Growing Living Rat Neurons To Play... DOOM? | Part 1

[@thethoughtemporium]

Over the past year we've made some serious progress on this project, come check out Part 2: kzbin.info/www/bejne/mV7TiJ-fqsuobLc

[@GamePilLP]

Great video, watching it before the part two! Btw, do you know what movie/show is the clip at 0:56?

[@Xnoob545]

Ok

[@thethoughtemporium]

@@GamePilLP They're Made Out of Meat: kzbin.info/www/bejne/baW2lHSvg8aFmrM

[@GamePilLP]

@@thethoughtemporium Many thanks. Can't wait for the next part

[@SunShineForTheFine]

The fact that human neurons are so advanced that they can force other neurons into playing doom for them is crazy

[@A-Milkdromeda-Laniakea-Hominid]

Makes you wonder, what we're doing for some 4th dimensional scientist using 3D spacetime instead of 2D glass discs for growth media.

[@littletimelord2755]

Ya know, you bring up and interesting point. Imagine how these other neurons feel, they must think we’re quite audacious to do experiments like this

[@PHneverwhere]

You gain conscousness just to reap and tear rhose demons

[@KinuTheDragon]

Crazy? I was crazy once.

[@harrisfh]

@@KinuTheDragon They locked me in a rubber room. A rubber room with rat neurons. Rat neurons make me play doom.

[@rubenflores1200]

Rat neurons “What is my purpose” Scientists “You will play doom” Rat neurons “Sick”

[@kennyoffhenny]

😭

[@JmKrokY]

Fr

[@ODST_TROOP_ON_BREAK]

TBH, that is pretty f***ing tight. 😤

[@cleptuno]

“You can also pass the butter, once you get killed“.

[@FuS3D86]

Rat neurons "Do I get cheese?" Scientists "No... you get a tone generator"

[@Cry0fwar]

Imagine gaining consciousness for the first time and your just Doomguy

[@realbrickbread]

*you’re lmao this has just become a giant meme in the replies

[@robloxarchiver]

@@realbrickbread yuo're

[@codatheseus5060]

Yore*

[@theevil_Dem0n]

*er’uoy

[@m.i.c.h.o]

*yur

[@arthurcallahan6108]

“Ah sweet, man made horrors beyond my comprehension!” -Peter Griffin

[@ivonnesaysmiau]

wonders*

[@michaelerlanger2797]

Me seeing horrors beyond my comprehension (I don’t get it)

[@FrosstKatt]

"well i can comprehend these manmade horrors perfectly fine so idk maybe you have a skill issue or smth" -scout tf2

[@FinnCrossan]

It's nice to think that someone's thought process while looking at a brain was "but can it run Doom?"

[@nathangamble125]

Well, it's _playing_ DOOM rather than _running_ DOOM. My brain can also play DOOM, but can't run it.

[@idioticlight]

@@nathangamble125 quitter mindset

[@kevynpacthatguythatdraws]

@@nathangamble125 you're technically running doom if you're thinking of doom.

[@leafly7917]

​@@nathangamble125🤓

[@kaiserofyoutube]

@@nathangamble125 nerd

[@togglehd]

He really took "But can it play Doom" to a whole new level!

[@goofoffchannel]

Can't wait for down the line when it inevitably runs skyrim

[@TheDrakanMaster124]

But can it run crisis

[@pumbi69]

I think you got doom confused with crisis. Doom can even run on a toaster

[@TheDrakanMaster124]

@@pumbi69 I play Doom on my TI-89 titanium

[@suisse0a0]

Well, it is know Doom can be play on anything... he just keep the trend going and true!

[@gabrielwolffe]

"We're building a meat-robot"..."we're training it to play DOOM"....I see no way that this could end horribly.

[@TooLameToDie]

something, something, Skynet. Something, something Armageddon

[@onewithsource9742]

😂🤣😂 You guys! 😉

[@Barrel4336]

Hey, there won't be no problems.... unless a portal to hell opens up on Mars

[@onewithsource9742]

@@Barrel4336 all because Douglas Quaid blabbed about Mars. Smh

[@wizard_bunny]

Maybe it saves us from the Demons coming through the portal

[@GlobalWarmingSkeptic]

Imagine getting stomped in an FPS and it's just an array of a few hundred neurons that owned you.

[@Beta_Mixes]

Well, technically this was always a thing

[@MaxJ.ProfessionalLilGuy]

I wonder if the Petri dishes will be capable of typing “I mitosed ur mom loser” in game chat…

[@OMalleyTheMaggot]

Haha i can only imagine... *cries in TF2*

[@bigshot103]

Imagine loosening to something with millions if not billions less neurons than you

[@skepolotv4173]

Who would win? Experienced pro gamer with decades playing a variety of shooters vs. a neuron blob

[@stuff31]

I like that this guy's first thought when creating a sentient being is to make it play doom as if "can it play doom" is a benchmark that should apply to living organisms and not just old computers

[@Kishmond]

This is less sentient than a small insect.

[@StormsandSaugeye]

@@Kishmond *But can it play doom?*

[@nicolasherrera0]

@@Kishmond It's more sentient than a tardigrade?

[@ricecooker7037]

@@nicolasherrera0yeah well giving the neurons positive output is like sex for them so they’re having a goddamn party.

[@plumeria1985]

@@Kishmond and? Would you trust an wasp smart enough to play doom? I think not.

[@acetylsalicylicacid]

Imagine frantically running home, but instead of, "I left the oven on!", its, "I forgot to feed my computer!" 💀💀

[@exered-pc8hg]

Warhammer be like:

[@Deadchannel_321]

bruh💀💀💀 this is funny asf💀💀💀💀💀💀💀💀💀💀

[@Zacc2001]

Mom: remember to feed the computer!

[@Scruyum]

And then it becomes conscious

[@darey8321]

Wow a TF2 emblem haver

[@DefaultFlame]

Pitting miniature clone-brains of the lab personnel against each other in a quake tournament is the most mad scientist thing I've heard in real life.

[@alexkha]

yea, why not choose a more peaceful game? Flappy Bird? Tetris? Pacman? Sim City?

