mad scientists in movies: I will take over the world mad scientists in real life: I will make beer out of spiders
@greenaum3 жыл бұрын
Technically making spiders out of beer.
@tartanhandbag3 жыл бұрын
@@greenaum technically making something not very beer-like out of a yeast variant with spider DNA spliced into it
@Butter-Milk3 жыл бұрын
We have more realistic goals, then?
@morro5703 жыл бұрын
@@Butter-Milk who’s we you aren’t a mad scientist
@what9083 жыл бұрын
mado scientisto in animes: El Psy Congroo.
@jacob28024 жыл бұрын
Dude, I cant believe you're making this technology open source. I've been reading about the possibilities of harnessing spider silk since I was a dork in middle school, and remember thinking the guys making the spider goats were cool as hell. I really hope you manage to extract and polymerize silk from this.
@aserta4 жыл бұрын
Because he's one of the good guys, not subverting science for the highest bidder. He's one of those scientists that need crowdfunding the most, to keep him free of the likes of bigCorpo who'd put a life patent latch on it and shut it for good.
@davidbergmann89484 жыл бұрын
Haha yeah it's awesome, right? 🍄
@rihardsrozans69204 жыл бұрын
Right? I remember watching Ripley's believe it or not as a child and one of the guys featured there had made a really durable, strong suit out of bunch of materials including spider silk he milked out of actual spiders and since then I wondered about the possibilities of creating some super hero costume out of spider silk. It's truly wonderful that people are coming together to make education easily accesible and likely creating future scientists.
@garethbaus54714 жыл бұрын
Same here.
@suhanrahaman43424 жыл бұрын
Even though spider sill is a real good material it also get most of its strength through how the spider twists the silk together
@user-N204 жыл бұрын
No wonder Tony Stark looked so impressed when Peter said he manufactured his webbing all by himself.
@bladeoftheruinedking25434 жыл бұрын
Yes
@nams0ldier5843 жыл бұрын
Yes
@cringepuppetguy3 жыл бұрын
Yes
@duskycyberian72573 жыл бұрын
Yes
@jonathanshepherd64233 жыл бұрын
Yes
@zebbofrags494 Жыл бұрын
Sad to see this experiment hasn’t been taken any further in 3 years. This genuinely made me feel interested in science for the first time in my short 20 year life.
@thethoughtemporium Жыл бұрын
It's being worked on, but we're trying to commercialize it so can't share updates yet
@_dylansaeed11 ай бұрын
@@thethoughtemporiumthanks, I was wondering why it wasn’t being continued
@sasukekun19979 ай бұрын
This had made so damn happy. I thought this project was long forgotten
@Delapadation9 ай бұрын
@@thethoughtemporiumI would think that this would get funding fairly easily due to how strong spider silk is and the amazing utility we could get out of growable high strength building materials, and something I just thought of while watching the video explaining the structure, spider silk is a fabricy version of reinforced concrete.
@Yogaismehh8 ай бұрын
@@thethoughtemporiumlike a suburban superhero???
@davieuacho4 жыл бұрын
Me, not understanding anything but still enjoying it none the less: "Ah, shit, they can't print repetitive sequences, what a bummer dude"
@evangrimm17024 жыл бұрын
😭
@hardanalljr.31384 жыл бұрын
Yup I'm a total Chad ,don't understand shit but it's cool
@liviawong69284 жыл бұрын
@@hardanalljr.3138 Are you build as a Chad as well? Cause, cool.
@whatdamath4 жыл бұрын
dude...
@outofcontext7284 жыл бұрын
X2
@Krakburg4 жыл бұрын
love your videos
@chickenpotpieare3things4 жыл бұрын
Anton came out of the Solar System to check out this amazingness!!!
@GrantH26064 жыл бұрын
hello wonderful person
@pyrodamix47714 жыл бұрын
LOL
@cg22294 жыл бұрын
me laying in bed eating cheetos: ah yes of course biomineralization peptides
@ghostlydude64784 жыл бұрын
This is basically me trying to understand how kars survived falling into lava, but with *Spiders*
@aog17474 жыл бұрын
Hell yea😂😂😂
@xephyre69554 жыл бұрын
I dont even understand algebra let alone this. But the idea is interesting enough for me.
@v12984 жыл бұрын
I saw a post online about the iron snail a couple of days ago, so I'm basically an expert
@saki13334 жыл бұрын
@@v1298 yes xD
@joelswartzentruber95613 жыл бұрын
Instead of wet spinning, try electrospinning. It should give you aligned fibers instead of randomly oriented ones from wet spinning. You should be able to cut a section and twist the web fibers into actual thread that are theoretically aligned so you get better load sharing on each fiber.
@tatianatub4 жыл бұрын
"the plasmid has been shared on my github repo for that want to mess around with it" imagine saying that sentence to someone in genetic engineering 25 years ago
@otheraccount52524 жыл бұрын
well, we didn't have git back then
@ArnoldsKtm4 жыл бұрын
@@otheraccount5252 NO SHIT SHERLOCK
@recklesflam1ngo9684 жыл бұрын
@@otheraccount5252 wow really
@Josuh4 жыл бұрын
@@otheraccount5252 Really???? I thought github was like hundreds of years old omg thank you
@theawsomnessdude4 жыл бұрын
@@Josuh the whacky part is that this sentence might someday be true.
@lukasd.43894 жыл бұрын
"I've become quite competent at designing dna from scratch" Why does this sound so menacing. But dude, youre awesome
@0Clewi03 жыл бұрын
because of prions
@hunterbakko93063 жыл бұрын
I mean he's kinda playing God so yes it is menacing
@adventurer32883 жыл бұрын
You WHAT
@superchinmayplays3 жыл бұрын
i can now become spiderman
@wobblewokgaming6553 жыл бұрын
*He's becoming a Spider-Man villain*
@MagnusDangerMagnus4 жыл бұрын
30:15 I love that I live in the future. The idea that I share the world with a KZbin-vectored, open-source, melt-printable, github-published bio-kevlar makes me happier as an adult than ice-cream did as a child. Thank you.
@makarismaileadnan4 жыл бұрын
I really don't get what you're saying, but I'm happy that someone's happy in this world
@gavart45094 жыл бұрын
Makar Ismaile Adnan He’s happy that the creator of this video is so transparent with his process and so willing to share his results. Plus, the fact that this content is distributed for free.
