Exosomes: nanoparticles offering a new future to cure disease | Shivani Sharma | TEDxManhattanBeach

Shivani Sharma believes exosomes - tiny nanoparticles in our bodies - may offer a new path to curing and managing disease. While first discovered in the 1980's, Shivani's breakthrough method of studying exosomes using the Atomic Force Microscope, offers scientists the ability to comprehensively study these fragile but powerful particles. A new frontier in microbiology, Shivani and other nano scientists are just beginning to understand the important role of exosomes in our body. Dr. Shivani Sharma holds a PhD in Biomedical Engineering. She serves as Associate Director for the NanoPico Characterization Lab at the California NanoSystems Institute at UCLA. Her primary area of expertise is nanomedicine, structural biology and biomarker development.
She is a founding member of the International Society for Extracellular Vesicles (ISEV) and has chaired sessions as well as delivered invited talks at several International/National conferences related to exosomes and cancer diagnostics.
Shivani serves on the Editorial board of two Journals. Her award-winning work has been featured worldwide. A Clinical & Translational Science Institute fellow at the David Geffen School of Medicine at UCLA, she also pursues active interest in enhancing academic-industry research collaborations for biomedical technology translation. She is a proud mom of twins, and her favorite TED Talk is Stuart Fierstein: The Pursuit of Ignorance. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at www.ted.com/tedx

[@rameshgupta6562]

No body in the world has examined exosomes by microscopy as Shivani Sharma has. I have gone through some of her papers, had an opportunity to meet with her and now this TEDx talk, she is superb in her understanding about these tiny particles I usually refer to them as "mail persons" meant to deliver the cargo to the right "Zipcode". (Ramesh Gupta, Louisville, KY)

[@chrish.5839]

Excellent presentation! Shivani did a wonderful job making this topic easily understood by those outside her field.

[@anugrahdeane3545]

Well done Shivani,God bless u nd give u more wisdom nd understanding.

[@LugalKiEn2126]

Interesting name. Anugerah means reward in Malaysia.

[@barefacebeauty9734]

Truly inspired

[@kemchobhenchod]

Just goddamn brilliant. Science benefits from your softer touch and brilliance. Thank you for realizing that the AFM was the key. I believe this is the birth of a new era of medical diagnostics and therapy and you are at its forefront.

[@alanmcrae8594]

Just like a single instrument (the AFM) can greatly advance a field of biological science, a single instrument like LIGO can give astronomy a completely new set of eyes on the cosmos. Sometimes it is simply mathematical theory that leads the way (General Relativity), but often it is a new instrument that lets us see what was nearly invisible before. A toast to the instrument makers: because of you scientists can see new ways to observe, learn and understand.

[@georgeR3Roadster]

but be very careful because bigpharma does not like at all this kind of research ! they speak about viruses all the time and want us to take pseudo GMO "vaccins" to fight the viruses !! they make healthy people SICK so they can treat sickness with their (multi$$$$$) pills and pseudo vaccins !! be careful !! thanks for your research that is so important !!! namaste !!

[@RogerWittekind]

Yes but we still have to figure out what the exosomes are saying but it is easy to do for Covid because it follows a number of flus where DNA damage occurred and the fact the inside of the exosomes is mRNA which is used by cells with damaged DNA to build brand new DNA via Reverse Transcription.

[@kalrasachin]

Good job Shivani! Awesome topic, and very well explained!

[@gavv1971]

Talk about how biotechnology can help create healthy exosomes communication, but it does not mention what making bad use of science would also have power to do wrong

[@RogerWittekind]

Sadly the don't want to tell us that mRNA drugs are trying their best to imitate Covid in replication and replacing our DNA via Reverse Transcription.

[@tarquineous]

This is how medical and health progress is made. Let's be appreciative !

[@naibsiabzoo7069]

มต​อึดอัด​8ตัป 5

[@MojoCuba]

I was just thinking the exosomes theory - very easily explains why some people might test HIV+ but never develop the AIDS disease !

[@jll1695]

Absolutely correct

[@trabiccolo879]

Can you distinguish an Exosome from a Virus, as an objective of RNA detection (RT - PCR) or under the Electron Microscope?

[@johncarr123]

Great question and I know why you asked.

