Expanded Stem Cells Vs Unexpanded Stem Cells: What Should You Choose?

[@deanparipoush812]

Dr. Kong what is your opinion of Dr. Adeel Khan's work on MUSE STEM CELLS?

[@robertciancio3239]

Great question. Hope to see her answer.

[@Thinkaboutit84]

I appreciate the detailed explanation. Listening to your presentation, I realized that the initial source and unexpanded purity are crucial for optimal results. Your passionate outline clarifies that you've explored various aspects of this essential health treatment.

[@JoyKongMD]

Thank you so much! Truly appreciate your comment and your support of my work.

[@studentfoevamo]

There is a road to wisdom and I applaud all who stay on the path

[@SageJolene-m2h]

I appreciate your dedication to making stem cell education accessible to everyone! On a couple of the general stem cell discussion groups, reaction to sc treatment had been discussed. This included the very situation you mentioned where the first treatment went well but not the second treatment. One speculation for the potential cause was a reaction to the blood cells if the donor and recipient were not matches for blood types. This was stated given that a small amout of blood cells are allowed to be in MSC's. How likely do you think that would be? I was wondering if the cord blood used would present any issue given it is blood but not cultured and as you stated less likely to show surface markers. Have you ever seen any similar reactions at your clinic with an inflammatory or immune response to a treatment and/or a reaction to the second or third treatment? Thanks again for providing clarity to a topic that is so murky.

[@JoyKongMD]

Blood type is one issue, but there are a lot more HLA markers or other antigens a cell can express that can cause issues. At our clinic, because we use young native cells, I have never seen an inflammatory reaction, even at second, third, and fourth treatment, etc..

[@SageJolene-m2h]

​@@JoyKongMDThat's great to know. Thank you.

[@Gmanproduction]

Great explanation Dr Kong! Very clear and easy to understand!🎉

[@JoyKongMD]

Thank you for your feedback!:)

[@chasegregory4522]

I just found your channel. I've been watching a few videos. Very informative. Thank you. Question: it is my understanding that our stem cells go dormant as we get older. Do any of your treatments activate dormant stem cells?

[@JoyKongMD]

Thank you for your comment. We do use supplements and laser technology to help activate stem cells, along with the young stem cells we give patients... The cells are less and less active as a person ages, not to mention accumulating replication error and genetic changes...

[@kyszre]

Thank you! Hope you continue to create more content, it's very helpful and appreciated.

[@JoyKongMD]

So glad to hear!!!

[@robertciancio3239]

Great explanation Dr Kong. What type of stem cell treatment would you suggest for a budging or Herniated disk?

[@JoyKongMD]

Thank you for your comment Robert. I would recommend both IV and local injection to help reduce inflammation and promote healing.

[@robertciancio3239]

@@JoyKongMD I’ll reach out to your clinic for more information. Grazie!

[@jefferyjeffery1707]

Yes...!! When stem cells are expanded/activated. Time becomes a very important factor to consider. Because they start gaining functions. Thatt the original syem cell parent....didn't have. This Gain Of Function...is the part that cancer cells...into becoming deadly... Metastaic Cancer cells. As cancer cellls under hypoxic conditions. Revert themselvres back to become Mesenchymal Stem Cells...and they then gain functioons. Jefferry...⚘️

[@KdubtheAxe2]

Help Dr Kong thank you for the valuable information. Is it possible to post the links to the sources of the research

[@JoyKongMD]

The sources are on the presentation and you can look up on your own easily:)

[@mattherdpodiatry]

Love your content Dr Joy. Are you able to elaborate on the immunogenicity part though? From my lay-man understanding, when the cells are harvested/collected there are multiple cell types including the likes of red blood cells and white blood cells etc. These all have surface antigens present and hence have the potential to create a greater immune response. The reason for expanding the culture is to not only increase the cell numbers but to also purify and remove the unwanted cell types so you are left with only MSCs.Typically this takes til passage 3 from what I understand. If you use unexpanded/native cells, wont this have a strong immune reaction because of the other cells present? How do you create a native unexpanded sample for therapy?

