Exploring the utility of stem cell therapy | Peter Attia & Adam Cohen

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This clip is from episode #264 ‒ Hip, knee, ankle, and foot: diagnosis, treatment, and surgery of the lower extremities | Adam Cohen, M.D.
In this episode, Peter is joined by Adam Cohen, an orthopedic surgeon with expertise in sports medicine.
In this clip, we discuss:
- What are stem cells
- The role of stem cells in modern medicine
- Cortisone injections
- Randomized control trials looking at PRP
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About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 60 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
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[@JosephMcCaffrey-m2k]

Quite disappointing that your questions on stem cell therapy were largely ignored and answered with words to the effect of “the FDA doesn’t allow it”. Fine, that’s certainly a fact worth noting, but there is no reason not to explain the actual research literature

[@jameszeris5418]

Oh yeah the FDA they’re looking out for us they when it was plenty of evidence that ivermectin works, and now their peer reviewed studies she talk to Cory Doctors’ zalenco anyway I think the FDA’s a corrupt institution, and I don’t give a damn about the people just profits

[@MarceloOleas]

exactly how I felt

[@Theta63]

Exactly 💯 Cohen has no idea. Stem Cells do work

[@jameszeris5418]

Yes it works FDA CORRUPT MY FIANCÉ MUCH IMPROVED LIVER CYROCIS

[@mrrptube]

Was just about to say this lol. Hopefully peters team gets someone else on here with a broader scope of discussion than "well the FDA..."

[@MichaelB1979]

6 minutes in and Im thinking this guy works for the FDA

[@Nickilt]

Yeah, he's a joke!

[@kapn33]

Adam basically dodged the most interesting questions, which are about actual stem cell therapies such as using Wharton’s jelly. PRP is old news. Just because the fda doesn’t currently approve of something doesn’t mean we shouldn’t discuss it.

[@robdoubleyou4918]

Yeah, he was embarrassingly evasive.

[@MarceloOleas]

completely agree

[@reverseaging5387]

im disappointed that Dr Attia has chosen a hack for big pharma as a guest ....

[@constantineberryman4968]

The American medical establishment isn't in the business of healing people, they're in the business of making money. Stem cell therapy denies them of repeat customers.

[@ZoltanSzemak2]

Akso they do not talk about the embilical cord stem cells

[@denisesmith9401]

I had stem cell therapy in Mexico for Parkinson’s and it helped! This is exactly why our country is so far off! He’s a surgeon so of course he’ll sway the other way!!

[@byankabarajas4087]

Where did you go? Did they inject actual stem cells?

[@mytube785]

Surgeons can’t treat Parkinson’s 😂😂

[@cameronfous]

They literally didn’t even talk about stem cell therapy at all. Just deflected the question. Peter get someone on who can actually talk about this topic please :)

[@TheAllanBrownlie]

Agreed!

[@MarceloOleas]

Exactly!

[@juliemclaren2981]

He should get someone with something useful to convey, like Dr. Adeel Khan who was on the Jordan B. Peterson podcast.

[@PhilosophyofArtandScience]

Mel Gibson

[@sophiebader8966]

Platelet-rich plasma (PRP) is not a stem cell therapy itself. PRP involves drawing a small amount of the patient's blood, processing it to concentrate the platelets, and then injecting this plasma with a higher concentration of platelets into the affected area to promote healing. While PRP contains growth factors that can stimulate tissue repair, it does not introduce stem cells directly. Stem cell therapies, on the other hand, involve the use of stem cells to regenerate or repair damaged tissues.

[@joemoya9743]

I believe the reason there is so many mixed messages with stem cell therapy is because there are so many moving parts in this treatment. The variety of experienced among physicians and concentration methods is so varied it is to the point that even if you had patients with the exact medical issue and same genetic make-up (which is impossible) were treated "exactly" (used loosely) the same, I feel certain you would get different outcomes because the patient themselves could inadvertently add or lower value to the treatment by the different levels of disciplined to physical therapy associated with injuries. Personally, I have had 2 such PRP plus Bone Marrow Concentrate (or stem-cell) injections (knee and one shoulder). All have been successful. This is true compared to traditional surgery used to treat one shoulder for a radial tear and the other shoulder (also with a radial tear) was treated with PRP plus Stem-cell injections. Fast forward 3 yrs. later, I have had better results with the PRP plus stem-cell injection, BUT, the traditional surgery also showed good results but was slower to recover and left me with a small loss of mobility. For reference, I am 66 yr. old with a life long history of being extremely active in IM level triathlons.

