Immunology: BCR/ antibody genetic diversity mechanisms

[@hudababat181]

Thank you for this video Can you add the ppt on the description box

[@artinmohammadi4802]

thank you so much, you made a lot of complicated stuff easier to learn

[@medaphysicsrepository2639]

Thanks alot for the feedback, be sure to let me know if you have qustions

[@purplepanda9794]

Same textbook as my course, great vid!

[@medaphysicsrepository2639]

Thanks for leaving a comment, immunobiology by Janeway?

[@sunusaca6876]

May I know which book it is?

[@medaphysicsrepository2639]

there are two: immune system by peter parham and immunobiolgoy by charles janeway, both are great!

[@purplepanda9794]

I’m using the one by Peter Parham! :)

[@jongelb9603]

@11:00 signal joints actually don’t immediately get degraded-these Recombination Excision Circles TREC’s & BREC’s remain inside T and B lymphocytes and are routinely assayed in newborns via heel stick - r/o immunodeficiency

[@medaphysicsrepository2639]

I did not know that! thanks for sharing

[@schwaswe1]

Really the best vid i could find on somatic hypermutation. But still not as detailed as our teacher is expecting us to understand hypermutation (unfortunateli his script is incomprehensible) Anyway, thanks a lot for your awesome video, now i got the big picture

[@medaphysicsrepository2639]

+Swen S I try not to focus too much in depth on molecular biology/cell biology type mechanisms in this class, It would be nice to learn them in the context of immunology, but my god would that be hard for a student to have to learn all at once (we never mention developmental biology and / or epigenetics in this class at all unfortunately) I am curious as to what all you have had to learn when it comes to understanding this stuff and what for though?

[@aliyaf706]

Best/most comprehensive video I've watched on this topic!!!

[@medaphysicsrepository2639]

+Aliya F Thank you so much Aliya, Im glad you found it helpful , may I ask what brought you to it ?/what do you study ?

[@aliyaf706]

+thomas underhill I'm doing an MSc in immunology :)

[@medaphysicsrepository2639]

+Aliya F NICE, so I assume you study in europe? is a thesis optional or not ? I study in america so our education system is quite different.

[@aliyaf706]

Yeah I study in London. In my course the thesis was obligatory. Some courses at other institutes don't have a thesis, only taught modules, exams and coursework. Do you study Immunology as well then?

[@medaphysicsrepository2639]

Do you know what you plan to do a thesis on ? immunology isn't like most fields, theres a lot of confusion still getting worked out in the details, one of the things that attracted me to it. and no i don't technically study immunology in the same context as you probably do. In the USA after you get a bachelors, you have to decide what program you want to go into for PhD or Masters (which i assume is the same as the UK?) problem is I haven't really decided on any specific path so I just sample into things here and there lol

[@cathyzhao3200]

BEST VIDEO EVER! THANK YOU SO MUCH!!!:)

[@medaphysicsrepository2639]

you are too kind, feel free to watch some of my other videos, feedback is most appreciated ^w^b

[@whitneyharvey850]

Thank you so much for linking me to this video. It's exactly what I was looking for!

[@medaphysicsrepository2639]

+Whitney Harvey You are most welcome, just curious, how did you find my channel/videos?

[@whitneyharvey850]

+thomas underhill I'm in the midst of writing an essay on TCR diversity, and I like to watch KZbin videos for background before I dig into the scientific journals. Anyways, I just searched vdj recombination and your video came up ☺

[@medaphysicsrepository2639]

+Whitney Harvey Thats odd considering that I don't monetize, what do you study ? medical/professional school ? bachelors ?

[@whitneyharvey850]

+thomas underhill I'm doing my senior research for a premed bachelors

[@medaphysicsrepository2639]

thats awesome! You seem very capable, I have no doubt you will get into medical school!

[@kunukandayashodha2166]

comprehensive diagrams

[@medaphysicsrepository2639]

thanks for the comment