The Discovery of Insulin - The Miracle - Medical History - Extra History - Part 1

  Рет қаралды 362,065

Extra History

Extra History

2 жыл бұрын

If you live in Minnesota, learn more at U21checkups.com. If you don’t, check here: www.medicaid.gov/medicaid/ben...
Jan 19th 1922, University of Toronto. Day and night for 11 days James Collip has been in the lab preparing sample after sample of a hormone taken from beef pancreas. His team hopes this will save thousands of children a year but in truth, it's one specific child Collip is trying to save, and it's a race for the cure.
Follow John James Rikard Macleod, Frederick Banting, Charles Best, and James Collip in the discovery of insulin, a miracle cure.
Part One - The Miracle: • The Discovery of Insul...
Part Two- Free for All: • The Discovery of Insul...
___________
Support the people who make this show, vote for future Extra History topics and get great perks at our Patreon! bit.ly/EHPatreon
Subscribe & ! to our channel on KZbin at bit.ly/SubToEC
Got more info about Extra Credits on our website at extracredits.site/
Grab your Extra Credits gear at the store! extracredits.store/
Watch this episode ad-free at watchnebula.com/extracredits
___________
Thanks for participating in this week's discussion! We want you to be aware of our community posting guidelines so that we can have high-quality conversations: www.extracredits.site/extra-c...
Come chat with us live on Twitch bit.ly/ECtwitch
Want to contact us directly? Email us: contact@extra-credits.net
Interested in sponsoring an episode? Email us: extracredits@standard.tv
___________
Want more Extra Credits? Follow us on social media:
Twitter : bit.ly/ECTweet
Facebook : bit.ly/ECFBPage
Instagram : bit.ly/ECisonInstagram
___________
♪ Get the intro music here!
bit.ly/1EQA5N7
*Music by Demetori: bit.ly/1AaJG4H
♪ Outro Music: "Monopolies"
by: Tiffany Roman
#ExtraHistory #Insulin #MedicalHistory

Пікірлер: 755
@extrahistory
@extrahistory 2 жыл бұрын
If you live in Minnesota, learn more at U21checkups.com. If you don’t, check here: www.medicaid.gov/medicaid/benefits/epsdt/index.html
@thepoglin8479
@thepoglin8479 2 жыл бұрын
wait how is this post 2 days old?
@professorcube5104
@professorcube5104 2 жыл бұрын
@@thepoglin8479 it was privated
@Ceo_of_Noobs
@Ceo_of_Noobs 2 жыл бұрын
WASNT NICOLAE PAULESCU WHO DISCOVERD THE INSULIN
@brentgibson8198
@brentgibson8198 2 жыл бұрын
Wait you still didn’t finish the takeover of India series
@berkeleysmith6630
@berkeleysmith6630 2 жыл бұрын
A STORY ABOUT A CANADIAN LETS GOOO
@SpoopySquid
@SpoopySquid 2 жыл бұрын
"They resolved not to profit off this discovery" US pharmaceutical companies: I'll pretend I didn't hear that
@GiordanDiodato
@GiordanDiodato 2 жыл бұрын
@@scottanno8861 ok antisemite
@GiordanDiodato
@GiordanDiodato 2 жыл бұрын
if anything, I blame insurance not covering enough
@sbatou87
@sbatou87 2 жыл бұрын
It's not just insulin, but other drugs, too.
@wallywallendo
@wallywallendo 2 жыл бұрын
@@GiordanDiodato nope it’s pharma, and government refusal to advance along with the rest of the developed world with free healthcare.
@dallindespain4093
@dallindespain4093 2 жыл бұрын
Right now one vile of insulin costs about $100
@ShortHax
@ShortHax 2 жыл бұрын
The discovery was wonderful for the kids but imagine how the parents must have felt? Probably one of the greatest days of their lives. Imagine the dread they must have felt knowing their kid had what was basically a death sentence
@Sqk.
@Sqk. 2 жыл бұрын
Exactly.
@ProvidenceNL
@ProvidenceNL 2 жыл бұрын
I kinda choked up a bit at that part honestly.
@NewWaveEnthusiast
@NewWaveEnthusiast 2 жыл бұрын
Hello. Again.
@thundervaart
@thundervaart 2 жыл бұрын
2 years ago, at 24 years old, being 1.80 m tall weighing ca. 75 kg, I was diagnosed with Diabetes. Docs said basically since I'm not fat or old it's most likely type 1 Diabetes. About 1 week before the diagnosis, I weighed ca. 80 kg. In just one week I dropped 5 kg all the while eating like crazy, especially sugar (which was weird for me, since I wasn't that much of a sweets snacker), getting up every night to drink about 2 litres of water and piss about 6 times. Only at night, imagine the days. Also, I normally sleep through the night "in one sitting". I felt incredibly weak and weirdly hungry, my eyesight was extremely blurry and I was constantly in a daze. Sure, those parents probably had the greatest day of their lives, but those kids must have been through hell and beyond. Finally feeling energized, not having the urge to stuff yourself or drink water like you went through a desert for 3 days straight. Having hope not to die with your 10 years of age. I only felt symptoms for a couple of weeks, they suffered months or even years AND most likely felt responsible for their parents sadness. It's kind of macabre to say, but.. you "may always" have another kid, but these kids would never have another life (I know it's far more complex, hence quotation marks). I know what you wanna say and I'm not challenging you think otherwise, but getting handed back a chance at life as a "healthy human" is far more than just wonderful. Or at least, what I wanna say is, of course one shouldn't forget the parents, but I think those kids were the happiest on the days of their first injections. Then again, you might be a parent, I'm a guy with Diabetes, so no wonder I feel the kids should be the focus and not the parents. In the end, there's nothing wrong with your comment, this text is only a justification as to why I feel in disagreement with it. Guess it's too personal for me lol I'm just grateful I may live on, I can't imagine how utterly thankful those kids must have been. Have a nice day everyone!
