Immune Thrombocytopenia (ITP) - Most COMPREHENSIVE Explanation - Hematology

Immune Thrombocytopenic Purpura (ITP) (aka Idiopathic Thrombocytopenic Purpura or immune thrombocytopenia)…autoimmune attack on platelet receptors leading to bleeding (petechiae, purpura,and ecchymosis)…Order bleeding time, platelet count, PT, and PTT. Most COMPREHENSIVE Explanation.
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Bernard-Soulier Syndrome (BSS) is an autosomal recessive (AR) disorder characterized by a defective GP1b platelet receptor leading to a problematic platelet adhesion process (primary hemostasis).
Glanzmann Thrombasthenia (GT) is an autosomal recessive defect in the GPIIb/IIIa (GP2b/3a) receptor on the platelet which leads to defective platelet aggregation.
Ristocetin Cofactor Assay (RIPA) is usually abnormal in cases of Bernard-Soulier Syndrome (BSS).
Bleeding time is prolonged, platelets are big in size, but few in number (Macrothrombocytopenia).
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Platelet count is one of the lab tests used by a doctor or a hematologist to assess whether your platelet number is normal, low (thrombocytopenia) or high (thrombocytosis).
Bleeding 🩸 time (BT) is another test for platelet function.
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[@adin200]

you know, I have to have this.....

[@withlessAsbestos]

Hey, I used to hear that low platelets could cause irritable skin and more pain; however I have been actively told by one out of 4 hematologists that I’m making that up entirely. Is it a real thing?

[@rehabhh5834]

Really..افضل وأروع شرح لهذا الموضوع ..افتخر انك دكتور مصرى فاهم فى الطب لهذه الدرجه

[@MedicosisPerfectionalis]

Thank you 😊

[@fatimaayman21]

مصري؟

[@aniokeozonnia6961]

I just discovered your videos and I've been blown away. You're truly gifted.

[@MedicosisPerfectionalis]

Thank you so much 😊

[@kaylakeiser-dl3jw]

Pinched nerves could cause homeostasis... So far two homeostasis was mentioned, primary and secondary.

[@kaylakeiser-dl3jw]

Some of these cells could caused problem by having too much or too little disease...

[@kaylakeiser-dl3jw]

By 4 times 20, less bacteria

[@acecombat3430]

Thank you for the excellent video. You should make a PDF book that collects and summarise all your lecture series. I would happily buy it. Keep up the excellent work.

[@addisonfearing8694]

Having ITP really sucks. I’m 14 and was diagnosed at age 7, so I’ve had it about half my life. This was an amazing description, I couldn’t have done it better! I showed it to my friend when she just wouldn’t understand and it got to her. Thanks!

[@MedicosisPerfectionalis]

Thank you 🙏

[@Ieatpastaday]

I understand when I was younger I got diagnosed but I'm still doing ok we got this

[@withlessAsbestos]

I just realized I’ve had it for 75% of my life now.

[@wildrose912]

I’m a 64 y.o. F chronic ITP x 5 yrs and this was such a fun lecture! Yesterday my plates were 50. I’ve got bruises, bleeding scratches from scratching an itch and my tongue is swollen and purple and has 3 or 4 big painful sores each side. The inside of my lips are purple and it looks like I’ve been drinking purple kool aid. Anyway, I dyed a purple streak in my gray hair for fun today.

[@PremiumUserUltra]

Sorry to hear you're suffering with it

[@avash__6158]

Watching your videos make me emotional. Im often lost and frustrated in medicine. But you have god status in teaching. No way any professor can make me understand so easy. You are the best.

[@MedicosisPerfectionalis]

Thank you so much, dear :) You made my day!

[@aremedyproject9569]

Love this guy. He gives me some confidence in, and compassion for, my doctors!

[@nelchuchunel5967]

Im doing JR in Haematology with my minimal medical knowledge. Nobody has time to teach me, not even my consultant. Im learning alot from your videos

[@MedicosisPerfectionalis]

Thank you 🙏 I am honored!

[@centerpromise5900]

Excellent!!! Should I be ashamed of learning Heme on KZbin? Not when it’s explained this well and made so relevant for us oral learners!!!!

[@MedicosisPerfectionalis]

Thank you so much 😊 I am glad 😃 that you liked my videos! Most of my learning cane from people that I never met! So, you’re fine 😎

[@roxyo2783]

i have a hematology exam tomorrow thank you soo much you are my savior!!

