[HAS] Examining Resiliency in Pharmaceutical Drug Supply Chains Incorporating Stakeholder Behaviors

Health Applications Society Online Seminar Series
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Speaker: Dr. Ozlem Ergun, Northeastern University
Seminar Title: Examining Resiliency in Pharmaceutical Drug Supply Chains Incorporating Stakeholder Behaviors
Date: June 28, 2024
Abstract: The growing epidemic of drug shortages in the United States causes challenges for providers all across the critical health care infrastructure and demonstrates the lack of resiliency within drug delivery supply chains. With many of these drugs having no acceptable substitute, drug shortages directly translate to a public health and safety risk. The underlying causes of shortages include a wide variety of disruptions from manufacturing suspensions due to production challenges to the physical impact of hurricanes on critical manufacturing sites and demand spikes. While some shortages have been linked to large events, this is not the case for all shortages. One of the understudied elements driving this crisis is the role of stakeholder behavior and decision-making practices across the supply chain echelons. We present an integrated simulation framework, which allows for instantiating, testing, and improving supply chains when accounting for behavioral components of the system. We examine how manufacturing disruptions in a pharmaceutical supply chain impact evolving trust dynamics among the stakeholders during and after a disruption and study the implications of these dynamics for the supply chain performance. We also develop and evaluate deep-learning based ordering and allocation decision support tools.
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