How bacteria "talk" - Bonnie Bassler

[@evanpalmer3594]

That was one of the best explained TED talks I've ever heard

[@soniabarrett]

I absolutely agree with you! Really great job!

[@Lili-yz6xf]

Timestamps/vocab: Vibrio Fischeri- 3:09 Bioluminescence- 4:09 Quorum sensing- 7:13 Intraspecies communication- 9:18 Interspecies communication- 10:49 Esperanto/ a universal communication molecule- 11:31 A new approach to antibiotics- 13:45 Quorum sensing in bacteria- 14:43 The gang- 17:11

[@vishnuyella5058]

Goat

[@casey-gt8nl]

LETS GOOOOO

[@kaitlinmatrix6473]

The way she speaks about the young researchers is amazing. Genuinely made me tear up! I don't know what I'd do if my PI talked about me like this

[@maevedarly]

I know 🙌🏾

[@mientrant3615]

Not just the great information she gave but also how incredible she talked smoothly energetic non-stop in the whole speech.

[@srimansrini]

Ms. Bonnie Bassler gives one of the riveting talk about how Bacteria communicate with each, a study that will propel the future of medicine. This is one of the finest studies ever conducted and hats off to the Princeton team of young innovators.

[@pseudomonas69]

Doctor Bonnie Bassler........

[@RitaPizzi]

Prof. Bonnie Bassler

[@gopikapj4255]

i love the way she present the topic, it makes curiosity in learning about that subject.

[@osmosisjones4912]

You should see my movie Osmosis Jones

[@tutentDotCom]

I got excited about this just from listening to Bonnie talk about it. At first I thought she was nervous, but then I realized it was just her and her excitement for her subject. And her down-to-Earth analogies made it incredibly easy to understand. Thanks so much for sharing this presentation. I learned a lot!

[@anraiduine1483]

Man that symbiosis with the squid is just wild!!

[@angelikahainz1665]

Die ganze belebte Welt besteht aus Symbiosen, würden sie sich auflösen, blieben nur noch wenige Einzeller übrig. app.you-publish.com/render/index/guideStaticId/58606d6c62d6789939176d5f/type/pdf?fbclid=IwAR0UbB6irSbNdT7tI_usHAVa9k0Pi-bggaUhKnneavhTj5SRe5sD6kMduss Lesestoff

[@ValeriePallaoro]

I love the conclusion; that the conversation can go both ways. Her team are developing both - away to stop bacteria from talking to each other (protect us from them) and a way to encourage their conversationability (protect them from us) It could so easily have just gone the one way. Nicely done. And much appreciated.

[@mabelspeaks8019]

Thank you for attributing the students who are doing this important work. So often the students who do research as part of a class don’t know that other students are being directed and taught by amazing instructors-some of whom- may not be as diligent about honoring them early on.

[@oinkbaamoo]

Fascinating subject. Brilliant speaker.

[@osmosisjones4912]

You should see my movie Osmosis Jones

[@jerkman4jesus]

Its the twentieth century and our most breakthrough discoveries are still happening because we saw a light. Excellent research, groundbreaking discovery and I hope what will be the foundation of our medical treatment of the future.

[@AbhilashNairSpartnax]

21st but yeah

[@snaggingllama924]

Hello Fellow AP Biology Students

[@slayz5296]

greetings

[@Pickled_Poptarts_53]

Helloo

[@kuulraccoon]

Howdy

[@emilypaucar5945]

Welcome 🧬🔬🥼👩‍🔬

[@amandareis5032]

Hey!

[@fernandoartiles9875]

Amazing! A very passionate scientist, an incredible and enthusiastic teacher! A "must see"!

[@patrickfaas2329]

Bonnie Bassler is wonderful.

[@thenightking7167]

This must be the absolutely most wonderful presentation in TED's history. Dr. Bassler, you are a remarkable human being, and scientist. Thank you, a quadrillion times, for acknowledging the invaluable contributions of every member in your lab. That was an indescribably beautiful gesture. 🧬🔬

[@LionTheHeart]

This lovely intelligent lady is definitely in the right career. Fascinating! Thank you

[@gracecy8010]

wow i didn't know bacteria were so complicated this was a very good talk. I understood it well.

