Groundbreaking Study Shows Why Is Our Immune System Knocked-out In Winter?

Why do we catch cold in cold environment? (Harvard Study)
These wonderful scientists from Harvard and Cairo have finally figured out why we catch more cold and flu during the cold weather. Let's review this ground-breaking in-vitro and ex-vivo study.
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
URL list from Thursday, Dec. 8 2022
Cold exposure impairs extracellular vesicle swarm-mediated nasal antiviral immunity - Journal of Allergy and Clinical Immunology
www.jacionline.org/article/S0...
Cold exposure impairs extracellular vesicle swarm-mediated nasal antiviral immunity
www.jacionline.org/action/sho...
MicroRNA Mimics or Inhibitors as Antiviral Therapeutic Approaches Against COVID-19 - PMC
www.ncbi.nlm.nih.gov/pmc/arti...
Why colds and flu viruses are more common in winter | CNN
www.cnn.com/2022/12/06/health...

[@leokimvideo]

This Dr should do Children's books. The illustrations are amazing

[@DrBeenMedicalLectures]

Writing one

[@sherylmarshall1444]

Love this !! Stunning pictures thank you for everything you do and sharing

[@kirbywaite1586]

Years ago the British Army did extensive testing regarding this very subject. They were never able to induce a "cold" in a subject by using cold and or dampness.

[@robyn3349]

I was thinking of that, too. Perhaps it is the British nose?

[@yuppers1]

@@robyn3349 Right? They're cold and damp most of the year

[@glennbeard7219]

I would think have been obvious that exposure to cold air made people sick. It may be simply related to humidity

[@BD-3x3]

Right, because the "cold" is not caused by the cold ALONE. What this study is saying is that the cold air makes you more VULNERABLE to a virus; that's not the same as saying that getting your nose cold all by itself will cause you to get sick.

[@BD-3x3]

@@robyn3349 Actually, if you are interested in phenotypic evolution, you can look around and see that peoples indigenous to particular regions in the world do have differently shaped noses, and these likely are related to the types of weather (temperature, humidity, etc.) that they are dealing with traditionally.

[@susanfudge1737]

What about polar bears, Wim Hoff? They seem to prove extreme cold boost immunity.

[@111...]

Ohhhh, great question!!

[@sue.F]

I just love this, great graphics too. Many thanks Dr Been! xx Just as some ancients believed that cockroaches were born out of dirt, my husband believes that cold viruses are born from cold weather 😆 I’ve tried to explain the science to him, but… Anyway, here is an extra layer of scientific explanation of the connection between cold weather and cold viruses. 👍

[@andrewmurphy8154]

The volunteers for this experiment were exposed to cold for only 15 minutes, and presumable spend most of their time in an air-conditioned environment. I wonder if we'd see the same results in people who spend most of their time outdoors and have had time to gradually adapt to the cold with the changing of the seasons. My hunch is yes, but it would be interesting to know for sure.

[@skaterkraines2691]

Hmm, my hunch is no. I am out in cold every day and often figured that was what was keeping me healthy because nose runs almost continually out in the cold

[@CarmenGarcia-bb6lm]

In the old times my grandmother used to tell me no to drink anything cold in the winter y keep it warm inside

[@ShreyanGoswami]

Thank you for the great explanation. It would have been insightful to see at what temperatures the production of EV increases again to normal levels

[@neighborhoodwatch470]

Because more people gather together inside when it's cold. Viruses spread more easily that way.

[@moony77]

Aha! Brilliant!

[@susanfudge1737]

Yes. And lower vitamin D levels.

[@diannefitzmaurice9813]

This all may be so and great info. Although it is great to know the science, it is not necessary to have a study to know what is going on and what we have known for eons. Severe cold affects our ability to regulate body temp and this leaves us vulnerable for the immune system to fight any viruses that we might have been exposed to -- and one of the best reasons to dress warmly with natural fiber clothing. Natural fibers will help to regulate and maintain body temps especially in children and babies that do not have a fully developed ability to regulate temp. An ordinary muffler made from oil based synthetics won't help and is quite useless. Get wool or other natural fiber and make your scarf, face mask or muffler from it . Besides being warm and with great ability to regulate temperature, wool and other natural fibers have anti microbial properties that synthetics do not have !. Wool and other natural fibers also breath and wick moisture so you are still warm even if they get wet ! . Synthetics when wet will quickly lower your body temperature . See the campaign for wool and learn about these and other amazing properties of wool .Wearing wool, not using a nose spray is the best cold buster!

[@breathe.move.perform.health]

I love to see your excitement! THIS IS AWESOME!!!! Thank you very much

[@katherinebaer6798]

Beautiful painting, Dr. Been! You are very talented! In more ways than one.

[@Mary-Mercedes]

THANK YOU Dr. Mobeen Syed! One of the most valuable channels on YT.

[@madinaleon7561]

Excellent explanation of such complicated topic as immunity. Thank you!

[@Jean42ette]

Beautiful painting Dr M :)

[@minkymandy6065]

Wow you're a wonderful artist!

