Beyond LDL-Cholesterol: These Culprits Drive Artery Plaque Build Up

[@ThriveCollective1188]

What I have come to realise having dealt with many metabolically unhealthy people is this. Attempting to explain and educate on the underlying reasons for their predicament has limited value and tends to lead to selective understanding if not thorough misunderstanding. It’s sad seeing my 75 year old mother and father taken on a ride with the latest weight loss advice after decades of believing in every changing public health advice. Best spend our energy encouraging the simplest health routine of clean water, whole foods, fresh produce, oily fish and lean cuts of meat. A daily prescription of waking up with the sun, walking outdoors for at least 30 minutes, deep breath work for stress and winding down with the moon. When people have mastered that simple lifestyle they have done the best they can and deserve to focus on enjoying connections and experiences that this human experience offers. It’s amazing what falls into place when we stop worrying and start living with a little faith that everything will work out if we stay consistently grounded in basic healthy living I do enjoy the nuts and bolts of our amazing human body. When things go wrong and we end up in hospital it’s surely a good time to catch up on the why of it all but otherwise no need to hyperfixate

[@davidhill6960]

A week of bed rest in the hospital on low protein institutional chow will take a big hit on your lean muscle mass. Substantially increase protein intake with smuggled food items surreptitiously brought to your bedside.

[@XaqNautilus]

Over sixty years of research and all they have is still only hypotheses. The best they can say is that high LDL "associates with," "is linked with" or "correlates with" based on questionable evidence. They cannot definitively say "causes." These hypotheses should have been discarded long ago.

[@offensivearch]

I doubt they could ethically induce high blood pressure or diabetes in people to be able to make causal inferences. New causal modeling approaches might be able to make causal statements using the existing experimental designs, but health science researchers are about 80 years behind where current day statistical modeling is at today.

[@genegayda3042]

From the channel, Low Carb Down Under, I've hear of a new theory, Oxidated Linoleic Acid theory of heart disease. One omega 6 fatty acid, linoleic acid, is up to 50% of vegetable oils (butter and meat have about 3-5% linoleic acid). The body cannot burn up linoleic acid for energy, so it collects in cells. It is very easy to oxidize this fatty acid. As it collects in cells, it also collects in the shells of LDL cholesterol particles. It has a high rate of oxidation and damages the LDL in conjunction with high blood sugar. In their lecture, Low Carb Down Under shows a chart of sugar intake, seed oil intake, and death by heart attack over the past century. The rate of heart attack death correlates pretty well with seed oil consumption. Sugar consumption increase earlier and faster than seed oil and heart attack rate

[@XaqNautilus]

@@offensivearch Even if getting actual causal data is unethical, they are drawing conclusions on "associations" using bad data. Nutritional surveys usually are fairly short questionnaires asking people what they ate over the last month, few months, year or possibly years. People don't remember what they had for breakfast yesterday morning. And people especially in the media cite these studies as strong evidence when that is simply not the case. Nutritional epidemiology could be done so much better than it has been done. Study participants could record what they eat using apps and actual strong associations could be better correlated. The bigger problem actually comes from studies are being done to sell product rather than actually learn something they don't already know.

[@KrummyProductions]

I would bet the basic understanding was discovered a long time ago, and now the propa-Ganda machine is running wide open for profits.

[@darkhorseman8263]

There are interests running interference. Luckily, meta analysis can expose publication bias, which helps identify the corrupt ones. Like they did with serotonin reuptake inhibitors and amyloid beta links to alzheimers. All based on no evidence, meta analysis shows us.

[@Sophiascott12]

There is so much useless reasearches and so many lies, If I didnt read The 21 Former Doctor Secrets by Rachel Morgan, I would be still believing in tons of nonsense from modern health industry

[@newyorkguy158]

Unfortunately, the world is populated with science deniers, their followers and people who are ignorant of science. The science deniers are the most dangerous. Be careful who you follow. This video started out well, but half way through, the misinformation started, dangerously so. He just doesn't know the science behind the causes of heart disease and the result is really dangerous recommendations.Yes, high LDL cholesterol over a long period of time is very dangerous. The body makes enough cholesterol for its needs. LDL cholesterol doesn't cause heart disease itself. It doesn't mix with the blood. ApoB lipoproteins are particles that are necessary to transport cholesterol in the blood. When the number of these particles rises to a level above the physiological needs of the body, they can pass through the artery wall in a process known as transcytosis. If some of these particles are retained inside the artery wall they start to get oxidized. This leads to inflammation, an immune system response. The ApoB particles inside the artery wall are like a foreign substance. They don't belong there. The immune system sends macrophages to destroy those particles. Foam cells form leading to the creation of plaque. This is the origin of heart disease. There doesn't even have to be pre-existing inflammation as some YT doctors claim for this process to occur. Anything that damages the lining of the artery will accelerate this process, like smoking, high blood pressure and insulin resistance. Diets high in saturated fats and refined carbs lead to LDL cholesterol synthesis. The higher levels of LDL cholesterol cause the body to produce more ApoB lipoprotein particles to transport it. That is why a diet high in saturated fats is so harmful. Animal fat in the diet should be limited. The best diet is one that emphasizes vegetables, legumes like beans and lentils and I would say omega-3 fish like herring, sardines and wild salmon. I think some low saturated fat dairy like unsweetened yoghurt and kefir is good. Some fruit too, especially low carb berries. Each individual can fine tune their diet according to the condition of their health, but the basic principle is to limit saturated fat. Also, a person with high LDL-C should definitely consider taking a statin. They do prevent heart attacks and strokes and they offer a way to reduce ApoB quickly.

[@ShoppingEmail-dr1fs]

the new way of promoting books is to infiltrate KZbin comments. she talks about the benefits of intermittent fasting, there are none - aside from calorie control. autophagy happens when you sleep, when you are in a calorie deficit and when you exercise and naturally when you do nothing. In fact fasting itself can help some cancers grow. but as for the rest of it, sleep, eat fibre, etc, we know this already.

[@DK-pr9ny]

Seems like LDL is more of a firefighter than an arsonist.

[@darkpatches]

Firefighters don't stick around (literally) after putting out the fire. Not an apt metaphor.

[@DK-pr9ny]

@@darkpatches if there’s still a fire, they do..

[@KrummyProductions]

@@DK-pr9nyhaha nice

[@Martihorn]

Exactly! My cardiologist, Dr. Nadir Ali coined that term. He is exposing the ridiculous notion that LDL causes heart disease. Also Dr. Bart Kay is a great resource in KZbin.

[@WasenshiDo]

Yup

[@michaelferguson9679]

There is no difference between the cholesterol in LDL, VLDL, and/or HDL. Cholesterol is not the problem. The difference is in the packaging (proteins). The medical community doesn't have a drug to directly address/treat the APOB, so they promote the fallacy that cholesterol is the problem. Every cell in our body needs cholesterol.

[@nerolowell2320]

What is APOB?