[@HeCtorCapitalCe]

They don't always give a standing ovation, everyone chooses as (s)he wants. It's just a testimony of her speaking abilities and the riveting facts she brought forward. You can dislike any speaker and their subject, but for me this format is of so much value.

[@syncflame]

Here I am sitting in micro class, imagining bacteria sharing memes :D

[@DubbedDemon]

I thought I was watching this at 1.5x speed for a second

[@hdb80]

She's passionate, and has a TON of info to give in next to no time.

[@marieahlin1718]

Yes, I thought about how much she must've practised with a stopwatch to get all info in, in time 😀💪💪💕

[@ValeriePallaoro]

Wow ... I thought it was perfect timing. Gave me everything and conclusions at each steps to allow me to go on to the next step with her. Nicely done.

[@RondaldJames8]

I'm watching it on 2x, and it's wonderful, still coming thru clear ❤

[@HS-wl6bu]

I got so touched at the end when she recognised her brilliant "gangs". People sometimes forget to acknowledge but she didn't.

[@oliverlittle5028]

She adapted the Dazed & Confused quote: "Thats the awesome thing about high school girls; as I get older, they stay the same age". Fantastic speech Ms Bassler!

[@Kerrsartisticgifts]

The best Ted talk ever!

[@JackSparrow-ld6rz]

Everything about this speech was superb. I really enjoyed everything she had to say. Really was one of the most entertaining talks that I actually really liked.

[@kittenforbunny]

Absolutely f'ing excellent talk!!!!!!!!!

[@rachelcitizen4703]

Wow!! What a fantastic presenter and she explains it so clearly. Excellent. Thank you heaps for the upload.

[@rolo1363]

I'm really surprised this isn't more famous, it's so cool!!

[@ShallowBeThyGames]

Never thought of other "friendly" bacteria, always thought that "probiotic" stuff, while having an element of validity was blown out of proportion regarding it's benefits. Suppose I should do a little research on it, starting to find this whole immunology and virology quite interesting. Thank you very much for setting me straight.

[@soniabarrett]

I really loved this, one of the best TED Talks as Bonnie did such an amazing job of explaining the journey of bacteria so simply so that one one can understand it. Really great!

[@haileywilson6596]

That was the best TED talk I've ever heard

[@BerkeHitay]

9:36 Species specifities! My favorite moment in any Ted Talk!

[@muhammadsiddiqueafridi8358]

You know what last night I was reading about quorum sensing and read many kinds of stuff to get know about that but in vain, and yes now I got to know what quorum sensing is exactly. thanks for such a mesmerizing way of your explanation

[@dilliganesh.m.3915]

Your lecture is soo energetic. I felt learning something new. Your talk is very informative and it's amazing discovery.

[@karencorkery5574]

Fascinating how Bonnie can initiate such excitement and curiosity about cellular structure and their existence. Makes me hungry for more.

[@brianfoley4328]

I've seen Prof. Bassler on another You Tube channel....she's brilliant.

[@Abominatrix650]

I have to do an essay on bacterial biofilms and communication plays a big part of it. This video is great at helping me!

[@superbere]

Wow. I am a few years late to this video but this was one of the most interesting videos Ive come across on youtube. She is fantastic.

[@cathysissens9248]

Phenomenal speech! Beautifully explained and riveting! Had me hooked from the intro...

[@salahhe]

One of the best Ted's. Good job!

[@aaliya9652]

The best Ted talk ever 👏

[@fractalico]

Lady, you are brilliant and charming...you explained so graciously a fascinating and profound aspect of life!

[@thisone45]

I love this stuff. Just the idea of giving a person with a fatal bacterial disease time enough to fight it off is amazing. I could be wrong but it also seems possible to allow a person to go on living a normal life while suppressing a disease indefinitely if they couldn't beat it outright.

[@F00dstamp96]

Fantastic video!! I love the way bonnie describes things.

[@WidedHadjeb]

I think it is the best explanation of Quorum sending i have ever seen thunks a lot

[@TheStallion1319]

great talk enjoyed her enthusiasm and the valuable information and the advancements they achieved

[@LDWcoment]

Great talk , best Ted-ed i have seen .And they are all pretty amazing.

[@michellewilliams736]

Her passion is so inspiring!!!

[@euneillabrador3154]

I am currently learning this in my Microbial Biotechnology class. She made this topic more interesting for me to understand!