@IcecreamMcGuy
@IcecreamMcGuy 2 жыл бұрын
Yeah
@jeffmcarthur5617
@jeffmcarthur5617 2 жыл бұрын
"The child is dying!" "Quick! Get him coffee and booze!"
@N00b0super
@N00b0super 2 жыл бұрын
Alcohol doesn't necessarily lower blood sugar, it's different for every person. I'm diabetic and my blood sugar may either get really high or really low whenever I get wasted even if I am carefully controlling it. And coffee is probably one of the worst things to give to someone with hyperglicemia: your heart may simply not withstand pumping thicker blood real fast (my heartrate when I have high blood sugar gets high even without coffee).
@hughGrant748
@hughGrant748 2 жыл бұрын
Booze
@laureneras9523
@laureneras9523 2 жыл бұрын
I mean what I want on my death bed. Lol
@Docwilson91
@Docwilson91 2 жыл бұрын
@@user-pj5wf3jm2u I would have thought the opposite for alcohol, since alcohol breaks down in to sugar.
@andrewenderfrost8161
@andrewenderfrost8161 2 жыл бұрын
@@Docwilson91 alcohol makes your blood sugar raise first, and then drop dangerously.
@19MAD95
@19MAD95 2 жыл бұрын
Nothing like a good fist fight to dissuade greed.
@notme8232
@notme8232 2 жыл бұрын
Someone needs to tell Banting about the drug market today, he'd probably physically manifest as the Doom Slayer
@robert-janthuis9927
@robert-janthuis9927 2 жыл бұрын
@@notme8232 Nah, we'd suddenly get treated to a real life vigilante, only known as Bantman.
@jordisaura6748
@jordisaura6748 2 жыл бұрын
often I feel tempted
@ecurewitz
@ecurewitz 2 жыл бұрын
these days greed is maximized
@fuzzyhair321
@fuzzyhair321 2 жыл бұрын
sir you have an option tell me or lets say broken bones will be made and you've got a lot of bones
@Eramiserasmus
@Eramiserasmus 2 жыл бұрын
This is always inspiring to think about. They closed in on something and have saved thousands of thousands of lives. Shame about it's price in the modern pharmacy.
@osonhouston
@osonhouston 2 жыл бұрын
Millions of lives and counting, myself included.
@DomyTheMad420
@DomyTheMad420 2 жыл бұрын
aaaaaaaaaaaaaaaaaaaaaaaaaaaahahahahahahaha you AMERICANS crack me up.
@killme9909
@killme9909 2 жыл бұрын
@@DomyTheMad420 hahahahaha, yeah we totaaaaally dont want free healthcare and the ability to get help without being in debt the rest of our live but neither goverment party will give us that. Yeah we want to be in debt, its our fault
@professorcube5104
@professorcube5104 2 жыл бұрын
@@DomyTheMad420 indeed, laugh at our suffering
@LillyP-xs5qe
@LillyP-xs5qe 2 жыл бұрын
Empathy and care made it possible. Capitalism made it inaccessible.
@smoche
@smoche 2 жыл бұрын
I can only imagine how Banting would feel seeing countless pharmaceutical companies benefit from something he felt was so essential to save human lives that he wouldn't patent it
@Demopans5990
@Demopans5990 2 жыл бұрын
Open source wasn't a thing back then. Think one of the first thing I would do is to hand him a Apache 3.0 license and a lawyer
@SuperNova-so2cj
@SuperNova-so2cj 2 жыл бұрын
maybe we should take notes as to how he convinced collip not to profit off it
@memesthatmakeyouwannadie3133
@memesthatmakeyouwannadie3133 Жыл бұрын
Go ham on them like he went on Collip. Probably be proud of Canada for not succumbing to greed and ensuring everyone who needs it can get it for free/cheap.
@laurakastrup
@laurakastrup Жыл бұрын
My man would have gone to big pharma personally and beat someone’s ass.
@nicholasarmstrong643
@nicholasarmstrong643 3 ай бұрын
Type 1, I don't know if I feel anything is simultaneously as evil and prevalent as charging people money for life sustaining medicine.
@hardhatlunchpal
@hardhatlunchpal 2 жыл бұрын
There is something very heartwarming about hearing that they rushed to the diabetic ward and injected the children with insulin that clearly saved their lives. It reminds me of a CBS Sunday Morning episode that's just all of a sudden tearing at your heart.
@Lazarus1095
@Lazarus1095 2 жыл бұрын
I admire Banting's response to the standard practices of the modern pharmaceutical industry. We could use a few more guys like him.
@IcecreamMcGuy
@IcecreamMcGuy 2 жыл бұрын
@@Lazarus1095 it wasn’t only Banting though he had a humongous part in it
@MerkhVision
@MerkhVision 2 жыл бұрын
@@IcecreamMcGuy I think they’re talking about his anti-greed stance, not his overall contributions to the project.
@ShankarSivarajan
@ShankarSivarajan 2 жыл бұрын
If you this that's admirable (as you should), then you'd be the most despicable sort of hypocrite if you support the FDA preventing people from getting access to medicine they want.
@Lazarus1095
@Lazarus1095 2 жыл бұрын
@@ShankarSivarajan Um, no, that doesn't follow. The FDA prevents drugs that don't work or that have catastrophic side effects from going onto the market. Thalidomide is the classic example. Did you mean the Patent Office?
@John-Ginger
@John-Ginger 2 жыл бұрын
Imagine the euphoria in the room with the six comatose kids, with the first starting to wake up within a short period of time. The knowledge that it worked and wasn't a fluke and that it will change the world.
