Embryo Grading 101| Embryologist Jess Bailey | National Infertility Awareness Week 2022

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@melissasmith1810 2 ай бұрын

I had a 6BB that is frozen for a FET. I am curious of your experience with hatched blastocysts that are going to be frozen for an FET. There seems to be a lot of controversy if fully hatched blastocysts have lower pregnancy rates. Some studies suggest they are more fragile. I heard another embryologist say that you don’t want a day six because you want it to hatch and develop inside the body. I am wondering what the data suggests in your clinic. I have a 6 BB and 2 4 BCs frozen that are euploid. thank you for doing this video! Thank you!

@Boston_IVF 2 ай бұрын

Great question, Melissa, here's some more information about day six embryos from Chief Cryobiologist Jessica Bailey: That was an older way of thinking as there was originally some data that suggested that there was a higher rate of aneuploidy (an abnormal number of chromosomes) among day 6 embryos when compared to day 5 embryos. However, today, we look at this very differently. Many embryos used for frozen embryo transfer are genetically tested and only the euploid embryos (those with a normal number of chromosomes) are transferred. In this case, the concern for ploidy has been addressed. Additionally, based on our data of 100,000s of embryos, both those genetically tested and those that are not, we have found that day 5 and day 6 embryos have near equal implantation potential. Instead, we focus on the elements among the grading that do show some significant difference among the implantation rates. We have found the grade for the trophectoderm cells (those that become the placenta) are the most key factor for implantation and use this grade first when selecting embryos for thaw and transfer to the patient’s uterus.

@Boston_IVF 2 ай бұрын

Please feel free to reach out to our office with more questions here: www.bostonivf.com/getting-started/ask-Rhonda-a-fertility-question/