[@MedicosisPerfectionalis]

You're very welcome 😊 Good luck 🍀

[@furbelox5821]

Love you man. I really appreciate how you put effort in understanding and not just memorizing.

[@MedicosisPerfectionalis]

Thank you 😊

[@rahmahl5762]

Who else is gonna explain this to you like this HAHAHAHAHA😂♥️

[@MedicosisPerfectionalis]

Thank you so much 😊

[@Benrime]

Like the "medicine make sense once you understand what the flip you're talking about." Busted out laughing. Making me more motivated to learn this for my class. :P

[@MedicosisPerfectionalis]

Thank you so much 😊 I appreciate it!

[@heinthuyahtet5081]

Why are most of Professors not good at teaching?LOL

[@ibbydutoit9528]

@@MedicosisPerfectionalis what type of medication is polygam?

[@ektanain7400]

“Idiopathic which means we are idiots and we cannot figure out the pathology.“ “Intellectuals and their verbal virtuosity.” “I think I should stop talking.” LOVE IT! 🤣

[@user-dl8ox4lt3k]

When you explain the mechanism of IVIG, anti D antibody, I got chills bro…. You are amazing

[@MedicosisPerfectionalis]

Thank you 😊

[@ThexEpicxKi]

I was born with this but only understood it at a basic level like bruising easily having to see the hematology and needing platelets when I got surgery as a kid so now that I'm 26 this is very informative thanks

[@MedicosisPerfectionalis]

Thank you 🙏

[@freddybabu5698]

U dont have spleen now?

[@hasanhuseyinsucu]

Geçmiş olsun. Dalaginiz alındı mı? Tedavi sistemi nasıl işliyor sizde?

[@anaradu8118]

"Who else is gonna explain to you like this, your professor? Give me a break" EXACTLY!!!!! i came here precisely because they don't freaking explain!!!! You're awesome, thank you so much ❤

[@youssefwael-p9y]

I just discovered your videos and I've been blown away. You're truly gifted.

[@MedicosisPerfectionalis]

Wow, thank you! I appreciate you so much! Please help me by sharing my videos with others!

[@haneenbaraka4852]

I am super proud that you're Egyptian I am out of speech seriously One of my favourites that You're using your voice tone incredibly well that makes me feel like i am listening to rhythm of music and stuck to my head

[@MedicosisPerfectionalis]

Thank you!

[@alyssab9813]

Had ITP for the first at 4 years old. Didn’t have issues again till I was 19 and had to stay in the hospital with plate levels at a 2! Go in for blood testing about once a month now :)

[@dec35]

spent a week in the hospital in January cuz my platelets levels were

[@PremiumUserUltra]

@alyssab9813 Good luck 🫶🏻

[@khaaldaraagooo978]

Wow am I the only resident who is impressed !! .excellent work thanks .

[@MedicosisPerfectionalis]

Thank you 😊

[@vanderhell_ke]

Had ITP since I was 8. It's in remission now. Don't have to worry about until my 50s. Good to know that people go through the same thing I did.

[@johnvincentconde3412]

What do you mean by remission?

[@mochiibonbon6700]

@@johnvincentconde3412 it means that its all good for now

[@chideranwosu5396]

The relief I get seeing that medicosis has a video on a topic I find difficult ❤🥺. Keep saving dreams sir❤🥺

[@MedicosisPerfectionalis]

Thank you! I am honored!

[@spikewap]

I watched many different medical video producers on youtube , you are different level! Bravo! I hope you get more subs and you get what you deserve!

[@MedicosisPerfectionalis]

Thank you so much 😊

[@aditi3586]

My sister has this problem and is having multiple bruises on her body. Please pray for her 🙏

[@vickykadam-v7p]

is she recovered from it?

[@medisum9]

Whyyyy youuu aree sooooooo gooooooodddd🥹🥹💗 indeed the best ever explanation on the surface of earth.... Why I dont get this channel in my early medical school.... After 5 years finally i got to understand ITP TTP and that stuff crystally clear....❤

[@MedicosisPerfectionalis]

Thank you so much! Please help me by sharing my videos with others!

[@medisum9]

@@MedicosisPerfectionalis let me rock among colleagues for a day or two and make them curious about resource then I will share with them😂🥳

[@aurangzebkhan9497]

I'm going to share ur lectures in different medical clg groups of Pakistan coz u deserve it inshallah I are gonna reach 1 M soon

[@MedicosisPerfectionalis]

Thank you so much 😊

[@shyampatel999]

I have never learned anything so much effective in funny way. You are genius.!🙌

[@MedicosisPerfectionalis]

Thank you so much!