[@Sk1pperCS]

@@nerolowell2320fats are not water soluable, so they need a packaging that will be soluable since the blood is mostly water. APOB is a lipoprotein (part fat part protien) that transports cholesterol from the liver to peripheral tissues. This protien bit “apob” is on the outside and is hydrophilic, while the fat(cholesterol) is on the inside and is hydrophobic. Thus allowing fats to be transported thru blood! Fat or anything that is hydrophobic will not be moved anywhere in the body without these carrier proteins (in 99% of cases)

[@nerolowell2320]

@@Sk1pperCS 👍

[@newscienceofphysicalhealth2934]

Thanks Doctor..we should listen to you..oh wait..where was your PhD in medicine, lipids and cardiology from?

[@tomjones2348]

Bingo.

[@leemanwrong]

Atherosclerosis is only found in the bends and bifurcations of the arteries, what these areas have in common is high pressure and turbulence.

[@arnoldfrackenmeyer8157]

BINGO! Pressure and Turbulence! This was also my conclusion. It took a swimming pool to finally convince me. Holding my hand over a high pressure circulation jet closest to the pump for an extended period of time, my hand started to hurt. Meanwhile the weak jet farthest from the pump didn't hurt my skin at all.

[@auldlangsign3179]

@@arnoldfrackenmeyer8157 Built in obsolescense to make sure we leave room for the next generation? Modern manufacturers of goods realise that well-made, long-lasting goods as per Victorian engineering was a negative rather than a positive.

[@Sk1pperCS]

Interesting. I was watching a debate between Paul saladino and dr Twyman (don’t remember his name) but he was a cardiologist in the field. He said the opposite. Who do i believe lol

[@leemanwrong]

@@Sk1pperCS You go listen to Bart Kay who is a cardio pathophysiololgist, a specialist in heart disease who used to teach cardiologists.

[@nicolewalker5502]

See Bart Kay. No arterial disease in the venous side!

[@Silverbacked_Gorilla]

That is one of the best summaries about LDL I have ever heard. Keep up the great content. Important work. My cardiologist, bless his little cotton socks, knows nothing about any of the data you ran through and need a smack in the back of the head to wake up. I am a heart attack survivor twice over and cleaned up my act and got off Statins after a severe reaction with my muscles, ligaments and brain fog. I know you said older subject could have memory loss, and my pharmacist said the same. But I am only 53, so that blood/brain barrier did not stop Statins negatively affecting my brain function. Now that my synapsis is working, I think most on Statins would not know how much they were being affected till they got off it.

[@CatherineHurley-wk8ef]

My husband had your symptoms. He's now on Coenzym Q10 and Armolipid - no more statin myalgia, and lower LDL scores than he ever achieved while on a statin! (We live in Europe; I don't know if Armolipid (a "dietary supplement" containing red rice, folic acid, Coenzym Q10 and Astaxanthin - the red dye from sea krill) is available in the USA. We get ours from Amazon....

[@georgeharvey7300]

I'd like to tell you a bit about my own health and a rather surprising bit of it. I have always been overweight, right now, at 78 and 5'8" tall, I weigh about 235 pounds. I smoked from about 14 to 28, then I quit. I have high blood pressure and am type 2 diabetic. I walk a lot, but never as part of a health plan. On the other hand, after had my tonsils out at five, I went 70 years without spending a night in a hospital. That ended when I had to have my gall bladder out at 75. (The doctor said it was "narley.") Last year, I had a heart valve replaced. In preparation for that,, I had to have my heart imaged with a dye that was released in a coronary artery. There might have been six people in the room where this happened. After that was done, it seemed like all of them commented on the condition of my arteries. The first one asked me, "Who are you, the expert on clean living?" Another said my heart looked better than anyone over 45 they had seen. One person showed me a replay of the images, saying, "Look at this - there isn't any plaque." Finally, the doctor asked me, "How do you keep your heart so clean?" It took me a week to figure that out. Finally, I realized that 15 years ago, I decided that since I would be eating alone and cooking for myself, I would be cooking a lot on the stovetop. That being the case, I decided to search the web to find out what the best oil is for sauteing. The result is that I have been using sesame oil for everything except salads, for which I use olive oil. Going back to the web, I found much of the same material I had seen before, which says that sesame oil can reduce plaque. I had used it almost exclusively for 15 years.

[@patriciafisher1170]

Thankyou for this. I have the family cholesterol that does not go down when you use the general diet they tell you to for high cholesterol. I have researched into it and found the studies they did on this type of cholesterol found that families that had it lived longer had fewer infections and there were other benefits I can’t remember at the moment. I am 75 have always been thin and very active still very active I then began getting high blood pressure. After looking into this I was able to bring it down and stabilise it by 1 walking everyday but also by taking Berberine extract and Taurine. Drs tell me every time I see them I will drop dead because I refuse to go on statins. I have always been careful with my diet never smoked or drank alcohol and now I am allergic to meat and poultry and rice and eggs. I love butter and eat that and also take coconut oil to keep my brain healthy. I am rarely sick still thin and help my daughter look after her five kids Drs cannot accept I will not take medication when I last went to the Dr and she asked if I need some medication for BP I said that I have brought it down by the Berberine she was very annoyed at me. Didn’t take my BP didn’t check me in any way I was in there to get a health check to keep my licence which you have to doin Australian when you get to 75. Told me again that I will drop dead and told me to go. My attitude is that I have had a good life no health issues and if I drop dead at my age I am very lucky. Strange you said about you using sesame oil because my kids were allergic to milk when kids I used sesame seeds and oil all the time because it had calcium in it. I will start using it again so pleased you told me that

[@harrymagooslum5770]

Thank you for that insightful information. I likely won’t forget your experience while on my ongoing quest to “hack” my health and that of others who care to listen. Your words are valuable and the time that you took to respond with them will help us all. ❤

[@beenflying1]

Triglycerides HDL ratio is the most important thing. Once I got this under control, all my health issues improved dramatically...

[@isaaccruel3994]

What if my LDL is very high(196) but my tri-HDL is very good (0.78)

[@DileepB]

I agree.

[@nancysmith-baker1813]

May I ask how you did this thankyou .

[@beenflying1]

@@nancysmith-baker1813 By cutting out sugar, pasta, rice, bread, flour and seed oils.

[@nancysmith-baker1813]

@@beenflying1 gotta it thankyou . Dose that include fruit ? Probably .

[@carnicavegirl7214]

My total cholesterol is around 250 and my triglycerides are exactly at 50, and my doctor told me I needed to go on a statin.... I walk over 10,000 steps a day, weight train, I am 80% carnivore 20% keto... There's literally nothing else I can do

[@colinfahidi9983]

Yeah there is. refuse the statin. Nothing wrong with your cholesterol or yyour triglycerides.

[@CatherineHurley-wk8ef]

@@colinfahidi9983 I'm a lean mass hyper-responder doing a very low-carb diet. I also have genetic high cholesterol. Very low triglycerides and one of the lowest CRP scores around. My doc has finally, after 12 years, put me on a very low-dose statin. I hate it, but for the first time, my LDLs are within high-normal range, while my HDLs remain high. I don't have metabolic syndrome, but medical association guidelines have to be observed. Dr Paul Mason (Low Carb Down Under) reports that no clinical studies on statins are longer than 2 years; this is because after that, results are negative, calcium scores get higher, and in fact, it is the statin that kicks off atherosclerosis. Brave New World, eh?

