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DNA Replication Animation - This animation video lecture explains the DNA replication process in details including DNA replication, elongation and termination. Process of bacterial DNA replication involves a number of proteins coming together in a complex machine DNA replication begins at a single defined DNA sequence of 245 base pairs called only see a protein called DNA increases in concentration as a cell grows and gets very cell division this protein as a complex with ATP can force the onset of initiation by binding to specific nine base pairs repeat or EC the binding distorts the DNA leading to the opening of the adjacent 13 base pairs repeats in the DNA of the opening of the DNA allows protein complexes to enter the replication bubble and bind to the single-stranded DNA each complex consist of the DNA humour case also called DNA B and a DNA fever caseload are also called DNA see the DNA fever caseload is open the DNA humour case protein rings in place the wings around the single-stranded DNA promoters are then released the humour cases use energy from ATP hydrolysis to unwind the DNA helix a tribute to replication forks its DNA humour case recruit an enzyme called DNA primates which synthesisers and RNA primer, DNA template and RNA primer is on its and a three prime hydroxyl group which is required as a starting point for DNA polymerase to add DNA nucleotides the replication polymerase in E. coli is called DNA polymerase three DNA polymerase three complexes of the rate of application forts by protein complexes called clear borders) is also clearly of the protein complexes called sliding clamps the clear blue replaces the sliding clamp onto the DNA and places and attached DNA polymerase three complex next to the sliding clamp the sliding clamp holds the DNA polymerase imposition on the three prime to the growing spray and as the polymerase synthesises new DNA nucleotides with complimentary basis to the tablet or one by one in the five prime to 3 prime direction the synthesis of DNA in the direction of the fourth occurs continuously to the end of the tablet piecemeal squared is called the leading sway and in contrast the other blue sky and call the lagging strand is built in fragments called Okazaki fragments a simplified diagram shows the key differences in the leading and lagging span is known to the tablet scram is a type well with a three prime and five prime a.m. is all you need in opposite directions because DNA polymerase can add nucleotides only in the five prime to 3 prime direction leading strand grows continuously in the direction of the replication fork providing spray and can grow only in short segments as the parental DNA molecule unzips many proteins participate in DNA replication including those called single-stranded DNA binding proteins which quickly code exposed single-stranded regions of DNA and protect the single-stranded DNA from attack by nuclease is all those single-stranded DNA binding proteins are present throughout replication for simplicity we will make the in the rest of the process DNA replication continues as the DNA polymerase providing spray and meets the five prime end of the next primer causing the polymerase of the sliding clamp to disengage of the DNA humour case has moved approximately 1000 pieces as second RNA primer is synthesised of the fork the sliding clamp loader adds a new sliding clamp to the primer and then add the DNA polymerase to begin synthesis on a new Okazaki fragment the cycle continues for the wake of the template strands of the lagging strand now consist of Okazaki fragments with the segment of RNA at one and the RNA is cleaved by an enzyme called RNase H another enzyme called DNA polymerase one uses the three prime of age group of the adjacent Okazaki fragment to fill a large gap with the DNA nucleotides finally an enzyme called DNA ligase closes the remaining makes on the DNA leading a continuous DNA molecule in this way in E. coli chromosome is replicated at to replication forks all the way around the circular molecule.
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DNA replication initiation
DNA replication elongation
DNA replication termination
DNA replication in prokaryotes