Dosing of Peptide Therapies

Like many things in medicine, we always try to listen to the patient’s body and how they are responding.
Want to OVERCOME chronic pain? Go here: regenerativepe...
If you’re new to my channel, my name is Dr. Drew Timmermans, ND, RMSK. I’m the founder of Regenerative Performance in Gilbert, AZ, specializing in interventional orthobiologics, which is just a fancy way of saying we help people reclaim their life from chronic pain without steroids or surgery. We challenge the conventional pain management approaches by addressing the root causes of chronic pain.
How I got here…
22 yrs old: Graduated with a Bachelor of Science in Kinesiology from the University of Western Ontario.
23 yrs old: Competed as a long sprinter, anchoring the 4x400m relay to a silver medal at the Canadian national championships, contributing to Western's first national title in men's track and field.
23 yrs old: Started working as a personal trainer for GoodLife Fitness in Canada, quickly becoming one of the Top 10 Personal Trainers nationwide.
23 yrs old: Herniated two discs in my lower back, ending my track and field career and sending me into a multi-year battle with chronic pain.
24 yrs old: Enrolled at the Southwest College of Naturopathic Medicine (now Sonoran University of Health Sciences) after discovering my passion for naturopathic medicine.
26 yrs old: Still battling chronic back pain, I finally became pain-free through a platelet-rich plasma injection.
28 yrs old: Graduated and become a licensed naturopathic doctor.
29 yrs old: Completed the first-ever residency in regenerative medicine and integrative pain management at the Neil Riordan Center for Regenerative Medicine.
29 yrs old: Co-founded Regenerative Performance to help people with chronic pain just as I had been helped.
Today: We help people who have chronic joint pain reclaim their life with cutting edge treatments like platelet rich plasma, and stem cell therapy.
To everyone battling chronic pain, remember that your story is still being written.
Never give up.
Dr. Drew Timmermans, ND, RMSK
FULL DISCLOSURE: I create content to share my expertise and help as many people as possible. My goal is to build trust and provide valuable information to those seeking alternative solutions for chronic pain management and bring in new patients into our practice.

[@stephanharrison5ih5ygt30]

How do I dose oxytocin 5mg peptide, water ratio etc

[@annea549]

Hi thanks, would you be able to recommend any peptide companies in the uk please? Xx

[@absolutecrypto95]

Love all your posts and appreciate your info

[@DrewTimmermansND]

appreciate you sharing this!

[@absolutecrypto95]

hi Dr Drew I'm taking the rapid 500 BPC157 from the company you recommended I WAS ALREADY on BPC157 from a pharmacy and don't really feel any difference on the new BPC157 reason I switched was $330.00 for 30 days. Any suggestions?

[@chiefhiggins6471]

Hey brother. Love uour channel. I have a nuanced but important question, but really it could apply to any peptide that's been acetylated. I've asked this question now probably 20 times at depth, no one seems to answer it. My question is related to Semax nasal spray, but like I said-could apply to any peptide. I'm wanting to know what the difference is between acetylated and non acetylated peptides, especially when it comes to peptide affinity, absorption, and degradation. I've only been able to find one video on this topic, which suggests that acetylation might be better, but the video is confusion bc it combines ammidate in the topic. I want to take this peptide long term, so I don't want my body to not respond after long use. I found that the non acetylated Semax worked better, but that could be bc of factors. Any education you could offer would be great!

[@DrewTimmermansND]

In general, acetylating peptides improves stability of the peptide (peptides are notoriously unstable) and therefore improving bioavailability.

[@angelcarlos3085]

Hi i was wondering too aboit ghk cu oral for joint shoulder tendón repair is it helpful orally and how much is a good dose?? Thanks

[@ryanisfollin]

I saw somewhere you suggested a website to order BPC? I cannot find it now that I want to order

[@DrewTimmermansND]

here you go! We use the InfiniWell brand as they use the arginate salt. We have a 20% patient discount code on our website regenerativeperformance.com/supplements

[@baronharkonnen1217]

BUT WHAT IS ONE DOSE OF PEPTIDES??? Is it 5 grams of BPC157? Is it 1 gram of BPC157? Is it 5 mcg of BPC157? How about including some actual numbers...

[@DrewTimmermansND]

If you took a few moments to search my youtube channel you'll find I have dozens of videos on peptides and i talk about dosing

[@yolo7128t6]

Just look in the other comments, it's 300mcg for bpc157 and 500mcg for tb500

[@cppoly]

For BPC 157 and TB 500 to treat shoulder SLAP tear, can both be infected into stomach once per day? What's the recommended dose for 150 lb male. Thanks

[@DrewTimmermansND]

Standard dose of BPC-157 is 300mcg subQ and around 500mcg subQ TB500 (there's a lot of variability with this one). Yes stomach injections are fine

[@cppoly]

@DrewTimmermansND awesome, thanks! Any input on TB 4 vs TB 500 for healing these tears?

