DNA Origami: folding on the smallest scale

How do you fold DNA into the shape of a crocodile? Kerstin Göpfrich is a doctoral student at the Department of Physics, University of Cambridge, researching on DNA origami. DNA origami is the art of folding DNA into three-dimensional nanoscale structures. While smiley faces and various artistic shapes have been created from DNA as proof of principle, the research group of Dr Ulrich Keyser is using DNA origami to build technologies on the smallest scale. They have created tiny DNA channels, which could deliver drugs or kill malfunctioning cells.
Together with film director and editor Axel Bangert, animator Elisabeth Hobbs, origami artist Gabrielle Chan and sound designer James Rogers, Kerstin takes us on a journey through the macroscopic world of paper origami and the microscopic world of folding DNA.
Researcher: Kerstin Göpfrich
Department: Cavendish Laboratory
Film makers: Axel Bangert, Lizzy Hobbs
Cambridge Shorts allows University of Cambridge researchers at an early stage of their career to work with artists and film makers to make films using innovative ways to visualise research processes and outputs.

[@swarupdey3099]

What a beautiful representation! As a researcher of DNA origami, especially artificial DNA origami ion channel, I am surely going to use parts of this video in my presentation. Thank you so much for creating this.

[@racheltudorbest3915]

A witty visual exploration of this subject !

[@stemreactorbiotechnologyfo5610]

This is a really great video, I would like to show it to a high school student workshop about the potential future applications of DNA technology. Would that be alright?

[@kerstingopfrich6424]

+STEM Reactor Definitely! I also turned it into a TEDed video, specifically for high school students, with some additional material and questions: ed.ted.com/on/IXN5mtsM

[@stemreactorbiotechnologyfo5610]

Thank you so much! That's a really great resource!

[@roctjardes]

Kudos to Mr Thoki Yenn for giving us the DNA-4 folding pattern

[@wowshamanful]

Brilliant!!!

[@MrGreycoat]

Amazing!

[@GiovaniCeotto]

Great video, really interesting and easy to understand! What are some of the diseases that DNA origami could help cure or prevent? Will it be used majorly for drug delivery systems or can different DNA shapes act as a healing drug itself?

[@smsmxsmsm6371]

wonderful...but must rapid this scientific step more and more ...it require hard daily thinking and inviting evry second...great job .

[@manimaladas649]

Impressive.

[@albertjo9281]

woooooo magic

[@jiyakuches220]

it's more dna for us