[@trabiccolo879]

@@johncarr123 and Who can and will answer?

[@gavv1971]

David Icke says when the test with the RT PCR , for Covid 19, what they see are Exosome instead the virus I apologize for my english.

[@RG-iw7py]

@@gavv1971 Please, don't apologize. You made a point. Sorry, for me Icke and Alex Jones are agents of misinformation. Dr Andrew Kaufman talks about similarity between viruses and exosomes too. And that covid tests are 80% faulty, even CDC calls them problematic. The Telegraph, Australian tv according to Irish journalist Gemma O'Doherty are talking about faulty personal protection equipment and test with traces of covid virus being imported from China. Edit: Dr Andrew Kaufman, Gemma are right. Corrupt governments, Icke, Alex Jones are not trustworthy.

[@Kalin_sw]

Hi guys. There are also "Bacterial exosomes" and some health service personnel say that those are the best candidates to be what we call viruses, that can be secreted more intensively under bacterial stress (like 5G radiation)... I think the corona particles running around are bacterial exosomes, pumped out by bacteria trying to survive and reproduce following the 5G tests going on. This and our own exosomes are the symptoms we call flu, mostly coming from EMF and pollution.

[@NikhilMandrekar]

At 6:12 "typically help in neural communication and boost our immune system"

[@2FollowHim777]

Most excellent work. Why do they go bad and what if they do?

[@raghavagps]

Excellent lecture provide comprehensive information on exosomes

[@RogerWittekind]

Yes but if she knew the Covidexosomes contain mRNA she would have had a perfect example of how one cell sends another cell what it need to replace badly damaged DNA.

[@shahidiqbalworld6858]

Excellent

[@Mr4thetruth]

So Exosomes, which are identical to that which has been identified as Covid-19, are in fact quite normal part of the human body and constantly working to do us good. Therefore if Exosomes are good for us, then by definition so is Covid-19, QED. Long live Covid-19

[@emmanueltruths]

They're creating a vaccine to high Jack your exosomes.

[@alejandroarellano4277]

It is like cleaning our own body

[@serrazabot4963]

@@emmanueltruths sadly:(

[@emmanueltruths]

@@serrazabot4963 Thinking more about it, if they are highjacked. What will happen with all the poisonous water, air and food we consume daily? 🤔😳 If the cell can't clean itself, the cell dies.

[@serrazabot4963]

@@emmanueltruths ...i read "One Earth, One Humanity Vs. the 1%" by dr shiva well written book open my eyes , what happening is scary but there are bunch of good people fighting against , i do my own part to support them

[@adityapatel8156]

I am also working on exosomes involved in male fertility

[@hanfootball1367]

After watching this presentation, I think what Andrew Kaufman said that Covid-19 is actually exosomes is correct

[@RogerWittekind]

I fully agree that CV is an exosome because the cargo in the container is mRNA and prior to the CV outbreak there were DNA damaging events and cells with badly damaged DNA need mRNA to build brand new DNA via Reverse Transcription.

[@Memphis2010GFC]

@@RogerWittekind The RNA is exososmes is not the same as the RNA in the covid-19 virus. The covid-19 virus was isolated and its genome sequenced in early 2020. The RNA in the covid-19' virus is different to found in exosoes. each exosome within a cell will have different RNA fragments so the rNa content of each exosome is different!. Exosoem contains fragments of mRNA not the covid-19 viruses' RNA's sequence! TAn exsosoem dows not have the characteristic corona of the covid-19 virus!

[@RogerWittekind]

@@Memphis2010GFC If a cell request mRNA then a reply exosome will contain mRNA. Is that too simple for you?

[@Soshi701]

@@Memphis2010GFC Covid-19 was NOT isolated. Never. That is the problem.

[@Memphis2010GFC]

@@Soshi701 Please stop pushing disinformation. The virus was isolated very early on. How about doing some actual research instead of believing what you have read from some dodgy internet site. Do a search on these sites: I study viruses How our team isolated the new coronavirus to fight the global pandemic Isolation and rapid sharing of the 2019 novel coronavirus (SARS-CoV-2) from the first patient diagnosed with COVID-19 in Australia Lab that first isolated coronavirus in Australia shares how it was done The Covid-19 virus has been isolated many times The Covid-19 virus has been isolated many times The virus that causes COVID-19 exists and was identified and isolated multiple times by independent research groups

[@KarenSelickKAS]

Are exosomes a subset of redox signaling molecules, or is it the other way around?