[@xzx3]

That's great! I might ask my surgeon about PRP for rotator cuff full tear. Also may I ask, how much is the loss of mobility on your shoulder affecting you. I have superior flexibility despite tear and have done yoga for 46 years just don't want to lose flexibility with shoulder surgery.

[@joemoya9743]

@@xzx3 The only suggestion I would make with regard to PRP treatment is that you should choose a doctor who specializes in such treatment. There is an art to the injections that can only be gained through experience. Also, it is not as simple as separating the plasma from the red blood cells with a centrifuge. The more advance methods also use filtration. The only clinics that I know do this are specialized clinics. You can tell the difference in how the PRP looks. The more clear-like the PRP the more likely to be effective (at least that is what I was told). But, quality of PRP did make a difference in my experiences since I have also used PRP treatments for stenosis in my neck. In my instance, I found my doctor by calling numerous sport trainers at various D1 Universities and Profession Football teams. While I did get a lot of "no-answers", I did find some to be VERY helpful in providing me with doctor references. Also, I learned a lot of first hand explanations and experiences with athletes with regard to PRP treatment and stem-cell injection. Primary of which is this: Use experienced doctors. Use specialists. Use only bone marrow source. Use PRP and Stem-cell in combination. Finally, and MOST IMPORTANT, follow through with long-term physical therapy is crucial to any success. PRP plus Stem-cell injections are not a single source of magic. Without LONG TERM and consistent physical therapy you reduce the chance of any treatment working. This is especially true with PRP and Stem-Cell injections. The success rate is determined more by commitment of the patient to maintain PT activity (...think at least 1 yr. or more in some instance) and not simply the younger you are the greater the chance of success. In fact, a 65 yr. old highly motivated and committed active adult will more likely gain the full benefits of PRP and Stem-cell treatments than a 25 yr. old couch potato. While age gives an advantage, it is commitment to years of methodical physical therapy that provides the greatest value added to PRP and stem-cell treatments.

[@mytube785]

Is there an update podcast on Stem Cell Therapy, with coverages of latest scientific medical publications? It is so limiting to only US authorized uses of Stem Cell Therapy

[@Hear4thescience]

Change the title of this video to prp

[@psmith4980]

It's bait and switch, typical of youtube.

[@liveandletlive3322]

Simply put. Stem cell therapy saved a friend who was near death from diabetes. In a wheelchair he went to Mexico and he is now living a normal life. These two doctors closed mindedness has caused many to die and suffer unnecessarily! I am not saying stem cell is a cure all.

[@andrewjrussell5100]

Peter, the gentleman speaking is utterly unqualified to speak in stem cells. He didn’t even describe the composition properly. Speak with Neil Riordan, Roberta Shapiro or Eric Stoffer if you want to disseminate proper and insightful facts. This gentleman - no offense- is not fully educated on the subject matter of stem cells. PRP is far off from mesachymal stem cells. And he couldn’t even differentiate for the audience

[@xzx3]

Don't know about the stem cell therapy but in 2009 or 10 I had PRP on semi membranosus - tear from many years of consistent running causing all sorts of pain. Worked beautifully, I didn't run as much thereafter but about 5-10km at a time was ok. But now again since last year the pain came on but nothing as bad. The same doctor now said, we don't do that anymore cos the medical world says it doesn't work. Worked very well for me for 12 years out could do active sports.

[@Davidsample7761]

Peter. You asked the right question. What about the stem cell therapy in Mexico. Cohen didn’t know anything about it. Find another expert.

[@mileseverson7323]

Peter. You need to find a real expert. His definition of stem cell therapy is very narrow. He is not knowledgeable on other treatments. Check out Stemaid Institute , Las Cabo, Mexico. Very strong results of success with immune system disease.

[@rajgovindarajah8282]

I hope Dr Peter Attia invites Dr Joy Kong - let her explain stem cell therapy that she is doing right here in USA. I enjoyed watching her explanation including commentary on Life Force book that Tony Robbins is referring to stem cells.

[@ssharp8900]

I am loving this series, Peter. I have a condition called EDS and have used prolotherapy on chronic pain/injured areas with the faulty collagen my body produces and the inflammation response and hopefully result of my body laying down some more tissue has been so very successful! Obviously I have altered my lifestyle, diet and supplements since getting my Dx but this regeneration therapy has been amazing (that being said, I did surgery on my thumb arthritis because I read there is NO way to produce more cartilage with PRP, or at least not as much as my body would need to heal the joint....and surgery was the correct choice for me as I am back to pain free on that joint -- my surgeon used sutures instead of tendon transfer). I would love (selfishly) a deep dive on EDS or connective tissue disorders (if you are taking requests....LOL). Thanks for all you do!

