Hardy Weinberg Principle for the USMLE Step 1

[@polk304]

You are the first person to make sense of this and a bunch of other things in medicine. i hope soon enough you will be popular. God bless

[@physeo-USMLE]

🙌 thanks for the kind words! We're glad you're liking it!

[@pierce1234567891]

VERY CLINICALLY RELEVANT EVERY DOCTOR ALWAYS TALKS ABOUT THAT THIS IS ALL THEY DO ALL THE TIME EVERYDAY

[@ABDULRAFAY-lc7ve]

😂😂

[@drayeshaali9800]

You explained better than kaplan trust me !!!

[@mathew555s]

This was absolutely amazing. Incredible. I was half asleep while watching this and still learned the concept. Absolutely amazing. Just amazing. thank you.

[@drmohammad6429]

best explanation ive ever came across so far

[@mazifatemi2488]

Thank you so much! I have never been good with genetics and would always get questions like this wrong. Yesterday on my NBME I got TWO questions right because of THIS video

[@enmanueldejesussirisreynos9788]

Just amazing, perfect explanation, all make sense. I am even teaching using this video as base. Thanks a lot

[@vanshajchandra307]

Finally p=1 made sense to me..thank you so much

[@minenhlengcobo2761]

Thank You. Thank You. Thank You. This explanation was so simple.

[@adlesal24]

SUPERB YOU ARE ASTONISHING WHAT A GREAT SIMPE EASY EXPLANATION BETTER THAN MANY OTHER WEBSITES YOU REALLY GAVE ME GREAT IMPRESSION ABOUT YOUR WEBSITE

[@mariyaasghar7539]

To the point , well explained ! Don't have words .. great job :)

[@physeo-USMLE]

🙌

[@An-oj6ss]

The best!! Thankyou so much!!

[@sriharshakandlakunta8954]

Finally a guy wid quality on this shit

[@andrewmurphy5403]

Thank you!

[@danachavoshian1025]

Thank you so much for this video!

[@danagreenberg945]

was super simple and good thank yo u so much

[@reuvenmeirherrera9580]

Thank you for this video!: at 7:51 why is probabiltymom is a carrier 2/3? We said pro. that mom is a carrier is EITHER 1/3 OR 2/3.. right? so why did you choose 2/3 and not 1/3? Thank you!

[@bann9437]

I think cuz it’s the higher probability

[@manlikanamkaew2220]

Thank you so muchhh~👍💕

[@tariqalwafaei6304]

Thanks a lot

[@Dr.SaifAlzubaidi]

Thanks a lot. I just don't get why you multiplied 1/4 by 1/150 and 2/3... If they're asking for the probability that their child would be affected, and assuming the parents are carriers, isn't the answer 1/4 from the Punnett square?

[@gichinc4373]

Because total probability in AR diseases is the probability of both carrier parents passing down the mutant allele (1/2 X 1/2 = 1/4) X probability of mother being carrier X probability of father being carrier . If the question says both parents are carriers , then each parent has a probability of “1” . That would be 1/4 X 1X 1= 1/4 (Like you said) However this question requires us to calculate the probability of each parent being a carrier . Thus: 1/4 X 1/150 X 2/3 1/4 = the probability of each parent passing down the mutant allele (1/2 X1/2) 1/150 = probability of father being a carrier 2/3 = probability of mother being a carrier If the question said mother was a carrier , then It would be : 1/4 X 1/150 X 1 1/4 = the probability of each parent passing down the mutant allele (1/2 X1/2) 1/150 = probability of father being a carrier 1 = mother is a carrier Thus as long as the question doesn’t mention either parent being a carrier (then probability would be 1 ) , then it requires us to calculate the probability .

[@luisrosoccer]

thank you :)

[@josh6149]

How did you get .006587 from 2 x 0.9967 x (1/300)?

[@fatimaserrato6929]

yea, that's what i was trying to figure out. I kept getting .006645

[@ozziedog18]

@@fatimaserrato6929 He used .988 instead of .997, so I guess he made a mistake

[@enriqueparedes1104]

my friend , please could you explain me how did you get 1/150 for husband? thanks in advance

[@herosky6148]

2x1/300 =2/300=1/150

[@herosky6148]

let me know if this helps even though its 4 years later

[@preethi7751]

Wow! Amazing.

[@julianagarcia218]

amazing!!!!!!!

[@hayriyetufan6310]

In second question why did we eliminate that the possibility of father is ressesive homozygous? Do we have information that the father is healthy? Thank you very much :)

[@mellowdoctor9029]

Just magic

[@doctorposting]

wait what? theres no calculator on step???

[@Jboy806]

Since they are both from the same population, why is the probability of the wife being a carrier not 1/150?

[@drgunjanchaudhary5689]

Formula of becoming queen -->> princess 👸🏻 😊🙏❤️💋

[@SlaughterALABAMA]

Can you explain why in the second question the husband is 1/150, when in the first question he was 1/300?

[@nanasardarova1495]

In first question husband was carrier 2pq = 2(0.9967×1/300),he took 0.9967=approximately as 1 so 2(1×1/300) = 1/150

[@drnykterstein_]

I dont get why in the x linked condition, you took q as 1/10,000. Shouldnt it be q^2 as 1/10,000?

[@drnykterstein_]

Ohh i got it! Thanks!

[@mdilias3640]

Thank you very much. please, cover more genetic topics for USMLE!

[@sashak6798]

:') thank you

[@mellowdoctor9029]

Magic