[@millennial_lovetk]

why i am laughing and studying at the same time .. it never happened before !! loved it

[@MedicosisPerfectionalis]

Thank you 🙏

[@purple_army4091]

Oo Are you army💜???

[@millennial_lovetk]

@@purple_army4091 yes !! you too ?💜

[@purple_army4091]

@@millennial_lovetk yess 😄🙆‍♀💜

[@millennial_lovetk]

@@purple_army4091 omg borahae😂💜

[@HanLaoBan]

Thanks for the explanation. You are awesome. I also realized you talk faster than before. In the past, I use 2x sped, and now 1.5x!

[@victoriabilenko9289]

First time on your channel. WOW. So clear, good humored, great pace - enjoyable! Thank you!

[@MedicosisPerfectionalis]

My pleasure!

[@Mugshot214]

I have ITP. Was diagnosed 13 years ago. This was well done and I plan to just send this video to people when they ask me to explain it. 😂

[@MedicosisPerfectionalis]

Thank you 🙏 Good luck to you!

[@Mugshot214]

@@MedicosisPerfectionalis Thank you :)

[@MedicosisPerfectionalis]

My pleasure 😇

[@kazehayaluca7966]

I wals also diagnosed with ITP last august and it was great but now I tried to have bloodtest again and my platelet drop to 50 😭

[@mochamadchairulridjal1514]

lmao I'm here for the same reason

[@medicaaam2197]

Acute crisis * IV Sterios *IVIG *plasmaphoresis *Anti D antibodies For maintenance * Steriods * Splenectomy * Elthromopag ' rotilotism(increase platelets) ' Rituximab and other immunosuppressive (decrease immune reaction)

[@morelostonatiuhperezmendoz9950]

Dang! It really was the best video about ITP. Also, besides the autoinmune diseases and HIV or HCV infections, i was thaught that the children frequently have a lower airway respiratory viral infecction previous to developing mild ITP.

[@MedicosisPerfectionalis]

Thank you so much 😊 You're right, viral illness comes before ITP in children.

[@AppendixVermiformis]

Like post-infectous Henoch-Schonlein purpura?

[@roshenakthar7065]

Literally the best explanation for ITP on the earth 😅

[@MedicosisPerfectionalis]

Thank you 🙏

[@Farheen78601]

There is no doubt i would ever found better explanation fot it🎉

[@boubountobouboune5529]

Like you said, tis was the best ITP explanation in the planet!!

[@MedicosisPerfectionalis]

Thank you 🙏

[@Dr.aya16]

OMG this is actually the best explanation i've ever heard and seen ! THANK YOU bro

[@MedicosisPerfectionalis]

My pleasure!

[@ibrahimzuraik727]

that was an amazing video you deserve our support doc

[@MedicosisPerfectionalis]

Thank you 🙏

[@N1Rguitar]

Awesome! And just a couple of weeks before my hematology exam.

[@MedicosisPerfectionalis]

Thank you :)

[@phantom-quran-relaxation.1069]

indeed it is the BEST explanation of ITP. thank you so much.

[@MedicosisPerfectionalis]

Thank you 🙏

[@mogaleboshoga1185]

Jesus this literally was THEE best crash course on ITP

[@MedicosisPerfectionalis]

Thank you 🙏

[@kokxiaojun7962]

First time laughing so hard while watching medical video XD You turned the boring lecture into interesting one! Thank you !

[@MedicosisPerfectionalis]

My pleasure 😇

[@nahidrahman4341]

I wish I found you during my med school.Thanks a bunch..

[@MedicosisPerfectionalis]

My pleasure 😇

[@bitterguard5233]

This was the best ITP explanation on the face of the earth ✌

[@MedicosisPerfectionalis]

Thank you so much ☺️

[@ximenaarias2879]

Amazing! Love your videos. Impressive mastery of the subject.

[@MedicosisPerfectionalis]

Thank you 😊

[@rahmahl5762]

ITP has a sensitive meaning in my life as I saw a long story of it with my best friend ever and she's still suffering from it" Thanks for your video

[@MedicosisPerfectionalis]

I am sorry to hear that

[@withlessAsbestos]

Rahma Mahmouudd And in my life it means I can’t play sports.

