Drugs for Cardiovascular Health with Dr. Ben Bikman

In this week's episode of the Metabolic Classroom, Dr. Ben Bikman welcomes viewers to a discussion on commonly used cardiometabolic and weight loss drugs. The focus of this particular lecture is on drugs targeting heart disease, a leading cause of mortality globally. Dr. Bikman acknowledges the controversy surrounding cardiovascular drugs due to the severity of heart disease and the passionate advocacy for drug therapies.
The lecture begins with an overview of two main categories of cardiovascular drugs: those addressing blood pressure and those targeting cholesterol levels. Dr. Bikman explains the significance of blood pressure in cardiovascular health, emphasizing its correlation with heart attacks and hypertension. He delves into the physiological effects of high blood pressure, likening it to over-inflating a balloon and causing stress and damage to the inner lining of blood vessels.
Moving on to drugs that control blood pressure, Dr. Bikman highlights the potential impact on insulin resistance and mitochondrial function, crucial factors in heart disease risk. He discusses common classes of antihypertensive drugs such as beta blockers, ACE inhibitors, calcium channel blockers, and diuretics, detailing their mechanisms and side effects.
Transitioning to cholesterol-lowering drugs, Dr. Bikman discusses the controversy surrounding the assumption that cholesterol is solely responsible for heart disease. He challenges the oversimplified view of LDL cholesterol's role in plaque formation and suggests alternative paradigms, including the immune response to infections in blood vessels.
Dr. Bikman then discusses two classes of anti-cholesterol medications: PCSK9 inhibitors and statins. He explains how PCSK9 inhibitors increase LDL receptor expression to enhance LDL clearance and discusses potential side effects such as worsened insulin resistance and mitochondrial dysfunction. Finally, he explores the mechanism of statins in reducing cholesterol production and addresses controversies surrounding their use, including potential risks of developing type 2 diabetes and Alzheimer's disease.
01:31 Categories of Cardiovascular Drugs
04:58 Cholesterol Control Drugs
06:12 Challenges in Conducting Long-term Studies
07:29 Blood Pressure Medications
13:24 The Role of ACE Inhibitors
19:44 Diuretics: Forcing Kidneys to Dump Salt and Water
21:52 Unveiling the Role of Insulin
24:19 Dissecting Cholesterol Myths
26:49 The Fat Factor
38:23 The Statin Conundrum
42:12 Navigating Medication and Metabolism
#insulinresistance #metabolicsyndrome #metabolichealth #type2diabetes #type1diabetes #weightloss #intermittentfasting #intermittantfasting #fasting #lowcarb
Learn more at: www.insuliniq.com

[@christinaperez254]

Geeking out with Dr. Bikman is my new favorite hobby.

[@ilunabella]

Me too 😂😂

[@T-aka-T]

I think he might be the kindest man on the planet. As well as one of the cleverest. (A rare combo 😏)

[@ilunabella]

@@T-aka-T so true.

[@brucemckay6615]

👍👍👍👍

[@kc4596]

It would have been great if all my professors were just like you. The clarity in which you speak is so refreshing. Thank You!

[@Crimepaysaskapolitician]

I wish I could share this video with my doctor. She is a very strong advocate of statins. And never misses a opportunity to mention heart attack and stoke.

[@STEVEN_GUILBEAULT_BUFFOON]

yes had to fire my doc trying to push statins...,,was quite annoyed when I told him where he could stick his statins

[@Crimepaysaskapolitician]

@@STEVEN_GUILBEAULT_BUFFOON I hear you.

[@T-aka-T]

​@@STEVEN_GUILBEAULT_BUFFOON You suggested proctology as a solution to his problem? 🤔

[@ak-rx1ui]

Ever heard of Sutton's law?

[@T-aka-T]

@@ak-rx1ui classic flow-chart in lieu of diagnosis, eh? Akin to Ockhams Razor. Simplest will be right. Except that often, it ain't. Sutton is for med school beginners. Problem arises when they stick with the flowchart and never ever become actual intuitive diagnosticians. (Or am I wrong?)

[@cherylking1459]

60 yo who has a new lease on life. Thank you for your work and your approach. Understanding, knowledgeable, empathic,... Go Dr Ben!!!!

[@insuliniq]

Thanks for your kind comment.

