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Granulopoiesis is the process of formation and maturation of granulocytes, a type of white blood cell involved in the immune response against bacterial and fungal infections. •Granulocytes include neutrophils, eosinophils, and basophils.
•Granulopoiesis occurs primarily in the bone marrow, where hematopoietic stem cells differentiate and develop into mature granulocytes.
•The process of granulopoiesis involves several stages of cellular development and maturation. During this process, the cells undergo characteristic changes in their appearance and composition, including the development of specific granules in their cytoplasm. •Granulopoiesis is regulated by various growth factors, such as granulocyte colony-stimulating factor (G-CSF), which stimulates the proliferation and differentiation of granulocyte precursors. •Understanding granulopoiesis is essential for studying and diagnosing disorders involving abnormal production or function of granulocytes, such as neutropenia (low neutrophil count) or leukemias.
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