@pacificxplorer4 жыл бұрын
This is really “the future” it’s the transitional period between the past and the future. Right now everything cutting edge is being discovered and all these cool products will most likely be widely available by the time we’re all dead or really old.
@samuelr.60463 жыл бұрын
Is it just me or is it crazy that they can Patten certain animal genes, that's absolutely some dystopian stuff right there.
@sparking023 Жыл бұрын
I have absolutely zero biochemistry background, but I somehow feel like I understood most of what you explained in this here video. Amazing work, and as a Spider-Man fan, I'm eager to know more about the possibilities of IRL webshooters
@Noflippingwaydude Жыл бұрын
Don’t worry once I have money I’ll make them
@the_undead11 ай бұрын
This part you probably already knew, but using IRL web shooters with absolutely be one of the most dangerous things you've ever done or did anyone could realistically ever do, but spider silk binded with carbon nano tubes. Could absolutely if made correctly hold the weight of multiple humans, I don't think you're doing Oh that the web shooter could do in a little canister. That's the size of your pinky but in especially designed flat pack tank that goes over your stomach, now we're talking. Because of how easy it would be to vary the properties of the silk when you produce it, depending on which particular strand of genes you use, everything you see Spider-Man doing with webs would be at least theoretically possible to do with at least a version of what is demonstrated in this video
@JoelCreates4 жыл бұрын
I'll be following the development closely since, you know, I'm something of a scientist myself...
@kenzima69344 жыл бұрын
Lmao when is the Hot Glue Web shooter swinging video coming up?
@ivoryas16964 жыл бұрын
Joel Creates I wanna say same, _but..._ I don't know calculus yet (among many _many_ other things that would likely leave me a bumbling fool in most any *_real_* lab) 😞.
@JoelCreates4 жыл бұрын
@@ivoryas1696 I was referencing the Spider-Man meme, since I recently built a hot glue web shooter. Technically I'm a musician...
@ivoryas16964 жыл бұрын
@Joel Creates Neato! I'll check it out. -Also, I'm somewhat of a musician myself!-
@norlavine4 жыл бұрын
Me too - my latest project is observing the time it takes to cook a '3 minute egg'.
@jadegreenleaf7814 жыл бұрын
Arachnologists for decades: "If only we could produce spider silk" Thought Emporium: "hold my spider beer."
@TheWretchedOwl4 жыл бұрын
Now I want a “hold my spider beer” shirt.
@omniscientbarebones4 жыл бұрын
Hold my Southern Black-Widow in Ethanol*
@ultrachad2894 жыл бұрын
O-O WHAT THE FUCK
@alba21624 жыл бұрын
I wonder what spider beer taste like
@trajectoryunown4 жыл бұрын
Spider Cider - Made with real spiders
@Nighthawkinlight4 жыл бұрын
Instant thumbs up. Been waiting for this one.
@-NGC-6302-4 жыл бұрын
Me too. Great videos from the both of you.
@jonapple23254 жыл бұрын
Are you okay
@JKTCGMV134 жыл бұрын
This comment prompted me to give the video an instant thumbs up
@PakleniVuk4 жыл бұрын
I will combine Yeast and Starlite and rule the World!
@stiepanholkien6054 жыл бұрын
Now he just needs little wrist siphons.
@VirtualGobllim478 ай бұрын
"It's [spiders] silk gene wasn't protected by any patents" you guys realize as well how nightmarish is this sentence?
@magicsasafras34144 ай бұрын
Yup
@carinhadoscomentarios43254 ай бұрын
Why?
@cooldud70714 ай бұрын
@@carinhadoscomentarios4325 nobody should own the right to naturally-occurring sequences of chemicals
@mikoajciemiega80184 ай бұрын
@@cooldud7071 big corpo preparing to sue every spider on earth
@bearox83022 ай бұрын
@@mikoajciemiega8018 Ohhh you little jumping spider you used my compound!? You are getting sued
@Shotgun_Gospel4 жыл бұрын
Guy who invented penicillin: "Patent? That's absurd. You wouldn't patent the sun, would you?" Biotech firms: "Spider silk? Oh that was us, we invented that. Ours".
@sontapaa11jokulainen943 жыл бұрын
Capitalism go brrrrr
@Hoshimaru573 жыл бұрын
If someone could patent the sun they would
@nucleartoaster013 жыл бұрын
Let's not encourage them
@nzoomed3 жыл бұрын
@@Hoshimaru57 its called nuclear fusion!
@nzoomed3 жыл бұрын
Can someone explain how anyone could hold a patent to a gene found in spiders to begin with?
@crackedemerald49304 жыл бұрын
*shakes yeast vigorously* "they're a bit of a diva ngl"
@nicholassoultanian54554 жыл бұрын
Someone give this guy a like a giant research fund. he deserves it.
@diamond4xe7344 жыл бұрын
IKR dis crap is insane
@minermortal19974 жыл бұрын
Where’s Oscorp when you need’em
@EmmaHopman4 жыл бұрын
Patreon
@fuckdeadfaces4 жыл бұрын
@@theunknowngamer5477 You know those movies are fake right lol
@fleurgymcheurgy92674 жыл бұрын
@@fuckdeadfaces for now...
@regulargreg2 жыл бұрын
I had a professor in college. This is the kind of project he was barking about in his often encouraged tangents during biopolymer class. Your project is like a customized and detailed exploration that goes well beyond what he could elaborate on in class. Thank you for peaking my interest!
@AppliedScience4 жыл бұрын
Wow, what an incredible project! Your dedication and perseverance is an inspiration!
@thethoughtemporium4 жыл бұрын
Thank you so much! Once I've got some fibers made, I'd be happy to send them over for you to play around with if you'd like
@KnowBigDeal4 жыл бұрын
Here's an idea: Electron Microscopy videos of all the mineralised silks!
@simonRTJ4 жыл бұрын
@@thethoughtemporium Maybe Ben could X-ray diffract image them, or run them through a mass-spec, or the Electron mic, or ALL THREE! amazing work, there should be a "KZbin science medal" or something.