[@Healthytarian]

If only scientists had the ability to consider all possibilities, rather than limiting themselves to one way of seeing things, which lead to giving the public the wrong ideas about the nature of health and disease. The "bad" exosomes are not malfunctioning; they are merely carrying the message of internal toxicity and, thus, disease conditions to inform other cells, which then respond in similar ways if susceptible.

[@mummys_boy_]

That was my first thought too. I think the scientists are often being guided to find ways to monetise their findings by creating pioneering new tools.. Jenner still being hailed a pioneer speaks volumes.

[@Jeph629]

1:30 During a Ted talk video it is---for some reason--important to always show/insert a clip of a well-dressed Asian woman who appears to be viewing the talk........(?)

[@jll1695]

We studies of Gaston Naessens and the microscope he inventer to observe what he calée somatides, or microzymas from Antoine Bechamps in 1870’s......

[@TSIXGaming]

and now we have sars2 maybe you shouldnt be splicing animal chimera and humans cells together with electron emitters

[@TSIXGaming]

the first electron emitters were built in the 18th century what array of frankestein experiments were conducted on living tissues to save lives they should have stuck to just washing their hands

[@jll1695]

They contain a silicium crystal.... memories of our computers are based on silicium

[@kunstkt]

There are also trace amounts of Boron in the human body, and Boron rhymes with moron. Coincidence? I think not!

[@shalinidatta1889]

Very lucid presentation

[@roberttaylor6577]

What happens when spittle and mud is rubbed into blind peoples eyes does the same process these people talk about apply to such a situation

[@SusanAllenDC]

Have you looked at a darkfield microscope to see if exosomes are visualized? I have seen small particles communicating but I am not exactly sure what they are...

[@salsacardone]

Darfield is only at the micron scale. 10^-6. These are nanoparticles. 10^-9, About the size of a virus, which requires EM microscopy. Since exosomes are fragile, EM destroys them.

[@JuttaEire]

Ein Kommentar: After watching this presentation, I think what Andrew Kaufman said that Covid-19 is actually exosomes is correct. Der Schlusssatz von Shivani Sharma ist: wir müssen das weiter erforschen für unsere Zukunft und die Zukunft unserer Kinder. Ich denke das ist der falsche Ansatz. Das ist nur Schadensbegrenzung, wir müssen herausfinden was den Körper veranlasst so zu reagieren - Giftstoffe? Umweltgifte? Also back to the roots!!!! Also Forschung warum macht der Körper das!!! Das ist der vernünftige Ansatz!!!

[@karmartdave]

"Their Precious Cargo"

[@mayamachine]

These would be susceptible to quantum effects

[@y2kazan868]

CoNviD 1984 is an Exosome.

[@Soshi701]

Yes

[@partheev9178]

Exosomes are providing a world of benefits in the area of hair restoration. Early indications suggest that exosomes are even causing hair folicales to regenerate in areas which have been bald for years.

[@georgeR3Roadster]

for me it all depends on our INTENTIONS !!! we are spiritual beings in a body of matter and we can and MUST MASTER our body !! too much people are not conscious of the fact that they are the "directors" of their body functioning !!! they are just passiv and undergo their health or sickness .... but our INTENTIONS give orders to our body cells to be the way we want it to be : sick or healthy !! just the same with our emotional life : happy or depressiv ..... 80 % of the people are not conscious about their mastering capability of their body !!! I once did read an article about the fact that if you, as a man, wanted to have good muscles you "just" had to think about having them and wanting them in a very big intention move while otherwise living a healthy life of course !! there must be harmony in all our intentions, no contradictions of course !!! Exosomes help us to pass the good info into our body !

[@sinweiy]

are exosomes transmissible? human to human transmission?

[@Storielle]

No

[@concussionoflight]

Exosomes are just as transmissible as viruses

[@sinweiy]

Levi Waldon really?

[@concussionoflight]

Wayne Yap as far as I understand from the reading I’ve done, the two are virtually indistinguishable

[@concussionoflight]

Wayne Yap but I’m not a scientist

[@mikewick77]

..

