Glomerular Filtration: Net Ultrafiltration Pressure

For tutoring on this topic, click here: lancemillerphd.as.me/

[@barta5ot-395]

Now this is a guy that really deserves the Doctor title. Hats off

[@Quoted_creations]

Absolutely perfect description with this animation. I can't begin to tell you how much this has help me with that concept

[@BT-vh4lz]

Thank you for taking the time to make the animation and explaining the concepts. I couldn't understand the graph and didn't know how to interpret it until I watch your video. Keep up the good work!!!!

[@Rahafpeace]

Thank you so much this is a very straightforward and clear explanation

[@sujatbanerjee91]

The explanation is marvelous. I liked it

[@mahmooddr]

Thank you so much We appreciate your effort!

[@saminanaeem3112]

amazing animation and explanation.. .keep up the good work

[@Zetsuke4]

Incredible!

[@ZPiiLe1]

Best explanation of this topic I was struggling with it thank you

[@doctord7171]

Thank you so much doctor! you made it very easy

[@irmamaghfirah3219]

Outstanding! 👏🏻

[@user-rb5xz3qu8p]

Perfect explanation.Thankkkkkss

[@chaima184]

Bless you.

[@jajayumi8052]

This is good. Thanks!!

[@dibagabbary2066]

You’re the best thank u

[@dunnuthalayellareddy7618]

Thank you so much sir

[@ayiahassan4533]

Beautiful video :)

[@kimberjaneblake8736]

wonderful thank you

[@ingridmendes6281]

This is perfect explanation, thank you very much

[@LanceMillerPhD]

Glad it was helpful!

[@hussainzuhajamz1420]

Thnku sir😇😇😇

[@adienazoresavhanaj2669]

What is Filtation

[@sunita3734]

Nice

[@DavijazzTV]

Your too deep bro Great job

[@calciclasses]

Speactular... 👍

[@LanceMillerPhD]

Thanks.

[@LOOP931]

🙏❤️❤️❤️❤️❤️ than you

[@ansharihasanbasri]

Fantastic video! I was just wondering if the net ultrafiltrate illustration at the end should actually cover even smaller highlighted area because there's a gap between the bottom line of each P_bs and pi_bs. Rather technical and not rly important (plus nothing's wrong with the calculation and equation) but just wanna make sure I get it correctly. That aside, thanks for making the video. Very succinct and helpful.

[@LanceMillerPhD]

Hi, interesting observation. It's possible that it could be a little smaller in the illustration since we only approximated the calculation in the animation. Hopefully, that wasn't confusing. Thanks for the comments.

[@shanthala1345]

Why does the glomerular capillary Colloidal osmotic pressure oppose the formation of filtrate?

[@poojamourya8030]

I have the same question

[@doctord7171]

When there are proteins in a fluid, they like to keep the water for themselves and this happens in all the vessels. in this case, glomerular capillaries proteins are preventing the water from escaping towards Bowman's Capsule. AKA they "oppose" filtration.

[@shanthala1345]

@@doctord7171 thank you replying , it's been so long I don't remember shit 😭

[@doctord7171]

@@shanthala1345Yeah I bet you are graduated now haha

[@playitback8623]

how can hydrostatic pressure stay the same if there is so much loss of volume that the colloidosmotic pressure increases by about 15 mmHg?

[@LanceMillerPhD]

Hi playitback8623, Good catch, you are correct, hydrostatic pressure decreases slightly as blood moves into and out of the glomerular capillary due to filtration.

[@playitback8623]

@@LanceMillerPhD Hi, can a slight decrease really account for such an increase in colloidosmotic pressure or are there other factors involved?

[@LanceMillerPhD]

Yes. In fact, this can happen when the filtration fraction increases from the typical 20% to near the maximal of 40%. This is referred to as the paradoxical effect. Does that help?

[@playitback8623]

@@LanceMillerPhD Unfortunateley, I do not know about this effect. However, now I know how this is called and I will do some research. Thus, this helps me. Thank you for your answers and videos! Greetings from austria :)

[@LanceMillerPhD]

You are welcome. You are not the first ask this type of question. In fact, it's a challenging topic to teach and it's often tested on the USMLE Step 1 exam. You've motived me to make a short video to explain the paradoxical effect. I'll be posting it by the end of the week. Cheers.

[@calciclasses]

Speactular... 👍

[@LanceMillerPhD]

Thanks.