Flow of cerebrospinal fluid (CSF)

[@michaelpolei4797]

Thank you much Dr. Doherty! This is a great use of educational medium and was very descriptive and easy to follow.

[@razan5376]

SO TRUE!! I really liked it. Thank you for it, Dr.

[@ramsajiwan4553]

Are u in medicine .

[@josebriceno2785]

I was not expecting find something this detailed and beautiful 🤩

[@katdekarachisimba1056]

What a wonderful and an informative video! Thank you!

[@terpgirlzy]

beautiful 3D demonstration of the ventricles. Thank you.

[@3ammak]

@1:43 - CSF flows in the subarachnoid space in the spinal cord and not subdural.

[@bristolneuroscientists1094]

oohh - do I say sub-dural? Thanks for that - will put a correction in.

[@aneetakapoor4486]

3ammak

[@andywang4310]

Thanks was looking in the comments specifically for that part.

[@dannichols6261]

@@bristolneuroscientists1094 Yes, but isn't subarachnoid *still* wrong? Doesn't CSF flow down the *central canal* , down to an opening at the end/bottom, where it then flows *up* through the subarachnoid space?

[@param4553]

@@dannichols6261 it flows both way in the spinal cord via the central canal as well as around it in the sub arachnoid space.

[@Muuip]

Great concise visual presentation! Much appreciated! 👍

[@Jasmine-ll8qu]

Wonderfully explained and animated!! Thank you so much

[@TxLoneStar817]

I’m going threw EMT to Paramedic... thanks for all your help!

[@mb7050]

finally spinal fluid movement included . thank you

[@dianederita2758]

Amazing video, info and visuals. Very cool.

[@ikidd06]

Fantastic animation! Best I've seen

[@prashantkhatal217]

After long time I cleared my concept

[@dannichols6261]

Thank you, this is well done! Besides the useful content & animation, you took the time & effort to put in *actual* closed-captions (rather than just often inaccurate 'computer-generated' ones), and you thoughtfully put in a 'table-of-contents' to jump to specific places in your video! And by using the term 'cistern' (which I think are enlargements of the sub-arachnoiod space?), it may help me to figure out what a speaker in another video which did *not* have actual closed-captions may have been saying. Kudos!

[@nageshg2229]

Add

[@dannichols6261]

@@nageshg2229 Hi Nagesh! What does your comment 'Add' mean?

[@shagashreyan]

@@nageshg2229 aà

[@jman7306]

The animation style is strange, but I feel like its uniqueness will help me remember, Thanks!

[@bristolneuroscientists1094]

haha - that's Muvizu for you :)

[@livingforfree2]

Could you explain a little more regarding the direction it takes going up and down the spinal chord to the brain? Does it start on the right side exciting down the left side?

[@dr.thomasfastiggi232]

It flows inferiorly on the dorsal aspect of the cord . After dumping inferiorly in the lumbar cistern sacral nutation powers its flow superiorly on the ventral aspect of the cord.

[@graemegeorgeharrison2468]

Is there anyway to check whether my CSF is circulating correctly, I am suffering with chronic inflammation and pain in my eyes and brain. I Really need help

[@LexusFox]

This form of animation is so bizarre, it makes me feel uneasy.

[@bristolneuroscientists1094]

That's an interesting response - why uneasy?

[@LexusFox]

I'm not sure. The lecture is interesting and I like the subject, but for some reason those characters look so bizarre that they make me feel uneasy.

[@Caliscris]

I'd have to agree actually It kind of reminds me of the lawnmower man

[@lgc41004]

Kinda has a salad fingers vibe to me

[@LexusFox]

​@Mr R to the B Thank you! I totally forgot about this comment haha Now starting my 2nd year of med school and it's funny to me that I was watching these sorts of videos way beforehand.

[@TheEDNC]

CSF flow dynamics are interrupted and even halted when Adhesive Arachnoiditis is present. Studies are necessary to analyze the effects of restoring CSF in these patients.

[@BeenaKaKitchen]

Increase flow of csf can effect bloood circulation to brain? Reply plz

[@bristolneuroscientists1094]

unlikely - there's more than enough capacity to cope with an increase in flow ... increase in VOLUME however causes hydrocephalus

[@fatherpetey2866]

Came for the education- stayed for the sick animation.

[@bristolneuroscientists1094]

Aha - my plan is recognised! Glad you liked it

[@Serenity7250]

So, any idea on how to get prompt medical help on the NHS after being diagnosed with a CSF leak? I have a hole in my dura and am fighting every step of the way to be heard and hopefully fixed. Where are the specialists? How do I get in touch with the right people? When leaking csf...you dont really have time for waiting lists.