[@genomedia44]

Nothing else? Get another doc

[@Cmvinyl0102]

Change to fish and seafood , cut down some animal protein and replace it with vegan protein and carbs at the end of meal

[@carnicavegirl7214]

@@Cmvinyl0102 oh no....that made me so sick..I tried for 6 months 😭 I'm still trying to heal from that..

[@mbrochh82]

Here's a ChatGPT summary: - The LDL cumulative exposure hypothesis suggests that minimizing lifetime exposure to LDL cholesterol can reduce the risk of atherosclerosis and related conditions. - LDL cholesterol oxidation and infiltration into vascular endothelial tissue can lead to the formation of atherosclerotic plaque, which can cause strokes, heart attacks, and sudden cardiac death. - Clinical conditions that exacerbate LDL's harmful effects include increased blood pressure, insulin resistance and diabetes, smoking and vaping, obesity, increased blood viscosity, and sedentary lifestyle. - High levels of triglycerides and insulin resistance are indicators of metabolic syndrome, which can worsen the effects of high LDL cholesterol. - Lifestyle changes such as a low-carb diet, regular exercise, and avoiding highly oxidizable polyunsaturated fatty acids can help manage LDL levels and improve overall health. - Statins can reduce LDL cholesterol but may have side effects like insulin resistance, reduced coenzyme Q10 levels, and muscle issues. - There is conflicting evidence about the role of LDL cholesterol in heart disease, with some studies suggesting that higher LDL levels may be associated with increased longevity. - The relationship between LDL cholesterol and heart disease is complex and influenced by various factors, including diet, metabolic health, and genetic predispositions. - Main message: The role of LDL cholesterol in heart disease is nuanced and influenced by multiple factors, including lifestyle and metabolic health, suggesting that a one-size-fits-all approach may not be effective.

[@Unique_Monk]

who told it to say that ? the same people that want us to stop eating meat and eat cereal ?

[@mbrochh82]

@@Unique_Monk calm down. it just summarized the content of the video.

[@Unique_Monk]

@@mbrochh82 I’m not uncalm 🙈

[@MrBilartur]

Great job , you are my favorite and more reliable source of information and inspiration! Thanks and greetings from France 🇫🇷

[@nobukazumikami5466]

Because US foods are packed with added-sugar, we are building up Type B LDL from our childhood years. Even if you lower meat intake, your Type B LDL does not go down if you intake excessive sugar. Minimize added-sugar intake. Avoid Starbucks Frappuccino, drink black coffee, instead, for example.

[@JohnnyRocketone]

Meat does not cause disease.

[@nerolowell2320]

It is way more than what you just mention but yes cholesterol is not the problem

[@elcid4593]

What about just coffee and cream no sugar?

[@nerolowell2320]

@@elcid4593 its very fine as long as its real milk cream

[@bunchie1966]

Oh, dear. LDL is not cholesterol. It's a vehicle for carrying cholesterol to where it's needed. It is not linked to heart disease at all.

[@Smitness]

There are so many people on these platforms with no rudimentary biochemistry knowledge. Yikes

[@porkpie2884]

@@Smitness True, and they should learn from @bunchie1966

[@LarryBanyash]

Sorry, Dr Alo’s work, a double board certified cardiologist has clearly shown with literally hundreds of rct’s ( gold standard) that ldl is indeed causal in atherogenesis-nuances aside. Ie, easy look: very low or no ldl-no ascvd, period. Larry W Banyash MD

[@porkpie2884]

@@LarryBanyash I've never heard so much nonsense. Alo is a clown who doesn't know what he's talking about. He even once stated we can live without ApoB. Yet we'd die with no ApoB. Firstly: There's no such thing as RCTs in Humans. Secondly: Neither Cholesterol nor LDL-ApoB are causal of disease. If they were we'd be able to describe the physiological pathway of this alleged causation, yet NO ONE can. "very low or no ldl-no ascvd, period." Whoever said that is also a clown. We'd die with no LDL, and artificially lowering LDL or cholesterol increases risk of heart disease. Whoever Larry W Banyash MD is, he doesn't know what he's talking about either.

[@porkpie2884]

@@LarryBanyash I've never heard so much nonsense. Alo is a clown who doesn't know what he's talking about. He even once stated we can live without ApoB. Yet we'd die with no ApoB. Firstly: There's no such thing as RCTs in Humans. Secondly: Neither Cholesterol nor LDL-ApoB are causal of disease. If they were we'd be able to describe the physiological pathway of this alleged causation, yet NO ONE can. "very low or no ldl-no ascvd, period." Whoever said that is also a clown. We'd die with no LDL, and artificially lowering LDL or cholesterol increases risk of heart disease. Whoever Larry W Banyash MD is, he doesn't know what he's talking about either.

[@nelsontang1055]

well said Mike! Nuance conversation, there are several factors involved, not simply just the LDL findings which some might conclude the only reason for heart disease . good vid..

[@brianwnc8168]

Most people are low on potassium and low potassium radically increases blood pressure and blood viscosity. Mike, this is really important for people over age 40 regarding boosting potassium levels, as long as you have healthy kidneys

[@swamphawk6227]

Gotta drink that snake juice

[@zephirinedrouhin3735]

@@brianwnc8168 does potassium hurt the kidneys?

[@unou12die]

​@@zephirinedrouhin3735 the body needs a specific ratio of sodium to potassium it's 1 part sodium 2 parts potassium. 2300 milligrams sodium 4700 milligrams potassium is DAILY recommended. Depending on your activity(if you sweat a lot increase sodium a bit) if your just a small person you will obviously need less. But to be clear you can have a toxic level of anything even potassium. Too much water causes water toxicity. Good luck

[@beezowdoodoozoppitybopbopb9488]

​@@swamphawk6227 i wouldnt copy coles latest stuff though.

[@Marco-pf3te]

Where do you get your potassium from? A supplement of some food sources?

[@peggidoug]

Arthur Agaston now Supports the newer use of CCTA over the CAC - both show arteriosclerosis but CCTA shows how much plaque you're building, how much is fibrous, and how much has already calcified (which he agrees is less harmful). Recommend watching one of the Cleerly webinars in which Agaston discusses different patient cases - he doesn't just look at LDL and he doesn't just throw statins at them.

[@philiprollins3211]

Missing the essential ingredient of the issue. Which of the two types of LDL cause this problem. Large buoyant LDL are neutral to Cardio vascular. It is the small dense LDL which cause the atherosclerosis. Avoid all sugar and sources of sugar (carbs) and high LDL is not a problem. More important to watch triglycerides/hdl ratio.

[@jerrycash5606]

So, how do we get this into the corrupt doctors office?

[@newscienceofphysicalhealth2934]

My doctor isn’t corrupt. Perhaps you need a new doctor…or better still… take your evidence for corruption to a lawyer and have the doctor charged in a court of law where opinions don’t matter..evidence does…what’s that? No evidence

[@paulasusan63]

I would like an answer to this!

