Down syndrome (Trisomy 21) - causes, symptoms, diagnosis, & pathology (Updated 2024)

What is Down syndrome (trisomy 21)? Down syndrome, or trisomy 21, is a genetic condition associated with a partial or complete copy of the 21st chromosome.
What's new in the 2024 version: outdated language updated, introduction and recap added, cytogenetic types added for clarification.
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[@iis_idk]

Thanks for sharing the knowledge!

[@osmosis]

Our pleasure! 💕🥰🫀

[@MedicoPharmacyDoctor]

Thanks for the Informative knowledge 😊

[@osmosis]

Any time! 🥰❤️🙏🏼

[@well-imBATMAN]

Nice ❤

[@osmosis]

Glad you like it! 💕🥰🫀

[@AyanKhan-vw2mi]

Where can we get your notes of these videos

[@osmosis]

Hi! While we do not have PDF or PPT versions of our videos, we do have high-yield notes and decision-making trees that you may access at osmosis.org anytime 😊

[@MACHARIASHERRYNEWAMBUI]

Hello. Which app do you use to make these?

[@osmosis]

Hi, thanks for asking! Here’s how Osmosis videos are made: www.osmosis.org/blog/2020/11/27/how-osmosis-videos-are-made# 👍🏼

[@rachanabehera7990]

Have a doubt : If mother contributes extra copy of chromosome, does that mean the mother also has down syndrome and it passes onto the child? So that means Down Syndrome is also an inherited condition along with being a genetic condition?

[@FishareFriendsNotFood972]

People with Down syndrome rarely reproduce because one of the impacts of the condition is infertility in men and reduced to no fertility in women and complications with carrying to term. Only Fifteen to thirty percent of women with trisomy 21 are fertile and they have about a 50% risk of having a child with Down syndrome. There is no evidence of a man with Down syndrome fathering a child.

[@FishareFriendsNotFood972]

Down syndrome results most frequently in infertility.

[@FishareFriendsNotFood972]

Bold of you to assume I'm not a single celled organism, sir