU2, Mi-2, Hi, RIB, DFS70, PDGFR, Th/To, PM100, PM75, NOR90, Fib, RP1, RP155). Currently doing Lupus Anticoagulant test. So here's my question. Is there anything I can do to get a diagnosis? This range of testing cost me a shitton of money, the symptoms are getting worse pretty much on a weekly-to-monthly basis, and I'm on the verge of mental collapse. Would be grateful for an advise from your perspective.

[@ceehaychh]

I’m doing a trial for a new anticoagulant that inhibits FXIa and i want to know why they theorise it’s better than FXa. Would really appreciate your explanation! It’s a new drug coming out so your video would be very educational as FXIa videos are so limited on youtube.

[@darkwarrior4754]

Bravo 👏🏼👏🏼👏🏼

[@MedicosisPerfectionalis]

Thank you so much 😊

[@cryalot378]

love your videos! thank you so much, they are really helpful

[@MedicosisPerfectionalis]

My pleasure 😇

[@aventadorgamer1575]

U teach so amazingly 😍😍loved watching Ur videos..keep teaching us!

[@thetravelmate9680]

Cheers mate, awesome series!

[@MedicosisPerfectionalis]

Thank you so much 😊

[@yanbingzhu2550]

Medicosis, Why does argatroban and Lepirudin affect PTT? Do they also inhibit some intrinsic pathway clotting factors?

[@bibeksharma1767]

THANK YOU VERY MUCH FOR YOUR VIDEOS .

[@MedicosisPerfectionalis]

My pleasure 😇

[@BethanieRussell]

Love your humor lol

[@MedicosisPerfectionalis]

Thank you 😊

[@thamisanqadeputy7695]

🥇🥇🥇Take off that mask we know that you are Einstein's cousin

[@MedicosisPerfectionalis]

Haha 😂

[@emersondelamere3555]

Medicosis, but what about andexanet Alfa? Is that not an antidote?

[@smile9252]

Hello u make pharma really very easy .. can u please make a video on diuretics

[@MedicosisPerfectionalis]

Thank you so much 😊 I have many videos on all diuretics in my Cardiac Pharmacology Course: www.medicosisperfectionalis.com/

[@Adam_Al-Dawoudi]

❤

[@MedicosisPerfectionalis]

🙏

[@abdalrahmanSham]

NICE

[@MedicosisPerfectionalis]

Thank you 🙏

[@giseleho9730]

How do I get the filled out table 😗?

[@sudani68]

Why ArgaTROBAN montitored by PTT ?does it have something to do with intrinsic pathway?

[@pavanbevoor8636]

Tq doc

[@MedicosisPerfectionalis]

My pleasure 😇

[@mnb7947]

Thanks Dr,can u make a next video on fibrinolytic drugs

[@MedicosisPerfectionalis]

I did already...Check out the playlist "bleeding and coagulation"

[@mnb7947]

@@MedicosisPerfectionalis okay 👍 thanks .

[@ahmedalfi8487]

Andexaner alpha is antidote for DOAC

[@karthickpriya_p_9543]

Can u make a video about superficial and deep reflexes ... Physiologically and in pathology condition .... I tried to find out ... But couldn't have a complete clear idea ... Hope u will help me ....

[@MedicosisPerfectionalis]

Good idea

[@emmag5569]

ive never laughed while studying for pharm until now

[@MedicosisPerfectionalis]

:)

[@aryanpandey2576]

You use notability or good notes?

[@MedicosisPerfectionalis]

Send me an email

[@UKFISGODLIKE]

Is there any chance to talk to you for 5 minutes? You could safe my life. Casual Doktors csnt help, because they don't understand the medications on your level.

[@osamaali330]

The god save you

[@MedicosisPerfectionalis]

Thank you 🙏 You too!

[@lynjohnson2778]

BANANA REPUBLIC LMAO