@MrEtronic4 жыл бұрын
i think we are on the cusp of a revolution ... who needs elsevier , springer or iEEE these dudes together with a couple other sci-tubers are doing more cutting edge research than many well funded snob colleges.
@Srfingfreak4 жыл бұрын
@@thethoughtemporium Growing fibers is cool - But I would reccoment that you try mixing some into a Kombucha brew and make a SCOBY - you'll get nanocellulose tied to fibroin... it might be revolutionarily strong. Use weak/white tea if possible, and you can actually just use mineral supplements in sugar water for a "cleaner" SCOBY. Also, that way, the yeast/bacteria make the sheet for you, and you don't have to worry about the fiber weaving process.
@ElderSign324 жыл бұрын
it's insane that this is even possible. i feel like a caveman listening to this
@veeenjoyer244 жыл бұрын
advanced homeman
@ViktorVano3 жыл бұрын
I am a software developer, but I am totally amazed how advanced and well understood biochemistry is.
@instantnoodles86402 жыл бұрын
I am a teenager, but I am totally amazed how advanced and well understood biochemistry is.
@themblue82362 жыл бұрын
I am an idiot, but I am totally amazed how advanced and well understood biochemistry is.
@philcollinslover567052 жыл бұрын
@@themblue8236 lmaoo
@mastershooter642 жыл бұрын
I am a biomolecule, but I am totally amazed how advanced and well understood I am
@johndawson60572 жыл бұрын
@@mastershooter64 you win this thread
@ShDw-cc1bs3 жыл бұрын
So what is the current status of this project? Have you scaled up the process and/or have enough of a sample to play around with for a video demonstration? Would be incredibly interested in obtaining a sample of the yeast for a related personal project (involving kombucha SCOBY bacteria) if at all possible.
@TechIngredients4 жыл бұрын
As fellow You Tubers we continue to try to improve our content aware of the friendly "competition". You keep raising the bar...Damn Excellent video, keep it up!
@thethoughtemporium4 жыл бұрын
Thanks!!
@eatonkuntz4 жыл бұрын
hey Tech Ingredients I love your channel too
@VengeanceCore4 жыл бұрын
@@communist754 lol
@spambotbro8394 жыл бұрын
@@thethoughtemporium You should collab with NileRed
@bmxscape4 жыл бұрын
@@communist754 why would he collab with someone who no one knows xD he doesnt even know if you know anything about the topic
@kentvandervelden4 жыл бұрын
Pretty cool, and there's more power in presenting on KZbin instead at academic conferences.
@Barskor14 жыл бұрын
But my tenure!
@philanthropicnightmare12064 жыл бұрын
A lot more. Get ready for an influx of scientists making KZbin channels.
@icdeamons1124 жыл бұрын
'With great power, comes great responsibility.
@catwithagun9024 жыл бұрын
@@blackjoker2345 REALLY great profit margins
@nezgroul6664 жыл бұрын
As a molecular biologist, the explanations in this video are better than most of my uni courses. Difficult principles made simple. Explaining something so that someone uninitiated can understand is a gift. Kudos for the job well done, your countless hours spent on this project were not in vain, sir!
@TacetCat4 жыл бұрын
My mind is blown. I knew bioengineering was a field that existed, but had never *really* thought about it. When I watch a video on chemistry or physics, I usually get most of it. I understand enough about chemistry to usually follow along with whatever video I'm watching, even if it goes to the slightly more technical side of things. *This* video was 33 minutes of me going "wat." Okay, making yeast produce things. I've heard of that. Wait, you can just write DNA like you're a programmer? Wait, there are companies that will print DNA projects for you? This is common enough that a business can be made for it? Wait, you're taking a bunch of different genes and randomizing them and somehow you get the properties you want? Oh, silk sort of doubles back on itself for added strength; I get th- Wait, you can just add properties to it like it's a new spell in a video game? Wait... Suffice it to say, I think the remainder of my day is going to be spent learning as much as I can about this. Fascinating is too weak a word.
@neut11214 жыл бұрын
that's exactly what was going on in my mind watching this video
@HELL0RWIN4 жыл бұрын
Yep. I feel totally the same. I want to know more.
@TheMightyZwom4 жыл бұрын
Same here... just... wow...
@nikkoa.36394 жыл бұрын
You've found your resolve my friend.
@Someone-ig7we4 жыл бұрын
IKR it's like a game xD. You can just add whatever you want??? Lmao sign me up!
@wataruishihara15704 жыл бұрын
I’m just sitting here wondering how Peter Parker did all of this
@BRONZETOAST4 жыл бұрын
I'm wondering why I've been searching for a Spiderman comment. Thank you
@lordofhnajuty4 жыл бұрын
Same as tony, with a box of scraps but in a slightly nicer apartment.
@brdiejustvibin1434 жыл бұрын
did it in high school too ..,like how
@EthanbloxBiggestFan4 жыл бұрын
The excuse is that Peter feels the necessity of making spider silk so that’s why he can make it? It’s really weird if I’m honest
@gavinhicks76214 жыл бұрын
Well Toby McGuire his webs were natural Andrew Garfields were stolen from oscorp and Tom Holland I don’t know but I’m pretty sure in the comics (I’ve never read them so this might be wrong) the spider bite gave him the formula composition and he was able to buy the products to make it
@TheMysticGauntlet4 жыл бұрын
Peter Parker : No one can figure out my super secret spider web recipe. The Thought Emporium : Hold my beer.
@uxleumas4 жыл бұрын
isn't all beer made out of yeast though?
@bovanshi65644 жыл бұрын
Hold my spider beer*
@pete84204 жыл бұрын
Hold my test tubes
@TheMysticGauntlet4 жыл бұрын
@@bovanshi6564 Spiderbeer Spiderbeer... Does everything a spider can... Make a web? Anytime... Look out... Here comes the Spiderbeer...
@SquaredSmith4 жыл бұрын
Hold my beer but don't drink it. It's full of spider silk and tastes terrible.
@samdwichenjoyer2 жыл бұрын
Rewatching this video a second time and chuckled thinking about how people used to think everything was made of air, water, fire, and earth, and here you are doing this sorcery
@reedbrooks38874 жыл бұрын
Spiders: You will never be able to farm our silk... Humans: Ok, we’ll just steal your genes and put them in other organisms.
