The RAS / RAF / MEK / ERK Pathway Part 3

In this video we discuss the RAS/RAF/MEK/ERK pathway, which is activated by Receptor tyrosine kinases.

[@guppyngizmo]

Thank you for this video series. You explain everything well and take nothing for granted. It helps me a lot as find this topic very confusing. Your techniques of always explaining and revising is very useful. Keep up the great work!!!

[@smnsourabh77]

Basics to advanced level.. nice work.. i love it..

[@heatherbisbee5613]

This may be too in detail, but what's your source that pp2A causes 14-3-3 and RAF to dissociate?

[@suraalshamma9180]

@28:18 " it reminds them of a horrible past of history " LOOLLL :)

[@vwellem]

What about GRAF ? I often hear about that.

[@margaritaschuster423]

nice video! thank you :)

[@nicholasheimann4629]

Good detail!

[@马马-d6u]

good things

[@Mltnzle]

You are very goot at lecturing but at the same time you Always go into too much detail

[@schaniotakis]

Mehmet Altun that’s the whole point

[@Rosey42Walf]

Hey I do highly apologize for being random but do you have any opinions on this type of gene information I recently got it on a cancer screening lab test my doctor's not really telling me information about it so I'm trying to self-research for myself any kind of help would be highly appreciated. On the 84 multicancer panel blood lab test I had done this is what they found on it I'm just having troubles understanding it since again like I mentioned my doctors are not really being honest with me on a lot of stuff and I don't know if they're doing this because they don't think it's a problem or they think I'm a worry wart but how can I not when cancer is really thick in the family and they find something and don't go into detail with me about it... But they found this.... hras exon 5 c.481C>T (p.Arg161Cys)

[@nicoleblasi8067]

i believe that means there is a mutation on hras exon 5. i do not know what c.481C>T is referring to, but .Arg161Cys means that amino acid 161 was mutated from Arginine to Cysteine. I hope this helps!

[@nicoleblasi8067]

disclaimer: this does not mean it is a bad mutation. there are many different types of mutations, and a lot of them are silent, meaning they do not affect you, or change anything regarding protein function. I hope your doctors where able to speak to you about it! stay strong.