Howard Chang (Stanford, HHMI) 1: Epigenomic Technologies

[@mmartin5816]

Wow, what a tremendous series of advances. It seems we have a new level of insight on epigenetics. Well done Dr Chang

[@DG-xg8vg]

Fantastic information, of which I only understood about 5%

[@hgz11]

That's why I love this channel....they don't dumb it down. You'll get it DG.... it just take stime

[@RoverT65536]

Fascinating

[@juanpablomorantorres1903]

Sweet mister

[@metalwellington]

interesting

[@numericalcode]

Cutting edge science

[@EmmieAfra-y5l]

Martinez Margaret Brown Laura Thomas Angela

[@so-oo6ti]

Japan is trying to discharge radioactively contaminated water into the sea, and I'm curious about this part.

[@Breal1969]

For you over thinkers: The man spoke clear and concise. You don't even need to have any background in medicine to keep up Tik Tockers.

[@ardd.c.8113]

Okay tough guy

[@Rishab1702]

Anyone from India watching this?

[@lifestylealignment4180]

Watched

[@Rishab1702]

@@lifestylealignment4180 so what are you doing job or research and in which field?

[@lifestylealignment4180]

I am IT pro but have super interest in biology, what do you do?

[@Rishab1702]

I am doing bsc in biotech second year. But really man it's quite fascinating to c people like u who are curious to know everything even if it's not there field.

[@lifestylealignment4180]

This filed is called Life Science, for a reason they have named it Life 🙂, by the way I have enrolled for MSc Bio technology, just for my passion soon hope to shift my job in Any medtech/health tech.your BSc is best career path, study and master every word in your text book rest all will fall in place naturally

[@kipling1957]

Scientists get hung up un the underlying technology when explaining their expertise to the general public. I just want the headlines first, with some useful analogies. I can choose to peel the onion for detail as I understand its relevance. This is how learning happens. An onion model, not a detailed linear description. I understand why they do this, habitually, having to justify conclusions to their peers. This talk is better than most. But the big picture elements of the whole presentation could have been sketched out in the first 5 minutes, with some detail drilled into later. But do we really need to know the bench-level steps for ATAC sequencing of nanoliter droplets, for example? It just creates fog for the non-expert. I can pull a paper should I ever be curious enough about this level of background detail.

[@l.christoffersen7502]

This is nowhere near bench-level steps. You cannot understand the big picture without understanding the details, even if you think you can.

[@pavellambracht5823]

@@l.christoffersen7502 but in order to make people understand you HAVE TO start with a big picture. I am completely agree with kipling1957 on this. Make some useful analogy, make it related to people somehow, hook them on to this topic and then get into details. Over here in this video there was no hook whatsoever. ATAC protein right away... You need 4 year Bachelors degree in biology or genetics, or something related to get it. Now, I have a question, who is a targeted audience in this type of videos?Students in college? High Schoolers, or colleagues which have PHDs... I am pretty sure colleagues don't need it and those who are in colleges and high schools will not get it or there is much simpler videos in regards of the same topic.

[@kipling1957]

Ala Nine I agree, generally, but there is still to much back-detail in this presentation. I’m talking about HOW you roll out the menu to the public. I was a bench level biologist for two decades, so appreciate the point you make. But with family and friends I don’t immediately pull out my co-IP gel photos to elucidate an important phenomenon. That comes after dinner for the curious.

[@l.christoffersen7502]

​@@kipling1957 But the title of the talk is literally "Epigenomic Technologies". He briefly explains what epigenetics is in the beginning and then describes technologies with which to analyze epigenomics. I get what you're saying with friends and family but at the same time maybe this video's target audience isn't your grandma.

[@kipling1957]

Ala Nine Grandma, no. Educated non-expert in the field.

[@hraqhraq]

Does not have good explanation or details, also he was pointing to things non precisely to what he was talking to at each point of time, more like he was talking to his colleges in Lab