[@jessiemoreno1260]

Who is this from fool mesenchymal stem cells from umbilical cord work. See stem cell institute in Panama

[@robbmorris7790]

There's no sustainable profit in the "Cure". There is in the ongoing "treatment". Until we reconcile this, there will always be push-back on progress. The good news is "push-back" has a shelf life. In the end, progress always wins.

[@Test-eb9bj]

I appreciate that Adam Cohen speaks in a voice of caution - still acknowledging that PRP shows good results regarding mitigating symptoms. I was very sceptical if such thing would work but have to say it seemed to help in my cases of golfer-arm syndrome. Tendons on both sides were affected severely at the same time. I started treating one arm with injection and it did become significantly better within 4 weeks whereas the other arm stayed more or less the same. Took a second injection and it continued to get better. The untreated arm meanwhile got slightly better too but the difference was very noticeable. After three months both arms are far away from being healed but they still seem to get better on their own. The one arm with one treatment less than the other is still behind at this point so I might go back for a last injection.

[@zibtihaj3213]

What about prp for skin rejuvenation ?

[@littlevoice_11]

PRF seems more effective for skin

[@MicheleLee-fe2ob]

What are your thoughts on LifeWave X39 and X49 stem cell activation patches?

[@littlevoice_11]

I hope you cover red light therapy for joints

[@GrowthGreg]

I had a spinal cord injury and had tremendous success with fetal stem cells in Mexico. Met tons of other people with various conditions massively improved or cured by stem cells, but he says they don’t even exist?? What the hell else could cause all the miraculous testimonies???

[@douglasbooth6836]

Not watched the video yet but I know a few athletes especially older ones are raving about stem cell treatments.

[@fight9896]

So what the hell is the reason for making this clip? to tell me it’s now allowed?

[@treykilgoreiscool]

The problem with stem cell therapy is the moral arguments that this guy beat around the bush the whole time about

[@mytube785]

The title of this video clip should be changed to “We don’t know anything about Stem Cell Therapy beside for leukemia in the US” 😂😂. How ridiculous is it that FDA hinders Stem Cell research and applications?!

[@JohnSmith-tv3ue]

Thank you.

[@SallySamsara]

Please interview a physician from, say, Mexico, Panama, or Costa Rica who is an expert on this topic, vs an American doc who doesn't use stem cells, and who is vague and evasive. Are USA ortho surgeons afraid stem cell therapy will replace their surgeries?

[@thomasemanualichim]

Fda allows us to use stem cells under Right to Try

[@deejays93]

Now I'm really confused!

[@rodrigosepulveda4559]

This doctor only knows what is legal in the US doens't know what is legal in Mexico and other parts of the world, so the stem treatment is real and that is what we would like to hear, an expert opinion on what is going on abroad and gettting this therapy done outside of the US. What is your opinion on the subject?

[@constantineberryman4968]

He said it's "not real stem cell therapy outside of the US either." He knows exactly whats going on outside of the US but he's not allowed to talk about it because of whatever Pharma companies he's in bed with.

[@liveandletlive3322]

These same doctors still say you don’t need to take vitamins and other supplements. How women developed breast cancer because they have been extremely deficient in vitamin d for many years?

[@jul059]

What’s that clinic in Mexico?

[@constantineberryman4968]

Cellular Performance Institute in Tijuana

[@MrJaimerr09]

Why is he not giving credit to Regenexx getting bone marrow stem cells and working with that

[@anitadai6143]

I love your videos, thank you

[@lynnemarie2022]

What do you think of PRP used in plastic surgery and to regrow hair??

[@sunnykgaming2541]

the fact that he referenced the cdc I already seen all i need t osee.

[@lookswhatsnew8951]

Wharton Jelly MFC contain stem cells

[@Robsamuel]

BPC probably better route to go

[@beronicad.2580]

What's your thoughts on stem cell and autism?

[@rhiannatibbetts4968]

So my question is how many children with cerebral palsy have you seen get saline injected into them and start to talk because I don’t think that’s possible and how much are these drug companies paying you to make sure that they’re interests are not compromised

[@riceexperiment]

This is such a great conversation. I had an acquaintance that really had a bad experience with "stem cells" injected.

[@benrushing4041]

Please elaborate. Where was the procedure done, what were some negative effects? Thanks

[@cutcokanarick6115]

What did she have done and where?

[@kevinswaney5875]

13:28 It seems odd he avoided talking about stem cells unless he has his own practice in the US which doesn't allow using stem cells?