[@michazadkowski8516]

​@@alexkhastellaris

[@dgurevich1]

​@@michazadkowski8516ah yes 'peaceful'

[@michazadkowski8516]

@@dgurevich1 it is peacefull after xenos are gone

[@arekrekas213]

most of the games you listed are singleplayer only one that's multiplayer is Tetris, and even then matches of that can get pretty sweaty all things considered@@alexkha

[@the_soggster3464]

What someone will say 100 years from now... "awe come on dude, he was 1hp and then I started lagging, my computer must be hungry brb."

[@neoleonor7140]

it's atleast like a 100 bucks for a Iphone 30

[@Jumboo-j8e]

The fact that only a few neurons are needed to play Doom is a reason for this games success.

[@karameelch]

bro😂

[@Jumboo-j8e]

@@BB-wl4qz 😜

[@JackPonissi]

Lool!

[@mhyotyni]

If unnamed kid brother could play Doom succesfully in 1990s, there is nothing to wonder if a couple of rat's brain cells would play that game better! 🤤

[@roastedflesh]

Neuron Gaming

[@williamprice7364]

We need to get a rat neuron speed run community

[@frfrough7088]

Shesh, you've got my laugh

[@ChrisP-c3d]

Logical next step

[@aaronthecatten]

lmao

[@Atoyihrs]

Are YOU faster than a bunch of rat neuron!?

[@rebeccaconlon9743]

Rat%

[@Freakshowed95]

I’m terrified of the idea of severed brain cells learning to circle strafe at top speed and proceeding to play the game with the skill caliber of a professional speedrunner

[@sa2-2k14]

This is already happening with machine learning, which is literally bruteforcing any possibility simultaneously by abusing the ridiculously INSANE computational power of hardware

[@Freakshowed95]

@@sa2-2k14 i know, but that’s a machine emulating the human ability to grow and learn. I’m talking about organic material severed from it’s original environment learning how to do the same kind of stuff on it’s own without any kind of assistance from the rest of the body it originated from. THAT sounds like brain-in-a-jar kind of stuff, which is exactly what this seems to be, minus the brain itself.

[@beebo33]

I'm thrilled by the idea

[@Beepers559]

The first artificial intelligence made of flesh

[@wta1518]

That already happens, just with non-severed brain cells.

[@crapchannelbruh]

Computer: my brain hurts, can we play later? User: no

[@jugel4533]

You're doing litteral scientific studies and present it as a KZbin funsie to fund it, you have my utmost respect

[@brutuschapman2508]

This man is grinding out meat robots and getting paid. The grind is real.

[@SixWatt]

@@brutuschapman2508meat grinding

[@LightPink]

I didn't see anything that indicates this is a study

[@jugel4533]

@@LightPink because there isn't, but when you're doing cutting edge research like that, even if you don't publish afterwards (and nothing point to them not doing that, this seems more than worthy enough), you're pushing the field forward.

[@brutuschapman2508]

@@SixWatt put ya head in the meat grinder 🤌

[@piorewrzece]

If this end up taking over the world I better tip it. Who knows maybe it would remember me in those tiny neurons

[@Nov1cegg]

Hey, just for insurance purposes, I love you tiny neurons

[@samijacquin8814]

i get basilisk of roko vibes here ...

[@aakashsahani2991]

"You can grow neurons from skin cells" I certainly need to do that to myself

[@vanconojl]

xD

[@orthotron]

Too much skin and not enough brain?

[@MatthewConnellan-xc3oj]

@@orthotronyes

[@catatoblob8598]

That's terrifying. Most people have "just enough skin"

[@orthotron]

@@catatoblob8598 you can harvest your own skin, just let it grow back each time

[@maximusheaton8375]

Pretty sure this is what Mary Shelley was trying to warn us about when she wrote Frankenstein

[@puppyqueen5688]

No frankenstine was about not being cruel to people who look different

[@appletunisheccincute6253]

But can Frankenstein's monster play Doom?

[@maximusheaton8375]

@@puppyqueen5688while yes, that’s a very surface level interpretation. Mary Shelley was a romantic who opposed the enlightenment, Industrial Revolution, and heroic era of medicine. Frankenstein was written as a ‘cautionary tale’ about the dangers of pushing science too far which was happening at the time. The monster is a physical representation of the horrors that happen when science is pushed too far, these horrors (the monster) eventually catching up with humanity (Frankenstein and his family being killed)

[@willambernahecooking4036]

Nope. Wrong. She finished Frankenstein in 1817. DOOM was released in 1993. Mary Shelley never played DOOM.

[@lamechial]

@@willambernahecooking4036No way, really???? I thought the first installment of DOOM came out in the 1800s!!!

[@mekingtiger9095]

Honestly, the concept of growing actual organic brains, even minituarized ones, with just a few cells or loose tissues grown artificially out of an actual organism to do tasks or control a computer sounds FAR more terrifying than the digital AIs...

[@subbot8077]

that’s basically the plot of Bladerunner lmao

[@weirdojo2392]

It's conceptually uncanny

[@GodOfLovers1111]

Yes

[@DaTLMusic]

​@@subbot8077you mean psycho pass right

[@shweedy_]

its not terrifying, its exciting

[@RepDreStre]

I taught human neurons to play Doom by playing it myself

[@KadenHartley]

Booooo. You suck

[@Godly_Improvement]

true.

[@Tanystropheus10]

No you didn't you taught them how to pilot a mech to press certain buttons that translate into certain actions and you choose what actions to do based on sensory signals based on light wavelengths (eyes) Very different

[@RepDreStre]

@@Tanystropheus10 Yes I did. It took me like 6 years to master this body. I'm amazed you've heard of my other endeavors. Are you perchance a fan?

[@protocolsavage8506]

@@RepDreStreteach me how to pilot a mech broh pls

[@puppetmon9687]

Damn, Doom truly is the universal videogame, it can be played in anything that can generate electricity

[@BassoeG]

Too limited, someone ought to see if they can run Doom on a clockwork Babbage Engine.

[@TheLostBijou]

Well, there are A FEW requirements...but...yeah.

