Intro to F Element Project

In this lecture for the July 2022 GEP New Member Training, Professor Sarah C. R. Elgin from Washington University in St. Louis describes the research aims for the Drosophila F Element Expansion project.
The lecture begins with a brief overview of the C-value paradox, the impact of transposable elements on eukaryotic genomes, and the packaging of DNA into chromatin. The lecture then presents the unusual characteristics of the Muller F Elements in D. melanogaster and in other Drosophila species based on past studies by the Elgin Lab, GEP faculty and students, and other researchers (e.g., the modENCODE project). The presentation concludes with the goals for the comparative analysis of four Drosophila species where the F Elements have undergone different levels of expansion, and a summary of the unusual features (e.g., expansion of coding spans, pseudogene clusters) that have been identified by GEP students as part of their annotations of the D. ananassae F Element.
Special thanks to Logan Cohen (Worcester State University) for his manual review of the subtitles to ensure this video is accessible to our students!
-
Learn more about the F Element Project: thegep.org/pro...
Learn more about the Genomics Education Partnership: thegep.org​
Follow GEP on Twitter: / gep_cure​
--
-