[@Serenity7250]

@THE matrix I kept going to Accident and Emergency until they gave me an MRI which showed Intracranial Hypotension, evidence of a leak. They then gave me an epidural blood patch which helped alot. I'm still not fixed though and only have about 3 hours upright time a day. My neurologist has referred me to a csf leak specialist in London who looked at my scans and is apparently ordering more scans to be done locally. I'm still just waiting.

[@Serenity7250]

@THE matrix After 3 hours I start getting a burning head pain around the back of my head. It gets worse and worse until I lie down. It goes away when lying down. It's called 'Spontaneous intracranial hypotension' because it's spontaneous. It happens out of nowhere.

[@Serenity7250]

@THE matrix A spinal csf leak can cause your sinuses to run but it only effects 5 in 100,000 people. You might just have non-allergic rhinitis or a sinus infection that's causing the headache with runny nose and need a spray from your doctor. Csf leaks are very rare so it would be very unlikely that you have one. Make an appointment with your Dr so they can start investigations.

[@shadabkarim216]

Awesome exp❤❤

[@Heyitsmepotato22]

Wowww! Amazing animation

[@evelisisdavis7242]

Thank you

[@martinmatko6401]

Apparently What is the role of CCSVI Venous Hypertension and proper/improved Cerebrospinal Blood flow Impacting circulation and homeostasis balance? #CCSVI #BloodFlowMatters #spasticity #perfusion Horizontal sleeping causes Reflux of De-Oxygenized blood towards the stenosed Hypoxic brain

[@martinmatko6401]

Who Knew?? #BloodFlowMatters @ms_matko Supplying Oxygen and Nutrients to every Cell along with clearing toxic brain waste, what is the role of CCSVI Venous Hypertension and proper/improved Cerebrospinal flow, impacting neurological symptoms regulating mood and cognitive Senescene Psych issues? #CCSVI #BloodFlowMatters With age, blood flow to the brain decreases b/c blood vessels produce less nitric oxide, a gas that expands blood vessel walls. Such disruptions contribute to changes in cognitive function that occur with age. #Exercise increases nitric oxide & boosts blood flow to the brain. #Urgent #BloodFlowMatters Horizontal sleeping causes Reflux of De-Oxygenized blood towards the stenosed Hypoxic brain, which after years results in MS Sleeping is a Silent threat to mankind! Keep in mind! Arteries are nothing without a Heart, and a Heart is nothing without Veins! Treatment improving Arterial Circulation is permitted and common, all treatments that improves Circulation in Veins are not widely available. #CCSVI So happens CCSVI is a treatable congenital SCIENCE CONFIRMED recognized Medical condition causative factor SO called Multiple Sclerosis & plays part/role 43 other SO called Neurological afflictions according to studies certanly Including along with other mysterious brain diseases with comparable SymptoMS!? Help facilitate Neurovascular Disease Research Best chance for longevity quality of life depends on availability Neurovascular Disease Research Collaboration. '“When we age, one of the common things that happens within our brain is that the blood vessels do become compromised in part because of chronic conditions,” it issaid. “And when that occurs in normal aging, what happens within the brain is … silent strokes.”' As much CCSVI has been Scientifically established to have a role/part in 43 so Neurological afflictions including Dementia and so called MS 'There is evidence to suggest COVID-19 impacts the same blood vessels that feed the brain. If the virus is damaging those vessels, which could speed up aging, this, in turn, means some survivors might be at risk of getting early-onset dementia.' Time for Learning Science #BloodFlowMatters Apparantly nothing else matters critical Healthcare So happens CCSVI a TREATABLE Congenital Science Confirmed Recognized Med Condition STUDIES show causative factor so called Multiple Sclerosis & role/part 43 other SO called Neurological Afflictions Incl. Migraines, Asperger ALS Autism Dementia/Alzheimer's Aphasia Optic Neurtis Tinnitus Transverse Myelitis Ect! facilitate collaboration defining the path forward establishing the understanding and treatment of Neurovascular disease organizing unified clarity in Science knowledge and progress! Critical Healthcare Research addressing Neurovascular/Cardiovascular Disease including Heart & Brain function Amygdala Dopamine/Serotonin related Mental Health Depression Vascular Disease issues! #anxiety #VascularDepressionConsensus FB Group: MultipleStenosisSociety t.co/7JNmFD7W4l Apparently What is the role of CCSVI Venous Hypertension and proper/improved Cerebrospinal Blood flow Impacting circulation and homeostasis balance? #CCSVI #BloodFlowMatters #spasticity #perfusion Horizontal sleeping causes Reflux of De-Oxygenized blood towards the stenosed Hypoxic brain CCSVI is Science Confirmed Recognized Medical Condition STUDIES show causative factor MS Varicose Veins Fatigue Atrophy Inflammatiion Thyroid issues Covid-19 Heart function matters Cramps Mental Health problems Bowel & Bladder affairs insomnia Senescene Psych unusual behavior!