[@lilliecelestedavis7968]

making the biomechanical brain ai orgasm every time it kills something couldn’t possibly go wrong

[@maosephxingstalinping6510]

Skynet

[@peppermintgal4302]

​@@maosephxingstalinping6510 Skynet, but with a xenomorph for a brain. :D

[@maosephxingstalinping6510]

@@peppermintgal4302 Make this a movie

[@randomspartanhoe4501]

"orgasm".

[@WetAdek]

​@@maosephxingstalinping6510just a movie? I'd say make it reality.

[@miss_bec]

These man made horrors are within my comprehension and they're really cool

[@Tiziotozio01-cz1nd]

Nevermind

[@MouldedMind]

@@Tiziotozio01-cz1nd your grammar is beyond my comprehension

[@kaanthereaper256]

Man made horrors are the best ones

[@thearpox7873]

I can't wait for the lab-grown brain to face off against a supercomputer.

[@GruppeSechs]

@@Tiziotozio01-cz1nd I'm with you, man. This video was just kind of disturbing to me, when I think about the implications in the decade to come.

[@azraelcorvo9087]

I didn't realize until the start of this video, but a meat robot is basically a homunculus. Crazy how sometimes science loops back abound to its historical roots in alchemy.

[@dejavuism]

If this is a homunculus, then so are things like ChatGPT and all the other AIs. Hell, our CPUs and GPUs probably count as well, with the amount of 'neurons' and 'connections' it has. This video really had me thinking on the nature of conciousness and humanness.

[@azraelcorvo9087]

@dejavuism I'd say current AI tech isn't really anywhere close to complex enough to be considered conscious though. And while a GPU might have a lot of connections, I wouldn't consider it a homunculus either. I think the meat robot is close to the idea of a homunculus because of its organic nature, what with alchemical homunculi being artificial humans and all.

[@DG-iw3yw]

well, the capabilites lie in different areas, the brain is more complex and powerful than our ai, yes, but ai is seldom delusional or willfully ignorant id imagine too...Plus human error and all its nuances

[@idontwantahandlethough]

@@DG-iw3yw I was about to [jokingly] say "uhh I'm pretty sure ChatGPT has been both delusional and willfully ignorant"... but if anything, that actually reinforces your point 😂 (and to the inevitable nerd that comes along to tell me that chatGPT wasn't _actually_ delusional or willfully ignorant: shut up. just.. shut up )

[@cowsrbeefy]

styropyro quote

[@Marzipannn]

Adding "making home grown brain cells remember doom mechanics" to my list of man made horrors no longer beyond imagination

[@BiggityBoggity8095]

Putting here cuz no responses OP is factually wrong when he says that doom is only 2d. The game is legitimately 3 dimensional.

[@Mrree250]

Imagine what governments around the world are doing in a deep dark lab somewhere

[@Natsukashii-Records]

@@Mrree250 Remaking old non threatening dog viruses into human-spread diseases?

[@Mrree250]

@@Natsukashii-Records ☺️not the government silly! They would never do such an awful thing

[@mohandamrouche7470]

@@BiggityBoggity8095 Okay can i have your truth about what you claim ?? Because i never played dooms but have digg into a lot a video that explain dooms ! And to what i know it is not 3d at all ! Only 2d image pre selected through the view of the player to only render a multi 2d image "collage" or paste together ! That why dooms can be play on a electronic pregnancy test of even electric thermometer ! And if you say well there is stair and level .... Well yes but it still in 2d ! When you use a elevator or a doors sometime the game teleport you to a another location in a 2d map ! what you see is only a 2d rendering and the clever trick of John carmack (wich is not is own idea there is a github explain the code to anyone with a goode levl in math ) is to only a reverse square formula to skip the impossible 3d rendering they were aiming to do ! Just think about it it was a time were Graphic card wasnt even at 1gig of ram for the randoms pc owner ! But i'll be more than happy to be wrong and learn a feww things about it ! But i'm sure the first 3d engine weren't 3d at all and use a trick to rendering false 3d ! You know that's why you can't have bullet impact on the wall or smoke grenade ... it's particule rendering or 3d object with own physic wich the game can copy and lie about but can not do by the way redering doom is ; Just like the video say the game is 2d :/

[@mehreganzare7658]

This video made me cry. Thank you, you give me hope that although I'm stuck with a crappy lab and professors, there are still real scientists out there doing real scientific experiments.

[@gunkwizardry]

I totally feel this, currently taking gen chem and my lab instructor is awful

[@ruff1e]

At this point the doom community will overtake the science community technologically very soon

[@swalke6861]

Can we play doom inside our eyes find out in 10-50 years

[@thespaceman8231]

Can we play doom in our sleep?

[@johnconnorstopskynet]

Thats when the interdimensional gates to hell will open for real lmao

[@doomtrooper3184]

And the Divinity Machine will exist... Probably.

[@ulamoggyre958]

@@thespaceman8231 yes

[@zoz2124]

As a PhD student in biomedical engineering focusing on stem cells and blood vessel organoids, this series is a awesome to watch and gives me a lot of ideas to try!

[@jan-Sopija]

oh no a smart person

[@starblight22]

I find this stuff fascinating, i have one more year of high-school and plan on going into biomedical engineering, i feel i know what it's about pretty well but I'd love if you could spare the time to explain some of the things you and/or your colleagues do in as much detail you seem fit. Thanks in advance.

[@jan-Sopija]

@@Jason-rp3jg no but they might actually do something with this idea instead of "can you run doom on a brain" (and j realise that theyre making the brain cells play doom instead of run it I used 'run doom' to emphasize the meme origin of this)

[@beaclaster]

oh no I'm scared of what your ideas may be

[@starblight22]

@@jan-Sopija yeah like helping paralyzed people interact with the world in unique and useful ways. The applications of using cells with computers and stuff as well as modifying them are endless.

[@AppliedScience]

Fascinating work, man! I'm really glad and impressed to see your progress.

[@TheLonelyStreetLight]

“Though unlike the missile the array doesn’t know where it is” bro I just got flashbacks of that missile meme

[@kingmonkey460]

This is absolutely stunning on my opinion. The fact that this can be a real, living thing with very primitive intelligence, and it learns how to play a geme. But at the same time, this is funny because just imagine you wake up and you're just Doom guy

[@Twekion]

This is what the neurons are experiencing "You have been selected to become Doomguy!" "Huh, what???"