[@CircumambulationMaedia]

Low LDL is correlated with worse outcomes. Im carnivore and dont give af about my "higher" LDL when my HDL is high and my triglycerides are 0.x

[@someguy95376]

totally clueless response , do a little research and try to understand the facts.

[@Winterascent]

@@someguy95376 Vegans just can't help themselves trolling Carnivores.

[@colinfahidi9983]

@@someguy95376 They're 100% correct though. You're the one that's clueless

[@venicebeachsurfer]

IF that is true, then why take a statin which LOWERS LDL?

[@dennisward43]

@@venicebeachsurfer Anyone who understood science from their own research rather than parroting what they have been told to think by authority figures would soon find them thinking a totally different way. Statins do lower LDL but that does not mean it reduces your risk of atherosclerosis. It does mean it risks getting side effects from taking them. "Optimal cholesterol levels don't always translate to perfect heart health, based on a recent study that found half of healthy patients with normal cholesterol levels have dangerous plaque build-up in their arteries." It is also a fact that low cholesterol is dangerous as cholesterol is needed in every cell of your body. There is a theory that 'normal' evolutionary cholesterol levels are much higher than the guidelines and are only set much lower because most people now eat a much higher plant diet than they did prior to 12,000 years ago when the growth of agriculture began.

[@LAMETEOQUEVIENE]

another thing I forgot: Plaques DO NOT begin early in life. What we see in those called "Fatty streaks" are not made of fat (lipid) at all. They are made of white blood cells and NEVER evolutionate into an atherosclerotic plaqe. They have a different origine. We finde those "fatty streaks" even in fetus an newborns, whose cholestero levels are so lo. Their presence have nothing to do with cholesterol or with lipids. Again "The Clot Thickens" by Malcolm Kendrick, will provide you of all the PubMed references. Keep the good work!

[@terrydummitt]

Love the channel. Great video, what important information… thanks so much you’re doing a great job!

[@Ed-qn7vx]

Who paid for this study, who who published it? How was the study/ research done, how many patients, how long was the study

[@MartaD-p8d]

Thank you! I feel like a science experiment. Low triglycerides, high HDL and very high LDL. I’ve had an awful diet for most of the past 50 years, so I’m confused, but you helped me understand some things. I’ve got to get off the seed oils!

[@BrianPremo]

I’m in the same boat. I believe we qualify as low mass hyper responders. I’m very physically active. Diet is always a work in progress but even with high LDL I have never felt better. I used to have a constant rotation of health issues. Since going (mostly) low carb , high protein high fat - my doctor visits have dwindled to just yearly checkups.

[@DileepB]

25 years of 25 mg of simvastatin damaged by liver and drove my liver enzymes up. Now with low carb diet my LDL-C is at 112 after taking 5 mg of Rosuvastatin and i200 mg Berberine for 2 months, down from 177. Micro dosing and a supplement has worked for me. I hear that red yeast rice is good too. Too many doctors over prescribe statins.

[@dougehouser5672]

Red yeast supplement is a statin, fyi.

[@rodica69]

Red yeast did absolutely nothing for me.

[@CatherineHurley-wk8ef]

@DileepB - It is a comfort to read your comment. My doc. put me on 5 mg of Rosuvastatin 3 months ago; he'd tolerated my high LDL/HDL for 12 years (with very low triglycerides/CRP). But now I'm 70, and that "number" means getting a statin, according to medical guidelines. Happy to read that 5 mg is considered a micro dose; got my result yesterday - my LDL is within normal range for the first time ever!

[@webbangel2054]

@DileepB Do you take the 5mg every day of the week or just 2 or 3 days a week?

[@DileepB]

@@webbangel2054 every day. May adjust after bloodwork next week. Also take CoQ10.

[@egec1]

Thank you for this. I have high LDL and normal triglycerides. Low to normal blood pressure.

[@rickzalewski2728]

My LDL is 8 mmol/L, and 10.6 total. My great grandparents lived to 103 and 104. I wish I knew what their LDL was.

[@hjrosas071]

Probably very high. Mine is 231, which is "horrendous" according to my doctor. He says I won't make it to 50. He also says that my 101/57 BP and my triglycerides(54) are completely irrelevant. I'm hopeful that unless there's some accident, I'll live to 90 like my grandfather whose LDL was always above 200.

[@rickzalewski2728]

@@hjrosas071 I'm sure it was high also. They lived in Belarus where lard, meat, pickled vegetables and vodka was the staple diet. I was told their vaccine was intentional bee stings which they had. Simple, but not easy life.

[@janetgies8698]

@@hjrosas071My LDL is 307. I have very low Triglycerides and high HDL. My Doctor must request a LDL test for the 2 LDLS - fluffy good and small invasive particles if she wants my respect. I told her I’m not taking harmful Statins ever. 🎉. Janet

[@davidherr6793]

Yeah but they didn't live in this shitty world.

[@wigdaddy72]

@@hjrosas071mine was 162 which my doctor thought was terrible even though my Triglycerides and HDL was really good

[@Roberto-cg2gr]

LDL is only an indicator. Low dense LDL happens when you are insulin resistant.LMHR is clear high LDL does not cause atherosclerosis if you are healthy and insulin sensitive. Root cause analysis using 5 whys and fish bone analysis will point out to metabolic health

[@wbltrack07]

cant wait to watch the spin from Attia in a few years when he does a 180 on LDL

[@patricia753]

I've had much musculoskeletal undiagnosed pain. I heard of the carnivore diet which is supposed to decrease pain as it lowers inflammation. This material that you talked on regarding cholesterol and LDL, insulin resistance, cardiovascular disease, is exactly what all the carnivore doctors speak of. Compelling stuff!! Thank you

[@rsdaarud]

Try a seed oil free diet for 3 months (the Hateful Eight, Dark Calories) These suckers are very inflammatory and penetrate the endothelium, initiating atherogenesis. Cholesterol works as natures band-aid to start repair. They are associative but not causitive.

[@DavidSmith-in5if]

This is such an amazing channel! So much really important information.

[@rkingslandjr83]

41m. Started keto back in October 1923 I was 207 pounds I’m 5’6’’. I started carnivore in March. In May, I started to not feel so well and wasn’t sleeping. Got my blood work done the end of May and my cholesterol total was 461. My LBL was 371 and my ferritin level was 470. I never had any metabolic issues prior, starting to be concerned that I have done some serious damage. In May I went back to keto style diet with 30 g of carbs per day and in June I went up to 50 g of carbs per day. I am now I’m at 70 g carbs per day looking to go up to 120 at some point. I am currently focusing on fiber and my blood pressure which had seem to be all over the place, but I think it’s because I was taking too much sodium and not in ketosis. Needless to say I’m a little freaked out. Currently at 174lbs. Getting follow up blood work in Aug to see if the cholesterol comes down. I have been lifting and trying to eat properly for years. Oh and my testosterone was 248. 😑

[@krisvette5874]

I agree with general thesis that keeping LDL low is more favourable for CVD outcomes. However the elephants in the room are the subgroups; 1. patients with low LDL and plaque burden 2. patients with high LDL, poor lifestyles and zero plaque burden 3. healthy, fit people and athletes without FH and high plaque burden.