[@kylegriffith2528]

You changed my life doc. You're definitely my favorite scientist. Currently pumping iron and getting ripped during your lecture!

[@jandenooij]

I have to say it again: dearest prof. Bikman: you really are a very very talented teacher! I 've had many teachers during my studies and professional lifetime but none of them had the gift to explain complex matters the way you are able to. Many thanks once again for all this information and please keep on doing this. Greetings from The Netherlands on a (again) rainy morning

[@insuliniq]

Thanks for your kind comment. Stay dry!

[@annettefowler4704]

I agree

[@bob16cl]

Thanks Ben for the free education. Love what you do brother. I really like the way you communicate. You make this very digestible and I appreciate that.

[@margomoore4527]

Digestible; cute.

[@insuliniq]

Thanks, Bob, for your kind comment.

[@yvonnekiwior9633]

Excited to watch this and listen to your BRILLIANCE!❤ Thank you for all you share that is so accessible to us🙏

[@khall999]

Dr.Bikman- thank you so very much🙏🏻 You are a gift to human kind. How precious your knowledge is on earth at this time… such a gift! Thank you so much

[@insuliniq]

Thanks for your comment. You’re kind.

[@24bellers20]

This is stunning. Thankyou Ben. Since I started following you on here and X my health has been transformed.👏🏻👏🏻👏🏻👏🏻👏🏻

[@jasonanthonywilper]

Thanks Ben! I love this series of videos.

[@victorhauk5973]

So my takeaway is that blood pressure meds work indirectly on blood pressure by altering other biochemical processes, causing other problems

[@zarimohammadinia2120]

Thank you so much fir sharing.🙏☘️

[@judithyoast31]

Thank you for your time and effort to explain each issue. Every year my doctor wants to put me on a statin. I keep saying no thank you……this is why I listen to you. I wish I could have been a student. Keep up the good work!!!!!!!🥰

[@insuliniq]

Thanks for commenting, Judith!

[@mamabear9389]

Thanks Ben. You are an amazing teacher!

[@1mnowek]

excellent , love the structure and simplicity! compact information easy explained, thank you

[@steponroach]

I absolutely love your respect and admiration for the female form and all its struggles and tribulations that a male body cannot remotely comprehend. Thank you. I also deeply appreciate that the sincerity of what you say is heard loud and clear, in fact it is felt. Reminds me of DAX country song about men. And, what a man struggles with. You two are yin and yang.

[@jimjackofall1510]

You are very knowledgeable and informative. Thank you

[@Ed-qn7vx]

Thank you so much amazing presentation

[@jolantamsk3894]

I really appreciate your lectures, and findings, dr. Ben. I’ve been listening for about a year and am not so worried about my ‘total’ cholesterol at all😇. Thank you. Many Blessings to you and yours.

[@insuliniq]

You too. Thank you for your kind comment.

[@prathapchandra1]

As usual excellent info. Real science

[@lindawilson8318]

Dr Birman is a gift to people interested in health

[@gracelynmeade5640]

Brilliant pod St so informative. Our doctors are glueless all they do is push big pharma drugs no talk on nutrition or lifestyle. Keep the podcast series going. Thank you for educating the common man

[@insuliniq]

Thank you for commenting.

[@davidgifford8112]

A first class, considered review of the primary drug tools for CVD management. Lipid (hot lesions) stenosis have left me a little perplexed. Assuming that the Glycocalyx is intact, I find it challenging for LDL to enter the arterial wall. However if there is damage (from sheer stress?) then that inflamed area should stimulate angiogenesis in the vas vasorum in which immature vessels can leak lipids and RBCs into the arterial wall. It’s just on x-Ray the lesions often seem to at bifurcation or acute direction changes likely to be subject to turbulence and stress. I see no reason why these venerable areas should be a favoured area for bacterial colonialism.

[@annettefowler4704]

Thank you! God Bless you and your family.😁

[@insuliniq]

You’re kind, Annette. Thank you. Same to you.