@basoon87
@basoon87 2 жыл бұрын
Good for Banting. I'd have knocked out that guy too for suggesting he would patent the purification process. For something that was discovered almost a hundred years ago and was not patented, insulin sure is way too expensive today in my home country (0 points for guessing where). Imagine how bad it could be if it had been patented from the start.
@millersam07
@millersam07 2 жыл бұрын
I think we need Banting to come back and beat up the for profit medical system we currently have
@Echo81Rumple83
@Echo81Rumple83 2 жыл бұрын
@@millersam07 amen
@jannegrey593
@jannegrey593 2 жыл бұрын
Insulin is also expensive in other places. In Poland my father's stock of insulin for 8 months costs around 200 dollars. Thankfully Glucometers are free with prescription for strips (I sent one to a friend in US) and strips with prescription cost only about a dollar for 50 (without prescription price is about 10 times). The reason partially is that companies use their own refined methods of mass producing insulin. By that I mean artificial insulin. Of course it should be cheaper, but that is only part of problems your country is facing. Without Universal Healthcare system - every insurance company negotiates for themselves. In Poland government speaks for 38 million people, so they can bring the prices down.
@abooper960
@abooper960 2 жыл бұрын
It’s expensive because Canada sold the patent for it to the USA
@matthewferrantino9521
@matthewferrantino9521 2 жыл бұрын
Private profiting is a two edged sword. In the hands of someone less trustworthy it would make it worse. But someone who asserted themselves as wanting to control it only because they distrusted other organizations but trying genuinely to make it cheaper for people can probably do more for people than the government. It's like the risk of a bad king vs wanting a good king to be powerful making it hard to figure out if monarchy is a better system or not. In the end really neither system is better: individual people will either use the systems in good faith, or they won't. A good person can make do with any system.
@lopali
@lopali 2 жыл бұрын
Nicolae Paulescu also made significant contributions to the discovery of insulin. He made a similar extract, and by the time Banting and Best isolated insulin in February 1922, he was already awaiting the patent confirmation for his 'pancreine'. Roif Luft, president of the International Diabetes Federation in 1971 and chairman of the Nobel Prize Committee for Physiology and Medicine, stated that "One fact remains, namely that the earlier discovery made by Paulescu was misinterpreted by Banting and Best for reasons which we cannot know anything about today … In my opinion, the [Nobel] prize should-without any doubt-have been shared between Paulescu, Banting and Best." Please at least make a note in the 'Lies' episode
@su1t0n11
@su1t0n11 2 жыл бұрын
Thank you! It's pretty sad that he dosen't really get recognition if at all.
@donaldduck9884
@donaldduck9884 2 жыл бұрын
I'm curious if Paulescu the ultra nationalistic antisemitism who administrated the insulin extract rectally instead, had same opinion about the medicine most be cheap and access for everyone have right and afford to buy it?
@matthewferrantino9521
@matthewferrantino9521 2 жыл бұрын
My take might be kind of hot here, but it sounds like Banting wouldn't have liked anyone who wanted to patent, and maybe he let that straight up prejudice him?
@mattmathematics3591
@mattmathematics3591 Жыл бұрын
@@donaldduck9884what does any of that have to do with this 🤷 ford was an absolute ahole u still learn abt him and the founding fathers owned slaves
@donaldduck9884
@donaldduck9884 Жыл бұрын
@@mattmathematics3591 Founding father? I'm totally confused what you are talking about so pls explain better what you talking about?
@thinkfact
@thinkfact 2 жыл бұрын
Anybody with the loved one who's suffering from the effects of diabetes, this sort of stuff can actually make you emotional.
@MontyBeda
@MontyBeda 2 жыл бұрын
My son was diagnosed with diabetes two weeks ago so he is alive only thanks to insulin now. So really looking forward to watching this after he will be sleeping in half an hour hopefully :-)
@kaymuldoon3575
@kaymuldoon3575 2 жыл бұрын
Sending good thoughts for your son. 🙏🏻🙏🏻🙏🏻
@Kaanfight
@Kaanfight 2 жыл бұрын
The discovery of Recombinant Insulin also was huge in making life better for people with diabetes. As stated in the video, the 14 year old had an allergic reaction to the beef insulin. Recombinant Insulin was created by using bacteria to create human insulin by biomedical engineering in the 70s. This greatly reduced the risk of an allergic reaction due to impurities and the foreign elements in boar and cadaver insulin, which were used since its first discovery. Science!
@kestrels-in-the-sky
@kestrels-in-the-sky 2 жыл бұрын
How much is his insulin costing you If your in the us
@MontyBeda
@MontyBeda 2 жыл бұрын
@@kestrels-in-the-sky Luckily we are in Czech republic so we are not paying anything. Got insulin pump for free, sensors for free, insulin for free, education about it all, glucose meter which also measures ketone levels and all the testing strips for it (just both one set of ketone strips with my own money), all the infusion sets for the insuline pump and also disinfectant and such for the changing of them. And also the emergency syringe for hypoglycemic shock was for free. So glad we live in developed country with universal healthcare as quick sum of all the stuff is around 130 000 CZK so around 6 000 USD.
@tntfreddan3138
@tntfreddan3138 2 жыл бұрын
I'm gonna ruin you moment of 69 likes. Here's a like to you and your son. Give him a hug from me. I may not have diabetes but I at least know that emotional support is very important in trying times. I've had a lot of trying times but rarely got the support I needed. I wish him well. 😁
@ModelAAA90
@ModelAAA90 2 жыл бұрын
Fame, Recognition, and Fortune. Some of many reasons why humanity may never know progress among its good and talented men and women… 😔
@bungalo50
@bungalo50 2 жыл бұрын
Wealth, fame, power. The world had it all won by one man: the Pirate King, Gold Roger!