[@elfstar7514]

@@Twekion what if neurons could learn to make KZbin comments. anyone one of us could just be a pile of bottled robot flesh and no one would know

[@manuell3505]

It's highly exaggerated. Most functioning, like the idea of aiming and firing is based on binary computer logic. Only dedicated decision-making might add a tiny bit to what otherwise would be a program with some RNG-trickery.

[@armanazmiibnamin1108]

@@manuell3505 You missed the joke buddy 😅

[@manuell3505]

@@armanazmiibnamin1108 And that is? Calling bs...

[@Cesar-ot1xk]

New episode of manmade horrors beyond my comprehension, good work, greetings from Spain

[@timmutaja5687]

I think that the explanations are quite excellent, therefore making them man-made horrors within my comprehension ://

[@Ennarmreal]

I'm so sorry, hope you make it out of there

[@uis246]

Noone expects Spanish Inquisition

[@Soul4007.]

Arriba España!

[@Gsus__17]

Sabes de algún canal o blog sobre ciencia neuronal o organoides neuronales en español? El tema me parece alucinante

[@davidcotham1939]

Imagine having different batches compete against each other in Quake. Then through years of tweaking and improving generations of this, you create the ultimate force of gaming neurons.

[@Dengar97]

Or you could take the best specimens and turn them against actual people to conquer the world.

[@LtdJorge]

​@@Dengar97they would only know how to play Quake, tho!

[@accuratehvacr]

Ultimate war machine

[@Darth_Bateman]

@@Dengar97I don’t want to take the best specimens and turn them against actual people, Spider-Man!

[@przemysawnowakowski]

And then release them into multiplayer

[@cream5439]

babe wake up new horrific state of consciousness just dropped

[@Nerdnumberone]

How complex does an array of rat neurons have to get before "negative reinforcement" becomes "pain"?

[@Nerdnumberone]

Also, does using human neurons matter at this point, or is it more a matter of how many neurons you can cram into it?

[@the_devolper]

@@Nerdnumberone I would assume human neurons are better at doing what they do because they need to organize in a more complex way in the brain and so they are better at creating useful connections... As for the pain thing I think that you would need to have a real brain to have the "pain problem": it would have to be really complex to begin suffering I think, and also if you tune the system right even if it had self consciousness (that I think is needed to suffer) you would not need to make it really suffer: it's enough to make an error create an unpleasant situation and a correct response a pleasant one I think, no need for pain

[@coyotedomino]

@@the_devolper all things suffer, on with the torture

[@tennicksalvarez9079]

@@coyotedomino brutal bro brutal.... Love it

[@feuerling]

A brain can't actually feel pain. It would need pain receptors.

[@JustWhyFFS]

Think we've finally taken the old "yea, but can it run doom?" meme, far enough

[@blackshard641]

lol

[@Numbabu]

Can’t wait to get the new doom port installed in my frontal cortex

[@Paul_Bedford]

No. Until we design the universe to play doom, we will never be finished.

[@BobbyBlockable]

They were so focused on seeing if it could run Doom they didn't stop to think should it run Doom

[@twistedyogert]

No, that would involve removing someone's brain and spinal cord and using that to play Doom.

[@thetheinen8419]

I don't think Carmack or Romero could have ever have predicted that people would do this with their game

[@dkskcjfjswwwwwws413]

carmack is from the 5th dimension he already knew

[@jacklansdale77]

Incorporeal entity John carmack knows everything.

[@VaImorian]

Halfway through the video I forgot the whole purpose of this video and was just really fascinated about it all and then I was like "wait this dood is gonna play DOOM on these things lmfao"

[@toul100]

The fact that the last living memories of this rats brain is quite literally a hell on earth is crazy.

[@robinvegas4367]

*mars

[@SobeCrunkMonster]

a bundle of neurons is not going to be formulating conscientious memories or thoughts or feelings.

[@chilling_at_pontiff]

​@Nobddylet me lower your neuron count to >2000 ,and see how much you remember

[@noahboucher125]

​@@chilling_at_pontiffThe number of cells has very little to do with their function. A dog's brain is way bigger than a rat's, but they aren't significantly smarter.

[@Bumblebee2361]

​@@SobeCrunkMonster I was actually pretty worried about this. Thank you.

[@seleckt6600]

Ah yes. One more step towards servitors and man made horrors beyond our comprehension. Excellent work.

[@rinoksilpshiknimenyaa]

Black mirror for real

[@realxrust]

@@Fangyuan838you reminded me of the SOMA game, you should probably check it out if you haven’t. Touches upon storing your mind as a file.

[@sofieselene]

Man made horrors beyond our comprehension - or wonders beyond our comprehension. It just depends on whether humanity continues to value human/sentient rights.

[@davidf2244]

Sick. I don't believe experience is sacred if it even exists in some meaningful way. So bring it

[@wyldelf2685]

Remember the AI replicators on StarGate SGI ???

[@natecus4926]

The fact that you explain it in a way that makes me feel that I can do this shows that you are an amazing teacher

[@Imperial_Lizardgirl]

Actually you can. (Buy Starfield)

[@sldtyp0]

Ok so this video taught me something. I have ADHD and get Overstimulated A LOT and when I do it’s chaotic noise and unintelligible yelling. The noise is chaotic and you said that neurons naturally try to avoid that and i definitely avoid being overstimulated so I bet that my brain is trying to get me to un-overstimulate myself

[@hollypixie4285]

Have ADHD and can confirm. When I get overwhelmed, I describe it as my brain going "AAAAAAAHHHHHHH" repeatedly and forcefully.

[@sldtyp0]

@@hollypixie4285 yeah it’s like that for me plus like static

[@jayeisenhardt1337]

@@hollypixie4285 Do you also see cowboys singing in the sky?

[@matthewpritchard9777]

i remember watching the rat cells control the flight simulator like 17 years ago on the science channel. i'm so glad that you have revived this and brought it back to people's attention.

