Imine and Enamine Formation Reactions With Reductive Amination

This organic chemistry video tutorial provides a basic introduction into imines and enamines. An imine can form in the reaction of a ketone with a primary amine and enamine can be produced by mixing a ketone with a secondary amine. The imine and enamine can be reduced to amines by reductive amination with NaBH3CN.
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[@vishkavayomi4726]

Thank you!! I watched your most of organic vdos.. It helped me lot!! Your explanation is very clear and understanding... thank you again ☺️

[@oliviacasale8941]

My textbook does imine formation differently here a NA is done first by R-NH2 to form an oxygen anion and then that is protonated with H-A+

[@lavina3535]

The enamine formation mechanism wasn't there in my textbook. Thanks for explaining :)

[@TheMaskedRacoon1]

I think imines and enamines can also be reduced to secondary and tertiary amines using Aluminum Galinstan amalgam in an ethanol distilled water solution.

[@weezy224]

just wanna listen to your voice before i sleep every single day

[@ajnewyork3690]

at mark 1:04, you mentioned that the more substituted alkene would form. But in the organic chemistry as a second language book, it said the less substituted alkene would actually be the major product. Which one is correct?

[@tomatrix7525]

AJ New York well, not sure why that book says that, but more subbed alkene always form as a major product as they are more stable.

[@tomatrix7525]

Unless the stereo chemistry prohibits them forming

[@diegogaetes.9628]

Hofman´s rule... Depends on the context

[@siddharthagotur7449]

I think you are talking about the hoffman product. It happens with E2 elimination reactions generally in which the nucleophile is bulky (e.g: t-butO⁻) or if there's a bad leaving group present (NR3 ⁺).

[@ranjithvurs1086]

I know saytzeff product is major still I saw in some video that, in this enamine formation, double bond formed is Hoffman cause of repulsion of methyl group or something

[@nvel5612]

missed a plus charge on N after NH3 attacked carbonyl. ~3:40

[@mdjabir9817]

Really good explaination

[@jesusmrosario-claudio4104]

Thank you once again.

[@misakichan372]

U R The best👍🏻👍🏻

[@SnehaR380]

how many here coz enamine came in Jee unexpectedly??

[@Nobody-xp6ip]

me

[@bredbutter]

Me

[@anushkadixit49]

Mee , i was doing jee mains papers of 2022 and it came unexpectedly 😅

[@SnehaR380]

Got 5611 rank in 2023 Feeling nostalgic Now in iiitA and conditions don't seem any better I m studying more than Jee here and seeing 200 students unplaced in final year in such a repute clg is really heartbreaking ND demotivating

[@factshut8663]

​@@anushkadixit49same 😅

[@lalmalsawmachhangte620]

Great job...thanks

[@edoardocavacece3713]

Shouldn’t the ammine get protonated instead of the carbonyl? Then the protonated ammine it’s not suitable anymore as a nucleophile..

[@yungcashregister8587]

Thank you so much!

[@davidd5682]

Thank you!

[@sanskarkurude]

Thank you ❤️

[@patrycjaprzedwojska1072]

I've seen different mechanism for reductive amination, how do I know if this one is the right one?

[@goofyaaahhandle]

mechanism arent real for the most part, so like a single reaction can have multiple correct mechanisms considering none of them is scientifically impossible... this is what my prof said atleast

[@dogeyna9181]

You should try solving IIT &JEE papers 😜

[@taniapradhan7480]

👌👌👌

[@zahraafadhil5569]

👏👏👏

[@razasyed575]

mashallah

[@goatmilkofficial]

Sir, you are the shit

[@anshukashyap2063]

am i the only one from class 11th studying it.