@Rafaelrgm
@Rafaelrgm 2 жыл бұрын
Funny is that MOSTE of them generally agreed to forfeit the fortune part, from what was said in the video, the fights seemed to be mostly boiled down to fame and recognition.
@matthewferrantino9521
@matthewferrantino9521 2 жыл бұрын
I think that when people are desperate, they honestly will let go of these temptations. Everyone is naturally tempted, but most want to overcome it.
@whathell6t
@whathell6t 2 жыл бұрын
@@bungalo50 *Pirate King, Atomsk; not Gold Roger.
@TKOS96
@TKOS96 2 жыл бұрын
@@bungalo50 Actually, it's Gol D. Roger.
@crashedfighterproductions
@crashedfighterproductions 2 жыл бұрын
I owe these men my life. I was diagnosed at 8 months old, and nearly died. 20 years later, and I'm still here. I'm super excited for this series!
@peregrinemiles7936
@peregrinemiles7936 2 жыл бұрын
Humans: simultaneously the most amazing and most horrifying thing. As sir Terry Pratchett put it; “ where the falling angel meets the rising ape”
@SebastTapia
@SebastTapia 2 жыл бұрын
*Terry Pratchett voted best author ever*
@Syurtpiutha
@Syurtpiutha 2 жыл бұрын
"They resolved not to profit of this discovery". A noble goal. Too bad that others did not share this conviction. In case the price-hiking of insulin over the past decade wasn't enraging enough on its own.
@jamesboyle6134
@jamesboyle6134 2 жыл бұрын
This one really hits me where I live. I am Type 1 diabetic, and only discovered when I was brought to Accident & Emergency (what we call ER). I had been feeling rundown with a terrible thirst for a few weeks. Then the vomiting and cramps started. And then the vomit turned black... When the nurses examined me, it turned out I was suffering from diabetic ketoacidosis, which happens when a person's blood sugar is far too high for far too long. Needless to say, I was in the High Dependency Unit and then a general diabetes ward for about a week. Without insulin, I literally would not be alive today.
@matthewsteigauf470
@matthewsteigauf470 2 жыл бұрын
I'd love to see a series like this or a one off on the development of the pacemaker. I got my degree in biomedical engineering from the University of Minnesota and it's kinda just a common legend there. And, WOW, is it a good example of why having regulations are good.
@malachiphoniex8501
@malachiphoniex8501 2 жыл бұрын
I second this.
@militustoica
@militustoica 2 жыл бұрын
My 86 year old grandmother whom I am very close to had to get one. She got CoVid-19 and had no primary symptoms whatsoever. Then almost as soon as she recovered she developed major arrhythmias. She had a profoundly healthy heart for her age before then and no cardiac family history. The doctors said it was most likely the far more pernicious Post-Acute Sequillae. They were able to put it in with pin-hole laprascopy in twilight sedation, but she goes in about once every 30-60 days because of remote monitoring issues now for medication adjustments or defribullation.
@danknigel5430
@danknigel5430 2 жыл бұрын
Jarvik artificial heart would be cool too
@JackDelta
@JackDelta 2 жыл бұрын
Yeah that would be cool
@mckayleepugmire9947
@mckayleepugmire9947 2 жыл бұрын
The end of this comment makes me worry about the test subject involved in the project, but my grandma's had a pacemaker for years sooo...
@Gwallacec2
@Gwallacec2 2 жыл бұрын
Matt, James, Rob, Dan.... Thank you for posting this. Thank you for making this series. I had no idea the toll diabities takes on a person both Type 1 and Type 2 until I heard the story from my girlfriend. She has had T1D since she was five and ever since I found out about her condition I've been looking for videos that advocate for information to be shared that's factual like I know your channel strives for. The price of any disease is so high and showing the emotional toll is so critical. I cant wait for the rest of these videos to come out. I've supported you for years and you continue to surpize me constantly with the critical information you share with the KZbin community. I also am so happy to see the Medicaid link and the advocacy. Together through information we can cure the world. I would be interested to see more coverage of rare diseases on this channel. Thanks again!
@briannamcdaniel266
@briannamcdaniel266 Жыл бұрын
Is she doing better now?
@adunsavior
@adunsavior 2 жыл бұрын
We need Banting to come back as a ghost and haunt the pharmaceutical executives and shareholders day in and day out.
@_ayohee
@_ayohee Жыл бұрын
Ghost of medicine past
@penname8441
@penname8441 Жыл бұрын
+
@powersell8589
@powersell8589 2 жыл бұрын
I am disappointed to see that there is no mention of Nicolae Paulescu or any other scientist before them.
@Itagamo
@Itagamo 2 жыл бұрын
Yeah extra history.
@stuartwhite4610
@stuartwhite4610 2 жыл бұрын
Always makes me feel pride as a Canadian that someone from my country developed this treatment. And was selfless about distributing
@zakariaraqiq
@zakariaraqiq Жыл бұрын
From a type 1 diabetic, thank u Canada
@stefanbirlog4622
@stefanbirlog4622 Жыл бұрын
​@@zakariaraqiq Romania did it first
@polarpunk8861
@polarpunk8861 9 күн бұрын
My boyfriend is a type 1 diabetic and I'm eternally grateful to those men for creating insulin to save countless lives. I just wish here in the states it was cheaper
@elliotttheneko
@elliotttheneko 2 жыл бұрын
When thinking about island riches, we think of spices, sugar, exotic fruits and the like. But perhaps, the most important of all island riches are the ones in us all. (Islets of Langerhans)
@Praisethesunson
@Praisethesunson 2 жыл бұрын
Let's plunder those islands for corporate profit.
