Immune System

Explore the basics about the immune system with The Amoeba Sisters! This video talks about the three lines of defense and also compares cell-mediated response with the humoral response.
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Factual References:
Clark, M. A., Douglas, M., & Choi, J. (2018). Biology 2e. Houston, TX: Biology Stax. openstax.org/details/books/bi...
Reece, J. B., & Campbell, N. A. (2011). Campbell biology. Boston: Benjamin Cummings / Pearson.
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Further Reading Suggestions:
Discover many other types of white blood cells here! openstax.org/books/biology-2e...
More about antibody classes? openstax.org/books/biology-2e...
More detail about the cell-mediated and humoral response? openstax.org/books/biology-2e...
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The Amoeba Sisters videos demystify science with humor and relevance. The videos center on Pinky's certification and experience in teaching biology at the high school level. Amoeba Sisters videos only cover concepts that Pinky is certified to teach, and they focus on her specialty: secondary life science. Learn more about our videos here: www.amoebasisters.com/our-videos
Support Us? www.amoebasisters.com/support-us
Our Resources:
Biology Playlist: • Amoeba Sisters Biology...
GIFs: www.amoebasisters.com/gifs.html
Handouts: www.amoebasisters.com/handout...
Comics: www.amoebasisters.com/paramec...
Unlectured Series: www.amoebasisters.com/unlectured
Connect with us!
Website: www.AmoebaSisters.com
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MUSIC:
Our intro music designed and performed by Jeremiah Cheshire.
End music in this video is listed free to use/no attribution required from the KZbin audio library kzbin.info...
COMMUNITY:
We take pride in our AWESOME community, and we welcome feedback and discussion. However, please remember that this is an education channel. See KZbin's community guidelines and how KZbin handles comments that are reported by the community. We also reserve the right to remove comments.
TRANSLATIONS:
Thank you for those that have translated the subtitles!!
German subtitles translated by Laura Bilinson.
Romanian subtitles translated by Proseanchin Tudor-Ioan.
Indonesian subtitles translated by Hanifah Yumna.
Some translated subtitles on our videos were translated by the community using KZbin's community-contributed subtitle feature. After the feature was discontinued by KZbin, we have another option for submitting translated subtitles here: www.amoebasisters.com/pinkys-... We want to thank our amazing community for the generosity of their time in continuing to create translated subtitles. If you have a concern about community contributed contributions, please contact us.
We have an authorized channel with our videos dubbed in Spanish here
/ @amoebasistersespanol

[@alkiskarmpaliotis2776]

*_Two red blood cells met and fell in love. But alas, it was all in vein._*

[@respectthosewhodeserveit5192]

Alkis Karmpaliotis oof

[@sylviac02]

Romeo and Juliet who I only know red blood cell 1 and red blood cell 2.

[@slolilols]

Is that a cells at work reference??? Except it's not accurate 😂. Good pun though.

[@randomhuman4977]

@@slolilols yes indeed

[@elizabethdillard3998]

haha!

[@agbadudukevwe2471]

3 years later and the video is still saving lives of medical students. Thank you, guys!

[@enjayy09]

bruh im in 9th grade and need to know this😭

[@Sai36ofc]

@@enjayy09 Same!

[@Ladykaori14]

Bruh im in 7th grade and i need to know this​@enjayy09

[@arosmiertka]

You learn this in medical school? I'm a high school student and I have to know this already.

[@Ladykaori14]

@@arosmiertka I'm in 7th grade bro

[@walakongmagawalol1659]

im a medical student and whenever i need to understand concepts, i just watch your videos because it just makes so much sense from the analogies and their functions. Especially the illustrations make it more memorable. UR A LIFE SAVER

[@imakerandomvideoslol7499]

I KNOW RIGHT THEY'RE SO AMAZING !

[@eiantsou6109]

how's medical life going

[@eunwoovrs1715]

FRFRRR

[@Asaspecimenyesimextraoddinary]

How’s it going at med school? I got my final exam in 2 hours and I’m so screwed 💀

[@zavdielapolinariorosemilla3754]

Yeah I know amazing drawings. Actually these videos helped me pass my Science Exams

[@mariaadeel2423]

Damn the illustrators had fun making this.

[@AnasKhan-tf3vo]

Hellooo

[@Fumbersman]

*illustrator

[@silverstar1726]

Ye.

[@mateogaitan2371]

I'm pretty sure it's the purple one.

