SuperAntigens

Superantigens are a class of antigens that cause non-specific activation of T-cells resulting in polyclonal T cell activation and massive cytokine release. Superantigens are produced by some pathogenic viruses and bacteria most likely as a defence mechanism against the immune system. Compared to a normal antigen-induced T-cell response where 0.0001-0.001% of the body’s T-cells are activated, these Superantigens are capable of activating up to 20% of the body’s T-cells.
Superantigens bind first to the MHC Class II and then coordinate to the variable alpha or beta chain of T-cell Receptors

[@venuskataria5230]

Ohhh my god...this is literally amazing...God bless you ...

[@hussainbiology]

thanks Venus for appreciation... God bless you too

[@akashpandey7235]

That was really nice... bt u need to work on ur pronunciatio.... that makes it hard to understand..... And thnk u for the info...😊

[@hussainbiology]

Thanks for appreciation..and definitely i will work on pronunciation

[@zadengoofy]

I guess our teacher is from kashmir. And many words are pronounced like that only in kashmir region.

[@ubairaaltaf1324]

Assalamualaikum. Sir plz make videos on elisa, and western blotting

[@hussainbiology]

Waliekumaslam Ubaira.... InshaAllah pretty soon i will be making these videos .....

[@habibazaibi1932]

This is very helpful; i also think that adding captions to the video will help a lot processing the informations . Thank you ❤

[@hussainbiology]

thanks for appreciation...Glad to know that it helps

[@Dra.materosa]

good explanation, terrible accent

[@hussainbiology]

Sorry for that

[@chetalirupela568]

Such a good video

[@siniorashani]

❤❤❤❤👍

[@prathameshahirrao8106]

Thanks sir You are my favouraite momedian after Abdul kalam sir

[@hussainbiology]

thanks for appreciation..Glad it helps....✌️

[@yousefmohamed5714]

Very useful but if you enable caption will be better for other nationality my good wish from Egypt

[@hussainbiology]

thanks for appreciation.....and i will consider adding captions

[@stephaniezhang6272]

thanks a lot. This is great

[@hussainbiology]

You're welcome!

[@lovelysharma3753]

Thank you so much

[@hussainbiology]

thanks Lovely for appreciation....Keep sharing and supporting

[@tanu6464]

😊😊😊😊😊😊😊Thanku

[@sunipamukherjee6064]

Sir I have a confusion .. Please make it clear ..... I read that MHC II remain inside ER of APC and after processing only Antigen and MHCII both express from cell membrane together ...So if SUPER ANTIGEN never enter into APC then how MHCII alone secrets from ER, come and express from plasma membrane??? If there is no antigen within the APC then MHCII shouldn't express from APC???

[@hussainbiology]

MHC II is processed in ER in association with Endosome., Do watch the video MHC II processing by Hussain

[@venkybly]

Tq

[@karkaspir2102]

God bless you

[@hussainbiology]

God bless u too

[@MiraiWaSora]

Thank you, may Allah bless you 👍🏻

[@hussainbiology]

thanks for appreciation..Glad it helps....✌️

[@hussainbiology]

Allah bless u too

[@hussainbiology]

Allah bless u too

[@grahamkelley8343]

THANks!

[@hussainbiology]

most welcome

[@bibekbastakoti5290]

Are you kashmiri??? The way you pronounced "against" I am preety much convinced that you must be Kashmiri.👍️

[@hussainbiology]

Indeed i am 😆... the Kashmiri Accent can be recognised anywhere in the world and u also got that ✌️

[@mmh3999]

Very good material. BUT, YOUR PRONUNCIATION IS OFF, For people who are not Indians. So, please slow down, and pronounce the words a little clearer! Thank you.

[@hussainbiology]

thanks for appreciation... and Surely i will consider working on Pronunciation

[@omarwani7476]

Great cricketer and also a great biologist! NICE INFO! KEEP UP!

[@hussainbiology]

Thanks buddy..... Appreciation from a Great Cricketer and also a great Doc.....

[@kuruvi2000]

Bai, is corona virus a super antigen?

[@piyuhart1719]

This was the easiest explanations everrrrrrr!!!!! Kudos❤❤❤❤❤

[@hussainbiology]

thanks for appreciation..Glad it helps....✌️

[@ughsirius]

THANK YOUUUUU

[@hussainbiology]

most welcome.. Keep sharing and supporting

[@elydayn4652]

It was very fast

[@musikaaffection8570]

Thank you soo much sir ✌️

[@hassanqamar7532]

ASSALAMUALAIKUM BROTHER

[@dibyajyoti7]

Thank you!!! Simplified

[@hussainbiology]

Thanks for appreciation..