[@raff23able]

I am fit and healthy I did drink alcohol and I smoked cannabis but not tobacco. I think the smoking was obviously extremely bad I had borderline high ldl and Trigs. I ended up with significant blockages in my LAD. I ate a healthy diet and was a runner and surfer. Many of my friends smoked a lot drank a lot eat badly and have no heart disease. There’s certainly a genetic factor as my dad had a bypass in his 50s my dad’s mum died in her 50s from heart attack. I now eat a very clean diet I don’t use cannabis I don’t drink alcohol and I take a statin.

[@manyblessings917]

​@@raff23ablehave you checked your numbers since changing your lifestyle? Has there been positive change?

[@raff23able]

@@manyblessings917 yes very positive change, I have low trig, good hdl and low ldl, I have fairly good Apob, could be better but not high at all medium range. I have lowered my BP from 135/85 to 120/75. I managed to reduced my statin by half as the cardiologist was happy with my numbers. I could definitely do better by reducing more sugar and I’m not at all eating a lot at all, and I could reduce carbs. I’m 6’3 I was 13 1/2 stone I’m now 11 1/2 trying not to lose weight is now an issue.

[@porkpie2884]

FALSE. Low LDL is in keeping with WORSE outcomes

[@manyblessings917]

@@raff23able thank you for your reply. I wish you the best!

[@susancrabtree5314]

I have familial hypercholesterolemia but my LDL has yet to go over 160. Yet, my PCP prescribed a statin. My heart and carotid arteries have zero plaque, my BMI is 20, I have rarely eaten junk food, etc. Nothing I've said to him pointing out that a moderately high LDL in my case is normal and expected. I saw a cardiologist who agreed that I probably would not benefit from a statin regardless of dosage. It's frustrating to not be able to find a better PCP. FWIW, my PCP also prescribed a SSRI because of my "demographic", meaning elderly and female. Yes, he said that.

[@nancysmith-baker1813]

You should interview Dr Ford Brewer . He has a channel really good and he is the example . They Him and other docs go into this really well . I would love to have you interview him .thankyou for all you do .

[@82KW82]

LDL is not the problem.

[@Reachland02]

My doctor said high LDL isn’t a big deal unless it passes 200. Currently my LDL is 168 which concerns me but I don’t even have any symptoms from it and he doesn’t take it seriously. He told me to just do keto diet, fast, cut out carbs and sugars and exercise more and told me that I don’t need any med yet since I’m under 50 and my LDL doesn’t pass 200. He said the problem is high Triglycerides which can affect my heart. Currently my Triglycerides is around 40 but only my LDL is somehow high.

[@billmahko5688]

Matt you're awesome. Thank you.

[@Unique_Monk]

190 LDL isn't the issue - 178 triglycerides is the issue - 100%

[@rochellet7303]

Wow - your followers are growing! I'm so happy to see it. You are good for humans! Thank you for being there and putting out such helpful information!

[@sportysbusiness]

Read "the clot thickens'. Brilliant book explains it all in layman's terms. With the science, that was known years ago but conveniently ignored. Spoiler, it's not LDL!!!

[@JoeS97756]

LOL you got conned.

[@truthsayerq7264]

​@@JoeS97756 Explain the reason for your puerile little snide? And then enlighten everyone on the true cause of heart disease!

[@CatherineHurley-wk8ef]

@@truthsayerq7264 No need, here's the goods: pubmed.ncbi.nlm.nih.gov/22959954/ (Lowering Dietary Linoleic Acid) and kzbin.info/www/bejne/rXqmpZeLqqqMkLs

[@asinheaven]

Rhabdomyolysis is a very real, very serious outcome from statin use. My husband developed it after long-term statin use. I found him unconscious one day out of the blue. He spent five days in critical care, and was diagnosed with Rhabdomyolysis related to Crestor, and diabetes. He has been able to reverse the diabetes through exercise and diet, but the Rhabdomyolysis muscle deterioration continues. He is in increasing pain and discomfort after six years off statins.

[@zaminhussain2112]

I have some health issues. Reactive arthritis and anxiety. However, since last year I have lost 20 kg of body weight mainly because of lifestyle changes: from 79 kg to 58 kg. My BP is normally around 109/68 and resting pulse rate below 60. My HDL: 66 LDL: 162 Triglycerides: 69 My total cholesterol: 231 Non HDL cholesterol: 165 I do moderate body weight exercises and some cycling two to three sessions per week. The doctors suggested cholesterol lowering medication which I am hesitant to take. Apart from my crushing anxiety, I feel great otherwise

[@51249ca]

had high Cholesterol and ended up with a 90% blockage in my RCA. Super mild exertion felt like being punched in the chest by Mike Tyson or your heart being wrung out like a wet towel. Had to get a 35mm stent put in or I would not be still alive. Healthy BMI, don't smoke, don't do drugs, mountain bike regularly. I call B.S. regarding high cholesterol being "better" for you. oh, and slightly higher blood pressure readings too

[@stan8926]

Meat, butter, eggs, fish, veggies, evoo. High TC LDL, low TG. 10 years later high BP. Doctor said new data says no problem, high BP genetic pills for life. Went to WFPB and SOS free, 18 months later off pills and BP 105 70. Track your BP and if more than 110 70 take steps to correct.

[@mollybpwebb7075]

Thanks for this valuable information.

[@tonyabrinkhoff659]

Very good as usual

[@genarodiaz699]

First of all, thank you for your work. I have not studied medicine nor am I a scientist, but I read and try to understand the wise doctors, biologists and geniuses that I have met on KZbin; conclusions that my brain can reach: -1) non-debatable: studies with follow-up of the health of thousands, and millions, of people for several years have made it clear that the total cholesterol values ​​among people who live longer are between 190 and 250. -2) debatable: cholesterol does not start atherosclerosis, it needs damage to the artery to try to infiltrate it, (it does not stick to its inner layer because if this were so it would also do so in the areas of the arteries that have less blood flow, where it would be easier to stick, or in the veins, where it does not stick either; there must be previous damage to the artery that allows it to infiltrate). -3) debatable: cholesterol tries to repair damaged arteries and for some reason part of it gets stuck there, I don't know if it's to keep trying to repair the problem or because it has oxidized and can't get out of there -4) debatable: HDL cholesterol has to have values ​​between 50 and 80 and triglycerides a value of 100 or less. The triglycerides / HDL ratio should not exceed 2 I hope I haven't written many things wrong... hahaha; but I'm sure there are people with more knowledge who can tell me where I'm wrong. p.s.: values ​​in measurements of Spain, Europe

[@Mrdsmith500]

The size of the LDL particle matters. Use the Triglyceride to LDL ratio. TG/LDL = x. The smaller the number, the larger, fluffier the LDL particle size. Small, dense LDL is more problematic. If you had a number like 7, you need get that under control. However, this is only one factor in CAD risk.