[@mwahbysxfaa]

Frr 😂

[@Daniel-nm2qb]

Are you kidding? You have such perfect timing! After break, we are going over this, and you're already ahead of time. Kudos to you! Thanks for everything you do. You help a lot of us out ;D

[@Connerboss2007]

not anymore

[@Daniel-nm2qb]

@@Connerboss2007 lol this did not age well.

[@allinavydal]

@@Daniel-nm2qb school started weeks ago... ...and im still online

[@ky0m1e]

@@manuraghubala you clearly don't know what that means.....

[@yousefzedan9306]

IKR these vids always come out when I need them.

[@reeeeeeeeeeeeeeeeeeeeeeee3235]

Now you have me thinking that there's a bunch of cells with bows in my body.

[@Khloe_dancer_model]

lol! I will imagine the same! They are cute!😂☝️❤️👏🏻

[@mwahbysxfaa]

Haha! Wish it was real 😝

[@BlueBird-wv7yr]

Every time I study biology, The faith in God increases "and has created each thing and determined it with [precise] determination" Quran

[@metialemayehu3514]

Nice perception

[@mwahbysxfaa]

Muslim also!

[@twomorestitchesleatherwork1527]

This was so educational, wow. Also the illustrations make it a blast to watch. Awesome work!

[@gamerprox2838]

Ever heard of kurtzgesagt?

[@BenMaleHealthCoach]

Right?!

[@jezzsouthern]

If this a blast to u I suggest watching paint dry absolute thrill

[@asifrahman60]

This was a great video, I'm planning to do an essay on the immune system and its complexity and this 7helps a lot

[@mwahbysxfaa]

​@@gamerprox2838wtf is that💀

[@hansvongruber3214]

Perfect release of a video during the COVID-19 pandemic

[@tmdrake]

POP!

[@ameliamizal5631]

Bloob yes

[@roselynruiz7339]

Yep

[@marcelopareja4976]

lol yep

[@mwahbysxfaa]

Yet saw this video at 2024😭

[@Tr1x527]

this is so entertaining I'm watching this in my own free time

[@Aarae77]

Peter Bui 💀

[@hummokaycool7536]

Same 🤣

[@HyruleChampionsUnite]

I watched Crash Corse Biology for FUN last night because I couldn't watch NOVA documentaries. I'm watching this for fun too.

[@love2learn-itsastorynotasu40]

OH. MY....STEM CELL. I saw the notification saying that this video is about the immune system, while I was working on the script for my own video!! I am soooo grateful that this video has been posted at this time, now I'll be able to research better!! Thank Amoeba Sisters, your science channel is the best and funniest out there I watch these instead of Netflix...... .....Maybe that is why I am a nerd who lives under a rock... Oh, who cares, I like it that way! Thanks again for the amazing content!!

[@ashrithachiguluri8872]

Haha

[@coco_cory]

Did you just say oh my stem cell.. 🤣

[@elliottstark5619]

When?

[@elliottstark5619]

@Rohan Krishnan stop the spread

[@mwahbysxfaa]

Lool! Nice way to say "oh my god" in a video thats all about cells❤😂

[@alexandremiseraph9946]

The first thing that came to my mind after watching this video was the manga/anime "Hataraku Saibou" (Cells at Work). Thanks for bringing back that memory, amoeba sisters!

[@AmoebaSisters]

Petunia absolutely loves that anime (and manga)! ≧◡≦

[@hanna_9505]

Rightttttttt the anime is one of my way to understand immune system chapter💞👍

[@WisteRia.s]

Me too! I saw this comment after posting mine. Lol! 😅😁 I absolutely love it!!

[@crazyboutferrets]

I have the manga 1 and 2!

[@alexandremiseraph9946]

@@AmoebaSisters Would you recommend it to other people?

[@ThatClinicalInstructor]

I'm a nursing & allied health instructor and I swear NOTHING makes me happier while distance teaching than Amoeba Sisters videos! 🥰😍🤩

[@mathewthomas6694]

I just realized that Amoeba Sisters hit 1 million subs. Congrats Amoeba Sisters!

[@bigturdgames9802]

Soon to be 2 million!

[@mwahbysxfaa]

2.05million now:( they gained a million in 3 years 😭 should've gotten more😢

[@Freeyourself206]

Can you do a video explaining the covid-19? That would be most excellent!!!