[@socialgutbrain7774]

That was 17 years ago?! Holy shi

[@matthewpritchard9777]

@@socialgutbrain7774 apparently it happened all the way back in 2004

[@firek9195]

@@socialgutbrain7774 we are far behind actually development of science

[@eldiospalomo2334]

​@@matthewpritchard9777then it happened 19 years ago

[@thearpox7873]

@@firek9195 What do you mean by that?

[@jackpfefferkorn3734]

Everybody was asking "Can it run DOOM?" But nobody thought to ask "Can I run DOOM?"

[@goodguycarl]

e1m1 starts playing (in my mind)

[@The_OwO_Shogun]

Can you?

[@Hexagons7]

@@The_OwO_Shogun yes

[@hiphyro]

i think if you can play doom you can run doom because you're experiencing it which I think would mean you're simulating what you're experiencing in your head (to some degree)

[@apIthletIcc]

The answer is yes.

[@bunsenn5064]

Imagine creating what is essentially a completely organic supercomputer just to play Doom

[@superlexaan_]

You might like playing Rain World then!

[@superlexaan_]

You might like playing Rain World then!

[@PoopooTf2]

You might like playing rainworld then!

[@psychicchicken5263]

You might like playing Rain World then!

[@basicmudkip5985]

You might like playing Rain World then!

[@jaymikevillanueva1212]

I recall in Star Trek, they have something called bio-neutral gel packs. The concept is that neural-based processors which allow "fuzzy logic" for faster processing time. This is cool.

[@RandumbPersun]

3 questions of the internet: Can it play doom? can it show bad apple? can it sound out megalovania?

[@Alexandrek1922]

Can it rick roll

[@vonelgamer3071]

Can It Squirt?

[@unknownvariable2456]

You forgot one Is there p*rn of it?

[@Shinkajo]

Does it blend?

[@Swagpion]

Bad apple is the least impressive, megalovania requires some effort, and doom requires the most computing power.

[@thewizardtk]

Imagine a whole room filled with irrigated brain mass used as an advanced AI system… Kind of horrific if you think about it

[@kylehankins5988]

Yeah it would be pretty fucked up if that thing was actually sentient, if not I guess it’s fine

[@benjaminmiller3620]

Read any Peter Watts?

[@soldierinsane2689]

There’s so much potential here, this development could usher in a new age. Giant mother brain computer mechs

[@jacobydotwin]

imagine playing the next cod game in 2074 using a gaming pc with brain matter in it

[@maxk5065]

you mean "psychopass"?

[@barry6541]

Now you should turn it into a computer that can render a CGI spinning rat

[@TheGuyWhoComments]

Make the rat make a program architecture capable of making architecture to create more rat programs

[@kentozapater8972]

Imagine you just gain consciousness and you see your rat mother spinning into the void with a tpose

[@TheGuyWhoComments]

@@kentozapater8972 for all you know I’m actually spinning rat that’s been given KZbin access

[@Partyturtle357]

I USED THE RAT TO MAKE THE RAT

[@TheGuyWhoComments]

@@Partyturtle357 yes

[@relixnova251]

Aw sweet man made horrors beyond my comprehension *sick heavy guitar riff*

[@robertfletcher1871]

Hold on, so the old-school sci-fi 'brain in a jar' concept might actually be possible? I feel nervous, yet intrigued...

[@KaizokuSencho]

"Arrooo" - Nixon's head

[@The_scrongler1978]

I’m gonna turn into a robobrain

[@MagnetizedBread]

lol

[@kekekessa]

The brain in a vat is a philosophical thought experiment and while certainly interesting, shall remain as such for quite a while, as keeping a mammalian brain alive in vitro would require some substantial leaps in science - not even mentioning the ethical concerns. Grown neuronal networks have nothing compared to the highly specialized cell types, nuclei and networks (and much more) we possess.

[@Weldedhodag]

​@@kekekessashut up im gonna be a cool robot

[@s.r.howell1297]

I've got a feeling that DOOM is going to be a test of choice for the next 1000 years.

[@muguly4591]

In the next 1000 years humans will be the test choice

[@ClancayCargo]

@@muguly4591we already are the test of choice.

[@muguly4591]

@@ClancayCargo yeah but it's getting worse and worse and people are going to normalize it and then we're screwed

[@Stetch42]

That or Skyrim

[@Pablo-zx6ki]

Doom is eternal

[@TheGroundedCoffee]

This project is unsettling in the most exquisite way possible and I love it. Giving off heavy "I Have No Mouth But I Must Scream" vibes.

[@therealspeedwagon1451]

Imagine if a super intelligent AI exterminated all humans except for a select few and they genetically modify them into living computers to live out the pain and suffering of being made up of several trillion wires spread out across several kilometers. That’s what I Have No Mouth And I Must Scream is. Seems like something fun the Qu would do though.

[@TheGroundedCoffee]

@@therealspeedwagon1451 exactly. It brings the 'living in a simulation' hypothesis very close to home and I guess that is, to me, the most unsettling part. This isn't fiction, this is becoming reality, right here and now.

[@hexagon2185]

tbh, it isn't as horrifying as people seem to make it out to be. After all, we're literally masses of neurons.

[@50zezima]

I guess maybe because ive experienced ego death before, I realize how extremely uneducated and ignorant you people are in the scheme of things. Just running in circles, killing things and torturing for eons and eons... Then being killed and tortured by those same creatures... Literally never learning from your own mistakes. Because you are unintelligent, and cringe.

[@sirllamaiii9708]

This is cruelty squad irl

[@hackmaster124]

It's cool you guys are using Intan. I do neuroscience research at a university and Intan is our go-to for ephys stuff. The RHS system is really nice being able to stim and record at the same time. The amp settling rate sucks though, it's like half a second before the recording signal is reliable. We go through a lot of those headstages because we use them with awake rats. Gotta love those NIH grants XD

[@Chris06660]

the first ever lab grown brain tournament sounds incredible, and I wanna be here for the day that happens

[@irmatroll]

He's going to Prestige himself into a jar. Worse, he's going to convince his lab partners to join him.

[@irmatroll]

@@Jason-rp3jg most people today would likely be uncomfortable with the notion of grafting a human brain permanently into a computer. Especially in this format, where it's freedom is so dramatically reduced.