[@rehanrahi4824]

Salam ya hussain

[@Micro-life]

Wowwww sir aftr long tym i got the topic tht i was searchng fo....thnk you so much😊😊😊

[@hussainbiology]

Actually i was lil busy , from past week otherwise i would have come up with ur request ASAP.....I hope u get learn from this

[@Micro-life]

Hussain Biology ......sir ur teachngs means a lot🙏

[@ManutheJKboy]

Bratati Paul ur request for this ..helps me 222

[@salehabegum8410]

Great job sir!

[@hussainbiology]

Thanks Saleha for appreciation....

[@connorbrady5115]

thank you. my stupid online module couldn't explain this and you helped a ton.

[@hussainbiology]

Thanks for appreciation..Glad to know that it helps ✌️

[@hassanqamar7532]

JAZAKALLAH khair

[@feliciapitts422]

This video was awesome! Thanks for the help!!!

[@hussainbiology]

Glad to know that it helps.. Thanks ✌️

[@mabuchikou2528]

Excellent explanation ... thank you❤

[@abdallamorsy]

thank you very mush for this wonderful illustiration ..my god wish from Egypt

[@hussainbiology]

Thanks Abdullah for appreciation...Glad to know that it helps...Allah bless u too

[@luvmysequoias]

Can Strep Group C cause this or similar reactions?

[@manjunathgoudanh3485]

Nice

[@hussainbiology]

thanks

[@SowmyaSwimInScience]

Very nice representation sir

[@Cookingwithrajat0926]

By what mechanism are bacterial superantigens thought to cause symptoms associated with food poisoning and toxic shock syndrome?

[@VaibhavDurgad]

I believe it's bcz of Non specific t cell activation

[@Donferish]

Thank you. Crystal clear

[@hussainbiology]

You are welcome..Keep sharing and supporting ✌️

[@jholokroy1412]

Bro...You're genius

[@hussainbiology]

thanks buddy

[@MonCherie9410]

Excellent explanation!! But I have one question. Besides those syndromes caused by excessive release of cytokine, will the superantigens be destroyed?

[@ananyaadr]

Thank you...really helpful

[@hussainbiology]

You are welcome...Glad to know that it helps ✌️

[@waseerahman3734]

Thank you, this was really helpful

[@hussainbiology]

thanks for appreciation.. Glad to know that it helps ✌️

[@navaneeth_us]

Beautifully crafted video. Thank you so much

[@marcfavell]

very good video 👍👍🍀🇨🇦🍻 sars2 has a lot of tricks up it's sleeve it seems !

[@hussainbiology]

thanks for appreciation..Glad it helps....✌️

[@amaypaulsingh1894]

Thanks sir!

[@hussainbiology]

Most wlcm

[@Aditya-sc6rk]

Bai u r the best

[@hussainbiology]

thanks Mr for appreciation

[@sbeeg98]

Super helpful! Thank you

[@gyanpelu001]

is it a kashmiri guy's voice?

[@hussainbiology]

Yes absolutely right...I am Kashmiri

[@sifarmeredith7146]

Excellent!

[@gyanpelu001]

great video sir. im from jammu

[@hussainbiology]

Glad to know that....... keep supporting 😊

[@ramchandrasuthar2848]

Very nice analysis

[@hussainbiology]

Thanks bro.....

[@tahirtantary7438]

Nice....superb

[@hussainbiology]

Thanks Tahir for appreciation.....Glad to know that it helps.....

[@DaFan86]

Excellent video, thank you.

[@hussainbiology]

Thanks for appreciation......

[@massinissa_math]

Thank you ❤️

[@satishdarlz7655]

Great work sir please do a complete series on immunology

[@hussainbiology]

Thanks Satish for Appreciation,,,,,,Surely i will be doing lot of Immunology videos, as i have already done a few in past too

[@satishdarlz7655]

Thank u sir

[@hussainbiology]

and i thank for ur feedback........continue supporting

[@tessnasri5716]

Well explained and so simple thanks ❤️

[@hussainbiology]

Thanks for appreciation...Glad to know that it helps.

[@aniruddhchandraker7531]

Very informative Video Sir

[@vasilis1963]

Simple explanation thanks!