[@Muuip]

Question: how does the spinal fluid flow? What makes it move around? Thank you!

[@asyrafasari1425]

Yeah me too wondering what creates the ‘pushing’ mechanics that makes it move around.

[@yleekeely]

my guess is cohesion. kind of like water+minerals through a plant stem. I came to the comment section to ask the same question. as more csf gets pumped in, more leaves and gets pushed upwards back to the top (again, my guess)

[@bertg74]

How does it flow up? When and how is electromagnetism produced?

[@Hannahi757]

Thank you! God bless

[@TheHyperactiveMelon]

I feel the drops going down my spine

[@vegvisirnewera]

I've got same problem, yesterday i learnt it, after a while I'll be gone for good, hopefully it's not painful..

[@ghifarakbar8492]

what problem ?

[@graemegeorgeharrison2468]

Are you ok? What’s happening with your condition?

[@MrAmericanaSam]

So what causes the flow? Pressure from the choroid plexi? Is there cilia or micro villi involved? Are there peristaltic contractions?

[@bristolneuroscientists1094]

the choroid plexus actively transports ions such as sodium and potassium into the ventricles - water will follow due to osmosis. Some of the fluid is absorbed by the brain while the veins and sinuses are quite porous, allowing fluid to drain into them. This creates the flow.

[@MrAmericanaSam]

@@bristolneuroscientists1094 Thank you for the response!

[@zakyalkuach6563]

I liked the video very much, it’s just I need more information on the different regions the spinal fluid flows through I’ am new to neuroscience and would like more information please

[@locuevangelismministry6227]

Wow, it's wonderful

[@sacredcoldplasma6276]

I was hoping to see an animation of the flow of the fluid

[@hellohelloitsmehi]

Hi there Bristol Neuroscientists, at 2:12 you mentioned the ventral cisterns. May I please clarify what you mean by the ventral cisterns, and which cisterns you mean specifically?

[@ryanoconnor7957]

I know this is 3 years late but from what I can tell it's the interpenduncular cistern and the pontine cistern

[@ArpinderKaur-b7w]

amazing

[@dr.denniskeenan6584]

Really good Thank you. What actually pumps the CSF around?

[@193_samridhikumar8]

Very very cool

[@akshayall9049]

Thank you so much

[@rambo-rb]

but what is the 'pump' that pushes the fluid? Similar to heart to pump blood ... what pumps the cerebrospinal fluid?

[@bristolneuroscientists1094]

Flow of CSF is determined by hydrostatic pressure from fluid entering the ventricles from the blood supply and leaving by draining into sinuses at the arachnoid villi. CSF is produced continuously from the choroid plexus, which pumps solutes across ependymal cell membranes and so water from the blood follows. That increases hydrostatic pressure, which forces the water out to the sinuses and so to the veins. The veins themselves are also quite porous so fluid drains into them directly as well. So, fluid flows from the arterial supply to the venous supply, just like in the blood stream

[@yleekeely]

what force pulls the csf up the spinal cord when it goes back toward the brain? is it cohesion like water in a plant stem?

[@lelabb4110]

Beautiful..Med School Anatomy. Thanks!

[@mustafaandsalaarvlogs2156]

great vidoe!!! one question does csf flow in the subdural or subarachnoid space in the spinal cord? the video say subdural?? also there was no mention of the flow from 4th ventricle through obex into the central canal.

[@alicek.4258]

My son has sinus and vision problems. He has improved in most areas of vision except his visual fields. Would CranialSacral therapy help?

[@justrandomthings709]

Would the cerebrospinal fluid will be soon absorbed by the body as choroid plexus produces it everyday? And where it is absorbed by the body specifically?

[@ryanoconnor7957]

but where does it flow from the pontine cistern?

[@claudiaalcarazsoler1759]

Amazing animation video!

[@nikhiltoshniwal441]

Would be help if u explain foramen of monro and lusckha.

[@fulladoll120]

Amazing✨

[@hollycumming]

Hahaa I enjoyed the animation of lecture hall in opening seconds!!