[@JoyKongMD]

The product we used (native cells) do not contain these cell types that can cause immune reactions. When companies "expand" the cells, they start with homogeneous populations of MSCs, and the expansion process is not to weed out the wanted cell types, but to get A LOT of MSCs. Unfortunately, during this process, immunogenicity can happens because of genetic expression changes and emergence of new surface markers.

[@JoyKongMD]

Glad you enjoy the content I put out. Just to clarify, the native cells we use at our clinic do not contain red blood cells or white blood cells. They are a mixture of primitive immune cells, fibroblasts, endothelial progenitor cells, and MSCs... all are considered stem cells, all valuable in their own right for the healing process.

[@joejuliani1]

Great Information

[@JoyKongMD]

Thank you!

[@propheticpig868]

Very very informative video! Thank you Dr. Kong. Question - I live in Vegas, but want to come to your clinic in L.A. to get the same MSC treatments you do. What is the best way to contact your office?? By phone call ? Or Email ? Thanks.

[@northshoreplaid]

Go to the website..and you'll schedule a call with one of the doctors at the clinic. Very helpful!!

[@JoyKongMD]

Glad you found it helpful. Would love to help you. You can contact our clinic at 818-356-8232 or email [e-mail]. You can also send in a contact form at www.joykongmd.com/contact/.

[@jeffgadbois1707]

Thank You For Your Time And Knowledge 💯🤝

[@JoyKongMD]

You're very welcome!

[@Peetie_Wheatstraw]

Excellent information Dr Kong! I was wondering if you can talk about exosome therapy vs stem cell therapy, and what each is used for, if there is a preference for one over the other in certain circumstances.

[@JoyKongMD]

Thank you! I made this video a while ago explaining the differences between these 2 regenerative therapies: Stem cells vs Exosomes kzbin.info/www/bejne/hXbXiJyLn6yjlcUsi=k5YOwBrdZYCEQWv_ Hope you find it helpful.

[@Peetie_Wheatstraw]

@@JoyKongMD I checked it out and you explained everything very clearly. Thanks!

[@jlvandat69]

Just beginning to learn about Stem Cell Therapy and appreciate the information. I'm open to any intervention that has a positive effect on health and/or longevity and see SCT has the most natural unnatural intervention, if that makes sense. I'll keep doing homework.

[@JoyKongMD]

Wonderful. I have many lectures on KZbin. You will find this helpful: ‪Stem Cell Therapy as An Antiaging Tool‬ kzbin.info/www/bejne/m6uaq4iJr62ii9k

[@gh4534]

Hi Dr. Do you know that the Mayo Clinic is using a microwave size device to extract the patient's own stem cells and the patient can receive an injection on the same day of their own stem cells? No risk of rejection. (But I'm not a doctor so my explanation is limited.) It was invented by a company located in Vancouver, Canada.

[@JoyKongMD]

Yes, we can certainly use a patient's own Stem Cells for therapy. However, there are various concerns I have regarding sourcing cells from a person's own body. I have made comparisons between using a persons own stem cells versus using young stem cell sources, such as the umbilical cord. Please watch this video of mine for details: Are All MSCs Created Equal? ‪kzbin.info/www/bejne/laTVoKGafrqpd6s‬

[@dorisenga4701]

Thanks much for this education.

[@JoyKongMD]

You're very welcome.

[@ryanknowledge]

how can you know forsure that cultured stem cells are worse? have you gotten cultured stem cells yourself dr. kong to see what results are?

[@JoyKongMD]

Again, my goal is to present evidence to the public. I have seen patients who have received culture cells overseas with significant side effects, and they did dramatically better with native and unexpanded cells at our clinic. I myself do not object to trying expanded cells myself, but I am concerned about the potential side effects.

[@bobshoaf36]

Have you investigated Lifewave stem cell patches, which are very very cost-effective and they work.

[@JoyKongMD]

Unfortunately for people who actually used the product, I haven't heard anyone saying it helped them. I am not convinced of their science yet.

[@rothclaudia9948]

Dear Dr.Kong, I am living in Europe (Germany) can you recommend anybody here around who offers similar experience, quality and service like in your clinic?

[@JoyKongMD]

Unfortunately I don't know anyone in Europe when it comes to stem cell therapy...