[@main___name___main___name]

The medical-industrial complex will do whatever it takes to ensure its financial health.

[@jimmystewart7954]

I had my annual stress test yesterday with my cardiologist. My LDL is 192 and he wants to prescribe either Repatha or Leqvio. The side effects of both of these is not good. One being high blood sugar (diabetes). Yes, those are the words in possible side effects. I have been very strict carnivore for three and a half months, down 26 lbs and I feel ten years younger. I am 69 years old. While all of my numbers have improved he still wants me on something. I have refused the statins prescribed as well. I hope I am making the right decisions.

[@CatherineHurley-wk8ef]

You may be a lean-mass hyper-responder. Dietary carbohydrate restriction leading to raised LDL and HDL cholesterol levels. It's evidently an indicator of fat adaptation - signs that you're doing your LCHF diet successfully. Medicine is only just recognizing this, and treatment guidelines enforced by national medical associations upon their doctors means their hands are tied, or their licenses are revoked... here's a link to a study, if it helps: pubmed.ncbi.nlm.nih.gov/22959954/

[@derrellbabb]

Great content!

[@andynater1885]

In my opinion the best thing you can do for your arterial health is natural vitamin C, endothelial function is the key folks.

[@Alan_Clark]

Vitamin C is an anti-oxidant, so it could well help arterial health, but there are other anti-oxidants, such as vitamin E and many phytochemicals in coloured fruit and veg, so it is probably a good idea to get plenty of these as well.

[@markr5440]

I can’t listen to this rapid fire lesson , insane

[@GeneTakae]

You can actually slow down thé playback speed.

[@JonChat777]

Thanks for sharing these insights

[@richarddinnie1538]

Why is he (or the authors of the study) linking all these known risk factors (absolutely nothing new here) to LDL in order to conclude the risk factor “causes the LDL to cause the damage”. What on earth has high LDL got to do with it. Diabetes, increased blood pressure, smoking are risk factors independent of LDL, for goodness sake. It’s amazing. If you want to understand this, please, please, please read Malcolm Kendrick’s excellent book “The Clot Thickens”. Extremely well documents the science which shows what is really going on. Warning, pharmaceuticals companies don’t like this book!!!

[@edgadalinski7493]

I love your insight!

[@LAMETEOQUEVIENE]

Hello Mike, great background for your videos, I like it a lot. One concept: LDL particles DO NOT get "trapped" in the artery wall and DO NOT CAUSE atherosclesosis. The only LDL that we find in the plaques is de LDL corresponding to Lipoprotein (a), whose role in heart disease works by its thrombogenic role. It inhibits the conversion of plasminogen to plasmin and thus, it blocks fibrinolysis. It is a thrombogenic proccess. If you read "THE CLOT THICKENS", written by Dr. Malcolm Kendrick you will see the real cause of atherosclesotic plaques. It was never LDL cholesterol. Thanks for your work, I like it a lot! Jorge García-Dihinx MD/PhD Division of Pediatrics. Children Obesity Out Patient Clinic. Hospital San Jorge. Huesca. Spain

[@beepbeepnj2658]

"Remarkably, one-quarter of the centenarians had high Lp(a) serum levels even though they never suffered from atherosclerosis-related diseases." 1998 G. Baggio.

[@StephanieMoDavis]

Hey Mike, thank for your service to us all. I have a question and would love your opinion. I am 47 trim and fit but history of lupus and kidney transplant (and dialysis). Started keto and feel great, all GI issues gone. My Doc is wanting to prescribe statins due to high ldl but also high hdl and low triglycerides. Uncertain from my history if lowering the ldl via meds is the way considering.

[@DrJK-wm9ec]

The Lipid Hypothesis is absurd. Too many black swans….The Clot Theory explains all the data.

[@Douglas-up2vh]

I'm 62, my LDL is 250ish.. Cholesterol 265. HDL/Triglycerides ratio is .68. MY Doctor advised Statins poison. I laughed and said HDL is 72, , Triglycerides 58. . Im 75% Carnivore. . No Bad carbs hardly. Hardly any veggies thanks to roundup. I power walk 2-3 miles everyday.I'll pass on statins Doc.

[@markwhite6782]

HELP WANTED- I'm not very educated in lipid levels. I changed my diet 2 years ago to ketovore and have totally dropped sugar. I just got my blood work back and was flagged with High cholesterol and high HDL. my blood work showed the following, Triglycerides-48, T-Cholesterol-266, HDL-137, LDL-119, VLDL-10. Is this something to worry about?

[@firstchoicefarm7767]

I certainly don't think so. That HDL is off the charts high and I've never heard someone say that's bad. Your tris are VERY low. Your T/HDL is amazingly low. As the video pointed out, LDL on its own isn't the complete story. How's the blood pressure and BG. Hopefully you don't smoke and you get plenty of exercise.

[@ketojiva]

This is excellent bloodwork. HDL is often called as teh good cholestrol, the higher the better. The most important factor is that tryglicerides should be low and you are right there!

[@DK-pr9ny]

Get a CAC scan.

[@CarlaGarner-lp5lj]

Do u mean that your hdl was 48 and ty was 137

[@markwhite6782]

@@CarlaGarner-lp5lj No, triglycerides 48, HDL 137

[@kelvinlum9883]

Thanks Mike Great health information

[@paulasykes4690]

I would like to tell your listeners about my cholesterol journey. The number one thing is ask your doctor to refer you to a Lipidologist or an Endocrinologist. Hopefully your insurance will allow you to ask for an ADVANCED LIPID. That measures the type of particles that are floating in your blood. I had it done. Secondly change your diet as the young man in the video mentions. I started walking everyday no matter what happens for 30m-1hr. I take Fiber powder daily, chia seeds, all types of nuts and drink a lot of water. Lastly, you have to try very hard to stay disciplined. I saw my Total Cholesterol numbers come down 30 points and my Good cholesterol (HDL) increase which is better. Always consult with your doctor. However, if he or she doesn’t know these things then you have to research yourself and be your own ADVOCATE. GOOD LUCK everyone. You can do it!!!!

[@toerag481]

I'm not a medical student or anything like that, but what I have learnt is the body needs cholesterol andd there are 2 types HDL (I think?) and LDL. HDL is the fat that providde energy and LDL are the repairs (if there ius a leak in veins from smoling, pesticides in food, polution etc. then LDL's come a long and fix to stop blood leakage into tissues)., hence to buil up of LDL in the veins as people keep abusing their bodies and it's a big money maker for pharmacutical companies to blame Fat. when every cell needs energy e.g. Protein 80% / Fat 20% with good fat being higher in producing energy so the brain loves fat as use more energy.