[@VicknairD]

Found this bullet point on Mercola’s website just this am while ordering a low carb breakfast before my weekly Bible study. Any comment? This is the kind of stuff that keeps people confused. We simply seek clarity, but instead find warring positions. “One of the foundational concepts of health that I’ve radically revised my thinking on is the idea that a low-carb diet is the best way to optimize your metabolic health. That was misguided, because when glucose is absent, your body releases cortisol to produce endogenous glucose. Cortisol sacrifices lean muscle mass, bone and your brain to make glucose, which triggers inflammation and impairs your immune function.” By the way, I thoroughly enjoyed reading Why We Get Sick. I’ve passed it on to my 95 year old, low carb eating, mother in independent living who wonders why everyone around her is so unhealthy.

[@HEARTANDSOULOFMINE]

Yes! I read this MERCOLA article, too! So confusing. And his breakfast of champions watermelon breakfast. I keep wondering how he can eat all that fructose each day because we know how damaging too much fructose can be to the liver and other organs. I respect MERCOLA but that article makes me wonder how much else he has proposed that we ourselves follow and now he believes it is detrimental? Is he still selling a supplement for that revised protocol? Not a comfortable thought😮.

[@T-aka-T]

I think he has dropped his bundle and gone feral. Got in a lather over You-Know-What and became just irrational over it (as seems to be the Extremo Way). It's a pity. He used to be sane. Now lives down a rabbit hole.

[@wocket42]

When glucose is too low, the body will release glucagon, not cortisol. Cortisol is a stress hormone (stress at work, running marathons, etc). It is real, but has nothing to do with low glucose levels. Also: when you eat low carb, you will most likely be ketogenic. Ketones spare muscle mass. The body/evolution is not stupid. Also bone and brain are not sacrified. What might sacrify brain and bones is a high fructose diet.

[@T-aka-T]

@@wocket42 Except that the Dawn effect seems to be a cortisol-driven "get up and get going" signal that results in a glucose hit.

[@ak-rx1ui]

First time that I hear of 'Mercola'. Based on his learned observation, next time I'll keep my 12foot barge pole ready😅

[@carlloeber]

What you have said about the unreliability of the studies that by surveys and so much variation in the lifestyle and other important factors of the subjects in these studies. I'm not a scientist, but this is something I've tried to tell my doctor when he tells me about these studies. There are so many different variables. Sleep stress, exercise diet drugs. You name it. How can you isolate one factor for instance whether they're taking statins or not?

[@gracelynmeade5640]

Thank you

[@brucekmules]

Dr. Bikman needs to have a video discussion with Dr. Brownstein regarding iodine.

[@annalexander6042]

Thanks for your help I understand you

[@AliceFarmer-bg4dw]

Professor Can you please explain in detail the Randle Cycle?

[@saliyafitness]

Nobody explains like you. 🙏🙏🙏

[@KenJackson_US]

I am *_delighted_* to be off of blood pressure medicine. I took Norvasc and then Atenolol for decades, but thanks to my keto diet my blood pressure is normal without any medication.

[@mcfeather1330]

Love your fire truck analogy

[@AliceFarmer-bg4dw]

Hello Professor. Can you cover the mitochondrial effects on these pharmaceutical options? We would like to know things like CoQ10 and other mitochondrial dysfunction from drugs. We would like to know if mitochondrial dysfunction is part of the root cause of these disease?

[@jamesgordon8867]

Ought to be a CEU because you look from a mitochondrial involvement. You & Ninja Nerd are truly the best 😊🎉

[@AliceFarmer-bg4dw]

Dr. can you cover the Randle Cycle? We can not get a good straight answer.

[@petercyr3508]

You need to think about what if all the plaque components in the coronary arteries dont come through the endothelium but through the vaso vasorum (the back side). And this in respose to an injury or inflammation.

[@shelleygower9843]

Please do a deep dive into LPa 🙂

[@deborahcollins6983]

Thanks!

[@insuliniq]

What a kind thing to do, Deborah. Thank you so much. My team told me that they saw you sign up for a free Basic Membership on my website. Thank you for doing that as well. Let us know if there is anything we can help you with.