[@jomiliamoulton6578]

Its like flu but worse

[@jomiliamoulton6578]

So go to nucleus medical media

[@jomiliamoulton6578]

And type in flu

[@jomiliamoulton6578]

But think of it in a worse way with punomia

[@jomiliamoulton6578]

I am 11 so I am not that smart 😊lol☺

[@brittanybarr7592]

So, I'm a nursing student and my teacher actually showed us this video today while going over our immune system chapter and I am so GRATEFUL that she did! I remember better by seeing pictures I can put with what I'm learning and this is absolutely amazing for the way my brain works! I am so thankful she showed me this as I plan to follow and watch all the videos that pertain to what we are learning. I am so thankful for you guys!

[@vickydut132]

I’ve watched this video several times and each time I find the illustrations even funnier. I showed it to my nephew and he couldn’t stop laughing. Thank you for making learning so fun and easy. I owe the succession of my 2nd year of studies to you. 💕😂

[@allisonbuckles4943]

I needed a review of the immune system to begin to tackle my graduate level Pathophysiology class as I'm in Nurse Practitioner school. This was BEYOND helpful! Thank you so much!

[@sofihiley1116]

I have a test on this tomorrow and your videos are always what I come to to study. This could not have been more perfect timing! Thank you!!!!!

[@Dinonugetz_vr]

dont care

[@sahar2689]

I was just studying this topic for my exam when you uploaded this

[@hiraya3]

This channel helps me with studying for the college entrance exams, tysm!

[@hannahcamp7352]

icstnn_ , its so interisting right?

[@hello4872]

Honestly Who else was thinking about the corona before this

[@novadiscipulo5965]

Me

[@robersone7973]

Me

[@marcelopareja4976]

me lol

[@Connerboss2007]

me

[@vedantsingh2258]

me.....

[@brianfebles3113]

your videos are amazing, thank you for making our life easier.

[@jellyace2746]

"Protects you day and night" Me:OMYYY IM INLOVE WITH MY BODY

[@user-to7tq4jy8i]

I swear I did not understand this from my teacher but right now I understand it and can imagine it too 💜💜 Thank you alot 🥺 💜

[@yaseenbedair1713]

Your videos are a literal life saver. They explain everything in a informative and comedic way that makes it so much easier.

[@user-rx5cc9df8h]

This channel has such an amazing way of presenting the information so that anyone can understand. MUCH MUCH appreciated! Life savers!

[@mehulipoddar7114]

Such a fun and informative video! I am watching this before my biology exam, and am happy that the working of our immune system is explained so simply here.

[@prakashkonnur9736]

You guys are doing a great job,the idea of teaching us by animated videos is awesome.U made studying entertaining,stay blessed ❤

[@annaivanov9435]

Your videos are so far the only way I am understanding Biology right now. I am SO grateful for you!

[@chelseaibe3718]

Honestly your channel is soooooo underrated. ❤❤❤ you girls are one of the best

[@cms3482]

How? MY school was going to review this tomorrow. AKAK a midterm, and that's when I discovered this video. I mean y'all, how can this get any better

[@vidhusampath4022]

This was so interesting. I really liked the cytotoxic T - cells drawing.

[@kinzaawan6803]

I've covered this topic in high school, in first year uni, second year uni and so on... yet I always get mixed up one way or another. For the first time in my life, it just clicked! Thank you so much Amoeba Sisters! This was perfecto!

[@lauraallard2989]

I just came across this video as I was looking or a cool way to introduce this topic. I am LOVING this. As a nursing instructor- this is perfect. You all are amazing

[@filipaanastasova2084]

Honestly, your content and story telling method is absolutely fantastic ! Very inspiring 🤩

[@Dinonugetz_vr]

i dont remember asking

[@WisteRia.s]

So...I have my exam tomorrow and this a cute little video that has summed up everything in 8:55 😁 Thanks. I've never loved amoebas so much!!! (I wish my teacher was an amoeba😛)

[@DoYouKnowTheTruth]

I love how you used the animation to community a complex concept in a digestible manner. thank you!

[@alexialaurie7228]

This is amazing! We’ve just finished a chapter on the immune system in class I great detail, and this sums all the main ideas really really well! It’s super useful to link all the different response and get a global understanding of how the immune system works 👏👏👏i love your videos!!❤️❤️❤️❤️

[@Idodo680]

That. Was. So. COOL. I loved that you explained it in a way that didn’t involve words that nobody understands and then you’re loosing interest and you like forget it🤦🏽‍♂️. Amazing👏🏻

[@maijathrontveit6234]

I'm not even in Biology class anymore, but I just LOVE your videos! They're so funny and cute and educational! THANK YOU!!!