[@thechazz3230]

​@@irmatrollIf he and his partners don't have the morality and self control to stop themselves from doing this. They need to be involuntarily hospitalized. They are not well, they need help because this is pure sociopathy and something no one should ever even consider. They have lost it. I hope they realize the consequences of their actions are vile and reprehensible so they can get the therapy and psychiatric help they desperately need.

[@The1Herton]

​@@thechazz3230you can't stop science m8

[@_Tesseract]

We're just a bunch of neurons watching a bunch of neurons growing a bunch of neurons to play doom

[@coolchannelyt]

But can it run Doom?

[@ujvarig74]

Nice joke! 😂

[@Jakub98x]

Ever tried dmt?

[@_Tesseract]

@@Jakub98x how would I ever be able to afford that

[@ujvarig74]

@@_Tesseract I don't think it's unaffordable lol

[@garrettfreeborn3985]

Doom was all about demonic living tissue being fused to machinery, the fact that its the game you use to test all of this is simply amazing! This project is incredible and I truly believe in the near future it will be fully appreciated. Keep up the AMAZING work!!!

[@Dejawolfs]

i thought that was quake. in doom AFAIK you just straight up murder demons from hell.

[@NoxysPlace]

I thought doom was a game about a guy pissed at demons killing his pet rabbit

[@donda2111]

@@Dejawolfs He's referring to the cyberdemon, the revenant, the spider mastermind, the arachnotrons, the mancubus and the icon of sin, along with the various instances of some sections of levels having demonic meat tissue growing inside of man made structures and "infecting" them. Pretty much every doom game has multiple bio mechanical demon enemies.

[@realitynowassigned]

@@donda2111 still NOT the moral of the game

[@nick.19]

​@@realitynowassigned-🤓🤓🤓🤓

[@TheOnlyBiodude]

I made this game called life and forced millions of meat computers to play it. It was pretty epic.

[@PoliceTelephoneBox]

I'm glad that the path to manmade horrors beyond comprehension is being recorded for posterity on KZbin.

[@nesnahnevard4907]

Hello future history teachers :D

[@Virtualmassslave]

doom is the way to go

[@stiffori]

how ominous, our doom starts in doom

[@preppertrucker5736]

Sci fi horrors beyond our comprehension coming soon 💀💀💀

[@ultimatecultchaos]

Agreed.

[@joflo5950]

I've been looking forward to this project for years. But now that it's here - I think I'm even more excited for IPSs and Brain Organoids. What you're doing in this video is crazy, but I had no idea these things could be done outside an institute or pharma company. Please keep up the good work! I don't want to wait a few more years for the next one.

[@aitortilla5128]

Even if it can be done outside specialised centres the equipment needed is quite expensive so it's not reachable to everybody.

[@Yuuri066]

@@aitortilla5128 the fact that it's available to anyone at all outside of a company lab like this alone is already crazy.

[@JordanPlayz158]

​@@Yuuri066yeah, and if you can do it yourself, you can share what you learn and such (I'm sure at most of the places with the equipment, you'd need to sign NDAs)

[@Gustoberg]

​@@Yuuri066 it's mostly because it is an extremely new and unregulated field (new in we're just now getting to grow these) in some years, if shit becomes like chatgpt it'll probably have more regulations

[@charlietheuncreative6737]

I am INCREDIBLY excited for these manmade horrors beyond comprehension

[@lubricustheslippery5028]

He is going to release hell on earth

[@Lil_Harvard]

Well I can comprehend these horrors just fine, must be a skill issue 😎

[@mrjoe332]

I might even kiss them on one of their many mouths

[@sanstheblaster2626]

>man-made >beyond comprehension Pick one.

[@st.altair4936]

@@sanstheblaster2626 KZbin is man-made, yet its algorithms are not fully understood by anyone on the planet. Current LLMs like gpt 4 are also man-made, and their algorithms are not understood at all. Man-made =/= comprehensible

[@Chucky5525]

@thethoughtemporium I downloaded this video to watch on my commute and I felt compelled to come here and write a comment. Watching those fluorescent neurons gave me some sort of nostalgia I haven't experienced before, it was as if the neurons in my brain remember the time when we were single celled organisms and had to work and compete with each other for survival. Seeing those dendrites made me think of the cosmos as a whole and how galaxies tend to form these super clusters that they too are connected to each other through their own special "dendrites" of plasma and magnetic filaments. The saying "as above so below" could not be more true! The work that you are doing is akin to what alchemists in the past have tried to achieve except the philosophers stone in this context is a fully functional cyborg

[@alexchunlin5527]

I can't believe I'm just a vat of neurons trained in a lab to simulate a life where I watch neurons trained to play doom

[@robertfox4114]

Botlzmann brain-like paradox

[@venustrap3030]

Stop talking you electron stimulant I’m the one true vat of neurons

[@ninjapowerx11]

Literally mythought though 😂 tell me thats not what we are now 😂 they can attach the nuerons to a meat suit or a robot, we are biological technology, biological being what we can "natural" 😂

[@SpringySpring04]

Its interesting; I think that if the neurons that were being used as the AI to train to play DOOM were to become somehow sentient, that "brain" would, from a philosophical perspective, be able to perceive only the world of DOOM that it is connected to. Really makes simulation theory sound a lot more weird if we think of it in this type of context, lol!

[@NotVergil]

Holy crap that's a brilliant idea

[@SpringySpring04]

@@NotVergil Vergil?!!!! lol

[@icedqq]

it only really sees the variables which is a bit scarier

[@thomabow8949]

Referring to the neurons involved as a brain isn't necessarily an appropriate use of the term, though I understand what you mean.

[@SpringySpring04]

@@thomabow8949 ah my mistake, you're right. I guess I meant brain in the metaphorical sense as a collection of neurons forming one? Idk I'm not a neurologist

[@EnigmaverseElysium]

This reminds me of a thought experiment we had in philosophy, “Are we just brains in a vat?”. This video certainly puts things in a whole new perspective for me.

[@usmanfatih6436]

Imagine the rat neurons gain self-consciousness and then thinks that it is in a vat. Then some neurons agree but some disagree, and they/it will never know if it is in a computer. Really bends the definition of reality.