@espio87
@espio87 2 жыл бұрын
I claim those islets in the name of the Spanish Crown and our Beloved King Ferdinand II of Aragon and our Queen Isabella I of Castile! **plants flag into my own pancreas**
@andrewenderfrost8161
@andrewenderfrost8161 2 жыл бұрын
@@espio87 you can have mine :/ they're not functional anyway
@IcecreamMcGuy
@IcecreamMcGuy 2 жыл бұрын
Well time to colonize my body britain and France eat your HEART out
@theoutlook55
@theoutlook55 2 жыл бұрын
Nice man.
@royaltytries
@royaltytries 2 жыл бұрын
When I was a toddler , I was rushed to the hospital and later diagnosed with type 1 diabetes. Every day since, I use insulin to keep myself alive. And I’m so incredibly grateful, you guys are telling this story! 100 years ago, I would have been Pronounced dead as soon as I got diagnosed. Now? I can live my life, I just need a small injection once in a while and a machine that has insulin inside it to act as my pancreas. your telling the story to the people who have never heard it, who need to hear it! And to that? I am so incredibly grateful. Love you guys, You keep up the amazing videos and your great ♥️
@ZechsMerquise195
@ZechsMerquise195 2 жыл бұрын
It's strange. My father had type 1 diabetes his entire life and I have a strong genetic disposition to developing diabetes. But I never thought to look up the history of Insulin. Thanks Extra Credits for once again broadening our minds and teaching us new stories.
@ttvnulatics3870
@ttvnulatics3870 2 жыл бұрын
I have had diabetes for almost 7 years now, very glad medicine has progressed enough to keep me alive 👍🏻
@thecanadian8206
@thecanadian8206 2 жыл бұрын
thx for your username and god bless you
@AegixDrakan
@AegixDrakan 2 жыл бұрын
Best of luck managing your condition!
@ArthurBCamara
@ArthurBCamara 2 жыл бұрын
As a Type 1 diabetes myself, I'm literally with teary eyes to see something so meaningful for me in one of my favorite channels. Thank you. Thank you. Thank you.
@andrewweitzman4006
@andrewweitzman4006 2 жыл бұрын
What I enjoyed was both the heartwarming medical miracle story mixed with the acknowledgement of the deeply flawed people involved in it. *lays a wreath for the doggos*
@Sir_Uncle_Ned
@Sir_Uncle_Ned 2 жыл бұрын
As a Type 1 Diabetic, I am very thankful that this discovery was made with an express desire against profit. I have lived with this condition for the better part of a decade now and in this age of modern medicine, it's just an inconvenience rather than a death sentence. I look forward to seeing more of this series.
@bigj1905
@bigj1905 2 жыл бұрын
You should create a “Extra Medicine” channel. I really like learning about the discovery of vaccines, the history of diseases, and other general medical knowledge.
@georgechapman9688
@georgechapman9688 2 жыл бұрын
I'd watch that
@Overhazard
@Overhazard 2 жыл бұрын
I'd like to see it expanded into an "Extra Science" channel. Interesting things occur in the other branches of science too, and its history thereof. Stuff like the life of Antoine Lavoisier (discovered oxygen, invented medical cross-ventilation, revolutionized tobacco farming, Mrs. Lavoisier translating scientific papers from English to French for him and his papers from French into English for publication, rewarded by being sent to the guillotine during the French Revolution), Erastothenes's technique in ancient Greece for measuring the circumference of the Earth to an error of less than 3% (they knew the world was spherical, and Aristotle could prove it in five different ways), the Stanford Prison Experiment (which had to be called off after less than halfway through due to the madness the people undergoing it were experiencing), and, while this is still ongoing, a rundown of the atomic elements discovered by Yuri Oganessian (who discovered or helped discover twelve elements--bohrium, meitnerium, hassium, darmstadtium, roentgenium, copernicium, nihonium, flerovium, moscovium, livermorium, tennessine, and oganesson, the last of which was named in his honor by his team--the most of any one person, and is still alive and still looking for more). Speaking of chemical elements, polonium has quite the rich history, used for both good and evil. Marie Curie named it to bring awareness of her home country of Poland, and it is extremely radioactive, so much that it was used by Russian spies to discreetly poison KGB defector Alexander Litvinenko...and was radioactive enough that the taxi he rode had to be decommissioned for being too radioactive to use simply because he sat in it for half an hour after ingesting a grain of polonium.
@history-jovian
@history-jovian 10 ай бұрын
We already have too many extras. Extra SCIFI, Extra Credits and Extra history.
@battledroid7628
@battledroid7628 3 ай бұрын
@@history-jovianextra mythology
@papplebeast5039
@papplebeast5039 2 жыл бұрын
Type-1 and Type-2 diabetes aren't different because of the age of the person they inflict. Type-1 diabetes is when your body loses the ability to produce insulin. Type 2 diabetes is when your body becomes resistant to insulin. Type-2 diabetics still produce insulin.
@goranvujovic27
@goranvujovic27 2 жыл бұрын
As a diabetic, this brings me great joy that you are dedicating a mini series to this. The history is very interesting and your guys videos are ones that I have been watching for years. So thank you.
@andromeda331
@andromeda331 2 жыл бұрын
Wow, how amazing. I can't imagine what it felt like to be a diabetic who thought you had a death sentence to find out that there was something that could save your life. Save countless lives. That's wonderful.
@ChiaraVet
@ChiaraVet 2 жыл бұрын
I deeply appreciate that you haven´t hidden the fact that this life changing achievement of modern science and medicine was made thanks to animal research (without the repeated experiments it would have took way longer to save those children and many others after them... and we have seen that time is never on the side of science). Even today that is a fundamental part of basic research, and the laws about animal welfare in place and the advanced technology allow us to avoid such cruel experiments. Many newspapers avoid reporting the part of a research that was done on animals and this is a type of misinformation we need to avoid. I understand that it is a difficult topic but we also need to say things how they are, we need to face reality.