[@annalexander6042]

Yes I take them

[@Frank-kq2ym]

Dr. Bikman I’m grateful to you and these videos. My life choices have improved and with time I have been healing and recovering metabolically. How can I get a meeting with you? I’d love to have some of your counsel and support. Thanks in advance. Frank

[@insuliniq]

Thanks for your question. You may want to go to our website and ask my team: www.insuliniq.com

[@annalexander6042]

Yes I take

[@veydajar]

Looking at Fig.2 in the centenarian study, it appears that only the lowest quintile (

[@annalexander6042]

Yes I take that

[@Rita-pb8sh]

Thanks

[@insuliniq]

You’re both generous, and kind. Thank you. I appreciate. Please let my team know if there is anything we can do to help you: www.insuliniq.com

[@user-jl1sd9vr8k]

Dr Gil Carvalho Nutrition Made Simple says that the reason high cholesterol correlates with longer life is that many disease states lower cholesterol, causing the paradox. The higher cholesterol does not confer benefit, i.e. cause the lower mortality rate. His video offers about 6 examples of these U shaped paradoxical curves for different conditions. Could you please discuss this?

[@mariamorris954]

Love what you do, I appreciate you. I wonder what your thoughts are about elevated Apob if statins are appropriate for someone with diabetes t2 and already on BP meds. Id love anyones opinion. Im agonizing over this. Im not over weight but work hard to keep my eeight down

[@insuliniq]

Hi Maria. Thanks for your question. You may want to go to our website and ask my team: www.insuliniq.com

[@myronp243]

Those beta blockers almost stopped caused my pulse rate too low while in an operation!.Point 2 is why am I on statins when I never had a problem with cholesterol...ever.I had a stint put in and seems like nobody's paying attention.Point 3,get a CAC test before you start taking calcium. Calcium flowing in you blood stream is dangerous!

[@gregorysmith9563]

My PCP gave me Dr. Bikman's name when I asked him about fasting. Yet he also has me on Atorvastatin even though my Cholesterol levels are low (both LDL & HDL.) His explanation was that prescribing cholesterol lowering drugs is standard for people with heart problems. (I have A-Fib.) It's frustrating that there is some much contradictory information out there. You want to do the right thing but never know what the right thing is. 😕

[@insuliniq]

I understand, Gregory. Many people benefit from becoming part of our Insulin IQ Community, which gives a person more opinions and more experiences to draw from. Perhaps you would find value there, through group coaching with like-minded people working on their metabolic health: www.insuliniq.com/insulin-iq-community-membership-signup Just a thought.

[@susanbrockmann3635]

Love Dr Bikman. What about cholesterol meds and familial hypercholesterolemia, the genetic variant that causes really high cholesterol? In this case do experts recommend lowering it?

[@lmyers9999]

It’s not the generic high cholesterol production that is the problem- its only if that person also has the genetic increased clotting factors- that’s very recent research www.ncbi.nlm.nih.gov/pmc/articles/PMC9409002/

[@lmyers9999]

So it’s never the cholesterol that is the problem……

[@annettefowler4704]

i have high colesterol it's in my family, i am diabetic type 2, my docter has put me on crestor 5mg because he says that i wont be able to reduce it by diet,

[@lmyers9999]

New research shows that Familial Hypercholesterolemia is not a problem... it's the occasional accompanying Clotting factor that is the problem. Those with clotting factor are who have the problem. www.ncbi.nlm.nih.gov/pmc/articles/PMC9409002/

[@lewisschaffer9707]

Dr Bikman, can you look into the hypertension hypothesis? It smells very fishy - just like the lipid hypothesis. I have HBP (now 180/105) even though I've been almost keto on meat diet for the last 5 years. My blood pressure has been high since I was 23 y/o. (Now 66M). Maybe HBP serves a purpose and it doesn't cause vascular damage? Can you look into this? This needs a fresh approach. I stopped taking meds (pines, prils, tans) 4 years ago.

[@milofonbil]

Dr. Bikman, what is your viewpoint regarding an NMR lipids panel vs ApoB? Isn't the real concern only small particle LDL that can make it into the endothelium?

[@wocket42]

Even that is not clear. Some say the LDL firefighter do not come from the damaged blood vessel itself, but from the "micro blood vessels" that nourish the affected blood vessel.

[@wsclesky]

Don't have time to listen to the whole lecture right now, but as someone with CHF at 51 I am very interested to hear your thoughts. My CAD appears to be related to radiation and chemo I had when I was 18. Throw in some diabetes and I am a mess. EF=33%

[@ernestocaamano7818]

MI in 8/2009, bad stent and botched bypass To make it short, my EF went from 50% to 37%. Read about it and began Weigh lifting. My EF is back to 50% after 5 months Research, Weigh lifting increases EF. Good luck

[@wocket42]

a ketogenic diet might help with diabetes and the EF. Look for Dr. Erik Westman on youtube.