[@racekarts]

A super excellent talk Bonnie, thank you

[@ajnjmar1]

Amazing! Well done Bonnie and well done Bonnie's gang at Princeton.

[@stevedunn90]

TEDtalks is the actual organisation that runs all of these lectures. This channel is an editorial of videos that are educational, so people that are interested in specific areas can get related videos. There are loads of different TED channels, but all are fed from TEDtalks.

[@amanlitt8386]

for how excited and passionate she was throughout the entirety of her talk, her outro was pretty meek. Thats us science nerds for ya

[@zachrawlings6523]

Soo many interesting facets of this talk. Love it

[@BxSquared]

She is so passionate! Love it!

[@GoPieman]

She doesn't relate to bacteria like "some complex animal". She doesn't say they're more important than animals. She uses expressions like "talk" to put across her message in a more fluid way, and adds some fun...nobody actually thinks bacteria talk or can think at all. She's excited because these are important scientific conclusions, understanding interaction and the game changer that is to manipulate bacteria like this.

[@VeVoRose]

Mind is blown love this stuff!

[@squidb8]

So if we tamper with inter-species communication, would that affect beneficial bacteria also?

[@D3sertst0rm]

I did not miss your bigger point. You did mine. I do read books, search the web and watch tons of hour long documentary series and yes there's not nearly as much information on an 18 minute clip. However there's a lot of diferent ways to retain information and/or being able to integrate that information with previous or future acquired knowledge (topic too long). In any case, any thing from this 20 min clip will be more valuable than your next reality show/soap opera can offer.

[@lillazyboi]

My question is: Just like how bacteria can build resistance to antibiotics, can they also counter the quorum sensing block? Bacteria are very smart

[@avinashsunder5176]

+lillazyboi actually, they have the potential to develop resistance - but it would probably (and hopefully) happen only after widespread commercialization and overuse of the QS blocks. Then we would have to discover the next anti-bacterials..

[@lillazyboi]

Thanks!

[@richardeldridge8335]

+lillazyboi I don't think in can be countered. Bacteria immunity is the result of non-immune bacteria dying off. The survivors don't develop resistance, they already have it. As she stated in the video, antibiotics select for immune bacteria. What is happening here is that a molecule is blocking the receptor to the quorum sensing molecules. It would have to develop a brand new receptor, and at the exact same time, develop a brand new communication molecule, and that's never going to happen. And, hypothetically, if it did, you'd only need to block that new receptor.

[@iluan_]

They could by developing mutations that change the type of molecules that control quorum sensing as well as their corresponding receptors. Which is good news since that would require a lot of changes instead of just requiring getting a plasmid or two, which is the case in the resistance mechanism of many current antibiotics.

[@hdb80]

Good question.

[@haripanditparanjpe30]

This fantastic presentation was around 6 yrs ago but still nowhere near new line of antibiotics. Why ?

[@TheKillerGamesTkg]

I'm sorry to say but it has its reasons that anything that involves human trials and such take a really really long time 10, 20 or more years

[@wwitsel]

What an excellent explanation

[@yocahuna]

Wonderful presentation on so many levels. Naturally, the ones i focus on demonstrate the PANACEA system: the idea of independent holons that make up a holarchies, data exchange, cooperation and emergent effects. The sovereignty of bacterial communities is recognized and a NPV index is assigned to them. (Don't envy who has to count them.)

[@BrianSiegelwax]

Honestly, I clicked like as soon as I saw the Mac. The rest is good enough that I've already seen this content replicated quite a few times across other channels.

[@saldasinkope3002]

A small update on the fact about the resident microbes and the human cells- It's more like 1:1 ratio between them not 1:10.

[@lillazyboi]

+Jānis Galdkājis True. My microbio professor just told us this lol.

[@nikop4617]

1.3:1

[@MohammadAhmad-fi3pt]

She seemed so surprised when everyone stood up for her!

[@MosesGTC]

Realised that there are more bacteria around me, in and on me than my body cells.. and these bacteria interact with the environment, and my cells...hmm where does my "self" begin, and end? Interconnected, inter-dependant, all one organism..?

[@mikemeriwether9495]

This assignment was very balls, I love balls.

[@D3sertst0rm]

Another possible mechanism is what Vincent W, very well said, the enzyme production trigger might be associated not only with quantity but also with density.