[@inderjeetkaur2779]

Wonderful work. Keep it up. I subscribed :)

[@James-Prinsep]

Decrease CSF after VP Shunt install than what to do? How we increase CSF fluid

[@simondavis1270]

Hi Great video, but is it cerebellomedullary cistern rather than cerebromedullary?

[@ytzpro]

What is the song in the beginning?

[@nanallen1]

Ah - but how does the spinal fluid get from the sacral bulb back to the brain against gravity ? The craniosacral pump and micromovements of the cranial bones - powered by breathing. Inhale - occiput moves outward, sacrum moves inward toward belly button. Exhale - the opposite happens. Read the exquisite, detailed volume : Chiropractic : The Anatomy and Physiology of SacroOccipital Technique by Jonathan Howat.

[@ربى-ض2ز]

Thank you🌿

[@netto880]

so CSF is also called Christ oil? Pls reply me

[@dorianzuniga9328]

Yes it is

[@joyalgeorge5075]

Kollam🔥🔥

[@SachinRajpoot03]

Sir how do you made this animation? it was good Enough, i wannna make one video like this, can you suggest me the platform for making this animation?

[@zenovier7689]

Interesting animation but the information you provided was incomplete.

[@bristolneuroscientists1094]

how incomplete? what else should be included?

[@trevorbates8972]

If I were to build a human body I would start with the abdomen then stretch outward as the success of my structure got stronger and stronger. The computer which controlled everything would be amongst the last attributes made necessary by all the add-ons like arms, legs, lungs, and heart, which became necessary as the thing got bigger and better. One vital part of the abdomen would prove very useful in all extended parts...a fluid...that can reach everywhere...can flush out all stale fluids and can refresh itself as we went. A fluid that could pass up the spine and act as the raw material behind CSF. We will call it lymph for now...but it requires strong Biblical guidance.

[@daveezy1]

Does anyone know what happens if there’s an absence of to and fro csf flow?

[@izzahfarhana7434]

Hi I know it's late. But with the absence of this flow there could be severe consequences such as hydrocephalus which is a condition when the CSF accumulates in the brain and leads to enlargement of the head.

[@graemegeorgeharrison2468]

@@izzahfarhana7434hi do you know where I can get checked for CSF flow? I am suffering from chronic burning and inflammation in my eyes and brain it’s really debilitating causing complete depression and memory loss I am in serious trouble. GP’s won’t help me only offer anti depression meds and counselling

[@izzahfarhana7434]

@@graemegeorgeharrison2468 There are a few tests that we can run for that. But that can only be done at the hospital and under supervision by professionals. Have you considered going to the emergency for your symptoms? A thorough clinical examination must be done to rule out many possible diseases that could affect you. But you must trust the process and get proper professional help that are leaning towards medical help instead of psychiatric help.

[@azharrather1766]

Thanku

[@Andrew-kh7rz]

A little bit higher the tone voice? It doesn t sound really loud...

[@Heligoland360]

Turn up the volume on your device.

[@MartinezCogollosDavid]

Oh... Cool

[@solar3clipse56]

Question I feel like I have a fluid between my nose and right eye and sometimes when I blink it feels like fluid moves anyone know what it is or whatever? My grandma says jus allergies but 🤷🏻‍♂️

[@vivigshanthakumar1840]

excess tear secretion - could be due to allergies. it moves down the nasolacrimal duct.

[@solar3clipse56]

Vivig Shanthakumar thank you and I’m not sure what it was but it stopped but thanks for replying

[@Blackafternoon]

Im way to stoned for this 😂

[@ugonnanlemchukwu384]

median aperture and not medial aperture

[@John-iw1nn]

Intraventricular foremen? WRONG!!

[@jamesfright394]

im unsure what was going on.

[@essandem2790]

Where is the intro music from?

[@bristolneuroscientists1094]

Hi - the music is Andante in Am by Ferdinando Carulli - its credited at the end :)

[@essandem2790]

Bristol Neuroscientists I guess I'm unobservant. Haha, thanks!

[@ElanaVital83]

Well hello uncanny valley...

[@saraa2405]

Lovely video. May I ask what the classical guitar piece played at the beginning is called?

[@martinnm8276]

Yes, I want to know as well!

[@bristolneuroscientists1094]

Hi - its the Andante an Am by Ferdinando Carulli

[@martinnm8276]

Thank you very much lads

[@ritikasharma8935]

He sounds like elihiza from the originals 😂

[@tinokokko3489]

Mitä vittua täällä tapahtuu......

[@Dragontooth2005]

i need to get off youtube now...

[@John-iw1nn]

Shite

[@saifhady8514]

So bizarre animation

[@godsguy13]

Terrible