[@yamihami1]

What about Jardiance ?

[@annalexander6042]

I've asma on relvaar ventolin and spiritual inhaler

[@simev500]

18:44 Does a short term overload of calcium into (or depletion of sodium out of) muscle cells trigger muscle cramps? 27:13 Does plainly roasting nuts, without adding preservatives or 'natural' flavors(salt?), like peanuts(or its butter), walnuts, almonds, cashews, brazil nuts, transform the oil within them to its oxidized form? And, is the rancid smell/taste the only way to catch the peroxidation in seed oils. Can the affected oil escape detection otherwise? 31:04 How low would be too low for LDL level? 31:53 Proponents of statins therapy claim the drug attenuates inflammation. How does that squares with LDL as a first responder on the scene in an infection? If asserting that having fewer 'responders' on site would be less chaotic (the immune response-->inflammation) so to be less damaging for the blood vessel lining, then how would the infection be resolved? A correlated question is, what role do cortisones/steroids play in calming the inflammation response? 33:54 Pcsk9 inhibitors remove LdL in blood plasma into the liver. Now, which size LdL particle is this and what is the next transformation in its cycle?

[@ElGrandeSD]

What about ARBs?

[@Eliese.]

Please add ARB's as they seem to react differently in the lungs and the bowels.

[@nChristos100]

Cholesterol stuff begins around 24:30 Statins begin around 36:30

[@KenJackson_US]

I wonder how passionately the pharma industry will hate him for speaking truth.

[@susanbeever5708]

Statins stimulate TRPV1 an incretin that stimulates insulin through the neurolymphocrine system. Too much insulin causes insulin resistance. Glp-1 stimulates the glp-1 receptor that stimulates TRPV1 on lymphatic sensory neurons. Glp-1 is a diuretic and natriuretic by increasing glomerular flow and blocking sodium reabsorption from the proximal tubule of the kidney, by stimulating TRPV1 in the pelvic renal neurons and causes hyponatremia. Hyponatremia is an independent cause of bone mineral density loss. Hyponatremia hypoosmolality stimulates trpv4 and piezo-1 and leads to many diseases such as turning pre-osteoclasts into osteoclasts that break down bone, and turning monocytes into m1 macrophages that phagocytize oxidized LDL to become foamy macrophages. TRPV4 also causes the breakdown of intercellular junctions between endothelial cells seen In aneurysm. TRPV4 is found in the transcriptome of active atherosclerosis.

[@HendrikRitsema]

Best treatment for atherosclerosis: Vitamin C Why do only coronary arteries clog with cholesterol and not veins or small capillaries? Scurvy = No vitamin C in your diet. Symptom: Your blood vessels break and you bleed to death. Think of the sailor of the past. Scurvy of the heart = Just enough vitamin C from food. Symptom: Arteries around the heart are not strong enough to resist high blood pressure. Damage is repaired with cholesterol LP(a) to prevent worse. After years of repair, your arteries become clogged. Enough vitamin C supplement of at least 3000 mg. per day gives strong and flexible arteries. Cholesterol is not needed as a repair agent. Cholesterol in your coronary arteries is broken down and burned in your liver. Source KZbin: - Cardiovascular disease and vitamin C (Dr. Rath Foundation) - Ending the Cardiovascular Epidemic by Natural Means - Dr. Matthias Rath

[@098anne]

QUESTION: Is there a study of people who have reversed all three- t2 diabetes, insulinemia AND insulin resistance? Have their insulin and glucose responses healed to the point of being normal again? Or do they continue to have heightened responses? To the point: Can t2 be CURED or just put into hard controlled remission?

[@insuliniq]

At the bottom of this page on our website there is a short video highlighting a peer-reviewed clinical case study we did, published in the prestigious Journal of Diabetes Research. It is entitled “Remarkable Results” and may help answer your question: www.insuliniq.com/private-coaching

[@wocket42]

If you are searching for something that allows you to eat unlimited carbs afterwards, that does not exist. You'll always need to dial back to the point the carbs won't make you sick again. Some say this is a "hard controlled remission" and dismiss it. So it's more of a reset, but you need to stay below your (ever decreasing) own personal maximum carbs intake level.