@Salt_discriminater4 жыл бұрын
Hippity hoppity your genes are my property
@nightelfmohawk98214 жыл бұрын
Surely nothing can go wrong when mankind tampers with nature... GMO is scary stuff
@fred_e4 жыл бұрын
@@nightelfmohawk9821 Well, I mean, spiders are scary too, I guess.
@fred_e4 жыл бұрын
@@nightelfmohawk9821 And chihuahuas
@lolgamez91714 жыл бұрын
@@nightelfmohawk9821 k but, how is farming spider silk dangerous
@kastiak064 жыл бұрын
"New merch coming soon! Who wants some homegrown T-shirt?!"
@billeethesciencegeek4 жыл бұрын
"I love it so much, I can't seem to take it off!"
@GuilhermeCargnelutti4 жыл бұрын
The yellow ones are edible, but don't try the blue ones
@Scott_C4 жыл бұрын
Only $9,999.00. 😄🤑
@pablozurita29964 жыл бұрын
@@GuilhermeCargnelutti I'm gonna eat the blue one
@tryplot4 жыл бұрын
the colors wouldn't even need to be dyed. they could actually be from the silk it's self
@ShamelessDuck4 жыл бұрын
I can't imagine I live in the time when THIS is possible. You are in my "God-Tier KZbinrs" list
@tormodhag68244 жыл бұрын
ShamelessDuck like you can print DNA?! that is kinda crazy, just humans writing their very own DNA designed specifically to hijack in this example yeast. I searched DNA printing on google and you can apparently make custom creatures with it, which is insane
@ShamelessDuck4 жыл бұрын
@@tormodhag6824 I dream of future when we will use GMOs legally in our everyday life without it being marketed as "non-GMO" and without this whole stigma around it.
@puppypi96684 жыл бұрын
Ikr And I love how the God-Tier KZbinrs all know each other XD Applied-"I built a scanning electron microscope from scratch in my shop"-Science and Tech-"I made a nanostructure imprinted chocolate bar diffraction grating"-Ingredients both commented here alongside us! XD
@MaleniaLiАй бұрын
It’s crazy going from “wow that’s pretty cool, no idea how you did that, but it’s cool” when watching science KZbin to “huh, I did something similar in class last week, cool!”
@transformerslov4 жыл бұрын
Its so weird. He makes me feel like I can understand everything he is saying but at the same time I'm like 👁👄👁 okay 👍
@mechadonia4 жыл бұрын
4 mins in “what is he even talking about” 20 mins in “of course the pPCI9k needs to be linearized with a restriction enzyme! You can’t have those DNA rings, duh!!!”
@auve0G3 жыл бұрын
it sounds like foreign language
@nateracing3 жыл бұрын
I interpreted this as an informal video-essay type of report on his findings, truly fascinating, yet extremely confusing to people without bio-majors, like me ;)
@Hlebuw3k4 жыл бұрын
"I was able to purchase a whole vile of nightmare fuel for a grand total of 15 dollars" I did not need to know the price of an arachnophob's sanity.
@minermortal19974 жыл бұрын
Secret Santa gone hardcore
@knctvrknctvr4 жыл бұрын
@@minermortal1997 now THATS what I call an office party!
@natorious3143 жыл бұрын
I can't express how much I love that you document all this content for us to watch. Science in all fields can be so interesting, but it's so insular and stuck in the world of papers and journals that the average citizen will never hear about all the cool shit going on. You and many other science youtubers are really doing a great service.
@3asianassassin3 жыл бұрын
It's often that insularity that convinces people to take up and believe pseudoscience and eventually erode trust in science and data
@tbs00003 жыл бұрын
You call fax I mean we are all forced so deep into the thought that science is all boring stuff on paper but no it's fun aswell like artificial meat or aerogel and theories like our universe isn't finite and it's a loop from one point to another or that aerogel can be used in rockets as insulators.
@assfuckerthejointpounder58342 жыл бұрын
I remember how in the action lab they mentioned that the structural strength of steel regarding tensile strength is in the gigapascals. Even specialized steel it's not like it's 10,000 times which spider silk can handle or whatever. Who knows how many creatures have a shell made out of nacre oh, it's tensile strength depending on the species is 170 gigapascals, even if one gigapascal is 2 megapascals this is still a whole lot more than steel. The trouble is this bad boy takes 170 gigapascals to bend, or is that bend it to a point that it will no longer Bend back. Either way that is a whole lot. I did the conversion for both of those, 170 gigapascals is more than 24 million pounds per square inch, and 70 is more than ten million. I did the conversion for both, I checked the conversion multiple times for the tensile strength. I'm pretty sure that I did the 70 kg pascals correctly given how much of it was copying and pasting, and using an online calculator. This is far beyond Steel. Now this is so strong because of the way that it is aligned, according to Google it's like more than 300 or something times stronger than the material it's made out of. So imagine graphene was in the structure that this material is in. And I'm not talking about the structure of which its atoms are aligned. This bad boy is made in a structure of pretty much interlocking tiles, so imagine this was what was going on with a flat thing of the functionally two-dimensional graphene oh, that bad boy would be incredible however graphene is very flexible so this might defeat the purpose. However something tells me that if the graphene were to be bio mineralized to be interwoven with the nacre be beneficial.
@darkestwilightt3 жыл бұрын
23:42 "Thing number one.... be gentle with the yeast...." I just love the way he said that
@acompletelynormalhuman63924 жыл бұрын
Congratulations I know you've been working on this project for a while and it's really exciting to see you succeed
@Ryan6.0224 жыл бұрын
Spidey yeast Spidey yeast Produces proteins a spider can Makes a fiber any size, matches kevlar any time Look out here comes the spider yeast Is it strong? Listen bud,he's got enhanced gene strands. Can it be made into a thread? Take a look over head. Hey there goes the spider yeast!
@Froyorionpop11 ай бұрын
Nice
@crookeddesk4 жыл бұрын
"I've become quite competent at designing DNA from scratch" "and just have a company PRINT the DNA" Jesus christ watching your videos always makes me awe at the times we live in...
