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This video explains in brief the most important step in the simultaneously regulating glycolysis and gluconeogenesis. Fructose 2,6 bisphosphatase is the central molecule in the regulation of glycolysis at phosphofructokinase-1 (PFK-1) step and gluconeogenesis at fructose 1,6 bisphosphatase step. The concentration of fructose 2,6 BP is controlled indirectly by insulin and glucagon.
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