[@vince1229]

So that means kidney patients and diabetics put on low salt diets are increasing their insulin resistance?

[@prestomattwine]

Would like to know in that Swedish study what their cholesterol levels were? I’m 60 year old male and weigh 225 lbs., from a max weight of 275 lbs in 2018. Started taking Simvastatin in December of 2008 at age 42, 40mg. and total cholesterol was always between 148-255 from 2003-2018. LDL was between 70-140. HDL in that time period has always been in the upper 30’s to 40’s, the highest was 49 in 2001-2002 when I was around 36-38 years old. My Triglycerides have ranged from as low as 51 in 03’ weight 175 to as high as 396 in 09’ weight was 220. My fasting glucose during that time period has been lowest in 05’ of 100 weight 200 to highest 131 in 2017, weight 264. Average a/1c has been 5.6. These numbers are reflected by eating a SAD diet all my life and numbers shown when I started around 2000 seeing my family doctor. In 2019 I started a low carb diet and went from 275 to 230lbs in about 6 months. In that time period between 2019 to present, I’ve fallen off and on the wagon, especially during COVID. Overall however, my eating habits have been the best they’ve ever been in my life. However, since going low carb in 2019, my Cholesterol levels have almost doubled with an average cholesterol level of 295, LDL of 180, HDL of 39 and Triglycerides 235. Glucose average 112 and a1/c has averaged 5.5. Over these years my doctor has been saying I need to go back on a statin, which he takes 10mg. of Crestor and has a couple of stents, which I do not have yet! He wanted to start me on 20mg., but I’m going to start with 5mg. and go from there. At this point I don’t know who to believe anymore, people like yourself and other KZbin influencers or the medical professionals. I know I’m doing the right thing by giving up the SAD diet overall, but as far as my lipid levels I’m afraid that these levels are too high and am going the route of trying a statin again. Dr. Bikman I value your knowledge and look forward to any opinions you might have regarding my decision.

[@insuliniq]

Thanks for your comment, and for reaching out. Because your specifics are fairly complex, you may want to consider doing an online consultation with our Medical Metabolic Health Director, Lindsay Venn. You can learn more about doing that here: www.insuliniq.com/medical-consultations

[@davidbailey6176]

I used to just assume that doctors know best, so when I was offered simvastatin by my doctor I thought it was a great idea. In my case they caused intense cramps in my polio leg. I think I might have lost my ability to walk if I cad struggled on. As it is, I gave statins up. Now, at 74, and I regularly get warned about my high cholesterol, and I regularly take no notice! The dishonesty of Big Pharma is jaw-dropping!

[@michaelskrobola8254]

Hi. I’m confused. Dr Bikman stated that it’s not good to eat before bed ( which I agree with) and stated the reason was that eating will spike glucose and insulin. The insulin will activate the sympathetic nervous system which is not good for sleep. Is this just in the context of an IR person? Will all meals spike insulin and glucose? Are there other reasons why eating before bed is not ideal? Why is eating before bed not part of the “rest and digest…parasympathetic system? Thanks

[@wocket42]

Even if you just eat a bit of protein and some fat, it will still increase body temperature and for sleep you need to lower the core temperature.

[@michaelskrobola8254]

@@wocket42 Reasonable. Thank you for your input. My question was more regarding what branch of the autonomic nervous system was more active after the eating. If it’s sympathetic that is the opposite of rest and digest

[@barbarapecka4935]

What do you think about Ezetymibe? ..... could this be ....... a middle ground between statins and no treatment?

[@bchiro100]

Dr. Bikman is a very smart guy. Iv'e been trying for 2 years to get this question answered with no success. I'm positive he would know. Why would my fasting blood glucose be 190 with a C-peptide of 1.40 and a fasting insulin of 5.4 uIU/ml? GAD-65 autoantibody

[@insuliniq]

Thanks for your question. You may want to go to our website and ask my team: www.insuliniq.com

[@rongqut7576]

"Fenofibrate" please explain this drug.

[@annalexander6042]

I feel OK

[@annalexander6042]

Need to go I have notification saying saying I am good thanks week taking my medication

[@berchtfa]

What about the infinite amount of ECRs that showed that by lowering LDL (and apoB) you lower mortality? Pathogenisis theory cant overwhelm this.