[@mariamelazab7994]

I am a first year nursing student and this video was so cute and helpful. Really simplifies things and helps to remember them. Thank you so much Amoeba sisters!

[@crystallane8379]

Thank you SO much for these fun, exciting and relatable lessons!!!

[@jameswood5357]

i just discovered your channel the other day, I love your videos! Biology isn't usually my subject of interest, but you guys make it really enjoyable :) All the best from the UK

[@sora2756]

I LOVE YOUR GUYS' WORK! I think this topic is really interesting too! Keep up the great work! 🤗

[@noemibartha7608]

i can not express how much i love your chanel. im so grateful that i found it.

[@lohendralevin8672]

When I got my biology book beside me,I need amoeba sisters to guide me. Thank you for everything.

[@sherenyossry4491]

This is an amazing lesson and funny too . You made me love the lesson and imagine these characters each time i talk about them🥰

[@lee_onyoutube]

I’m a psychology student and this is so helpful. Thank you, sisters!!

[@itsarsh.]

I'm a pre-med student preparing for medical entrance exam. this channel is my go to whenever i can't understand a topic. thank you, very well explained and the animations are a cherry on top.

[@julia50196]

Your guys videos make learning FUN and always have me excited to learn. Love this channel

[@pixiestixlush]

Ahhhh! I love this video! I already use so many of your videos while teaching and I have been waiting for one on the immune system. I teach microbiology, so of course we go into all of the details, but this is an excellent overview video on the big picture and the connections between innate and adaptive immunity. And IgE wizard antibody cracks me up.

[@Frenzee2]

I watch these all the time instead of watching netflix I watch these with my girlfriend

[@erynandersen8359]

Oh my gosh, these videos are so amazing! thank you, thank you. I am in college, and these videos explain what is going on SO much clearer than anything else I have come across. You guys are beautiful people

[@shenellsmith6849]

Omg i missed this channel ....😭 so glad your back!

[@carrot1c]

Cell Of Duty: Immunity Warfare.

[@calebwolbach325]

Lol

[@linc.5683]

garden warfare is no more

[@quanplo3298]

@@linc.5683 he/she mean call of duty but with cells and modern warfare but immunity

[@s_h_u_a_n]

Lmao

[@Ritzlyn]

For a person with autoimmune diseases, this video made me come to terms with my immune system, no mater how haywire it is now, it’s just trying to protect me. Now I’ll just imagine my immune “army” as these little guys portrayed in your animation. ❤

[@somedudefromapharmacy]

Hope it gets better for you man

[@tatianacolon2565]

does anyone else watch these and actually chuckle at the animations while simultaneously being entertained? thank you amoeba sisters, for somehow making cell membranes funny.

[@official_gd_sadd_2024_yt]

I Hope you do the one about What to know about COVID-19 (2019-Novel Coronavirus)

[@missprettyschannel]

0:31 I sneezed right on time lol talk about good timing😂😂😂

[@padmajabhavanichennupati6533]

You display such complicated topics in such easy and fun ways!

[@edwardhaughney9665]

You all are on the top of Mt Everest. Dont look down and keep going up. Thanks a lot.

[@sportsfails4998]

Macrophage: *sees 1000 coronaviruses* Macrophage: "I like the odds."

[@bernicematos708]

Congrats on being verified!!! BTW: I love love love your work!!

[@nadew.02]

This is wayy better than my immunology professor's course. Thank you so much

[@onyinyenkemchor-albert8757]

Can I just say I love how you talk... it feels like I’m getting entertained and learning at the same time... feels like story time 😌

[@jonatanmertimo9306]

This came out at the perfect time. I've got my biology (and my English!) matriculation exams in two weeks.

[@paranormalpandomness2703]

Jesus! I love how you teach us 😭💜

[@trailerpark690]

A brilliant piece of explanatory animation ! And humourous ( possibly humoral! ) too 👍🤣😄😄

[@AloofCanine]

This is the best and funniest animated immune system video I have watched so far. Thank you for the laughs!

[@mikewazowskigaming3029]

never seen cells being so happy

[@Biomeducated]

I would love to see this mashed up with Cells at Work! anime style! :D Amazing videos! Just discovered this channel!

[@navidhasan7246]

U don’t know how much I love this channel!

[@user-om8si3oj6o]

A 2nd-year Biomed student and a video like this is still so helpful........THANK YOU SO MUCH

[@justakshat6167]

Just finding something worth nd useful during lockdown n finally found that. . good job really ....

