Electrophilic Substitution of Pyridine

[@ashikashakeer6956]

Very effective . Thankyou sir!

[@sharief037]

sir can you please explain same as nucleophilic substitution reaction of pyridine

[@tannugupta7225]

Thank you

[@namratakude8884]

Can you explain nucleophilic substitution reaction

[@DrAnilPalveAcademy]

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[@ayayatt]

Thanks

[@nehasinghneha6932]

sir please repeated the reaction of pyridine in nucleophilic

[@gohilrohan3796]

But why position 2 and 4 are unstable? Reason?

[@meadhbhnicamtha]

If the electrophile attacks at position 2 or 4, Nitrogen is left with a positive charge. This positive charge means the molecule is less stable

[@suyashmallik118]

Why doesnt the electrophile attack on the nitrogen atom?

[@realfacts9183]

Yes it attacks . to prevent this reaction is carried out at special conditions..(usually at high temperature) And also because of this reason they give limited electrophilic reactions