@kingbroseph97734 жыл бұрын
wait till he can print his own DNA without a company
@Jeff-ti4pd2 жыл бұрын
Man im so happy for you! I watched the first video a couple years ago and I was very anticipating the final and finished product! Congratulations on figuring it out and getting it to work!
@aflyingpumpkin10734 жыл бұрын
This was the fastest I have ever clicked on a notification.
@Dudeinatube4 жыл бұрын
Same
@nikolaytekuchev1364 жыл бұрын
First- Oh fuck
@foolwise47034 жыл бұрын
Dito
@ONNE7914 жыл бұрын
Right lol
@venus10514 жыл бұрын
I'm an art student but I'm sitting here, 5:15 pm, watching a man make spider's silk out of yeast. This is the coolest shit I've seen all day dude. Can't wait to see what you come up with next. Love the mad science bro.
@Gennys4 жыл бұрын
Someone needs to explain to me how any natural, unmodified living organism can have patents put on their genes in the first place...
@btw10954 жыл бұрын
Brian thats what we get in a a country run by corporations
@ahtheh4 жыл бұрын
Huh I've been learning that sht to get marks from the 9th Grade and now I can use that knowledge to brag to a random guy on the internet because I know it and he doesn't [I now realize that's all that information is every going to be useful for]
@senjugold69774 жыл бұрын
Lmao imagine existing and the big companies are like: "your genes are mine!"
@Larantula4 жыл бұрын
Kinda reminds me of the tree that legally owns both itself and the land around it.
@onidaaitsubasa41774 жыл бұрын
I know right, it seems that there would be some legal trouble with whoever made the patent and the original genetic designer of the animals, or would the actual spider be the patent holder of the silk since it originally created it, either way it doesn't exactly seem legal.
@BeaChapman Жыл бұрын
I still can't believe people can write DNA in Google docs. I hope to do that someday.
@StudioSkiesAndWater Жыл бұрын
Remember what he said tho
@PauloOlveira3 жыл бұрын
Just leaving this out here: A silk/graphene composite generating yeast that survives high salinity would be prime candidate for regenerating tidal turbines
@ninjanyan1579 Жыл бұрын
I understood all of those words separately and am proud of myself for that.
@ThisLockIsJammed Жыл бұрын
If this is true, on top of making it a commercial clothing or building material, this guy could be looking at a Nobel.
@wedmunds Жыл бұрын
I think that could do a lot more than just repairing turbines
@thecallankids4718 Жыл бұрын
While it could do that, would it not also coat the ocean floor in carbon doped silk?
@Gigan--a11 ай бұрын
@@thecallankids4718that I’d assume degrades faster than thousands of years
@legendarysideburns22134 жыл бұрын
Next project: yeast that makes spiders
@sleezymechanic4 жыл бұрын
Next next project: spiders that make beer
@notajalapeno44424 жыл бұрын
@@sleezymechanic next next next project:yeast that makes dimonds
@cg_pizza4 жыл бұрын
@@notajalapeno4442 next next next next project: yeast that make any material
@NewsChannel-y4g4 жыл бұрын
next project: watch youtube and feel like I have done something
@NewsChannel-y4g4 жыл бұрын
next project: clean kitchen
@colby38963 жыл бұрын
I’m actually amazed at how much of your research I understood as a freshman biochem major. Stuff like this makes me hopeful that I could potentially make a career out of genetics because before college, I really doubted my ability to be successful in the field
@jadenmead19283 жыл бұрын
never doubt yourself ;)
@ninjadel23 жыл бұрын
As a recent physiology grad this makes me hopeful to one day start working on unique avenues of research as well
@dgs_susave13242 жыл бұрын
Keep going. Who knows. You may pull a TASM again with the genetic spider 😂don’t give up on your dreams‼️
@assfuckerthejointpounder58342 жыл бұрын
Well if you want to make something like Godzilla be realistic then try using biomineralization to put nacre in its bones and scales oh, you probably want pockets of stuff like methane in there, methane is a gas produced by living things the most common example that not many people might necessarily know has it in there is when you fart. But farting is made by the methane or swallowed air, by making it have nacre the bones would take literally millions of pounds to not only Pull-A-Part but also Bend, or is that bend it to a point that it will no longer be able to bend back to its original shape. The tensile strength is 170 gigapascal, there are 70 for its strength for the bending thing. 170 gigapascals after I checked my conversion this correctly comes out to more than 24 million pounds per square inch, even if you use the metric system that is obviously a very high amount. The action lab which is a another Dependable source of science information said that steel is generally in the megapascal range, it takes a lot of megapascals to make a single gigapascal. And if its skin is made out of graphene, or whatever term is used for the soft flexible stuff that is what is responsible for holding the scales together on the skin of a snake or lizard. That bad boy would be very durable, for context just some graphene that is the size of Saran Wrap would require Force equivalent to a fully grown male African elephant balancing on a pencil. Not to mention that the Wonder material is also a very effective superconductor so you could probably use this to get rid of the issue of the Godzilla that is more than 100 m tall taking more than a second for anyting to register in its brain because the electricity take so long to move through the body. This graphene could eliminate that issue oh, so we could react without needing to be 15 M tall at maximum. And if it's hunched over like your average T-rex or Utahraptor this could help with blood flow at such a gargantuan scale. And if you argue that it doesn't have enough energy from the atmosphere to oxygenate it, there is an organism that can survive without any oxygen, also considering out at our degraded can literally live for multiple days in the vacuum of space. Something tells me there's probably the required already existing genetics somewhere in the world to let something survive at such a gargantuan scale. But maybe not after all a hundred meters is a very high number for the size of an organism on Earth.
@Ideas7952 жыл бұрын
Nice👍 I plan on majoring in biochem
@patrickhayes3099 Жыл бұрын
Glad to see this! 40 years ago I walked through a black widow web and began wondering about how to harvest the silk to make fabric.
@ramabary4 жыл бұрын
Make the web cure faster is hard enough. Let alone: 1. It can carry the man size weight 2. Produce a length of string 3. Infinite strings.