[@mochiibonbon6700]

@@withlessAsbestos i also have itp but somehow my doctor let me keep on doing ballet

[@withlessAsbestos]

@@mochiibonbon6700 your dr. Doesn’t play by nobody else’s rules.

[@gulmakayzaman1969]

this is not only informative but also entertaining ! love you who ever god's awesome creation you are xD

[@MedicosisPerfectionalis]

Wow 🤩 Thank you so much 😊

[@savvymedicine9350]

It really was the best ITP video !

[@somambbbaz6601]

No one else can explain it like this And my professor needs your lectures Too I guess 🤣🤣 Thank you 🙏 You are awesome 😍

[@MedicosisPerfectionalis]

Thank you 😊

[@shivanichhabra1166]

nice video meri sister ko ye problem almost 2 saal se h...bhut treatment karane ke bad bhi koi fayda nhi hua fir hamy kisi nay planet ayurveda k wary m bateya or bo planet ayurveda k g-plat capsules use krny lgi ab onki problem bilkul thek hai thanks to planet ayurveda

[@mitali3j]

Kya aapki behen planet ayurveda doctor se mili ya online hee consult kiya?

[@lroman.3939]

OMG thank you so much, i love how you explained ITP ♥

[@MedicosisPerfectionalis]

Thank you 😊

[@rubymusqan3792]

as always, wonderful videos. i really like how u repeat information from ur previous videos in the playlist until it becomes permanently embedded into the seeds of my brain. is there a video coming up on DIC?

[@MedicosisPerfectionalis]

Yes, it’s coming up! Thank you so much 😊

[@rubymusqan3792]

@@MedicosisPerfectionalis you are the best♥️

[@MedicosisPerfectionalis]

Thank you 🙏

[@isitedible7121]

Sounds fun. It especially sounds fun when you get it at 9. Good times.

[@aadyajha6751]

Literally no oneeeee ,can ever explain like this 🙌🙌🥰

[@MedicosisPerfectionalis]

Thank you so much!

[@GabbyLouis]

oh my...why i just know your channel Sir. The best explanation ever. PERFECT Prof

[@MedicosisPerfectionalis]

Thank you so much 😊

[@lisazhaoqingqinglisa6888]

@@MedicosisPerfectionalis 😁😁

[@MedicosisPerfectionalis]

😊😊

[@lisazhaoqingqinglisa6888]

@@MedicosisPerfectionalis

[@zayneb98]

U are my hero in medicine Thank u 🥺❤️

[@zainabalkurdi6175]

It’s really the best on the face of the planet , Really thank u 🙏🏻

[@MedicosisPerfectionalis]

My pleasure 😇

[@ajmalnazir2120]

Excellent presentation please speak slowly so that we can understand in better way again I appreciate your presentation thanks

[@daniaizzah4335]

omG i really love it when you're implementing soft medical puns during the teaching.. the laughing wakes me up haha truly a passionate professor you are

[@MedicosisPerfectionalis]

Thank you so much, Dania! I appreciate you!

[@SajitaKu]

Your videos are blessings in this lockdown!🤗🤗🤗

[@han-br5by]

You saved my future thank you very very much 🥺

[@MedicosisPerfectionalis]

My pleasure 😇

[@salmaali790]

شكرا ليك يا دكتورنا العظيم ❤❤❤❤

[@ranulpeiris1083]

you are good ! It's very understanding. really appreciate your effort ! but some stuff you say are distracting in the middle of teaching.

[@pujasaha4956]

The way you explain is great 👌👌👍👍

[@salmaali790]

Actually no one can explain like this 😅😅❤❤❤❤❤

[@MedicosisPerfectionalis]

Thank you!

[@dawnhoran3353]

Brilliant! Love your teaching methods!

[@MedicosisPerfectionalis]

Thank you 🙏

[@marear1979]

I have lived with Chronic iTP for almost 20 years. This is by far the best explanation I have seen out in the world. Does iTP cause other complications such as to the liver, heart, kidneys?

[@withlessAsbestos]

Ehlers Danlos Does, which is supposedly a correlated disorder.

[@poornimachowdary1911]

Love the way u explain so detailed and so simple!!loving to study after cing ur video

[@MedicosisPerfectionalis]

Thank you 🙏

[@victoriaokorafor8765]

Medicosis is so fun and savage at the same time😂😂 Love you

[@MedicosisPerfectionalis]

Thank you!