@hopeless6905
@hopeless6905 2 жыл бұрын
I love that you’re doing this. My girlfriend is a type 1 diabetic and it’s awesome to learn the history of what keeps her alive
@feldmarschallvonbraunschwe4463
@feldmarschallvonbraunschwe4463 2 жыл бұрын
Ah! My university, really cool to see some Canadian history. We don't get much coverage and this is a perfect topic!
@kiranederlof5014
@kiranederlof5014 2 жыл бұрын
My brother is diabetic, this is a series i look forward to watching.
@professorcube5104
@professorcube5104 2 жыл бұрын
My grandfather is also diabetic
@danielgraumann87
@danielgraumann87 2 жыл бұрын
Being a type 1 diabetic, there discovery really saved my life and allowed me to grow to an age to have children and make memories with my family. However, there is still cost to it that is causing me great harm. From the high cost of the drug that keeps me alive day to day that has driven me into thousand of dollars in debt to the constant testing of my blood to keep track of my blood sugar levels and the hardness of trying to find nutrition information that I need to take the right amount of insulin. With these things still prevalent, it feels like there is no cure yet to the type 1 diabetes at least not until an artificial pancreas is made which I hope is soon. 🙏🙏
@rosiehawtrey
@rosiehawtrey 2 жыл бұрын
You can buy handheld testers for a few tens of $. You need the test strips and those little snap pin things (don't know the technical term) but those will give you enough information about where your blood sugar is. Places like aliexpress or ebay or even Amazon if you want to buy Bezos more yachts. I'm guessing you are in the US - and Dr's will connive with the companies to reel you in for unnecessary lab tests that can be done on this sort of unit at home. Ex partner had it amongst other people. Test in the morning first thing and at night - if yours tends to go on the low side keep chocolate or something similar available at all times.
@sethhomer1681
@sethhomer1681 2 жыл бұрын
I myself have type 1 diabetes, so glad that we have insulin today, but I really wish that insulin was affordable here in the US
@ZeMalta
@ZeMalta 2 жыл бұрын
Man, I know life is hard, but damn, to hear them be so adamant in take no profit from this is very heartwarming.
@willtanker7684
@willtanker7684 2 жыл бұрын
brilliant, a series on exactly how my life was saved! not living under the deadly healthcare system of the U.S that withholds live saving treatments behind a paywall only surmountable with one's life savings and getting insulin nearly for free (as these great men intended) I am very interested in how they not only came up with the treatment, but how doctors in the 1920s managed to stay in agreement to not profit off of the literal lifeline of thousands of people.
@Vertigo6000
@Vertigo6000 8 ай бұрын
As someone who was just recently diagnosed with diabetes. This series has taken on a whole new perspective for me. Im so greatful that this discovery was made, and right here in my own country too.
@NoGoodHandlesLeft
@NoGoodHandlesLeft 2 жыл бұрын
Fun Fact: Sir Frederick Banting did get his due and was one of the last Canadians given a knighthood.
@royalewithcheese7
@royalewithcheese7 2 жыл бұрын
American pharmaceutical companies: "We can milk this!"
@intermediategamer6871
@intermediategamer6871 2 жыл бұрын
My brother actually has diabetes type 1, so this was a very informational video and I loved it!
@24dasr
@24dasr 2 жыл бұрын
This was one of the most important scientific discoveries in history and they decided to make this life saving thing cost extremely high amounts of money that most people can't afford to spend
@johneverett484
@johneverett484 2 жыл бұрын
I was scrolling through my recommend when I saw this video, me and my brother have had type 1 diabetes for a while and I’ve really wanted to learn about the discovery of the thing that is keeping me alive, thank you guys for doing this!
@billybossier2888
@billybossier2888 2 жыл бұрын
We should never forget that then the pharma companies then took over and started charging hundreds of dollars for Insulin.
@AegixDrakan
@AegixDrakan 2 жыл бұрын
Yeah, it's insane and downright evil how much money US pharma companies charge for insulin. Especially if you look up in Canada and see that you can get a bottle up here for under 20 bucks. It does NOT need to be as expensive as it is down south. :(
@arieldahl
@arieldahl 2 жыл бұрын
albeit, a problem that roots in the American medical system... I hope the US will wake up and rework the system but unfortunately, I won't hold my breath.
@andrewenderfrost8161
@andrewenderfrost8161 2 жыл бұрын
this video dropped right as I got my first continuous glucose monitor prescribed. Remembering my 2 weeks of this made it almost too hard to finish the video, those poor children :/ Thanks Extra Credits team for being so wonderful.
@pentagonofpeople
@pentagonofpeople 2 жыл бұрын
It's great watching this and how intent they were on not profiting from it and then seeing that a month of insulin costs hundreds of dollars
@purpledevilr7463
@purpledevilr7463 2 жыл бұрын
Hopefully the end of this mentions the current patent of insulin and how millions die from not affording it. It’s sold at over a 50X mark up.
@nathanx2000.
@nathanx2000. 2 жыл бұрын
I owe my life to these researchers
@evanulven8249
@evanulven8249 2 жыл бұрын
Scientists and Doctors: "Insulin is such a required substance that we've made it literally cheaper than dirt so everyone that requires it to survive can get it when they need it!" Unbridled murrikan ancap phama corps: "Hhehe literally captive customers have to pay ransom or die." Well-trained apologists: "Ah-ah-ah! Saying that's wrong mean you're a communist!"