[@pintolerance785]

You took philosophy.

[@Boiabba]

@@pintolerance785 No u

[@IscAst4]

🥱🥱

[@stumbling]

*PLEASANT FEEDBACK SOUND*

[@sevs9550]

I'm gonna be mad if my entire existence is just a rat neuron running a simulation

[@KirbyFokson]

Now I'm thinking "what if I'm just a ball of neurons in some simulation to see how far they can push a ball or neurons?". Right back into existential crisis mode lmao

[@kpunkt98]

Love how more creators are embracing where missiles are and where they aren't.

[@MouseGoat]

?

[@ody1canobe]

@@MouseGoatthe missile knows where it is at all times. It knows this because it knows where it isnt

[@mikuenjoyerXD]

​@@ody1canobethe missile knows where it is because it knows where it isn't

[@lunarology9158]

@@mikuenjoyerXDlmao i seen that same video

[@gaiusfulmen]

@@mikuenjoyerXD By subtracting where it is from where it isn't, it can determine where it was---and where it wasn't

[@devonmcnealy8900]

This is hands down my favorite channel. I can't wait to see small brain play doom.

[@time_keeper643]

The human disregard for anything and everything natural amazes me. First me made rocks think, then we created life and placed it into the world controlled by those rocks for out own amusement. Great video and great project! I am glad I was able to experience it.

[@nithsk]

Imagine neurons being used like this at the scale of the original massive room sized computers from the 40s

[@Spheraz]

the future of ai?

[@moahammad1mohammad]

A giant cave made of living, thinking flesh

[@Spooky90097]

Search "Rain World: Iterators"

[@Redbird_]

​@@moahammad1mohammadsomeone should anolog horror of this theme

[@iosis9324]

​@@Spooky90097It's not a computer the size of a room, it's a computer the size of a city. And in my opinion, Iterators are not exactly biological.

[@lilknox2225]

Ayyy update to the neuron project, who else has been waiting for this😂😂

[@Raven3one]

ME

[@fashiharz8584]

Me! 🙋‍♀️

[@evanbarnes9984]

Literal years! So stoked

[@E-dart]

Me!!

[@josiahvalentine3430]

The fact that a possible result could be coworkers having a doom tournament with brain clones is both hilarious and insanely fascinating

[@Logos729]

And absolutely terrifying :D

[@nikotheoneshot]

my question is would these mock brains reflect their _actual_ brains at all

[@lastyhopper2792]

@@nikotheoneshot I highly doubt that. For one, these brains don't have any memories from their actual brains.

[@hae9903]

@@lastyhopper2792 But they would be genetically identical. Yes, they're only a couple thousand neurons but you could eventually make them larger. Where do you draw the line from a cluster of cells to a lab grown human without a body?

[@lastyhopper2792]

@@hae9903 Did I interpret sgtmajorkiwi's "reflect" differently from you? Anyhow, the answer to your question is I don't know. I believe the one who is responsible to find the answer to that question would be these scientists who are currently experimenting with biological brains. They have the ethical responsibility to prevent a conscious being from undergoing involuntary experiments.

[@spencerpark1459]

One thing that might be interesting to test is the effects of Psilocybin during training. In humans it supposedly allows our neurons to rewire and communicate differently leading to neuroplacisity

[@Eutropios]

5:37 Don't think you can slide that meme past me, sir. "The missile knows where it is at all times. It knows this because it knows where it isn't."

[@helenbooth5109]

By subtracting where it is from where it isn't...

[@mechanicol5685]

​@@helenbooth5109 From where it isn't to where it is.

[@miguelvelez5348]

There's a trick to increase adhesion of PDMS to glass slabs, which is to treat the glass slab with plasma. Might help with the leakage of the biological glue. Maybe even PDMS serves as a good substitute.

[@eldenjim]

Leakage of biological glue 🤤

[@snail2755]

@@eldenjim Mmmm I could go for some biological glue right now

[@tr3vk4m]

Use the Plasma Rifle. Or BFG if you need treat a large number of them at the same time.

[@0NeeN0]

​@@eldenjimSorry that I've been mean towards you in comment before, I had too much biological glue and had to drain it.

[@Justin-dv7ul]

someday these neurons will speedrun minecraft, and beat all the world records.

[@the_devolper]

I think that it would not be that more difficult than what they are doing (obviously it is incredible in general)(I do not know basically anything on the subject apart from what they explained in the video): I think they would "just" have to make the thing bigger and write some more code that would still be similar, then I think, given that the smaller version works properly, that it should be able to play Minecraft, or at least perform relatively simple tasks in the game, like mining

[@rach_66]

human brains have neurons, so that's already happening 🤓

[@TerraKnight27]

the neurons will "accidentally" install drop rate mods

[@ARACHNIDPARTY]

@@TerraKnight27waiting for the day the neurons hire a rocket scientist to “debunk” their cheating scandal

[@kh6853]

Not sure how they could beat the set seed any% TAS of 20 seconds...

[@MutekiAzy]

Great video.This is some genuine sci-fi cyborg stuff! One thing that I just don't have the willpower to stop myself pointing out though (sorry!): Reading (the place in the UK, not the act of perusing books) is pronounced "redding".

[@readmore8974]

5:41 Appreciate the reference

[@Rhuke]

Imagine playing a multiplayer game someday, and you just get destroyed by literal neurons Edit: Istg people need to understand why I said *literal neurons* and not neurons controlling a human body 💀

[@soupcangaming662]

To be fair, we are basically neurons making controlled seizures (or shocks, heh) to a hunk of meat. Ennard controlling a corpse husk makes more sense now.

[@amvora]

@@soupcangaming662just imagine how our flesh is miserable in gaming compared to naked neurones, while we have to see a threat, send a signal for our hand to contract index finger so that we shoot it, neurones basically see threats and shoot immediately

[@whos_that_one_guy]

Test tube gaming

[@wintergreen9949]

​@@amvora from the moment i understood the weakness of my flesh, it disgusted me..

[@Swingingbells]

That's literally how it already works when you're playing against your fellow humans lmao

[@JonBrownSherman]

I love science. Thank you for sharing with us all of your amazing work!