[@kirstylyons6328]

Im not a doctor BUT i have alot of experience with constant dis ease, unexplainable weight gain and nutrient deficiency from vegan diet, regular flues and infections and chronic gut and skin issues. NO DOCTOR or recommend diet or drug has ever helped resolve my issues that kept getting worse year after year. Out of fear and desperation to end pain in April 2023 i tried the high fat carnivore diet and it changed my life!! No debilitating arthritic pain and swelling, ibs symptoms are completely gone, my skin completely healed no more acne, dandruff or scericous. My hair and fingernails are thicker and stronger. Best of all has been NO pain from Arthritis, no more gut issues or body oders the deep refreshing sleep every night, 30kg weight loss and increased energy levels. I dont care what they say about cholesterol its made me healthier than ever and no longer fear getting old! I can happily and easily eat fatty steak for the rest of my life and will NEVER TRUST the word of a Dr a study or peer reviewed toilet papers ever again.

[@koala-py7uy]

This type of advice doesn't work for everyone. Keto 7 years, Carnivore for 35 days. I had recent blood tests and LDL was very high, HDL was low, Trigs were high, glucose was high, and two liver markers were high as well. Last test was 2 years ago and all those markers were either in the good range or heading that direction. Very confused now and concerned about plaques increasing. Looking for any thoughts people have other than to go vegan or vegetarian (they lie in their science [like in Forks Over Knives] and have no reliable RCTs showing anything conclusive).

[@christineng4938]

Low carb will reduce triglycerides and raise LDL. Eliminate carb to test it out

[@koala-py7uy]

@@christineng4938 LOL, clearly didn't read my comment, been low carb for 7 years.

I'm also confused I don't know what diet to do my LDL was 209 (low carb) I did a Mediterranean diet (169) it dropped but now I don't know which direction to take...

[@koala-py7uy]

LDL is mostly irrelevant. What is your HDL and Trig values?

[@missinformed4269]

Don’t let one test send you spinning.

[@DCGreenZone]

5. Conclusions In conclusion, our work demonstrates that SRP can attenuate the elevated inflammatory biomarkers (MCP-1, IL-2, IL-4, IL-6, and TNF-α), the production of MDA, ROS intensity, CATx, and GSH impact in the setting of LPS-induced vascular inflammation. SRP inhibits inflammation and oxidative stress through the endothelium MCP-1. We concluded that SRP has the ability to modulate vascular inflammation. Further studies will be required to explore the detailed mechanisms of the cardio-protective effects produced by SRP. These results suggest that serratiopeptidase may be a therapeutic agent for vascular inflammation in cardiovascular diseases.

[@rickmarek3840]

LDL is necessary for body function there must be something in the arterial wall to attract LDL to the particular site.

[@TT-y1b]

It’s calcium going into the arteries… not where it belongs… cholesterol tries to band aid it.

[@Ed-qn7vx]

High glucose is important but more but the real focus should be insulin levels.

[@skandashiva1805]

Thanks for the video.

[@tomninatriolo8085]

I'm in the process of diagnosing the why behind my recent heart attack...I thought it was heart burn. The cardiologist ordered bloodwork and wants me to eat 2.hrs before to see how my body is processing the food??? I can imagine what my LDL will be 😳

[@Vïkîng_Välörian]

I don't think these studies taken to a fact genetic predisposition to high cholesterol I don't even eat really unhealthy and I've tried all these natural products and nothing works to lower my cholesterol it's inherited in my family and I refuse to take statins I think sometimes it may just be uncurable have to understand how frustrated someone will get when they're trying everything and nothing's working

[@cgreer9010]

Learn what is your blood type. That will help you understand what you can and can't eat and when to eat it as well.

[@kainatijaz7641]

see dr. ford brewer channel , maybe he can help

[@paulhailey2537]

Nobody in my family has Total Cholesterol over 150. I'm trying everything to Raise my Cholesterol

[@user-kh8bp6ue8y]

​@paulhailey2537 any heart disease in your family??

[@tikibarry2279]

Try the Dean Ornish diet. Your diet is probably too unhealthy for your Family history. Or microdose the smallest dose of statin , twice a week. What is your BMI ? Overweight ? Eating only two meals a day and cutting calories is a solution. I've done all of these things. It works. Get your waist down below 36". .... It takes discipline.

[@noneyabusiness1054]

There was a reduction in DEATHS from heart attacks not a reduction in the number of myocardial infarction. This mortality reduction was related to the advancement and increased access to cardiac catheterization. It was most significantly affected by the invention of drug alluding stents. It was NOT the conversion of consuming industrial seed oils.

[@georgek3627]

I was able to get my triglycerides down on carnivore from 199 to 56 my HDL won’t go up no matter what I do, HDL 56 LDL high of course, I have plaque I did cac scan, have trained all my life so active, it made no difference by the looks of it, from what I understand I should be reducing my LDL, I really don’t want to take statins, I already have prescription in my pocket, this is just fucked up, its impossible to avoid saturated fat on carnivore, what is the point eating red meat and fat and then swallowing a statin straight after, so confused on what to do. Thanks for the video I really needed it.

Did you manage to reach any conclusions? I live in doubt, I did low carb and my LDL was high at 209 then it says Mediterranean diet I lowered it to 169 (still high) my triglycerides at 90 HDL 53, I don't know what to do if I don't eat fat sw I avoid it I like meat but I confess that I'm always afraid of being wrong... but I definitely had to avoid sugar and flour and take natokinase berberine k2 supplements, etc.

[@georgek3627]

No unfortunately, I am taking supplements like natto, high dose of vitamin c, beetroot powder, you need to do a cac scan to know if you have a plaque or not, cos if you don’t, then you should not worry about your LDL from what I understand, but your bloods look similar to mine, I guess low HDL and high Triglycerides is worrisome. I am working my way towards becoming Lean mass hyper responder, my lipids looking similar already, I just need my HDL to be higher, I think then high LDL may not harm me any more, you could try red rice extract and citrus bergamot shown to lower LDL.

[@ldx1793]

I am 53 years old now and 1 year ago i did a cac score and it was 524. Also,an ultrasound on carotid arteries in the neck,the right side a had a mild block. I went carnivore ,like 99.5 % for a year and retested both. Cac went up 100! total became 624 and the mild carotid plaque grew from mild to not mild(forgot the term) So, with my cardiologist we did a heart cath and discovered 2 blocks of 60-70percent -one in the right coronary artery and 1 in the left anterior descending coronary(the widow maker) artery at the very beginning of it. Anywho, so, for me i started 80 mg atorvastatin and it definetely cut my ldl down to 68. So,cardiologist is happy. Im hoping he's right and wont need stents or more. Also, switching back to a normal diet,but a lot lighter on the eggs and red meat, and meat in general. Will test all again in a year? If im so lucky.

[@georgek3627]

@@ldx1793 thanks for sharing, it’s really hard to make decisions when you are facing this, it’s hard to know what to do, please update when you re test, I think it’s really important to share info, cos we can see what works and what don’t.

[@koala-py7uy]

There is some evidence that with a decent amount of K2 it can help reduce or harden plaques. Look into it if you want to know more. The research is still pretty new so they will not promote it without more study.

