Dynamic Instability Of Microtubules

[@hafsaaleem5688]

OMG love the intro and how dramatic it was. Kept me entertained but also helped me learn THANK YOU!

[@ahmedkeremsayar]

ı felt like God was instructing me on this topic because of the soundtrack choice and clear explanation thanks

[@uncleStalin]

😂😂😂😂😂😂😂😂😂 god himself is proud of you

[@charlientumba6673]

😂

[@MrTRANnysaurus]

got that X-files vibe to it

[@Murtaskegg]

Great job. I love the animation, narration and especially the choice of music

[@russelmiller7311]

The opening of the video is good. As microtubules play an essential part in a wide range of fundamenta1 cellular events. It's significant to know more about it.

[@benstapleton5210]

Very useful post! Helped me ace my cell test! Great work!

[@SadeddinYamlikha]

Glad to help!

[@yaminaboub-jo2lb]

I have in exam in two hours . This saved me . Thanks ❤

[@SadeddinYamlikha]

my project for cell bio

[@ramasoumakieh1233]

Good job

[@SadeddinYamlikha]

Thanks

[@maleksoumakieh2504]

Not bad

[@michaelosullivan9753]

my project for cell bio

[@aphysique]

Stuart Hameroff & Consciousness brought me here!!!🙏👏

[@50observer]

This is an amazing video and explanations. I think you have given the girls some competition!!

[@charlottehivet1139]

Thank you for this video, it helpped me a lot to understand what was the dynamic instability !

[@ilgn3896]

It helped me to understand so many things thank you so much

[@alexmoore2466]

Great concise explanation and answers!

[@Mohammad-xe2qw]

Great job with great music 🎶 🤩

[@bobboo2733]

Does this video have audio taken from another video on youtube?

[@llamallama2007]

Great video, helped me quite a bit, Thank you!

[@simusic8346]

Thanks for the video, it helps me a lot in my studies

[@knowledge.seekers]

Thanks for easy understanding

[@salmaabdalla4680]

This was SUPER helpful, thank you

[@Habubachu]

this music straight FIRE

[@dennisgarber]

I am still trying to get my head around how this relates to cancer. My guess is that shrinkage would split the chromosome, mitosis, which we don't want in cancer. Stabilizers work in different ways, which I need a visual for. ..am I grasping this correctly?.... I am also trying to understand relationship between filopodia, calcium channel blocker , and cancer motility. As well as integrin and how it affects cancer spread.

[@timbergling1064]

is there any marker that can specifically indicates the disassembling terminus of microtubules? thanks!

[@SadeddinYamlikha]

I'm sorry, I don't have an answer for your question

[@timbergling1064]

thank you all the same :)

[@WillardVanDeBogart]

Very much enjoyed this video. Questions could be clearer. First time Ive see the microtubules extending from the cell. What equipent did you use to video this?

[@SadeddinYamlikha]

Videos were taken from "Garland Science", but not sure what technology was used to capture the videos.

[@HPo10tial]

My guess is live cell confocal microscopy

[@prawinkumar8491]

It is an cylinder like arrengment with 13 tubule protein

[@islandbuoy4]

but your cylinder appears to have flat sides and 3x3x3 sections are observable

[@freemensudhaman]

Very good video. You might very well be interested in Stuart hameroff research in this subject.

[@kunukandayashodha2166]

I learned what is dynamic instability

[@kmanc8571]

I thought rescue was when an unhydrolyzed GTP was put on the beta end of the microtubule to make a new cap, not entirely sure I heard what you said right

[@SadeddinYamlikha]

+kmanc rescue is when GTP hydrolyze to GDP which causes the microtuble to grow

[@kmanc8571]

Sadeddin Yamlikha I'm pretty sure that's wrong :P catastrophe is when the GTP of the + end is hydrolyzed into GDP which makes the chain unstable & starts a catastrophe. Rescue is when the + end is "capped" with a tubulin dimer in which the beta part has an unhydrolyzed GTP molecule thus enabling the microtubule to resume growing.

[@SadeddinYamlikha]

+kmanc, Sorry, I was wrong in my previous comment. When the microtubule is shortening, its end has exposed GDP bound subunits and depolymerization occurs. To stop the depolymerization and change back to polymerization (growing), GTPs have to bind forming a cap. This switch, the actual change from shrinking to growing, is called rescue. Growing itself is not rescue. While a GDP is hydrolyzed every time a new tubulin is added, this growth is not called rescue.

[@kmanc8571]

yep.

[@RajeshSingh-hr1xy]

Rajesh chakradhari

[@DrKatherineBalochND]

I like your music - where is it from?

[@SadeddinYamlikha]

Music: "Martian Cowboy" Kevin MacLeod (incompetech.com)

[@clasherclasher317]

epic music at the start

[@conceptualbiology4450]

Plants do have centrosome but not centrioles inside it.. bdw great vedioo...

[@ns9176]

this is great even though it's terribly hard for me to discern what the person asking the questions is saying

[@Jesusmoon23]

What software do you use? Great project!

[@SadeddinYamlikha]

Thanks, I used Sony Vegas for production and Blender for animation

[@galikrayden6199]

Why the scary music?

[@SadeddinYamlikha]

Sci-Fi, just a personal preference from back then.

[@clappypappy7677]

what is the ominous music man lmao

[@zuluzero4659]

Great

[@arpittyagi6404]

Nice..

[@medicolearning..3685]

can u translate it in urdu?

[@ameersaifi8097]

"what habbez"

[@99.99]

Lol. A 35 second intro for a 5 minute video.

[@kunukandayashodha2166]

please don't shuffle voices

[@ranvijaysingh5002]

0:53

[@caniko2]

I hate the soundtrack...

[@SadeddinYamlikha]

I'm sorry to hear that, I'll work on choosing better soundtracks for future videos

[@amira-ye6lj]

good content but why does the guy asking questions sound 'foreign' smh

[@SadeddinYamlikha]

amira abdulhadi maybe because English is his second language, and he had thick accent back then 🤔