Diuretics and Antihypertensives - CRASH! Medical Review Series

[@lobzangdrukpa9554]

By the way we can use Labetolol in pregnancy....

[@mohamedshembesh8688]

it is used for pregnancy hypertension no?

[@uttamkumar097]

can you clarify the mechanism of action of thiazide diuretics? its little confusing how does the na/cl channel blocks the na/katpase pump if more na is available to the na/katpase pump.

[@olgamati9]

From what I understood: TZD blocks the Na/CI symporter - distal convulated tuble-> more sudium in the lumen traveling to the collecting duct. In the collecting duct this sudiun is absorbed via the ENAC channel on the epicla membrane, and than via the 2Na/3K that is on the basolateral membrane to the blood, and the K is transported to the cell; the K than secreted from the cell to the lumen via K channel. More K in the lumen also activates K/H which causes secretion of H+ and thus alkalosis. Because of the volume deplition there is also activation of the renin - aldosterone. Aldosterone further activates the 2NA/3K -> exacerbation of the hypokalemia.

[@kinesonc]

He made a mistake. Hes a physician. He shouldnt make such basic errors

[@TheMimibonheur]

Amazingly not enough content on ARBs that can be used better first line and not only when ACE are not tolerated as they seems as efficient and better tolerated... ?

[@DrDinooshDeLivera]

Thank you! :)

[@lifeincheck3198]

Thank you so so much

[@bisheralhasan5768]

doesnt nitroprusside cause cyanide poisining to the baby? why not use labetalol IV?

[@adilhanif7960]

Hey thanks for such informative video!! I have been looking for this question.. How the loop diuretics are effective in renal impairment while others diuretics are ineffective. What's the underlying reason. Kindly clear this confusion thanks.

[@jigarnayak22]

Thnks a lot sir..god bless u....u aare making best drs by you tube👌👌👌👌👌