[@DrewTimmermansND]

we refer tb4 over tb500, but we just can't get it from compounding pharmacies because of the FDA

[@jonathanreilly6741]

@@DrewTimmermansND hey doc I just ordered BPC-157 and TB500 both 10mg bottles. I’m going to be starting injecting these both subcutaneously daily with the amount you commented above (BPC - 300mcg/day TB500 - 500/mcg/day….how much bac water do I add to each bottle for this? Thanks for what you do!

[@jonathanreilly6741]

And also, how many units of an insulin syringe would I fill to for each peptides daily injection?

[@Terminatortx33]

Hi im a 50 year old male and tore my gastrocnemius playing tennis. This is the second time now in the same place but bigger. I was thinking off trying BPC-157 - Question what would my dosage be? And should i inject it into my calf muscle area?

[@DrewTimmermansND]

I'm so sorry to hear that. You should really consider getting PRP injected into the tear. As for BPC-157, If you are working with a physician and can get injectable BPC-157 from a compounding pharmacy, then that's great. If you aren't, then we don't recommend the injectable version as this would require you to purchase BPC-157 from a research chemical website and these peptides are commonly contaminated with LPS, a bacterial endotoxin, which can cause really bad side effects. Instead of using injectable, we then recommend using an oral arginate salt. We use the BPC-157 capsules from InfiniWell as they use the arginate salt. If you want a discount code, we have one for our patients on our website regenerativeperformance.com/supplements. Once on that website, click the InfiniWell link, and then choose the product labeled 'BPC-157'. When you hover over the product, you will see it says 'Original Formula' above the ingredient box. This is the version that does not have SNAC, which we find works better. The most common starting dose we use with patients is 500mcg, once per day on an empty stomach. The time of day doesn't really matter in our opinion. We normally have patients take BPC-157 for at least a month to determine if they see improvements, but sometimes it takes longer to see effects as tissue healing takes time. We then have patients continue on the BPC-157 for several months, and then we might trial taking them off to see if their symptoms remained improved or if they regress. If they regress, we put them back on it.

[@MrIt83]

I just bought a box of 60 capsules bpc157...on the label it says 1 capsule twice daily.... but from your video I can just start with one... right?

[@AnotherOverTaxedTaxPayer]

Will it work intermuscular or must it be Subconsciously? I had rotator cuff surgery at end of December 2022

[@DrewTimmermansND]

it can work as an intramuscular injection, but subcutaneous works just as well so I don't see the need to do IM

[@AnotherOverTaxedTaxPayer]

​@@DrewTimmermansND Sorry for the misspelling. Auto correct sometimes works against me. I already take TRT IM, so I was thinking of just doing it all in one shot. BUT, TRT is in oil base (oil-soluble) if I recall. Now that I think about it, I am not certain if it would be smart to mix.

[@DrewTimmermansND]

Yea don't mix those. Just pin separately

[@plasmaballs1]

What is a good thymosin beta 4 protacal for home

[@DrewTimmermansND]

Standard dose is 750mcg once daily for 3-6 weeks. Can't say if that's right for you or not as I'm not your physician.

[@CashewsClayy]

Enjoy having antedonia when you take BPC

[@DonaldGaron]

Should I take the BPC157 a few hours before going to bed? It makes sense to me to take it at that moment instead of early in the day.

[@DrewTimmermansND]

we haven't seen any benefit to one or the other, so I would do what makes most sense to you

[@DonaldGaron]

@@DrewTimmermansND would the explanation be that the bpc simply accumulates in the body and '' is constantly working '' like a typical medication, for example for the treatment of bipolar disorder, if you take it daily? Basically, if you needed to take it before sleeping to maximize healing, I feel like it would mean the bpc would only have an effect for X hours. So taking it during early in the day would have MUCH LESS of an effect for healing as a consequence

[@DrewTimmermansND]

We actually don't know much about the pharmacokinetics of BPC-157 in the body, just the effects. So an argument could be make for before bed and we would just need larger human studies to know for sure

[@cannalabs]

@@DrewTimmermansND i just had achilles surgery but am skeptical of buying vials of stuff online as pretty as it looks. Should i talk to my surgeon on my 2 week post op and see if she can prescribe or is there something you do personally as far as intake and prescribe over phone? Let me know thx

[@DrewTimmermansND]

Your surgeon won't write you a prescription as 99.999% chance they don't even know about peptides. If you'd like to see about working with us to get pharmaceutical grade peptides that are safe, along with better protocols for healing, then head to our website - regenerativeperformance.com/contact. Book a call with one of my residents as they are currently overseeing the remote appointments for peptide management.

[@bh9262]

I've been taking bpc oral for 6 months. 800mcg daily. Should I taper off. Is stopping cold turkey risky or dangerous?

[@gavincosgrove]

That's alot

[@bh9262]

⁠what does that mean exactly?

[@gavincosgrove]

@@bh9262 800 is alot? I'm only using 500mcg

[@dylanmeyer9117]

⁠​⁠​⁠​⁠​⁠@@bh9262from the research I’ve seen I haven’t taken it but most is 500mcg for a month oral and I would recommend tapering off