[@benwillard6751]

Our mental abilities as humans, could never fully comprehend how the body actually works. Its far too complex to understand, let alone "lecture" on anything but basic functions and structures. Any observations of functions that we can "accurately" understand are basic and rudimentary in comparison to functions such as exosomes. Discoveries we have made over the years have been as a result of complete accidental stumbling. Our bodies are microscopic universes and we have extremely little knowledge how the universe we live IN works, even less of the one living inside us. To see folks like this come out and "explain" how something like this works is frustrating to me as they are not qualified to speak and explain a subject THEY don't fully understand themselves. NO ONE is an expert at ANYTHING. There are those who may have more information than others, but that certainly doesn't make them an expert. All just speculation until 100% predictable and certain of the results. Good luck with that.

[@tarquineous]

We already know that, Ben.

[@Mr4thetruth]

Well said, I totally agree with you. The medical profession does nothing whatsoever for good health. They spend 5 years at medical school, memorising everything parrot fashion from their textbooks so as to regurgitate it out on exam day to get their esteemed qualifications. In that five years they learn nothing at all about nutrition and spend half a day learning about vaccines. The secret to health is a stress-free lifestyle, with exercise, good organic nutritious food and drink, clean air to breathe and clean water to drink. A good lifestyle will produce a strong immune system, the bodies survival mechanism which keeps us alive. Diseases occur when the body becomes toxic with the poisons we ingest, inhale, and absorb through our skins to say nothing of the vile cocktail of lethal toxic poisons that are pumped into tiny helpless babies bodies shortly after birth and onwards throughout our lives. Disease is a symptom of a body trying to detox itself. this is the function of exosomes (another name for a virus) in our bodies.

[@asher6679]

@@Mr4thetruth We have to understand it takes one great mind...we do all this to nurture an environment where 1 person can rise to make the difference...the more we support the better our odds.

[@georgeR3Roadster]

I completely agree !! those actual transhumanist scientists (especially bigpharma who only thinks about greed big profits $$$$ !!) think they are themselves "gods" .... they are arrogant and pretentious, proud and so they are satan's puppets ... satan is the max proud against God !! The Creation is so fantastic we never will understand it in this material life, not even in spiritual life !! but we can tend to !! that is the challenge !! namaste !!

[@kunstkt]

Please go to your local library and pick up a book on molecular biology. Flip to the chapter on the energy systems of the cell (which I'm hoping you will vaguely remember from high school) and tell me what knowledge is "missing" there. We KNOW in detail how cells manage some things and there are others we don't. But the methods and tools are only ~100 years old, and unfortunately there are many more morons in the world than scientists working on this stuff. What are you going on about "too complex"?

[@dallyjacobson2146]

You have to admit our Creator is very very intelligent, smart and beyond understanding. Is that why most scientists don't believe in Him. I am sure if scientists came to the Creator, Jesus Christ, by Faith, understanding the human body would become clearer.

[@hans_____]

Yes. Science is the discovery of everything God has made.

[@georgeR3Roadster]

I completely agree !! those actual transhumanist scientists (especially bigpharma who only thinks about greed big profits $$$$ !!) think they are themselves "gods" .... they are arrogant and pretentious, proud and so they are satan's puppets ... satan is the max proud against God !! The Creation is so fantastic we never will understand it in this material life, not even in spiritual life !! but we can tend to !! that is the challenge !! namaste !!

[@stephenjacobsen4616]

Not legit

[@cesarcdx]

Doctor Butcher.

[@breakage959]

lol

[@keithrichard391]

The real Butchers are the Docs who just want to prescribe drugs and operate with a knife:)

[@CH-jc4bg]

It seems fake though

[@kemchobhenchod]

It's not tho. Keep researching, you'll see.

[@CH-jc4bg]

OO

[@tarquineous]

You were not following, CH.

[@lavarelap]

🤦

[@CH-jc4bg]

💩

[@MediaBuster]

That accent is hard to listen to.

[@Mr4thetruth]

Turn on the sub-titles?

[@S7evin13]

can u speak her native language?

[@knickandchester]

She should get rid of her accent

[@georgeR3Roadster]

everybody has a accent, you are not perfect also ... ppffff ..... superficial blabla !