How these molecular machines make life as we know it possible

[@Nanorooms]

Go to surfshark.com/nanorooms for 4 extra months of Surfshark

[@myrmatta1]

Some constructive criticism: when you are talking about a specific part of a protein or other molecule on screen, always make sure to highlight that part of the graphic. Something as simple as an arrow or circle would be very helpful. There were a few times in this video where you would be explaining a specific part of a protein, but there would be no indication of what part you were referring to. Unless the viewer happens to be familiar with protein structure and terminology, its easy to get lost without highlights.

[@Nanorooms]

That’s totally fair. The production was definitely rushed for this video cuz I was in job search hell for most of it. So sad that it affected the quality of the video :(

[@myrmatta1]

@Nanorooms rushed production makes sense. It happens.

[@teunschuur7988]

You know, you inspired me to do the Nanobiology study. I'm in the third year now and I think this was the best decision I've made. Thank you for your work, keep it up!

[@Nanorooms]

I’m glad I did and I’m glad you’re pursuing this too!

[@StellarIncarnate]

This is quite possibly my favorite channel. Very easy to follow along, A lot of care, effort, and time put into them. Narrated by cute disembodied nerd voice. Yet so underrated it's heartbreaking.

[@Nanorooms]

Thank you! I hope I can continue to make them better and better

[@chemistrycapital]

Lonsdale would be proud of the benzene representation in those molecules, some awesome animations too!

[@bioversechronicles]

I loved the drill bit analogy! As someone who's also starting out making mol bio videos, I am always looking for simple analogies. In my AlphaFold video, I used "differently charged string of beads floating in water" to explain protein folding :D

[@Clockworkbio]

Ugh I hate being the second poster of the day

[@lucash7012]

Ooh does this mean we’re about to get a vid from you too 👀

[@DanteGabriel-lx9bq]

We're waiting Clockwork. 😉

[@StellarIncarnate]

CLOCKWORKBIO!? I swear I wasn't watching NanoRooms! I was just passing by! Who am I kidding...

[@Nanorooms]

We’re all friends lolll

[@hrishikeshaggrawal]

So basically, protiens are large inu shibas holding miniature inu shibas and saying "now kiss".

[@MrDesperadus]

Awesome video, thanks

[@2011vortex]

This video was great!

[@gabriels.9088]

I love this channel

[@NorthCalm]

your videos are very interesting

[@ЛешаТитов-ю7с]

Great video! Since it is an introduction to protein structures, it would be neat to see how exactly are proteins composed from smaller parts. Like, how amino acids come together to form the structure in the first place, without the helix/sheet simplification.

[@anirudhkashikar2300]

Excellent video. Congratulations

[@Filaxsan]

WOW! This was amazing!! Thanks dude

[@EviLPlayeR04]

So, I’d like to start in the field of protein folding but don’t know where to start… I know Alphafold is a tool that few are ready for with its huge potential applications. I would like to use it and I learned how the program works overall. My question is: How can I get the knowledge to use this tool? Which courses (online if possible) can I take? Thanks in advance!!

[@bobspianosbffl]

Amazing content It's great you're sharing this information in such an accessible way I have a small critque. The animations are a bit jarring, with too many things moving, appearing and rotating. This gives me the sensation of being overwhelmed. I can't give a simple solution since it is a matter of artistic choice. Some animations are crucial but stripping out as much unnecessary visual information as possible while keeping it beautiful would no doubt increase the amount people enjoy your videos. A specific example is at 4:13 I'm already overwhelmed by the amount of information I'm getting, that having the box outline get drawn in and the amino acids move into place is extra unnecessiary stuff that my brain has to decide it's okay to ignore since that's meaningless with respect to the lesson. It takes a split second to parse but this sort of thing is happening on almost every frame and it makes the experience less pleasant by adding mental load. Especially when so many animations do convey meaning, like an arrow appearing, a bond breaking or atoms shifting. It makes the meaningless animations stand out even more. I like your style a lot and I can see this took a lot of effort to create but also keep in mind cases where less would be more.

[@potatolard9643]

I would love a more higher level video, this explanation was beautiful but I have heard it many times and believe you can produce very good technical content

[@GeoffryGifari]

Wait... so a target protein needs to be unfolded into an amino acid string for chymotrypsin to cut it?

[@Gelatinocyte2]

I think it's only unfolded in this video for clarity sake. Although, the proteasome _does_ unfold proteins into a string.

[@crisrampante647]

Molecular biology forever

[@Rudol_Zeppili]

Lovely video and explanation on enzymes! Also the jujutsu kaisen references were great lol, I somehow expected you to make one when you mentioned pocket dimensions and rules 😂

[@meg.h.]

which video did the mcd burger flipper guy comment on?

[@Nanorooms]

The beauty of life from the lens of physics

[@23蔡冠霆]

How do you make these animation. Which tool did you use. (2:31)

[@GeoffryGifari]

So a drug can work by blocking an enzyme's active site? Can a drug modify an enzyme's structure permanently?

[@myrmatta1]

Yes they can! Though most of those are classified as toxins...

[@ValidatingUsername]

How many segments are made concurrently so the folding doesn’t interfere with each other like parallel processing 😂🧐 probably as many start and stop codons are in the genome for that protein to make a larger structure 😂

[@delauro11]

great

[@1.4142]

I know what's going to be the most viewed part of the video

[@1110-d3r]

🎉🎉🎉❤❤❤

[@JetFightzer]

This video is surprisingly less clear and harder to understand than the other ones 🤔

[@MartinDlabaja]

Confusing explanation! Seems like visualisation did not correspond to what you were saying and did not help!

[@taylorgardarian]

Is it nature's design? It may be one way to say how the approach You start sees time. Consider a future approach which links causal time and reversal of the causal chain to actively defend reverse appearance of each target molecule. The trail is visible.

[@Ortorin]

As a layman, his is the least understandable video you've made so far. Where even is the "s1-pocket" in your graphic?