[@rothclaudia9948]

Thank you for your Feed back Dr.Kong. What about Asia ? Korea or Thailand? Habe a Beautiful Day Claudia

[@claythomas359]

Are the birth tissue stem cells kept frozen until use and do they degrade while frozen?

[@JoyKongMD]

Cells were cryopreserved and thawed right before given to patients. When processed correctly, often 85-95% of the cells will still be alive after thaw.

[@claythomas359]

@JoyKongMD thankyou for the reply

[@jaybok100]

Dr Kong I experienced wide spread subcutaneous fat loss due to an illness. Can stem cells become fat cells if required?

[@JoyKongMD]

MSCs do have the potential to become fat cells, how much of the differentiation would happen I am not sure... May not be significant enough, depending on the degree of your fat loss. Fat grafting may be a good approach in that case, but you can always add MSCs to enhance the survival of fat cells after transplant...

[@jaybok100]

Thanks Dr I became sick due to Botox poisoning and also have symptoms like sensitive CNS, tinnitus, exercise intolerance and some autoimmunity. Do you think SCT would be a good fit for me? I'm trying HBOT next but if that doesn't work stem cells are next on my list to try

[@Sleepdriver1984]

​@@jaybok100 meanwhile, you'd benefit to an extent (while not expecting miracles, of course) from daily oral supplementation with higher dosages of cholecalciferol, carnitine, creatine, L-methylfolate, methylcobalamine, calcium D-glucarate, serrapeptase, PEA, nervonic acid, GABA, delphinidin, alpha-lipoic acid, PQQ, pycnogenol, ubiquinol, DHA fatty acids and trans-resveratrol

[@stephenantonicelli7069]

Has FDA approved Stem Cell Thearpy in US? COST

[@JoyKongMD]

The only FDA indication for Stem Cell Therapy is for Hemo-reconstitution purposes in patients with blood cancer or autoimmune diseases who have had their own immune system wiped out through chemotherapy.

[@JoyKongMD]

As to the cost of stem cell therapy, it is based on dosage of cells needed, which is determined by a person's bodyweight, age, and health issues, as well as considerations such as whether local injections is necessary in addition to IV infusions. Generally, treatment cost for most people ranges between $8500-$18,000 per treatment. If you want to understand a little bit more about what goes into these costs, this video of mine on KZbin may be helpful: Cost of Stem Cell Therapy kzbin.info/www/bejne/omTRd3Sqfcekr6ssi=L6GSn2M009oa0eeZ

[@studentfoevamo]

All cells have a connection to time.

[@JoaquinDeLucas]

If expanding stemcells were allowed in the United States would you still be against using duplicated cells for therapy?

[@JoyKongMD]

I would have to examine the technology very carefully and check the offspring cells for changes in generic expressions and the culture medium for inflammatory signaling molecules... Not all processes are the same. Because we are getting such extraordinary results at our clinic with a fraction of the number of cells used, there's really no burning desire on my part to use expanded cells. But I am always open to new and better ways of doing things, as long as it brings further benefits to my patients with minimal side effects.

[@ricruffini4381]

So when you state around minute 7….. Bone marrow cells and expanded MSCs are equal in results given the numbers difference….. They are again equal

[@JoyKongMD]

Please watch this video where I laid out scientific studies showing why they are not equal: Are All MSCs Created Equal? ‪kzbin.info/www/bejne/laTVoKGafrqpd6s‬

[@faithfahnbulleh5927]

Hello can your clinic treat a child with autism

[@JoyKongMD]

Yes, we have been treating a lot of children with autism. Next week I will publish the lecture I gave at a large autism conference in Brazil a few weeks ago.

[@Hercules-yl2yx]

😊 You seem to know stem cells very well. Call them up and tell them that I need their help 😂.

[@ryanknowledge]

also, it's convenient you left out the fact that it's illegal to culture stem cells in the US. so you are just building your narrative of why your way is better

[@JoyKongMD]

Culturing stem cells is not illegal in itself in the US, but the cells cannot be administered into a human without the person been enrolled in a clinical study that's registered with the FDA. Please watch this video where I presented studies explaining the issues with cell expansion. The goal is to educate the public existing scientific evidence.

[@iansuncoast]

Any relation to King Kong ?