[@annalexander6042]

Cellulitis left leg little on right

[@moroniholm87]

I'm happy I don't have to reduce my salt intake. 😅 I know it's one of the ingredients in uric acid.

[@lmyers9999]

Blue zones have high cholesterol levels… which is associated with living longer… and they are insulin sensitive

[@lmyers9999]

There is no plaque in veins… which discredits the cholesterol theory from day one- nor do pregnant women and fetuses… both of who have super high cholesterol

[@DorotheasFavs]

How can I lower my blood pressure if I decide that I don’t want to take medication?

[@prunelle19]

Lower insulin with low carb/keto/carnivore diet will lower blood pressure

[@insuliniq]

You may want to create a free Basic Membership on our website which gives you access to my introductory course, “Raising Your Insulin IQ for Improved Metabolic Health”. This may really help you with your question: www.insuliniq.com

[@dimitrioseleftheriadis4191]

How much sodium can an organism approximately lose as a result of ingesting, for example, 300 ml of an ace inhibitor? (average). Would hyperkalemia be counteracted by taking a comparable amount of sodium (converted, of course to match) by mouth? thanks for the info.

[@annalexander6042]

I take seasalt

[@ld9044]

❤❤❤

[@christinebowman90]

💯

[@annalexander6042]

Ventral virgin oil I buy

[@annalexander6042]

I've just got murmur to heart I take trucility 75mls once a week the dietician said it was medicine I have blood pressure tablets and hypertension tablet to asma stomach tablet I was given aspirin that I was in hospital years ago got 6 pint blood and clear bags stuff

[@annalexander6042]

Is there a sweetie I can take in between my 2 meals a day am confused my diabetic nurse said I can eat an apple or banana

[@wocket42]

Snacking on carb rich foods is one of the causes for diabetes. If it's sweet, but does not contain any carbs, it may be okay, but some artificial sweeteners are not good long term. Obviously if you are taking insulin, you need to prevent hypoglycemia. Best way is to lower carb content of main meals so you need less and less insulin.

[@annalexander6042]

My dr won't allow me come of any of my medication

[@insuliniq]

Hi Anna. Thanks for your comment. There are a couple of resources for “working with your doctor” inside my free introductory course called, “Raising Your Insulin IQ for Improved Metabolic Health” that may help you. Just create a free Basic Membership on my website for access: www.insuliniq.com

[@annalexander6042]

I test my there below 9 .0

[@Helen-nv8el]

Thank you Ben. I will continue to refuse my Dr's advice to take statins.

[@KenJackson_US]

Me too.

[@annalexander6042]

I don't have beta blockers

[@MartinSKatz]

We all give you a big pass to disrespect the medical group think.

[@steponroach]

ldl, scurvy, leaky epithelial

[@annalexander6042]

I go to church a lot

[@annalexander6042]

I drink a lot get thirsty

[@kouritasvonkafthor468]

I follow you on KZbin and any doctor who backs up their opinions with research. Sorry to say it but all of you are driving us to a dead end. I am 65 years old and until today I had no problems with my health. In a last general blood test I had the following result. Triglycerides 86ml/dl, uric acid 6.5ml/dl cholesterol 213ml/dl HDL 50ml/dl LDL140ml/dl blood pressure average diastolic 65 and systolic 105. Fasting blood glucose 90mg/dl and two hours after eating 125mg/dl ApoB 92. My doctor saw these blood markers and tells me that I will have to be on statins for life anyway. When I asked him what his personal opinion is, he replied that these are the guidelines of the European Society of Cardiology and he has no personal opinion. In literally five minutes of the hour he finished the exam. What is your opinion? Should I take statins or not? By speaking your opinion, you have no responsibility. You can take my case as a case-study. My weight is 81 kg and my height is 183 cm

[@annalexander6042]

Am nearly 70 I don't want any operation s dr

[@annalexander6042]

I have been bothered with my kidneys

[@annalexander6042]

Don't take alcohol

[@annalexander6042]

I've diabetes

[@wocket42]

Type 2? Why?

[@annalexander6042]

Can't take water pills I am just better now I use to wet the bed not long stopped it I can't take water pills

[@annalexander6042]

Don't understand sorry