Gut-Brain Connection in Parkinson’s Disease

Listen as Dr. Richard Manfready, Instructor in Medicine in Digestive Diseases at Rush University Medical Center, shares the gut-brain connection in Parkinson’s Disease. Dr. Manfready elaborates on his research that has him working backwards in a remarkable way. He has taken the known factors about Parkinson’s - loss of dopamine producing cells due to misfolded proteins - and has notably taken a step back from there. By finding that inflammation can cause proteins to misfold, and working backward, he’s asked the question: what causes the inflammation? Listen as he comments on what he’s finding as a reason for this disease-inducing inflammation.
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[@roryblake7311]

Thanks for the program. The Microbiome appears to build neurotransmitters involved in PD. I'm a clinical pharmacist working in moving correct neurotransmitters via enhanced lymph system function to the proper lymph nodes. Walking seems to help because the lymph system needs muscle movement to work. More is on my personal channel.

[@poweroverpd]

Thanks for listening, Rory, and dedicating your focus to helping others!

[@neilhoyt675]

Terrific/informative interview. I highly recommend it.

[@poweroverpd]

Thank you so much! Glad you enjoyed it! Be sure to check out our other interviews as well.

[@NancyBaccala]

Iiíttttttttttttttttttttttttttttttttttttttttt

[@prassu81093]

Does SERRAPEPTASE help in removable of accumulated alpha synuclein protein in Parkinson's disease?

[@susanedghill6597]

Would be nice to have answer ???

[@jonnymakers9560]

Exactly to me this is good research but absolutly NO help

[@TW-il4vy]

Something in the food - yes it's glyphosate - it chelates copper and other crucial minerals and affects beneficial microbes.

[@poweroverpd]

Thanks for sharing!

[@TW-il4vy]

@@poweroverpd Please consider inviting Dr. Stephanie Seneff at MIT for an interview for us to watcch. She has done a tremendous amount of research on glyphosate and how it affects health.

[@MnrBugi]

​@@TW-il4vyI remember her to also be one of the first to point out the Prion problem regarding covid

[@prassu81093]

Does a leaky gut lead to Parkinson's disease?

[@anniepeters8072]

Thanks 🙏 good info.

[@poweroverpd]

Glad you enjoyed it! Thanks for watching!

[@shakinglifewithkazz]

This was very interesting.

[@poweroverpd]

Thanks for sharing the feedback! Glad you found it informative! Be sure to subscribe as we have several more interviews coming soon!

[@Daissweetest]

What about penicillin, I had strep throat a every year from 5-11, stomach issues afterwards

[@poweroverpd]

Dr. Manfready encourages patients to speak with their health care providers about specific questions related to Parkinson’s and their general health.

[@RMD992-f2n]

The experts in this field don’t seem to have an interest at all in early diagnosis. The neurologist method of diagnosing by a questionnaire is a complete joke

[@larryplating8036]

What about the neurotoxin Hydrogen hexafluoride put in the drinking water by many municipalities?

[@poweroverpd]

Dr. Manfready encourages patients to speak with their health care providers about specific questions related to Parkinson’s and their general health.

[@RMD992-f2n]

Are there any tests you can do to see if there are Lewy bodies or these problematic proteins present in our gut ? Why does no one talk about testing ? None of this even matters if you can’t detect it and take action early. Incompetent doctors

[@yourcelebrant]

Dr Dale Bredesen talks aboiut the many and varied contributing factors and of couirse diet is a major one. How could it not be as we are literally made from what we eat. And as fibre is only found in plants and Zero in flesh then its also obvious a plant rich, plant exclusive diet, plant based diet is going to be a major contributor to the constipation issue and it's effect of the brain.

[@markneinast]

Once PD occurs, can gut health improvement improve the symptoms of PD?

[@poweroverpd]

Dr. Manfready encourages patients to speak with their health care providers about specific questions related to Parkinson’s and their general health.

[@jonnymakers9560]

@@poweroverpd Why? our health care provider does not know anything about his research...this is going in circles and it is so frustrating...I am tired of it

[@AI-vs7sm]

Once again, we see the case where each research entity, ( labs, university research, etc), are in their own little world, trying to find their own solutions to the study problem ! Guys, wake up, smell the coffee, and stand up to look outside of your cubicle! What you are talking about, short chain fatty acids, are called KETONES! Yeah, that's right, your study subject is being talked about everywhere in the KETO/LOW CARB WORLD! Leaky gut? Yeah, that's caused by inflammation as result of eating high carb diets. Recent changes in western diets? Yep! Excess carbs in diet. The body makes its own glucose in the liver, so, ANY CARBOHYDRATE IN THE DIET IS EXCESS, AND INFLAMMATORY! But, of course, it can't be so, because established medicine won't recognize low carb as a viable option. Cross reference your data with Reputable low carb clinics ,like Gifts Health, and see how much this all overlaps! Its not a fad diet anymore, its real science that Eminence based medicine doesn't want revealed. Just ask, WHAT HAVE YOU GOT TO LOSE???

[@AI-vs7sm]

Ah, spell checkers strikes again! Should read Virta Clinic, sorry.

[@susanedghill6597]

Does celiac disease make your chances for Parkinson’s worse ?

[@poweroverpd]

Dr. Manfready encourages patients to speak with their health care providers about specific questions related to Parkinson’s and their general health.

[@Bestvidoes3078]

Probably yes

[@jackcurvin9769]

Is there anyone attempting to develop a pre or probiotic that Target's Parkinson's?

[@poweroverpd]

We aren’t aware of one, but recommend that you talk with your Doctor to check.

[@TrishTruitt]

I believe Dr. William Davis is working with a company run by a woman focused on Parkinson't treatment with Lactobacillus reuteri and other related bacteria. "Sugar shift" maybe, by BiotiQuest?

[@TrishTruitt]

@@poweroverpd Most Drs are terribly ignorant of microbiome strategies to treat disease.

[@AI-vs7sm]

The constipation is a result of eating TOO MUCH FIBER! If your sink is clogged, does it help to dump more garbage down the sink?

[@AI-vs7sm]

Intermittent fasting low carb diet, both help fix leaking gut. If you want the short chain fatty acids, keto or low carb ,fasting!

[@TrishTruitt]

Actually there some evidence of the microbiome's influence on that. Check out an article "Probiotics Improve Nonmotor Symptoms of Parkinson's"

[@margaretlouis5418]

Llll