@sonofanutcracker42074 жыл бұрын
4. Become spiderman
@darknobz35603 жыл бұрын
@@sonofanutcracker4207 5. Great responsibility
@urtooslow44153 жыл бұрын
@@darknobz3560 great stress and late rent debt
@benbruder3 жыл бұрын
@@urtooslow4415 7. *MENACE!!!!*
@praddhyumnmani79253 жыл бұрын
@@benbruder 8. Get forgotten by everyone
@booker...4 жыл бұрын
Haha that spiders pretty hot amiright guys
@BitterTast34 жыл бұрын
Can't wait for the video on "spidey-sense".
@0th_Law4 жыл бұрын
@@BitterTast3 The real question: how would you go about achieving it?
@bleachisgoodforu93414 жыл бұрын
Get bit by every spider
@LOOTS2434 жыл бұрын
Spiderboiii
@ViktorTheMusician4 жыл бұрын
@@0th_Law Tarantula DNA? They use their hair to detect changes in the air. Spidey Sense was meant more to represent an invisible web of sorts, though I've also seen it as representing the 8 eyes spiders have though they actually have really bad eyesight. But by coincidence Tarantulas already have a spidey sense going for them.
@ziggiey4 жыл бұрын
All i can imagine is him looking at the genetic code and going "mmmm, silky"
@fionafiona11464 жыл бұрын
so smooth
@vasudevraghav21094 жыл бұрын
There's something silky going on......
@harrisoncord36803 жыл бұрын
make a web shooter and only if the silk was strong enough, you could be spiderman.
@Blaze22F4 жыл бұрын
*28:05** this moment left a big smile on my face* *Congrats my guy*
@defectivetoaster77134 жыл бұрын
Everyone here who has no clue what you’re saying just going along like “ah yes the graphene binding peptides have worked”
@0th_Law4 жыл бұрын
It's actually decently intuitive. If the yeast produces a protein with the ability to bind graphene, then the graphene oxide will naturally coagulate around the proteins, and therefore the yeast, because it is being bound to the proteins.
@TheIdiotFr01024 жыл бұрын
@@0th_Law hUh 😐
@0th_Law4 жыл бұрын
@@TheIdiotFr0102 If you want, I can clarify stuff for you; just tell me what doesn't make sense. (This is assuming that you mean that what I wrote didn't make sense. If that isn't the case, then never mind.)
@TheIdiotFr01024 жыл бұрын
@@0th_Law you said some smart stuff but I think this comment is meant to be a joke and you added some smart stuff to it, so idk
@0th_Law4 жыл бұрын
@@arrowsaurus7561 You're going to have to be more specific than that. Otherwise, the answer will probably just be something like "Cell Signaling" or "Conformational Changes"
@bumpket4 жыл бұрын
The dislikes are just the other spiders being jealous about this amazing silk.
@greengreen1104 жыл бұрын
And the big corps geting mad because the plasmid is open source
@VirtualGobllim478 ай бұрын
The FACT this all evolved through eons of probability is astounding
@nerobaal665515 күн бұрын
This has progressed my work farther and faster than I was hoping for. I appreciate your work and I thank you.
@KiJ0_04 жыл бұрын
Spider-Man’s web fluid is now becoming a reality
@zmalque4 жыл бұрын
FAVIAX Delatorre hol up
@alejandrobernal49874 жыл бұрын
Indeed it is, my friend
@Josuh4 жыл бұрын
@FAVIAX Delatorre 😤😤😤ಠ‿ಠ
@nikkiofthevalley4 жыл бұрын
@FAVIAX Delatorre That's f**ked up.
@KiJ0_04 жыл бұрын
FAVIAX Delatorre get out.
@giacomoarturogrelli89043 жыл бұрын
This is huge, it's amazing how you managed to succeed, this sounds like science fiction and yet you made it reality, I admire you
@ganf4 жыл бұрын
23:07 Stuff like this is why I love the internet. It's so nice to see researchers come together and help each other out :)
@trkoo2 жыл бұрын
What happened to this project? Can we get an update?
@LizardWizard10053 жыл бұрын
"A whole vial of nightmare fuel" I've never heard that be so damn accurate
@BahhBahhBrownSheep11 ай бұрын
I’m pretty sure that’s a statement you’ve never heard before, or in the two years since. So that’s not particularly impressive
@passingrando645710 ай бұрын
@@BahhBahhBrownSheepCounterpoint: the Pony Jar Project exists.
@Palitato4 жыл бұрын
"I couldn't isolate the DNA, so I just made it myself."
@davidmella11744 жыл бұрын
...
@aferrone924 жыл бұрын
I literally lost it when he said that
@ProctasisLimerna4 жыл бұрын
I will make my own DNA with hookers and blackjack
@Lucas-iSL4 жыл бұрын
@@ProctasisLimerna and without the N.A.T.O!
@minermortal19974 жыл бұрын
@@ProctasisLimerna this sounds like a Cave Johnson quote.
@kingarthurthe5th4 жыл бұрын
Giving a whole new meaning to “silky smooth beer”
@blueechodragon997 ай бұрын
11:00 thanks to high school biology, I can actually understand this. Thanks for showing a interesting use for the stuff we are learning!
@altofmoleperson4 жыл бұрын
Why am I watching this, my experience with biology is “the mitochondria is the powerhouse of the cell” and “sometimes, plants eat the sun.”
@imcoolerthanallofyou77514 жыл бұрын
I’m imagining a plant just biting a giant chunk out of the sun
@altofmoleperson4 жыл бұрын
@@joshuanetanel9174 Of course, the kale kills.
@Grumpy_old_Boot4 жыл бұрын
Soylent green is people too.
@patricknkwo6524 жыл бұрын
lol, same, I'm just curious to see what emerges in the next 25 years from him & this field
@hahayoucantstopmehawokenha40594 жыл бұрын
i would love to see a plant eating the sun
@user-N204 жыл бұрын
All the people who want to be Spiderman: *_confused but encouraged_* "Write that down! Write that down!"
@jameskelly92773 жыл бұрын
Lmaooo why would you call me out like this!!
@nightastheold90943 жыл бұрын
Lol I was in 7th grade and the 2002 Spider-Man came out. My friend and I thought we could make web shooters from aluminum cans and webbing from kitchen spices and cleaners.