[@hotbutterwell194]

FDA unfortunately works for corporate interests not us plebs.

[@onlybryanliu]

Skip the vid. The guy ain’t talking

[@a1osborne]

This guy is doing the lord's work. Bravo.

[@Thedogfather209]

FDA doesn’t oversee Mexico tho

[@kib9749]

FDA=obstacle to progress

[@sunnykgaming2541]

is peter attia interviewing peter attia ?

[@constantineberryman4968]

I LOLed so hard at this. Peter does the exact same shit and is in bed with the statin companies.

[@joemagicdeveloper]

another example of Doctors resisting the new wave of technology.

[@seniora_jendy8914]

FDA approves all sugar, cancer related food, medicine, etc.....WONT APPROVE WHAT ACTUALLY CURES US.....😂😂😂😂

[@jimywealth4628]

There is def stem cell therapy and it works. What stone-age is he speaking from? Very confusing

[@georgegray2712]

Please provide meta-analysis level evidence. Because everything I’ve read says the results are inconclusive. Don’t provide single studies or your personal opinion or anecdotes; provide systematic review or meta-analysis level evidence.

[@jimywealth4628]

@@georgegray2712just described SSRI's and yet...

[@riceexperiment]

He was talking about none are FDA approved. Stem cells can actually be problematic.

[@georgegray2712]

@@jimywealth4628 Don’t change the subject. Please provide evidence at systematic review or meta-analysis quality that stem cells are effective. Otherwise it’s just your opinion they’re effective based on limited reasoning and anecdotes.

[@joseinjin1028]

just type mscs stem cell meta analysis and you will find “your evidence”….mesenchymal stem cells have been used for years in various studies and proved effective and safe. You can get treatment outside the US and Canada only. stem cell treatment is not allowed in the US as far as i know but you can fly to places such as Dubai and get 100million plus cells.

[@stevengraham3138]

First 5 min nothing I did not already knw

[@gilkennedy7638]

Its frustrating to see how he dodge the question about what they are doing in Mexico when people don't feel the pain in their shoulder after treatment, please get somebody else that would talk about that.....

[@cedarxeda2665]

Speaks like this dude is confused

[@twoheartshomesforseniors]

My wife got PRP about 6 months in her tennis elbow and it didnt help at all, like zero. She got the tennis elbow surgery and 2 months later shes almost perfect. For some reason, I trust every doctor that Peter brings on, I found it funny though that the first thing he said that PRP helps is tennis elbow.

[@loopba]

Disappointing, fine to cover the RCT evidence and go further on the actual biological plausibility, next steps in regenerative medicine, etc

[@da_gosher2897]

Go to mexico

[@DeanKilby]

This a very ill informed (on the scientific and regulatory fronts) and incredibly biased. Wouldn’t expect anything less though from an orthopedic surgeon. Peter, you need to interview the likes of Drs Chris Centeno, Don Buford, Allan Mishra, Steve Sampson, Peter Everts. Or even Neil Riordan.

[@millertiiime1]

Of course the fda won’t allow it because it actually works !

[@jssmc73]

Anyone with experience with Stem cells, I'd love to hear you feedback please. Thank you!!!

[@riceexperiment]

Lots of sketchy clinics only in it for the money. That's the issue.

[@mikecaprock9684]

Losing faith in US medicine and science in general. Know people that that have been helped going to Panama , Mexico and the far east . Is it a cure all no. Some get little to no help . Do your own research .

[@CIAYAHandAHRLIE]

This guy says there's no such thing as stem cells.Then later turns around and says it's illegal to use real stem cells. Lol Fokes Go to CPI in Mexico!

[@DouglasBouldin]

This guy is the typical medical provider who thinks surgical solutions hold the best outcomes, I found his opinions to be poorly supported and its quite clear he is not educated on the most recent literature. Let alone the overreaching ability he credits the FDA with.

[@bighawk1h]

Oh the FDA... Lol

[@susanauchincloss4990]

Very disappointing discussion

[@barrymc10]

Another doctor that can’t think for himself and won’t listen to patients. If it’s not in JAMA, approved by the FDA or has multiple studies he’s not onboard. Lame!

[@Notourtube]

What a bs interview

[@tomchristian9932]

How about teaching, diet, lifestyle and exercise, which is at least 85% of the equation…. Keep inflammation down with diet!…….the rest???

[@b4bmm]

How compromised is this guy lol

[@kevinsutube1p528]

This guest sucks

[@bobmenacho]

Boooooooooooooring

[@allanpaulett5394]

Waste of time " stem cell therapy is illegal"