[@brettoneil2782]

Dr Been, I have been wondering whether R/C air-conditioning, which dehumidifies the air, plays a role in drying out the mucosa in nose, throat etc possibly leaving people more susceptible to respiratory viruses. Many people spend a lot of time in air conditioned environments in winter, along with lack of fresh air. As well as deficiency of vitamin D.

[@roisinmc7442]

Yes and central heating drying the air also. I've always thought that

[@lah-tee5412]

I get extremely dried out whether it’s the air conditioner or the heat on and run a humidifier all year round. I’ve also got Sjögren’s syndrome (autoimmune disease) but if I will wake up in the middle of the night if it shuts off because The air is so dry 😣 I can’t really stay over at anyone’s house unless I’ve got a humidifier with me. I know that I’m significantly sensitive but even my “normal” friends have said how much better it is at my house and now they use one too because they’ve seen/felt the difference. I’m not sure what’s going on but I haven’t been sick in the four years of consistently using a humidifier so I know my observation is just anecdotal but i really believe there is something to that

[@mabelheinzle2275]

Beautiful painting

[@happyorange101]

Love this video. Thanks Dr Been. I am curious as to how people in different countries, with different climates, seem to adjust to those temperatures. For instance Australia’s flu season is much warmer than flu season in the UK. I wonder if our cells ability to produce EVs is not dependant on a specific temperature, but based on temperatures that our body has acclimatised to? Humidity also varies, depending on countries.

[@robyn3349]

Thank you!

[@chelseawhite8942]

Wear a neck gaiter to keep nose warmer

[@diannefitzmaurice9813]

Make sure it is wool though .

[@szymonbaranowski8184]

no studies should be copyrighted or paywalled.

[@C2yourself]

Gorgeous painting sir❤️

[@liap1293]

Love your artwork!

[@helenndow1101]

Yes, I got a runny nose ever since I restricted my heating due to the energy crisis but not really a cold thankfully

[@jameskantor0459]

Which country do you live in?

[@helenndow1101]

@@jameskantor0459 the U.K.

[@tomgooch1422]

Excellent sleuthing! Doesn't this also make a compelling case for breathing through your nose? I.e., the little critters are deprived of the elevated body temperature exhalations when mouth breathing. Nose extremities are then deprived of 20+ significant temperature restorations per minute as the nose gets colder and colder..

[@anap1840]

I feel like I may have lived through this just this past week. I was feeling a bit under the weather last Sunday but having no sick symptoms at all. I decided to go for a brief walk outside with the temperature probably just around the freezing mark. Shortly after the walk, maybe within like 2 hours, I started to feel symptoms (body aches and later in the evening a fever). My body was probably already fighting some thin but did that walk outside make things worse? I proceeded to have fever for 3 days and then a pretty bad sinus infection. Now I'm apprehensive about going for a walk outside in the winter 😅😢

[@MK-he1jz]

It's a virus. I'm in wisconsin. It just got here. It hasn't been pleasant.

[@breathe.move.perform.health]

from your take away - the 3000 yr Ayurveda practice of Nasya (medicated nasal oils) I bet help to increase the health of the nasal passage and the EV production and function!

[@tammygravis1462]

How amazing to be as smart as you. I wish you'd do a video of tests to take for the vaccine injured. Fasting is helping me so much.

[@2002ZRX1200R]

Temperature doesn't effect my health, so far.

[@ceilie1]

Same here :)

[@diannefitzmaurice9813]

Where do you live ? Do you have central heating? What is coldest temp where you are with wind chill?

[@2002ZRX1200R]

@@diannefitzmaurice9813 OBX, temps seldom drip below 20, but I've seen -5 windchill, but I've lived a lot of places, temps and elevation and never had an issue with temp causing issues.

[@denome]

I don't think the study outright proves that cold air takes out EVs. Two unanswered questions: 1. What happens to EVs if people go back to hot air from cold air? 2. What happens if people stay in the cold air for prolonged periods of time? It could be that there's only a small window where the EVs are lowered due to a sudden change and body readjusting to the new climate. Also it is common to see colds and flus at the beginning of a season change. So people who get repeated exposure to cold and hot probably develop resistance to this effect compared to people who you expose to cold air for the first time in a long period of time. This would also explain why people who do cold showers daily typically have avoid diseases more as they're constantly experiencing that hot/cold fluctuation. Just my hypothesis...

[@lilolmecj]

Vitamin D, relatively dry indoor air as a result of heating practices, indoors more of the time, ( that one is not as pertinent in the modern era, many people only get outside the bare minimum, some not at all). Those are the factors I immediately think of.

[@KaylaHearn]

Question: in the context of covid binding to ace2 receptor, in warm temperatures, theoretically it might not be a good idea to use ace2 receptor competitive inhibitors?????

[@brockdelorenzo1120]

My guess is that it involves magnetism. Pressure difference between lows and highs and how they effect the body. Similar to using magnets on the body, etc. lots of research on plant growth with magnets. The body is electric and can be altered with magnets.