@alionicle3 жыл бұрын
Aight, that's me right now
@Eatmywalnutz3 жыл бұрын
I want to make a web shooter
@kete66402 жыл бұрын
Ive been tryna figuring out how to be spider man for the past 3 yrs lol, and I DIDN’T RUN A SINGLE TEST BECAUSE 12 YR OLDS CAN’T GET A HOLD OF NYLON 6, 10 SILICONE AND ADHESIVE GEL. I ALSO WANTED TO ADD HIS SPIDER SILK LIQUID THING BUT I’M TO “UN-INTELLIGENT” TO MAKE IT. AND DON’T ASK WHY I’M YELLING BECAUSE IDK
@tinnfinn72934 жыл бұрын
Everyone watching this that has no idea what he’s saying: “You know, I’m something of a scientist myself.”
@estebancino54264 жыл бұрын
¿Is that that a Raimi reference?
@cleosvoyage3 жыл бұрын
@@estebancino5426 no.
@nicholass56213 жыл бұрын
@@cleosvoyage yes - the quote is from sam raimi's spiderman movies
@ytshorts96093 жыл бұрын
I studied abt genetic engineering
@DamianDeEu3 жыл бұрын
@@ytshorts9609 I studied the entire ABC of English alphabet and got it all memorised now! Pretty cool, huh? 😎
@daviddrift7663 Жыл бұрын
As you were talking, I thought about the book, Blood Music, by Greg Bear. Then I realised that you are indeed Virgil. Scary.
@baldiesss4 жыл бұрын
Type of guy to clone himself and go on vacation and we won't notice
@Snailcrossing4 жыл бұрын
KRIEGER!
@Z31HoodMoments4 жыл бұрын
“Was able to purchase a whole vile of nightmare fuel”
@nikkiofthevalley4 жыл бұрын
Lol, he's not wrong.
@nutsandbolts12644 жыл бұрын
This guy: *invents yeast spider silk* Everybody: SPIDERMAN SPIDERMAN DOES WHATEVER A SPIDER CAN
@erumaaro60604 жыл бұрын
it does add another meaning to "spider can", right?
@kiriki45584 жыл бұрын
Yeah, i was especting that. But i'm more interested in the practical use of spider silk, cause it's resistance is legendary.
@erumaaro60604 жыл бұрын
@@kiriki4558 I was referring to a Beer-CAN full of silk. (assuming you are replying to my comment that is) The practical applications are a no brainer. 10 years ago i would have shelved this under sci-fi, jet here you are actually doing it. btw, the biomineralisation feature sounds amazing. I cant even imagine what properties spider silk bonded to carbon nanotubes would have, but i'm sure it would get you out of a sticky situation, or create them for that matter.
@JeskaDax2 жыл бұрын
Been following your progress on this for so long. It's awesome to hear you're over that major hurdle! I look forward to hearing how the rest of your experiments go!
@Funlifedoga4 жыл бұрын
We have been waiting for this for sooo long!!!
@pvc9884 жыл бұрын
"First, its silk gene wasn't protected by any patents…" Wait, WUT?
@Plotatothewondercat4 жыл бұрын
The first entity to isolate a particular gene gets to file a patent on it under the current biotech regs. Leads to some very undesirable possibilities. It's one reason to be suspicious of those 'we'll analyze your DNA to determine your ancestry/risks' things, because it's potentially a mechanism for someone to gain a monopoly on all commercial use of one of your genes for the next few decades.
@wacesferpit4 жыл бұрын
capitalism
@Plotatothewondercat4 жыл бұрын
@@wacesferpit That's the more succinct explanation yeah.
@eichenbrain61704 жыл бұрын
@@Plotatothewondercat ... and then (after the 20 years) your own personal gene is open to the public to use as they see fit.
@Plotatothewondercat4 жыл бұрын
@@eichenbrain6170 Twenty years after a corporation had the opportunity to raise the price of whatever treatment it may have turned out to be useful for to the point that thousands of potential beneficiaries went past the point of no return without ever having the capability to pay for the treatment.
@GGShinobi774 жыл бұрын
What I also learned: The Web Shooters that Spider-Man uses wouldn't quite work just like that as it's shown in the comics... They would need to produce different kinds of silk depending on the use case... but he always just presses the same button. Still pretty cool though.
@ikathesquid09214 жыл бұрын
newer media of spiderman actually expand upon this by showing that he controls what kind of silk that comes out via tech in his web shooters. like from homecoming when veronica asks him what kind of webbing he wants
@ikathesquid09214 жыл бұрын
@@arrowsaurus7561 my bad lmao
@ikathesquid09214 жыл бұрын
@@arrowsaurus7561 mixed up hulk buster ai with Pete's
@AK-Drakoin4 жыл бұрын
@Dan Public ……You- by the original version you seem to be implying the Sam Raimi Spider man movies. Which was based on the comics.. The original comics where Spider man used web shooters and couldn’t have webbing organically. Ie. No The first movies were not the original version of Spider man
@AK-Drakoin4 жыл бұрын
@Dan Public oh no sir I am very sorry! I am sorry for my condescendence and I didn’t mean you any disrespect! I respect the fact that you hold the original films to such a high regard and liked Spidey so much! I completely understand, I merely thought you were someone who held the original comics to no meaning- in where Spidey originally developed his own web shooters (The original films probably decided to have it come out of him for screen time, and because a few other comics later on did have him have that ability) I’ll be honest, I thought you were an ignorant nerd 😝 and didn’t realize the whole state of the matter. You shouldn’t have to remove your comment because of my own condescendence. I wish you the best during 2020 sir! And I hope you live a good life 🙂
@levicearbhall6519 ай бұрын
Spiders: Look what they need to mimic a fraction of our power.
@shasni6264 жыл бұрын
"First: It's silk gene wasn't protected by any patents" whoa whoa whoa, hold on, what? What kind of cyberpunk is this?
@herrpez4 жыл бұрын
I'm cool with that. Assuming the spiders are the patent holders. But that strikes me as being somewhat unlikely.
@SomethingSmellsMichy4 жыл бұрын
@@herrpez spider lawyer
@datboii28774 жыл бұрын
@@SomethingSmellsMichy HAHAHAHAHHAHAH Spider Lawyer, Spider Lawyer, does whatever a lawyer does, does he defend? Yes he does, he can also climb the laws, watch out here comes Spider Lawyer!