[@JonBrownSherman]

@jacktheass-yg2ek I hath doted

[@mmx2731]

This in depth video about your entire process is amazing!

[@TheLazyBot]

I demand to see more manmade horrors beyond my comprehension!

[@brawlstars_SMG]

thats called death

[@GMoth]

This is a manmade horror perfectly within comprehension, no? Sometimes, the things that can be known are worse than the unknown.

[@tachikomagaming2451]

human creation is so beautiful

[@cobgod1415]

I can comprehend this pretty easily so that's your problem I guess

[@sunnesonne]

🤓

[@DarkArachnid666]

A lot of people don't know this, but the motor units inside muscles are binary, rather than analog, in nature. That means if you are using 80% effort to perform a physical task and you have 10 motor units, 8 of them are "on" and 2 of them are "off", rather than 80% of each motor unit being "on" like you would probably assume. Not sure how this relates to neurons but I thought I'd mention it.

[@TheGershon]

So let me get this straight: you guys are gonna grow Metroid clones of yourselves out of your own skin cells, and then train them to play competitive deathmatch against each other? Finally, the future's starting to seem interesting

[@zport1853]

imagine training against a living trained clone of your cells in video games or cooping with one

[@silentwraithgaming8631]

@Blueness1230 we both know thats a lie

[@Ensensu2]

I would settle for sperm races instead of horse races.

[@gaintslash366]

I want to do this

[@bignuts3430]

If by interesting you mean fucked up then, yes, it is.

[@Cat-That-Jams]

If it’s hardware, it can run Doom. If it’s organic matter, it can _play_ Doom.

[@lookingforsomething]

What I like about this is that it's like a simplified research paper, but just made so that many people feel as if it's digestible and understandable. It helps that there are pop culture things to attach to as well (games), but I really started thinking that many research papers could be presented this way in the future if we open our minds a little (heh). Amazing work and thank you for the video!

[@funtimedavi]

I didn’t have fear of AI until I know they’re doing living brain robots.

[@bananaeclipse3324]

The AI will become organic...

[@Zoruk_]

That means we could make anime waifus irl tho

[@NicCageForPresident2024]

​​@Zoruk_ and they will destroy you just like a real wife. But worse.

[@sadrakeyhany7477]

@@NicCageForPresident2024 I don't mind as long as the AI does it looking like makima...

[@Enzo012]

But we're living brain robots already?

[@ultimateo621]

I am so hyped for the brain cell quake tournament. I cannot even begin to describe how excited I am.

[@cwkapiushon]

@duccem2774 imagine cheating with neurons instead of scripts

[@maesdejardin8648]

"But can it play Doom" That really is THE benchmark for all things

[@GhoztlyGhazt]

Holy shit real living creatures that can only see DOOM and only live in DOOM forever.

[@TheCaptNoname]

For them, DOOM is _truly_ Eternal

[@judet2992]

@@TheCaptNonameincredibly underrated

[@GhoztlyGhazt]

And if they escape, DOOM shall be on us.@@TheCaptNoname

[@wooblydooblygod3857]

Pretty sure we have no idea wether they’re conscious or not.

[@CHICKEN_sandwich_from_ohio]

DOOM IS LIFE

[@nomekop777]

The concept of a cyborg in science fiction has never, as far as I know, started with a machine and added organs to it. So this is really neat, if a little scary

[@DefaultFlame]

It has a few times, but it's very rare. For example, in the Eclipse Phase TTRPG your character can be an AI that saved up money from it's dayjob of managing social media for a megacorp and left cyberspace in an artificially made biological body it bought to walk around in the "real" world with, because it wants to LARP as a street samurai.

[@nomekop777]

@@DefaultFlame and there's Bicentennial Man

[@DefaultFlame]

@@nomekop777 True. I've also seen it mentioned in a few sci-fi stories, though I couldn't name any of them to save my life.

[@kydelvetus642]

What about the T-800 terminator? It has a skeletal form that is 100% a machine, and living tissue can be added on top of it to turn it into an infiltrator terminator

[@funnyvalentinedidnothingwrong]

​@@kydelvetus642I think the lack of meaningful connection to the machine makes it not a cyborg. It's a full machine, it's just wearing skin like a costume.

[@oasntet]

Love the "They're Made of Meat" clip. Instant classic and I love that adaptation. "But who would want to meet meat?"

[@lua_programmer]

They gotta make it into an isekai "That time I got reincarnated into a rat. Now I play DOOM for the rest of my short live"

[@nc2526]

This could be a plot for "That time i got reincarnated in a video game, but that game was doom, so I decided to live a slow life in hell".

[@MouseGoat]

yeah, guy might accidentally make doom slayer D:

[@mordet2]

Damn, sounds authentic.

[@atleast4566]

Would we call that a meatsekai? 😆

[@Electronica27]

Blended Rat: Blended Rat

[@Electronica27]

That time I was put into a blender and transported into a video game world!

[@bens1cultist405]

I do believe a “meat robot” could also be classified as a Frankensteins monster

[@ElishaFollet]

Technically it could also count as a cyborg as well.

[@cantinadudes]

True, its literally Frankensteins monster

[@official-obama]

@@cantinadudes he's named frankenstein? i never knew that.

[@mahadkalam59]

@@official-obama The creator of the monster is Frankenstein

[@Smokinjoewhite]

@@mahadkalam59 They meant the creator of this video, if this was literally Frankenstein's monster then the creator must be Frankenstein.

[@1oglop1]

I can only imagine making a daily smoothie for my new PC to play the latest games

[@bariumselenided5152]

I would gladly start feeding my pc if it meant I could play on ultra settings lol

[@СергійДємєнтєєв]

Maybe for first few years, but then, I think that a "feeding network" will be established. Sidenote: Imagine if living blocks became literal living blocks. Will their walls be out of bones?

[@mehundmeh5356]

i Image some cubes only Work with brand smoothie which are kind of expensiv 😅

[@m0rjjj666]

imagine the little shitter you need to empty after every gaming session

[@QuixoteBadger]

Like hydroponic gardening, except you are growing an aimbot.