[@Hemel29]

beautifully articulated and amazing persona !! thank you for doing what you do.

[@spokehedz]

If half of the teachers in this country were like her, I have no doubt that we wouldn't be falling behind on our education scores.

[@bdhome2010]

Respect from BANGLADESH. Thank you for such explanation.

[@threebythestreet]

POV: You are watching this video because your connections academy Unit in Health Sciences is telling you to answer 5 questions based on what this Ted Talk.

[@nathanhasbani7877]

Very interesting and such an articulate speaker

[@diegofernandoecheverrigarc52]

Prof. Bonnie Bassler and team, thanks a lot for your excellent presentation. Is there any evidence or examples of these "communication molecules" in processes (digestion, immunity, vitamin synthesis etc) mediated by the human microbiome? thanks!

[@eniamrahc73]

Really interesting talk! Excellent speaker as well. Would love her to be one of my microbio professors.

[@vinitajagtap1918]

Really awesome talk

[@lily772]

Bassler will definitely win a Nobel prize one day

[@Zaris1021]

attentive to the end.. awesome speaking! well done

[@patricksullivan6264]

Einstein chose Princeton. Dr. Bonnie Bassler chose Princeton. Total geniuses.

[@ssirajd]

Great for a understanding, knowledge on the Bacteria and works good for a basic understanding the most important living beings that bless and trouble you by being around you.

[@DEVIKRISHNAS-g4e]

Ms. Bonnie Bassler.....this is one of the best talks ever....well explained as well as interesting...Thank you so much

[@SeleneBeatty]

We as humans could take a lesson from these primitive organisms.😊

[@SeleneBeatty]

16:38

[@DaRealFiberOptix]

awesome. i love the metaphors you can draw from knowledge about bacterial systems

[@santiagogonzalezbenjumea9880]

Amazing talk

[@porculizador]

i think kary mullis' molecule approach to killing bacteria is the best way to compensate for the demise of antibiotics but this research on how bacteria communicates is amazing and very promising too

[@VegaChastain]

The main thing that scares me about GM and GE foods is that any DNA from them that isn't denatured by our stomach acid (this can be a lot depending on the health of stomach secretions, which tend to be quite unhealthy in an Americanized diet plan) ends up being absorbed by the bacteria that inhabit our intestines. These bacteria are imperative to many processes within us, and are integral to our immune system, vitamin B and K absorption, and many more important processes. It is estimated that these gut flora have around a hundred times as many genes in aggregate as there are in the human genome. This is what you want Monsanto to be experimenting with? :-/

[@elisabetabaltaretu4259]

Excellent explains..congratulations

[@CarolRadway]

Wonderful, mind expanding talk.

[@CarineFrisch]

Beautiful. Thank-you. And very interesting: stuff I never heard about .....

[@subhamsinha3]

Excellent video 👍👍

[@marzbar5941]

The key to our humanness

[@CLEANDrumCovers]

This was fascinating.

[@yasminazaadeh4177]

Just when I was beginning to think anti biotic resistance would wipe us out.

[@samreads]

In any case that would never happen. Just as some bacteria evolve anti-biotic resistance, there would always be some humans who'd be naturally able to resist that bacteria. So while the "weak" humans would die off, the survivors would thrive and their future generations would be naturally resistant to that bacteria. And the circle of life would continue exactly as if nothing ever happened.

[@chaz4510]

Unfortunatly as a teacher I can testify to the fact that many children have no imagination for science or are kinesthetic learners. So nothing would be less effective than being leactured, even by a speaker as amazing as her.

[@8906384]

That was an awesome talk!!

[@rogercorneau4379]

Great talk

[@kimpeater1]

First of all, this is not fake knowledge; these talks are here to enlighten us about the frontiers of science. Secondly, TED talks are not meant to teach everything there is about the subject. It's meant to engender an interest to dig deeper. I think they do a pretty good job. You can't really learn something without being interested in it.

[@rah5012]

Harrisburg University sends our thanks for the information!

[@kimpeater1]

I thought about that too. I wonder if the infected person, even though the bacteria is "dormant", would that person be contagious and spread the bacteria to others?

[@AbhilashNairSpartnax]

Impressive how a minute stuff takes on a host million times its size