[@michaelharrison2775]

Statistically people with high LDL outlive people with low and I don't think cholesterol is what contributes to plaque buildup

[@michaelharrison2775]

But you touched on it it's the vegetable oils that stick to the arteries

[@nerolowell2320]

Rubbish report!! They blame the cholesterol but they never speak about the ultra processed food, refined sugar and vegetable oils

[@indavietual]

My dad and mom both have high cholesterol. 65 and 62 Yo. I'm 39 yo male 5'8 155 pound, Tri 196, HDL 43, LDL 326 tested two days ago. Workout twice a week and throw in some cycling here and there. Eat lots of eggs, beef, chicken. I use olive oil, beef fats, chicken fats to cook my food. I dont want to go on statin. From what I'm getting LDL isnt really the issue. Just have to focus on things that damange the artery walls, and high blood pressure. Mistake to not take statin?

[@JohnnyRocketone]

Why dont you mention that some people have extremely high LDL and have no disease. Talk about that!

[@JoeS97756]

Yeap and some people smoke all life and never get cancer and some people drive like an idiot and never crash. So what's your point, do you feel lucky?

[@porkpie2884]

@@JoeS97756 Smoking is causal of disease. LDL is not causal of disease. BIG difference

[@Smitness]

Do they? Electrolytes? Improve creatine utilization?

[@keithcitizen4855]

Ref processed food - an innocent looking blister pack chicken n lettuce sandwich includes a long list of additives similar to sausages

[@Cacheola]

Stay hydrated

[@kimcooper7552]

I don’t drink, not eating sugar , don’t eat ice cream baked goods. Rarely bread. Exercise is the only thing I’m not doing good at. And I my LDL is very high. Told probably genetic.dont want to go on statins because my body reacts to almost every drugis really

[@JohnWilliams-gy5yc]

I'm amazed that Ancel Keys's remmants are still resonant up to these days. If you think about it, you will find that his hypothesis is wrong and too naive at the 1st place. The root cause is changing (in a wrong way) of *_MODERN LIFESTYLE_* . I'm also amazed that people think they still can reduce LDL to close to zero with drug intervention while staying on a couch. The Occam's razor seems to have 2 edges.

[@lindabirmingham603]

Well done! Perhaps next time clarify right away that LDL is not a type of cholesterol and stop using the misnomer "LDL Cholesterol"? Just say LDL or LDL lipoprotein. Dr Malcolm Kendrick has extensively studied plaques and noted that less than 1% of the plaque tissue examined consists of cholesterol. The rest is layers of blood clots. I used to dissect people and people parts for a living and this is absolutely correct. Large plaques in the aorta were alternating bands of pale yellow rubbery tissue and dark red softer layers. Reminded me of tree rings... Another common cause of damage to the arterial lining leading to clots, then plaque, is uric acid. Fructose is broken down into uric acid causing crystal formation that is carried in the bloodstream. High blood glucose also causes the liver to convert excess into fructose via the polyol pathway. It is also reasonable to suspect that oxalates would do the same, as they form crystals with calcium and magnesium. Both types of crystals look like needles under the microscope. I read a small study from autopsies done on HIV patients with atherosclerotic plaques. The plaques were analyzed for oxalates and the plaques were loaded with the crystals. Unless tissue specimens are processed differently than the standard procedure, the crystals dissolve in the alcohols. You can microscopically see sharp outlines where the crystals were, but won't know what kind of crystals unless specifically processed and stained.

[@suemcgann]

I have been told I have low tricyclycerides and high LDL. I am in the uk and very confused and don’t want to go on Statins

[@gon7155]

Youd be so dumb to take statins

[@Martihorn]

Get out all sugar and grains. You are fine.

[@porkpie2884]

Low triglycerides and high LDL is just how it should be. Never take statins, they cause disease kzbin.info/www/bejne/n4Dal5t8jLqqnqc

[@olabisidurojaiye]

Berberine .vitamin D3 and K2 Uk is useless everything is satin. Exercise low carb diet

[@ezloop1]

great video.

[@terrycameron9728]

Hi Mike I enjoy your podcasts and wanted to ask you something about Creatine. I notice your electrolytes gas Creatine in it. I’m 68 yrs of age female who has quite fragmented sleep. Previously when I was taking Creatine I found over time that my sleep hunger reduced to almost zero. Have you heard of this and do you have any advice as I would like at avail myself to the positive aspects of Creatine. 🙏

[@alexanderkeber4257]

I got prescribed Crestor and one of the most common side effects is diabetes! No thanks.I’d guess that diabetes is a lot worse than slightly elevated levels of cholesterol.

[@kathygreer2097]

Where can we find a doc like this?😊

[@yeangh-y]

You mention high blood pressure and insulin resistance as risk factors. Are they independent factors, since hypertension might be a result of insulin resistance? What is needed is a multiple regression analysis where one factor is held constant. We can then see if the second factor is still significant.

[@mimiwilson2097]

I think you have to look at LDL broken down into small dense or large buoyant…..hubby his 197 LDL,but his small dense is less than 90….so he has mostly large buoyant ….not a big cardiac risk

[@larsnystrom6698]

Most MD will read that research as support of the lipid-atherosclerosis hypothesis. The will ignore the artherio injury "footnote", because that's not treatable with medicine. This entire business has been too infected to be cleared up in decades. Too much research even treat LDL as an valid endpoint. That's no way to progress!

[@alan2a1l]

Talk about begging the question. They ASSUME LDL-cholesterol is the causitive agent, in the presence of other inflammatory agents, with no regard to oxidation or glycation of the LDL. It's motivated reasoning, ie biased analysis. Crap science. You know this, Mike! I know you want to be careful, but this LDL-cholesterol model is seriously flawed. Your dietary advice, however, is spot on. But the heart-cholesterol model is garbage. (Okay, you finally got there.)

[@samulmagnus1]

Triglycerides 69 HDL 85 LDL 263 Is this good/bad? Any suggestions?

[@1timbarrett]

Very good

[@porkpie2884]

Great.

[@Donna-iu4lq]

Thank you for this information! I have elevated (small particle) LDL but my LDL/HDL ratio is great, fasting insulin is good and APO B is 80. I have low BP, don't smoke, not overweight and eat well. Am I correct in saying LDL isn't thought to be a concern unless it is oxidized so keeping inflammation low is key. Am I overly simplifying?

[@videoshare5521]

I am concerned, I went carnivore and keto vore 4 months ago, and I just received my blood test back 7/2024. My triglycerides went up from 72 mg last year, to 175 mg this year on Carnivore and keto vote, what the heck?

[@karen_yee]

My LDL is 303, HDL 94 and Triglyceride is 44. Should I be concern of the LDL level?

[@KayFabe87]

Probably not. Your Triglyceride to HDL ratio is excellent. Perhaps a CAC test to confirm that you don't have any calcified plaque buildup just for peace of mind.

[@karen_yee]

Thanks for the suggestion and that is exactly I am going to test in 1 week time on my 3 month mark of going carnivore.

[@markomarko4327]

​@@karen_yee What were the results? If you don't mind me asking

[@apadora]

ahh.... the classic..."create fear" and buy my stuff 🤣

[@dennisward43]

Check this out by High Intensity Health above, if you haven't already seen it. High LDL Cholesterol = Lower Risk of Death: NEW 22 Year Study