@mw5502
@mw5502 2 жыл бұрын
It's not literally cheaper than dirt to produce, but it is fairly cheap to produce. There's a massive markup.
@luska5522
@luska5522 2 жыл бұрын
i get it for free in Brazil. Free Healthcare is great
@SafavidAfsharid3197
@SafavidAfsharid3197 2 жыл бұрын
I doubt evryone who don't agree with American pharma looting it's people are communist like the capitalist pharma companies of india and china would like very much of there cheaper product would get access to American markets and break the monopolies.
@Phhase
@Phhase 2 жыл бұрын
Damn corpos ruin everything. Curses upon them all.
@KasumiRINA
@KasumiRINA 2 жыл бұрын
@@SafavidAfsharid3197 That's the point. People who call those who want America to get better healthcare system "communists" are wrong.
@MustardLadySaveMe
@MustardLadySaveMe 2 жыл бұрын
How upsetting to learn that insulin was developed with the intention of being free to anyone who needs it. Pharmaceutical companies charge 25x the cost to produce insulin, and our government just sits back and says nothing while taking "donations" from those same companies.
@alexanderrowley9870
@alexanderrowley9870 2 жыл бұрын
These medical histories have ended up being my favourite stories EH does. From John Snow to JDR's polio drive, they've all been really interesting :)
@tomholmes5055
@tomholmes5055 2 жыл бұрын
I've been a Type 1 for 12+ years now. Amazing to see how far we've come in 100 years.
@a_pirate1434
@a_pirate1434 2 жыл бұрын
Thank you for doing a series on this- some aspects of history are easily drowned out by talk of kings and generals, yet have had a stunning impact on people’s lives- like this. Had I been diagnosed with T1 Diabetes a century earlier than I did, I would’ve certainly been dead by age 6, but with modern medicine life expectancy for T1 diabetics is approaching parity with non-diabetics. Truly revolutionary.
@limratanak1716
@limratanak1716 2 жыл бұрын
100 years ago there is a drama that saves millions of lives.
@reine_dragon
@reine_dragon 2 жыл бұрын
It's so interesting learning about the people two schools near me are named after. Dr Charles Best secondary and Banting elementary
@Vigirebs
@Vigirebs 2 жыл бұрын
I’m not usually one for tears but thank you guys. I really hope you can bring some more attention to this with your special touch. A 3 month supply of just one type of insulin can cost 1700 without insurance here in the US Type 1 since 2018
@juhaniheinonen6132
@juhaniheinonen6132 2 жыл бұрын
As a type-1 diabetic it is very cool that you bring up the history of this lifesaving medicine.
@FlaviusBelisarius-ck6uv
@FlaviusBelisarius-ck6uv 2 жыл бұрын
As a med student, I’ve been waiting for this!
@dbrokensoul
@dbrokensoul 2 жыл бұрын
Wow. This episode is amazing. That moment when the parent cried is wonderfully written and delivered. I love this series already
@xvang9346
@xvang9346 2 жыл бұрын
A whole series of medical discoveries would be interesting. Some interesting ones would be the first successful surgery of any organ i.e. kidney and heart. Or the discovery of certain medications that revolutionized the way we treat patients today. Excellent video.
@Mordeczka1234
@Mordeczka1234 2 жыл бұрын
I love your medicine related videos! Please make more of them!
@bobpiss3400
@bobpiss3400 2 жыл бұрын
Scientists: agree not to profit off the discovery pharmaceutical companies: *yoink*
@medeastar
@medeastar 2 жыл бұрын
I'm now not only looking forward to part two, but to the future medical breakthrough episodes Really helps young people nowadays to watch something entertaining, but also educational So from the bottom of my heart, thank you Extra Credits for making History fun for me and my family
@davidt1d
@davidt1d 2 жыл бұрын
This series is going to be awesome and it’s so great you said how type 1 and type 2 are different
@zodayn4767
@zodayn4767 2 жыл бұрын
Sounds like this could make a good TV-show with all that drama.
@drmajalis1583
@drmajalis1583 2 жыл бұрын
Finally a Canadian story! And one of the best!
@ryanelliott71698
@ryanelliott71698 2 жыл бұрын
I’m very glad he’s covering this. It really was a game changer.
@loke6664
@loke6664 2 жыл бұрын
It was certainly one of the most important medical discoveries ever made together with vaccine for polio and smallpox. It is sad that we haven't been able to cure the condition by now though. A friend of mine died this spring 49 years old due to complications of his diabetes and I feel like it is something we should have the competence to cure for good by now. Still, insulin did give my friend 20 years of longer life and many even more. It is a shame the inventors fought so much about one of the most important discoveries in history.
@kevindidi6343
@kevindidi6343 2 жыл бұрын
Super proud to see my university (and our most proud contribution) featured in an Extra History! Thanks for the informative video!
@cr0ptix888
@cr0ptix888 2 жыл бұрын
Thanks for making this to educate people about diabetes and im honestly tired of explaining it to new people
@cr0ptix888
@cr0ptix888 2 жыл бұрын
I have type 1
@pixelnpc8480
@pixelnpc8480 2 жыл бұрын
This landed right in my feed not but three minutes ago. Good timing there guys!
@keegandecker4080
@keegandecker4080 2 жыл бұрын
Alright guys listen. I’ve been here since the first Punic war but this was the first time since Flanders fields that an episode of EC has brought me to tears. Those poor children.
@colinmunro3158
@colinmunro3158 2 жыл бұрын
It has been said that insulin was the last medical advancement not motivated by profit. Additionally, the development of insulin is a point of great pride among Canadians.