[@jeremiahbaker6396]

I could never thank you enough

[@MedicosisPerfectionalis]

You’re always welcome 🙏

[@jaimekaimero2912]

Stay away from azithromycin and clindamycin. Especially Azithromycin. Platelets were holding steady between 100 and 120,000. After 7 days of azithromycin platelets went to 50 After 1 month recovered but to just 80,000

[@omaralmorsy1322]

U're the best man ❤

[@MedicosisPerfectionalis]

Thank you!

[@alinakhachaturian9706]

Huuuuuuge thank you from Russia, your videos are very very helpful 🙌🏻

[@MedicosisPerfectionalis]

Thank you so much 😊, Alina! And thanks for supporting me on Patreon. It means the world to me!

[@rathodnehal2869]

you are a hero of students man 💪💪😍😍

[@fabiolaguzman209]

I just found your channel. You’re awesome!!! Thank you so much for making videos 😃

[@MedicosisPerfectionalis]

My pleasure 😇

[@babitaojha4845]

wow what an explanation, loved it ❤❤

[@MedicosisPerfectionalis]

Thank you so much 😊

[@ExoticxSenpai]

Came across this video today I was diagnosed with itp today wanted to get more in depth my platelets were supposed to be at 150-400 per whatever and mine are at 5

[@hasanhuseyinsucu]

Geçmiş olsun. Ben de İTP hastasıyım zor bir hastalık. Hiçbir şeyi kafaya takmayın.

[@whatapainx5420]

you're humour really made learning fun thank you ❤❤

[@MedicosisPerfectionalis]

My pleasure!

[@mohsinlover9140]

May Allah keep you happy. ❤😊

[@MedicosisPerfectionalis]

Thank you 🙏 You too!

[@totallythandi2555]

This is crazy high yield. THANKS

[@MedicosisPerfectionalis]

My pleasure 😇 Thank you so much for watching!

[@ABC-fv7ow]

Excellent explanation.Keep it up medicosis

[@askask7468]

This video is amazing. Good job.

[@MedicosisPerfectionalis]

Thank you very much!

[@priyalverma2442]

Such a interesting explanation,thank you ❤

[@MedicosisPerfectionalis]

My pleasure!

[@snowdiamond5740]

I missed your great work Genius ..many thanks ♡

[@MedicosisPerfectionalis]

Thank you so much 😊

[@halooja4708]

Thank you sooo much your explanation is fantastic😍

[@MedicosisPerfectionalis]

My pleasure!

[@javierrodrigochavezaguirre2499]

Literalmente es el mejor maestro de hemato JAJAJA, muy bueno tu video

[@harinisuresh321]

I cant stop loving ur videos sir you are just amazing

[@MedicosisPerfectionalis]

Thank you so much 😊

[@hectorbas.4558]

Excellent video. I just didn’t understand why are the platelets big?

[@MedicosisPerfectionalis]

Thank you so much for watching! I don’t have an answer to your question, unfortunately!

[@sahaabnoor8831]

BEST VIDEO EVER. LOVE IT SOOO MUUUCH

[@MedicosisPerfectionalis]

My pleasure!

[@Be1smaht]

Ok students review this close to the middle or end of your studies. That’s where it fits in

[@shahabuddin6149]

Super super informative lecture thanks sir a lote

[@PatriciaSantos-qy9dl]

omg ive been waiting for this

[@MedicosisPerfectionalis]

Thank you so much :)

[@smp1446]

Thank you for the GOOOOOOOOOOOOD video!!!

[@MedicosisPerfectionalis]

My pleasure!

[@prakashn960]

Enjoyed ❤️. Enlightening

[@MedicosisPerfectionalis]

Thank you!

[@luffy101n2]

Professor kindly tell me what are your reference books for hematology?? Pls plsss

[@angelanambiro4788]

Thank you for this video.

[@MedicosisPerfectionalis]

My pleasure!

[@DaniloGebrin]

Man, you are very good and even funny in a nerdy way lol

[@MedicosisPerfectionalis]

Haha 🤣 Thank you so much ☺️

[@sabinearezki2823]

Medocosis I love you you are a life saver thanks a billiin times

[@MedicosisPerfectionalis]

My pleasure 😇

[@mariem9296]

U are my hero thank u so much 💜💜

[@MedicosisPerfectionalis]

Thank you 🙏