Genetic Mysteries: FOP - When Bodies Turn to Bone

[@audracourtright6215]

It is truly amazing what humans can live through. I am in awe of how strong these people are.

[@ooffactor]

god help the affected... god help the researchers...

[@IDisnotscience]

I have a form of this. Great to see some advancements in this area.

[@MrPatpuc]

:)

[@IDisnotscience]

Thank you for asking and being concerned. It is greatly appreciated. I have a good life, but I have a form of it. So, my arm has a lot of bone in it keeping it from being fully mobile. Also, some bone in my hand, which keeps it from forming a fist. Certainly not as bad as how most people present though.

[@saradary2700]

I have a neighbor who has it. I pray they find a cure soon

[@myaccount7513]

Stay strong! My heart goes out to you

[@carlosnakashima637]

Ah yes. 3 am content.

[@EffyJones0729]

1:23am lol

[@skysparkler]

CRAP

[@TheVapaaduunari]

53:37 The reaction to amino-bisphosphonates brings to mind the odd function of one sleeping aid that helped bring people out of coma-like permanent vegetative state.

[@alessiakozak986]

This is really interesting to watch! the guy talking looks really tired though

[@myaccount7513]

Always happy to have real educational content right? Lol he's probably exhausted from working so hard to pay his impossibly high rent

[@1396animefreak]

This is one of the 'better' cases f FOP i've seen, one woman had her arm removed (when she was a child) because they thought she had multiple sarcomas , turns out it was FOP and now she's living with both conditions

[@TazSandrin]

Since osteoblasts help build bone, might good to focus on defects causing overproduction and growth causing it to attack other tissues due to collagen content. Either genetically modify a correct version of osteoblasts or help create a correct version of collagen as it seems the collagen is the type found in bones that trigger osteoblasts into actio

[@leosrule5691]

I would try treatment by Dr Bryzneski. As well as the Gerson 'miracle' diet.

[@ihaveautism9838]

leos rule I see what u mean but dr Berg on KZbin has the healthiest diet in the world.

[@UltimatePowa]

Or use weed. My muscles calcify constantly. Dont know if its FOP or something else, its mild FOP if it is, but I just make sure to not stop moving. If I stop using something, or moving in a certain way, thats it, Ill never get it back. So smoke weed everyday and dont stop moving for me. _Like I said, I dont know if its FOP, but I can empathize with their pain because I go through a milder but similar thing._ _For example I have scoliosis, my left ankle is pretty calcified, as well as my left hip, jaw and neck muscles._ _Ask your doctor before doing anything to make sure weed wont cause problems before trying it and DONT SMOKE IT._

[@lemonstealinghorsdoeuvre]

Use weed? Wtf? Think of the consequences of stumbling and bumping into cabinets or any number of foolish mistakes. 🤦

[@lemonstealinghorsdoeuvre]

I got to this from watching "back and forth forever" I haven't seen a path that didn't lead to something the algorithm pushed on me in years.

[@falstoffe]

I wonder if Quasimodo, or the REAL "hunch back" that Victor Hugo based his character upon, had this? The bone formation looks identical, and not, say, scoliosis. Richard III had scoliosis, it's official. Deformed spine but still agile enough to enter into battle and gain a reputation as a soldier-king.

[@123must]

Thanks !

[@leahgardener6759]

Do you think this would be considered a scientific source acceptable for a college paper?

[@joelbackman2702]

yes

[@albertB215]

Of course. This is nothing different to a thesis

[@derpingflamingo]

What grade did you get on the paper?

[@trashcan8672]

I can not imagine having this. I am claustrophobic, and I would kill myself if I couldn't move.

[@lemonstealinghorsdoeuvre]

No, you would _want_ to, but you couldn't move. So you'd have to move to Canada