@JohnnyLodge2
@JohnnyLodge2 2 жыл бұрын
Aww yeah. Multi part science/medicine episodes are the best
@Honest_Abe1
@Honest_Abe1 2 жыл бұрын
[Gets Spanish flu flashbacks]
@alex_zetsu
@alex_zetsu 2 жыл бұрын
So far Macleod might seem like overly skeptic, but in these fields it doesn't hurt to be really sure.
@timothycarney9652
@timothycarney9652 2 жыл бұрын
It will be interesting to get to the part of the story where we find out what happened between- no patenting any of this and selling the formula for a dollar, to the current insulin prices.
@cutterlmao
@cutterlmao 2 жыл бұрын
To think that without four people constantly fighting with each other to achieve the same goal, I wouldn’t be here without them. That’s truly amazing, and I’m glad they could do this
@thepoglin8479
@thepoglin8479 2 жыл бұрын
man its a good day when extra credits posts a new series
@tubanbodyslammer9125
@tubanbodyslammer9125 2 жыл бұрын
This made me tear up. Great story
@tamelo
@tamelo 2 жыл бұрын
I imagine there were no Insulin denier that refused treat their children with that "experimental" drug.
@rosiehawtrey
@rosiehawtrey 2 жыл бұрын
You'd be surprised.
@KuleoRoblox
@KuleoRoblox Жыл бұрын
I love how almost everyone in that research team hated/disliked eachother yet they United for sake of humanity
@ThisisallMax
@ThisisallMax 2 жыл бұрын
These are some of my favourite EH series!
@romaboo6218
@romaboo6218 2 жыл бұрын
Extra history is my favourite history channel been watching it for like 4 or 5 years now
@lordphinix3
@lordphinix3 2 жыл бұрын
As someone who attended Banting High School in the very town where Banting was from I am most interested in this.
@TheNashNetwork
@TheNashNetwork 2 жыл бұрын
Wow this is a great start to the series. In BC we have high schools named after Banting and Best, and I didn't know they were the doctors behind the discovery of Insulin!
@shawnheatherly
@shawnheatherly 2 жыл бұрын
I am loving this drama over such a good discovery.
@NYCfrankie
@NYCfrankie 2 жыл бұрын
So happy you guys are doing a story on this my whole family on my dads side struggles with type 2 diabetes and high glucose I've personally been borderline diabetic for 5 or 6 years and have to watch my sugar intake my dad b4 he died though i remember his doctor telling him and me the story about the insanity of insulins creation on a regular visit i took him 2 but nowhere near in depth like this so i find it fascinating can't wait for part 2
@babakkhaleghiborna7027
@babakkhaleghiborna7027 Жыл бұрын
As a diabetic who was diagnosed as I was 6, I owe my life health through a pretty easy way to control my situation to these people ❤❤❤
@alexkarasz6186
@alexkarasz6186 2 жыл бұрын
This is one of my favorite stories ever
@thechildinyourbasementlol2986
@thechildinyourbasementlol2986 14 күн бұрын
Thanks, an actual engaging video I can use for history class
@TheC0Opper
@TheC0Opper 2 жыл бұрын
I love seeing more being informed about this, as I got Diabetes type 1 at age four. In recent years awareness has grown a lot more but when I was younger I've often gotten either bullied or confused by others that I didn't exercise or diet good enough etc. etc., often stemming from a confusion between type 1 and type 2. The big difference between the two is that type 2 is more becoming resistant to insulin, not having as big of an effect while type 1 is a lack of production of insulin in the body, having to inject it manually. Having more people be aware of this disease others often dismissed as just a joke on obesity, makes me happy that others won't have to endure what I did mentally, while still having to struggle with a chronic disease on top of that.
@IcecreamMcGuy
@IcecreamMcGuy 2 жыл бұрын
Dude I love this video. As always this was such High quality and informative
@crimsonghost235
@crimsonghost235 2 жыл бұрын
Banting and best are highly honoured in Canada. An elementary school shared their name, and theres reference to their discoveries on our 100$ bill
@Revy8
@Revy8 2 жыл бұрын
Dr. Fredrick Banting was born in Alliston, Ontario, Canada. My highschool is named after him n his childhood home is a protected building in the town.
@Tyrandir
@Tyrandir 2 жыл бұрын
I've been hoping you guys would do a series on insulin, this makes me so happy! It'll be nice to have an easy and fun way to explain how that loophole mentioned here would come back 100 years later to such disastrous effect. I hope you get the chance to talk a bit about the projects like Open Insulin :D
Khóa ly biệt
01:00
Đào Nguyễn Ánh - Hữu Hưng
Рет қаралды 22 МЛН
1 or 2?🐄
00:12
Kan Andrey
Рет қаралды 36 МЛН
He sees meat everywhere 😄🥩
00:11
AngLova
Рет қаралды 10 МЛН
БОЛЬШОЙ ПЕТУШОК #shorts
00:21
Паша Осадчий
Рет қаралды 8 МЛН
Why Insulin Is So Expensive | So Expensive
8:19
Business Insider
Рет қаралды 1,2 МЛН
The Deadliest Infectious Disease of All Time | Crash Course Lecture
49:57
Pellagra - A Medical Mystery - Extra History
11:03
Extra History
Рет қаралды 1,5 МЛН
Japanese Militarism - Drawing the Knife - Extra History - Part 1
10:32
Ancient Rome’s most notorious doctor - Ramon Glazov
5:11
TED-Ed
Рет қаралды 3 МЛН
How There Could Finally Be A Cure For Diabetes
20:02
CNBC
Рет қаралды 1,7 МЛН
Awful Things Doctors ACTUALLY Said To Patients
14:53
Doctor Mike
Рет қаралды 3,3 МЛН
Khóa ly biệt
01:00
Đào Nguyễn Ánh - Hữu Hưng
Рет қаралды 22 МЛН