[@shokofakarimi839]

I love everything about your videos, your funny tone and voice, the cartoons and how they are characterised. You are always on my top of biology channels list. Thank you for your amazing videos. Hope you never stop making videos 😁💕

[@salmaelgammal5667]

I am in third secondary and immune system is one of the most important lessons I study and this video has helped me a lot .......Thanks Amoeba Sisters

[@jiminshighnote]

The illustrations help me so much especially in making sense of the information. It also helps me retain the information. Thank you so much for the video!

[@Beauty_Insight]

I love ur channep

[@abhayagrahari6402]

Tomorrow is my bio exam and I was thinking that I should have commented on your previous videos to explain this topic...then I saw this

[@warrenlehmkuhleii8472]

They just keep getting cutter, Look at the little cells, they are so cute!

[@prishavrinda2208]

like platelet chan :D cells at works reference sorry ;-;

[@alicjabaszkowska7584]

The cage at 8.01 made me laugh so hard haha Thanks for all those cool images in your videos which help a lot to memorize all the information!

[@user-oe9fj9xm3s]

When I was at my senior year in high school I enjoyed watching your videos for fun! And now I'm 3rd year in my pre-med course and your videos get me through the whole year🥹🩷

[@sdma6005]

OMG this was amazing! Thank you for doing an immune system vid. I’ve been waiting for this for so long (Immunology student here). I realize for the sake of brevity you didn’t mention the MHC but it’s SO cool. If you need a future video idea. I recommend making one about the Major Histocompatibility Complexes I & II 💕

[@annymus4502]

S DMA How is it like to study inmunity? It looks cool!

[@carolinetorres3299]

They also didn’t mention cytokines and interleukins, interferons, tumor necrosis factors ... they should make a video about what happens in the immune system when you get a Cytokine Storm

[@jocelynbenitez6914]

Do more body system videos please 😭 your videos have helped me get As in all my college level sciences

[@savannahfreeman9889]

I love the Amoeba Sisters! They are funny and very educational. They make learning fun!

[@fatimahyamani9241]

Your channel is such a great channel, I didn’t see something like your idea before. Keep going, I learned a lot from you 🤩👍

[@hansvongruber3214]

Hello Amoeba Sisters, your videos are pretty awesome and it shows an awesome work ethic and interesting concepts of biology/science in a simple way, keep on making the videos 👍👍

[@dogsarecute1570]

Oh my godddd I literally had a test about this yesterday and I had some trouble understanding it why couldn't it be 2 days later 😂😭 I love your videos :))

[@muhammadrebin945]

14 papers on one video ! amazing and very helpful thanks !

[@emmapintiliuc8028]

This video explains Memory T cells so easily, THANK YOU FOR SAVING MY GRADES

[@itstiena]

wow immune system became like a movie, easy to understand 😂

[@kennethm.pittjr.3775]

1:31 Traveling by foot😆😆😆😆😆😆😆😆 I get it best page ever

[@FoxerZ]

Thank you for the love of God. I don't pay very good attention to health because of how he teaches, it's really slow and I can't focus that long on one subject for literally the whole class without moving on and learning something else about the same thing. Luckily for me, there are people like you that exist and can explain 2 weeks' worth of material in 9 minutes with the same in-depth knowledge that has been taught to us.

[@laurads8856]

Thank you ! I have been waiting for an immune system video with your fab animations and now I'm still remote teaching this is perfect - you have made me a very happy biology teacher !

[@dudical111]

"I'M POLLEN! I'M JUST POLLEN!" As someone with a million random allergies, I totally feel this.

[@melirj]

I am 2nd year med student and I am always confused about which one is antibody and which one is antigen. I hope not to forget and be confused anymore ^ ^ Thanks for your very useful videos, it helps a lot ♡

[@Dinonugetz_vr]

didnt ask

[@melirj]

@@Dinonugetz_vr I didn't say to you. Don't be taken over.😉😉

[@emvIyxo]

I love you guys so much, you make learning fun & enjoyable to do!!

[@kk-1085]

All your videos are extremely helpful. They are just amazing !!!

[@sreedharshankar8092]

Hey, it is a great idea to pic the topics of immune system, and the video was really amazing, pls ameoba siss, continue this series , it is a really wonderful topic to work on

[@cerise_ow]

Cold virus: *sees third layer of defence* Also Cold virus: "Ok lets go the other way!"