END OF TIRZEPATIDE COMPOUNDING? FDA Removes Zepbound and Mounjaro from Shortage List!

The FDA removes Zepbound and Mounjaro from drug shortage list. Is this the end of compounded tirzepatide?

[@lmktacwa]

Yup, have a 7.5mg Zepbound Rx but my pharmacy is out of stock. Seems like that would be a good case for allowing compound Tirzepatide as a substitute, then try to fill the Zepbound again next month. Obviously Eli Lilly is not being completely truthful about availability, and shame on the FDA for cowtowing. 😖

[@marimerf6685]

Report it to on the FDA Page

[@kimprindle4819]

Who can afford this!

[@alphatango4689]

I called to refill my prescription today at my compounding pharmacy. I was informed of this change. I lost over 100 lbs on this medication and it saved my life. Very frustrating

[@VernCrisler]

As some have reported, Eli Lilly won't release vials in higher doses because people will buy the higher dose vials, then split them up into lower doses. EL loses money that way and despite its woke attitude, profit is still the bottom line for these drug companies.

[@victoriagreen3441]

Exactly that makes sense what you’re saying. So therefore they ain’t going to do it. They’re smart about it becuz it’s all about the dollar sign for them and plus no concern for the patients that’s on these glp1 meds. Saddd though.

[@stevehofer3482]

The US government needs to buy out the patent under eminent domain to serve the public health.

[@teresahawkins6689]

My pharmacy done b12 with it , and They said they can continue

[@gablovesplantssydney]

If you read the FDA rules, they state that you need to change one of the base ingredients in order to have it be a significant change to the drug. This means that adding something like B6 is not acceptable under their rules. The reason for this is that it would be quite simple for a patient to take the drug and then take a shot of B6 or a pill of B6 separately to get the same effect. If you had a patient who was allergic to a preservative they put in the base ingredient and the compounders made the drug up without that ingredient then that would be a reason to be able to produce a compounded version. It also seems that if a doctor is continually writing that all of their patients are allergic to a preservative or to one particular component in the brand-name medication that will not be looked upon favorably so I don’t think that that would work as an excuse long-term to produce a lot of of compounded medication. You are correct that it doesn’t get around the patent infringement problem. You can look up the FDA website and read the instructions around the rules. It’s quite clear.

[@VernCrisler]

I'm still surprised that Novo Nordisk hasn't sued Eli Lilly for patent infringement. I guess adding a new receptor agonist to the original GLP-1 drug is not considered patent infringement, though it's pretty close.

[@randomupdates4013]

I had just started the compound, 2 shots in. Already lost 6 pounds. Irritating. Can’t afford like triple for actual zepbound. Going to complete the 4 weeks, but guess I’ll have to switch to semaglutide.

[@PurePharmas-qm3bk]

We sell only to research facilities. Was wondering why so many trying to order. Just adding B6 or B12 will not work with the FDA. We are looking into adding 3 or 4 peptides in small, beneficial amounts to overcome this issue

[@NorthlandSLC]

Cjc-1295 dac maybe?

[@victoriagreen3441]

Wouldn’t that change the medicine all together to something else? Plus would it work the same or not?

[@yesenia810]

Thanks for the information

[@victoriagreen3441]

That is still too high

[@ericromero8123]

Thank you

[@lahall4942]

Fantastic video

[@ChristyRisingerMD]

Thank you.

[@thedownsized]

great video - thanks for your insights!

[@jonathanzivan1885]

Do you have any recommendations for folks that would like to titrate off Mounjaro ? I’ve been on 15mg for 25 months. Huge success. But I’d like to safely get off without gaining my 80lbs back. Mainly I want to keep muscle mass, which can be a problem?

[@ChristyRisingerMD]

What an accomplishment! Honestly, I would recommend that you stay on the medication indefinitely. Obesity is a chronic health condition. Think of it like high blood pressure. Once your blood pressure is controlled with medication you don’t stop the medication. You can consider going down slightly on the dose or even consider taking it every 10-14 days but I believe you should be on some amount or form of the medication indefinitely. Studies have supported this recommendation as well. As always, talk to your own doctor before doing anything. Thanks for watching.

[@michaelclanton1152]

If pharmacy's sold viles of the API it would get around the restrictions and storing the vile for 3,6,9 months.

[@Gemma1558]

With the Eli Lilly direct, do they have someone the other will write you the prescription and if so, is there a fee or can I have the telehealth company I’ve been dealing with write a prescription for me to get it from Eli Lilly direct now that they’re not providing access to the compounded medication? Thank you.

[@ChristyRisingerMD]

To use the direct to consumer Eli Lilly pharmacy you need a prescription from your doctor for Zepbound.

[@Lowcarbkimmy]

If you trying to maintain is semi an good option

[@KT-hb5xp]

good

[@janicejune]

So even if you don’t have any comorbidities, you can still get the Zepbound through Eli Lilly and pay out-of-pocket?

[@ChristyRisingerMD]

You need a prescription from your doctor for zepbound to get it from the Eli Lilly pharmacy

[@reboundingback]

B12 in Tirzepatide is a good thing, my compounding pharmacy adds B12 because: vitamin B12 can help reduce nausea from tirzepatide. I do not get nausea side effect.

[@jonathanzivan1885]

I actually found that a very mild nausea, usually after eating a bit too much, really helped me to learn to readjust my eating habits.

[@VernCrisler]

But as I think Dr. Risinger said, that could be construed as possible patent infringement -- and compounding pharmacies are hesitant to sell generic tirzepatide for fearing of lawsuits.

[@teresahawkins6689]

Same here, they are saying they can continue, they were doing it before tge shortage

[@keithrichard391]

Fast,fast,fast

[@ZEPBOUNDGAINS]

I'm getting my Zepbound like normal.