@GIRGHGH4 жыл бұрын
This whole thing seems almost like a no-brainer in hindsight, dang this is cutting edge.
@culinarycow31814 жыл бұрын
The term is bleeding edge
@GIRGHGH4 жыл бұрын
@@culinarycow3181 I've heard it both ways. Just used the first that came to mind. There are surprisingly many ways to say the same thing sometimes :]
@culinarycow31814 жыл бұрын
@@GIRGHGH bleeding edge refers to thd science as it com out and cutting edge is the newest available technology available to scientists/ what ever specialist is in each feaild
@culinarycow31814 жыл бұрын
@@GIRGHGH just for future reference
@GIRGHGH4 жыл бұрын
@@culinarycow3181 I'm pretty sure the context is what determines if it's for research or technology, not which word you put in front of edge.
@darth_dan88864 жыл бұрын
This is literally the forefront of today's science. I don't believe anyone has come this close. Most researchers: OK, so we grew the spider silk, now how do we add additional elements to it?... Justin: screw it, let's add a gene that binds Calcium, Silver, and Graphene for good measure.
@FSantora Жыл бұрын
I can't believe you were able to explain this in a way I almost completely understand! I learned SO MUCH from this!
@FSantora Жыл бұрын
I would be interested in where LOTUS silk falls on the graph at 10:10
@choovick4 жыл бұрын
I have 0 biology and chemistry skills, but I love to see similar concepts and ingenuity you can find in many engineering fields! This is amazing!
@TwistedHound143 жыл бұрын
I honestly didn't understand what you were talking about. But I was intrigued the entire time. I didn't even know it was possible to PRINT DNA. This is some crazy stuff
@kamilag27914 жыл бұрын
I literally wrote about you in my university application. You're the reason I'm going to university. Thank you for creating videos and making them high quality and interesting!
@alexs81826 күн бұрын
This is very cool, but why there is no follow up video where you actually make silk fibers with this tech?
@TheDro3 жыл бұрын
I have a few bugs as pets as well, if you ever need anything lmk!
@jacobmate15373 жыл бұрын
gay cringe
@Retrobloo3 жыл бұрын
@@jacobmate1537 what
@7pagemuda9713 жыл бұрын
gay cringe
@Traveler_2023 жыл бұрын
Verified with only 3 comments? What
@cherieisdeadinside3 жыл бұрын
@@jacobmate1537 no u
@asmolbean93004 жыл бұрын
Biology brain me: ah yes an excellent video, a true breakthrough, very exciting. Normal brain me: hehe pretty colours
@shortkinga11Da44 жыл бұрын
Everyone’s talking about him using big words. Me thinking how he could be the next Spider-Man
@dragonmania17494 жыл бұрын
"Could be used for -coughs and shows picture of spiderman- s p e c i f i c uses"
@colonelh18754 жыл бұрын
I'm thinking about spider kevlar
@noodlesgamebox59033 жыл бұрын
They might not all SAY it, but we were all at least thinking it.
@Tom-ku8bu3 жыл бұрын
I think in the Korean war they used spider silk for an bullet proof vest. But nowadays the bullets have more energy so it doesn't protect anymore
@mastere61152 жыл бұрын
@cosmify Check the video at 20:25 hahahaha
@efraintarin392011 ай бұрын
dude you are insane, an insane genius, instead of modifying an organism, making a new spider, we get spider beer, spider beer concrete, spider beer kevlar, spider beer plastics. man, respect
@saturnsgodv14 жыл бұрын
Ahh yes of course.... I have no idea what he's talking about 90% of the time
@joaopedrogomes26254 жыл бұрын
I just started a bachelor in biotechnology and the frustration I feel when watching his videos is immeasurable
@joaopedrogomes26254 жыл бұрын
@fuck google same deal, most of what he says I don't understand properly but I still love the content and it kinda makes me study harder :)
@McPhysX4 жыл бұрын
@@joaopedrogomes2625 come back in 3 years, now i am doing a masters in bioengineering and looking at those types of videos and actually understanding everything and know how he achieved it is a whole new world :)
@aduzzz33224 жыл бұрын
@@McPhysX and recommendations on where to start to be able to understand this stuff better? I'm only minoring in bio but I love these videos though I can barely understand what he's saying.
@McPhysX4 жыл бұрын
@@aduzzz3322 On youtube I don't know, though there are plenty of indians detailing individual concepts. I'd recommend taking any course on Biochem, Biochemical analysis and genetic engineering, or even bioinformatics. It's not complicated once you've seen the majority of the basic known Bio analysis techniques ( sequencings, blots, proteomics, hybrids etc)
@natureabioros86864 жыл бұрын
This is so cool, as a researcher who works with genetically engineering microorganisms to produce proteins, this is a huge inspiration
@LaceworkDreams4 жыл бұрын
Man really said "fine. I'll do it myself."
@aloysiuskurnia7643 Жыл бұрын
Vortexing nad pipetting up and down is one _hell_ of a difference of force.
@sarahellis74294 жыл бұрын
I think you did a really good job on the visual side of this video, the diagrams, infographics, tables etc. As a graphic designer I was impressed. Awesome video.
@download3334 жыл бұрын
I'd recommend learning the basics of python or another simple scripting language. Your method of random generation of genes is very cool, but a script could be doing all that copying/pasting for you and churn out genes as fast as you can ask for them. You can also have the script do Longest Common Sub-sequence analysis to ensure there's no large repeating blocks that could mess up printing (I assume the synthesis companies do something like this on their end when deciding which orders to reject). Also, your videos have taught me more about practical genetic engineering than years of school ever did. Good shit 👍
@OLDFRYEGUY4 жыл бұрын
also, why? whats wrong with the sequencer? are you telling me its inappropriately named?
@codeout65124 жыл бұрын
I've thought about that too lol. I usually write a quick script for stuff like that.
@calebgebhard78634 жыл бұрын
Peter Parker: Would Like to Know Your Location
@ashketchum65854 жыл бұрын
Underrated comment😂
@syntaxusdogmata33334 жыл бұрын
@@ashketchum6585 Indeed. It could have 10x the likes, and still be underrated.
@lancewalker25952 жыл бұрын
This is by far the most incredible, most inspiring thing I've ever seen. People like you are the future, I truly believe that. Unbelievable.