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The quality of the radiation produced can differ between radiotherapy machines. The quality of radiation depends on the type of radiation, its energy, and its penetrating ability. These characteristics should be experimentally measurable and confirmable. Several physical measurements, measuring techniques, and units help to increase radiotherapy efficacy, in accordance with the principle of primum non nocere. Dosimetric measurements are performed in patients, and water or tissue-equivalent phantoms and physical treatment parameters are determined.