Drug delivery by Magnetic Induction Heating | Drug DOX release from Magnetic hydrogel Nanoparticles

Magnetic Field Responsive DOX Drug Release from Magnetic polymer coated Fe304 iron oxide Nanoparticles by Magnetic Induction Heating. Induction heating, hypertherima treatment.
Magnetic nanoparticles (MNPs) generate heat when a high-frequency magnetic field (HFMF) is applied to them. Induction heat is useful not only for hyperthermia treatment but also as a driving force for drug-release. In this study, we synthesized, characterized and biologically tested multifunctional Fe3O4-based drug delivery systems for such an application. The nanosystems were successfully prepared with a small size, high saturation magnetization and high drug loading. The Fe3O4 core in an alternating magnetic field could generate enough heat for both effective hyperthermia therapy and doxorubicin release from the alginate shell for chemotherapy. Also, a folate factor was attached to the nanoparticles to help the system to enter and stay in the tumor cells for a longer time.

[@TheEliandres]

Hiii, thanks for the demostration, could you say me if the white material in the coil is to thermal isolation?

[@polymerscope6881]

Yes, it surrounds the copper coil for thermal insulation.

[@hrayatpisheh187]

Hello, you may say the percentage of each of the materials used. Or introduce the related article.

[@polymerscope6881]

U can read here; title " Synthesis of Magnetic Field Sensitive poly(AAm-co-VSA)-PVA/Fe3O4 Nanospheres and Investigation of Their Drug Release Behaviors Under AMF" , URL = dergipark.org.tr/en/pub/ejosat/article/898018, DOI NUMBER: doi.org/10.31590/ejosat.898018

[@littlebit7695]

Could you mention the frequency of your induction heater and the size of MNPs

[@polymerscope6881]

320 kHz, MNP size about 50 nm, Polymer coated MNP abaout 220 nm.

[@littlebit7695]

@@polymerscope6881 thanks

[@sofaroww8260]

What is this all about, I don't get it

[@polymerscope6881]

This method can be used in controlly drug delivery systems and hyperthermia in medicine for locally treatment.

[@김장혁-s7e]

Sir, can I know the voltage and frequency of induction heater?

[@polymerscope6881]

320 kHz, 4mT, 5 Amper