[@micahbarbee8636]

What about a spicy sort of soup?

[@multivariateperspective5137]

Yeah this one seems to miss a lot of fundamental primitives involved in the factors here, but interesting Datapoint there are a lot of counterpoints a differential would need to be done on both extremes to find the real causation and limiting/enhancing factors

[@susanpick2382]

😁Coming from a cold Country...Mom always kicked us outside to "blow the stink off"(her words😉) in wintertime -30C. Apparently we swapped too many germs "cooped up" in the house and she had to clean it.😄...if you had a runny nose, you better be washing your hands more, especially after wiping it. If we were sick we were slathered with Vicks Vapo rub on our neck and chest, and necks were wrapped with my younger sisters old, cleaned diapers, complete with the diaper pin...so we couldn't get stabbed by the pin if it ever opened. Still use flannel to wrap up with when sick😉. Hey, they need to do a study on what Vicks vapo rub does to germs in the nose after breathing that in all night...its a staple in just about every Canadians home along with Buckleys Cough medicine??

[@guytelfer1353]

Any percentage of iron?

[@tgmylefttonguetoo5073]

nice painting

[@jjperry3995]

In TCM they hypothesise that the virus enters the back of the neck so it is important to have a scarf or neck sock to keep the neck warm. That would help raise the temp of the blood in the nose and help to keep it warm.

[@manehbag732]

What's TCM?

[@jjperry3995]

@@manehbag732 Traditional Chinese Medicine.

[@TheBiochemist1]

Are we able to design these micro rna ?

[@leopoldsoderpalm-berndes3599]

Can those EV´s be increase in the nasal mucosa by doing sports in the cold, maybe through increasing the overall blood-flow in the nose? What comes to my mind is that when I am jogging in winter (cold) times I only breath through the nose. The cold hurts at first, but after maybe 5-10 minutes the blood-flow into the nose increases and warms the nose.

[@TL-ch1xd]

So therefore people in colder countries are more often getting colds? Or does the body system’s in those who live in cold climates learn to self protect in any way?

[@margaretneanover3385]

Was university or collegiate school really In Egypt, Harvard was one private school. Curious to hear..forgive the spread of miscommunication

[@runfrankfurt]

If I just wear a pair of socks for a few days and then wrap it around my nose to use as a nose warming sock: will the cheese odor scare away the virus or kill it passing through the sock? (apart from the fact that I might pass out due to the smell of course)

[@guytelfer1353]

Right, this causes sneezing

[@thegoru0106]

Why would the body do that to the EVs in cold weather? There has to be some kind of evolutionary explanation or is it just a bug of our system.

[@sstorm1328]

As a northerner, I never get colds or sick from spending time outside in sub zero weather all day... And I find I get better faster too if I'm outdoors most of the time. I only get infected or sick in indoor warm environments from other people.... Of course because there will always be a higher concentration of happy viruses in that environment too. Good study but does not answer a lot of the questions raised here in comments. And the study seemed really short (15 min) and maybe zero effect in a study 60 min longer... Very controlled study and if it is like a lot of studies today the data might have been cherry picked. The real interesting part of study is the revelation about what EV s can do. Maybe they do a lot more thought.... If the study had been longer or with changing environments.

[@cdeets1138]

What if a person is IGA Deficient?

[@ggordon4127]

What about those that breath through their mouth not their nose?

[@glennbeard7219]

I think it would have been obvious by now that exposure to cold air caused viral infections . It is more likely to be related to humidity

[@traviscampbell5023]

I know people that like to "cold plunge" and they claim that they do not get sick as often. Is it possible to frequently, briefly, expose ourselves to cold and train our body to increase the amount of EVs? Not sure if the study look at EV quantity over time.

[@guytelfer1353]

Cold air itself causes deregulation in thermostat possibly resulting in a fever, slowing mucosal response

[@Raj.Sakaria]

Takeaway. Heated masks, wear scarf

[@xDomglmao]

4:08 "patients on drugs" => I guess this means immunomodulators? or do you mean addiction in e.g. homeless (but that would rather be socioecon, right)?

[@dieZera]

huh? saw this video this afternoon already but didn't come round to watch it yet was it gone?

[@DrBeenMedicalLectures]

Had to move it from live to videos section.

[@dieZera]

@@DrBeenMedicalLectures ah 😊 thanks for all your efforts, love your lectures

[@jyothirmai9990]

When 😀he said normal civilian cells I can't stop laughing

[@user-ju2yb3ng6c]

Is a mask considered a 'nose sock'?

[@derek4612]

I think that's why alcoholics practically don't get colds🤔

[@charlespratt8663]

Or you get less sunshine exposure in winter and your vitamin D3 level drops.

[@guytelfer1353]

Masking makes nasal warmer

[@Notarealusersname]

Sounds like support for masking in cold environments. Is there evidence that cloth masking increases your chances of getting sick? I had seen one paper that seemed to suggest as much.

[@jjperry3995]

No drugs. Sorry. Neck sock it is.

[@udodonau4609]

the basic assumption is wrong, so the rest is worthless