ESC 23: OCT vs IVUS vs Angiography Guidance

Dr Gregg Stone (Icahn School of Medicine at Mount Sinai, US) shares the findings from a real-time updated network meta-analysis comparing OCT, IVUS and Angiography guidance in percutaneous coronary intervention (PCI) procedures.
The OCTOBER and ILUMIEN IV randomised trials both studied OCT-guided versus angiography-guided PCI. This analysis compared the overall effects of intravascular imaging in improving outcomes of the PCI procedure as compared to angiography, as well as IVUS vs angiography, OCT versus angiography, and IVUS versus OCT. The analysis included 20 randomised trials, and 12,428 patients.
Results showed that IVUS-guided PCI was associated with lower rates of target lesion failure as compared to angiography-guided PCI.
Questions:
-What was the reasoning behind this meta-analysis?
-What was the patient cohort and study design?
-What are the key findings?
-What are your take-home messages?
-What further study is still required?
Recorded on-site at ESC Congress 2023, Amsterdam.
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